Multi-omics analysis in inclusion body myositis identifies mir-16 responsible for HLA overexpression.

Authors: Wijnbergen, Daphne¹ (AUTHOR) D.Wijnbergen@lumc.nl, Johari, Mridul^2,3,4 (AUTHOR), Ozisik, Ozan⁵ (AUTHOR), 't Hoen, Peter A.C.⁶ (AUTHOR), Ehrhart, Friederike⁷ (AUTHOR), Baudot, Anaïs^8,9,10 (AUTHOR), Evelo, Chris T.¹¹ (AUTHOR), Udd, Bjarne^3,4,12 (AUTHOR), Roos, Marco¹ (AUTHOR), Mina, Eleni¹ (AUTHOR)

Source: Orphanet Journal of Rare Diseases. 1/15/2025, Vol. 20 Issue 1, p1-10. 10p.

Subject Terms: *INCLUSION body myositis, *LIFE sciences, *ANTIGEN processing, *RIBOSOMAL RNA, *MUSCLE diseases, *MYOSITIS

Serum creatine kinase elevation following tyrosine kinase inhibitor treatment in cancer patients: Symptoms, mechanism, and clinical management.

Authors: Zhang, Hang¹ (AUTHOR), To, Kenneth K. W.¹ (AUTHOR) kennethto@cuhk.edu.hk

Source: CTS: Clinical & Translational Science. Nov2024, Vol. 17 Issue 11, p1-27. 27p.

Subject Terms: *INCLUSION body myositis, *PROTEIN-tyrosine kinase inhibitors, *CREATINE kinase, *MEDICAL supplies, *ENERGY metabolism

Association between ZASP/LDB3 Pro26Ser and Inclusion Body Myopathy.

Authors: Piga, Daniela¹ (AUTHOR) daniela.piga@policlinico.mi.it, Zanotti, Simona² (AUTHOR), Ripolone, Michela² (AUTHOR), Napoli, Laura² (AUTHOR), Ciscato, Patrizia² (AUTHOR), Gibertini, Sara³ (AUTHOR), Maggi, Lorenzo³ (AUTHOR), Fortunato, Francesco⁴ (AUTHOR), Rigamonti, Andrea⁵ (AUTHOR), Ronchi, Dario^1,4 (AUTHOR), Comi, Giacomo Pietro^1,4 (AUTHOR), Corti, Stefania^2,4 (AUTHOR) daniela.piga@policlinico.mi.it, Sciacco, Monica^1,2 (AUTHOR)

Source: International Journal of Molecular Sciences. Jun2024, Vol. 25 Issue 12, p6547. 9p.

Subject Terms: *INCLUSION body myositis, *CELLULAR inclusions, *NEMALINE myopathy, *MUSCLE weakness, *MYOSITIS, *MUSCLE diseases, *NUCLEOTIDE sequencing

Features of Swallowing Function in Sporadic Inclusion Body Myositis: Preliminary Evidence Using Well-Tested Assessment Frameworks.

Authors: Ambrocio, Kevin Renz¹, Aggarwal, Rohit^2,3, Lacomis, David^4,5, Zhang, Xingyu¹, (Focht) Garand, Kendrea L.^1,6, kgarand@pitt.edu

Source: American Journal of Speech-Language Pathology; Nov2024, Vol. 33 Issue 6, p2793-2804, 12p

Sporadic Inclusion Body Myositis at the Crossroads between Muscle Degeneration, Inflammation, and Aging.

Authors: Guglielmi, Valeria^1,2 (AUTHOR) vguglielmi@sbpdiscovery.org, Cheli, Marta³ (AUTHOR) marta.cheli@univr.it, Tonin, Paola³ (AUTHOR) paola.tonin@univr.it, Vattemi, Gaetano³ (AUTHOR) gaetano.vattemi@univr.it

Source: International Journal of Molecular Sciences. Mar2024, Vol. 25 Issue 5, p2742. 32p.

Subject Terms: *INCLUSION body myositis, *MYOSITIS, *CYTOTOXIC T cells, *AGING, *MUSCLE weakness, *OLDER people

Loss of TDP‐43 Splicing Repression Occurs in Myonuclei of Inclusion Body Myositis Patients.

Authors: Ikenaga, Chiseko¹ (AUTHOR), Wilson, Andrew B.¹ (AUTHOR), Irwin, Katherine E.^2,3 (AUTHOR), Peethambaran Mallika, Aswathy² (AUTHOR), Kilgore, Collin¹ (AUTHOR), Sinha, Irika R.^2,3 (AUTHOR), Michelle, Elizabeth H.¹ (AUTHOR), Ling, Jonathan P.² (AUTHOR), Wong, Philip C.^2,3 (AUTHOR) wong@jhmi.edu, Lloyd, Thomas E.^1,3,4 (AUTHOR) thomas.lloyd@bcm.edu

Source: Annals of Neurology. Apr2025, Vol. 97 Issue 4, p629-641. 13p.

Subject Terms: *INCLUSION body myositis, *BIOMARKERS, *THERAPEUTICS, *TDP-43 proteinopathies, *GENETIC regulation, *SKELETAL muscle, *BIOPSY, *PEPTIDES

Emerging mechanisms and therapeutics in inflammatory muscle diseases.

Authors: Wischnewski, Sven¹ (AUTHOR), Rausch, Hans-Werner^1,2 (AUTHOR), Ikenaga, Chiseko^3,4 (AUTHOR), Leipe, Jan^5,6,7 (AUTHOR), Lloyd, Thomas E.^1,3,8,9 (AUTHOR) thomas.lloyd@bcm.edu, Schirmer, Lucas^1,2,6,10 (AUTHOR) lucas.schirmer@medma.uni-heidelberg.de

Source: Trends in Pharmacological Sciences. Mar2025, Vol. 46 Issue 3, p249-263. 15p.

Subject Terms: *INCLUSION body myositis, *THERAPEUTICS, *MYOSITIS, *IDIOPATHIC diseases, *CHIMERIC antigen receptors, *T cells

Human induced pluripotent stem cell-derived myotubes to model inclusion body myositis.

Authors: Cantó-Santos, Judith^1,2 (AUTHOR), Valls-Roca, Laura^1,2 (AUTHOR), Tobías, Ester^1,2 (AUTHOR), García-García, Francesc Josep^1,2 (AUTHOR), Guitart-Mampel, Mariona^1,2 (AUTHOR), Andújar-Sánchez, Félix^1,2 (AUTHOR), Vilaseca-Capel, Adrià^1,2 (AUTHOR), Esteve-Codina, Anna^3,4 (AUTHOR), Martín-Mur, Beatriz³ (AUTHOR), Padrosa, Joan^1,2 (AUTHOR), Peruga, Emma⁵ (AUTHOR), Madrigal, Irene^2,5 (AUTHOR), Segalés, Paula^6,7 (AUTHOR), García-Ruiz, Carmen^6,7 (AUTHOR), Fernández-Checa, José Carlos^6,7 (AUTHOR), Moreno-Lozano, Pedro J.^1,2 (AUTHOR), O'Callaghan, Albert Selva⁸ (AUTHOR), Sevilla, Ana^9,10 (AUTHOR) anasevilla@ub.edu, Milisenda, José César^1,2 (AUTHOR) jcmilise@clinic.cat, Garrabou, Glòria^1,2 (AUTHOR) garrabou@clinic.cat

Source: Acta Neuropathologica Communications. 2/21/2025, Vol. 13 Issue 1, p1-18. 18p.

Subject Terms: *INCLUSION body myositis, *MEDICAL sciences, *INDUCED pluripotent stem cells, *CYTOCHROME oxidase, *MUSCLE weakness

Muscle magnetic resonance imaging findings in patients with idiopathic inflammatory myopathies.

Authors: Hamano, Tadanori¹ (AUTHOR) hamano@u-fukui.ac.jp, Kamisawa, Tomoko¹ (AUTHOR), Sanada, Sayaka¹ (AUTHOR), Hayashi, Kouji^1,2 (AUTHOR)

Source: Clinical & Experimental Neuroimmunology. Feb2025, Vol. 16 Issue 1, p72-83. 12p.

Subject Terms: *INCLUSION body myositis, *MYOSITIS, *MUSCLE weakness, *MAGNETIC resonance imaging, *MUSCULAR atrophy

Interferons in myositis: Pathogenesis and therapy.

Authors: Tawara, Nozomu¹ (AUTHOR) nozomonist@gmail.com

Source: Clinical & Experimental Neuroimmunology. Feb2025, Vol. 16 Issue 1, p64-71. 8p.

Subject Terms: *INCLUSION body myositis, *IDIOPATHIC diseases, *DERMATOMYOSITIS, *MITOCHONDRIAL pathology, *MYOSITIS

Myositis‐specific/associated autoantibodies as diagnostic keys and disease drivers.

Authors: Yamashita, Satoshi¹ (AUTHOR) y-stsh@iuhw.ac.jp

Source: Clinical & Experimental Neuroimmunology. Feb2025, Vol. 16 Issue 1, p44-54. 11p.

Subject Terms: *INCLUSION body myositis, *INTERSTITIAL lung diseases, *AUTOANTIBODIES, *SYMPTOMS, *DERMATOMYOSITIS

Update on pathology of inflammatory myopathy.

Authors: Uruha, Akinori¹ (AUTHOR) a.uruha@gmail.com, Uruha, Satoko¹ (AUTHOR)

Source: Clinical & Experimental Neuroimmunology. Feb2025, Vol. 16 Issue 1, p55-63. 9p.

Subject Terms: *INCLUSION body myositis, *CONNECTIVE tissue diseases, *TYPE I interferons, *MYOSITIS, *DERMATOMYOSITIS

Refining the clinical and therapeutic spectrum of granulomatous myositis from a large cohort of patients.

Authors: Lauletta, Antonio¹ (AUTHOR) antonio.lauletta@uniroma1.it, de Le Hoye, Laurène² (AUTHOR), Leonard-Louis, Sarah³ (AUTHOR), Garibaldi, Matteo^1,4 (AUTHOR), Allenbach, Yves⁵ (AUTHOR), Benveniste, Olivier⁵ (AUTHOR)

Source: Journal of Neurology. Feb2025, Vol. 272 Issue 2, p1-13. 13p.

Subject Terms: *INCLUSION body myositis, *CROHN'S disease, *MUSCLE weakness, *TREATMENT effectiveness, *SYMPTOMS

Inclusion body myositis. Genetics, biomarkers and muscle biopsy.

Authors: Mavroudis, Ioannis¹ (AUTHOR) ioannis.mavroudis@nhs.net, Petridis, Foivos² (AUTHOR), Kazis, Dimitrios² (AUTHOR)

Source: International Journal of Neuroscience. Dec2023, Vol. 133 Issue 11, p1211-1217. 7p.

Subject Terms: *INCLUSION body myositis, *MYOSITIS, *GENETICS, *BIOMARKERS, *THERAPEUTICS, *STAIR climbing

Prominent mitochondrial pathology in a case of refractory dermatomyositis: coincidence or concause?

Authors: Lauletta, Antonio¹ (AUTHOR) antonio.lauletta@uniroma1.it, De Carolis, Lanfranco¹ (AUTHOR), Teresi, Valentina¹ (AUTHOR), Fionda, Laura¹ (AUTHOR), Leonardi, Luca¹ (AUTHOR), Ceccanti, Marco² (AUTHOR), Costanzo, Rocco¹ (AUTHOR), Rossini, Elena¹ (AUTHOR), Tufano, Laura¹ (AUTHOR), Merlonghi, Gioia¹ (AUTHOR), Morino, Stefania¹ (AUTHOR), Garibaldi, Matteo¹ (AUTHOR)

Source: Neurological Sciences. Dec2023, Vol. 44 Issue 12, p4525-4529. 5p.

Subject Terms: *DERMATOMYOSITIS, *INCLUSION body myositis, *POLYMYOSITIS, *MITOCHONDRIAL pathology, *MUSCLE weakness, *COINCIDENCE, *PATIENT-professional relations

Cytotoxic immune cells do not affect TDP-43 and p62 sarcoplasmic aggregation but influence TDP-43 localisation.

Authors: McCord, Bryony¹ (AUTHOR), Day, Richard M.¹ (AUTHOR) r.m.day@ucl.ac.uk

Source: Scientific Reports. 11/20/2023, Vol. 13 Issue 1, p1-12. 12p.

Subject Terms: *INCLUSION body myositis, *MUSCLE proteins, *CELL aggregation, *CYTOTOXINS, *T cells

Inclusion body myositis—health-related quality of life and care situation during phases of the "patience journey" in Germany: results from a qualitative study.

Authors: Senn, Katja C.¹ (AUTHOR) katja.senn@uni-bayreuth.de, Thiele, Simone² (AUTHOR), Gumbert, Laura^1,3 (AUTHOR), Krause, Sabine² (AUTHOR), Walter, Maggie C.² (AUTHOR), Nagels, Klaus H.¹ (AUTHOR)

Source: Health & Quality of Life Outcomes. 10/10/2023, Vol. 21 Issue 1, p1-11. 11p.

Subject Terms: *INCLUSION body myositis, *QUALITY of life, *PATIENT experience, *MEDICAL care, *QUALITATIVE research

Geographic Terms: GERMANY

Retrospective Study Shows That Serum Levels of Chemokine CXCL10 and Cytokine GDF15 Support a Diagnosis of Sporadic Inclusion Body Myositis and Immune-Mediated Necrotizing Myopathy.

Authors: De Paepe, Boel^1,2 (AUTHOR) boel.depaepe@ugent.be, Bracke, Ken R.³ (AUTHOR) ken.bracke@ugent.be, De Bleecker, Jan L.^1,2 (AUTHOR)

Source: Brain Sciences (2076-3425). Oct2023, Vol. 13 Issue 10, p1369. 12p.

Subject Terms: *INCLUSION body myositis, *MYOSITIS, *CHEMOKINES, *GROWTH differentiation factors, *NEUROMUSCULAR diseases, *MUSCLE diseases

Influence of Inflammatory Cytokines IL-1β and IFNγ on Sarcoplasmic Aggregation of p62 and TDP-43 in Myotubes.

Authors: McCord, Bryony¹ (AUTHOR), Day, Richard M.¹ (AUTHOR)

Source: Mediators of Inflammation. 9/12/2023, p1-13. 13p.

Subject Terms: *INCLUSION body myositis, *PROTEIN expression, *INFLAMMATORY mediators, *IMAGE analysis, *SKELETAL muscle

Identification of Unique microRNA Profiles in Different Types of Idiopathic Inflammatory Myopathy.

Authors: Muñoz-Braceras, Sandra¹ (AUTHOR) iago.pinalfernandez@nih.gov, Pinal-Fernandez, Iago^1,2 (AUTHOR) lchrist4@jhmi.edu, Casal-Dominguez, Maria^1,2 (AUTHOR) katherine.pak@nih.gov, Pak, Katherine¹ (AUTHOR) jcmilise@clinic.cat, Milisenda, José César^1,3,4 (AUTHOR) jmgrau@clinic.cat, Lu, Shajia⁵ (AUTHOR) lushajia@ep.niams.nih.gov, Gadina, Massimo⁵ (AUTHOR) gadinama@mail.nih.gov, Naz, Faiza⁶ (AUTHOR) faiza.naz@nih.gov, Gutierrez-Cruz, Gustavo⁶ (AUTHOR) gutierrg@exchange.nih.gov, Dell'Orso, Stefania⁶ (AUTHOR), Torres-Ruiz, Jiram^1,7 (AUTHOR), Grau-Junyent, Josep Maria^3,4 (AUTHOR), Selva-O'Callaghan, Albert⁸ (AUTHOR) albert.selva@vallhebron.cat, Paik, Julie J.⁹ (AUTHOR) jpaik1@jhmi.edu, Albayda, Jemima⁹ (AUTHOR) jalbayd1@jhmi.edu, Christopher-Stine, Lisa^2,9 (AUTHOR) acorse@jhmi.edu, Lloyd, Thomas E.² (AUTHOR), Corse, Andrea M.² (AUTHOR), Mammen, Andrew L.^1,2,9 (AUTHOR) sandra.munozbraceras@nih.gov

Source: Cells (2073-4409). Sep2023, Vol. 12 Issue 17, p2198. 13p.

Subject Terms: *INCLUSION body myositis, *TYPE I interferons, *GENE expression, *MUSCLE diseases, *MICRORNA