Non-invasive strategy: Developing a topical IL-4Rα-specific nanobody for the treatment of allergic airway diseases

Authors: Taeyoung Ahn, Dong Hyuk Lee, GeunAh Kim, JiHyun Kim, Joon-Sang Park, Hyung-Ju Cho, Joo Young Kim

Source: Materials Today Bio, Vol 27, Iss , Pp 101148- (2024)

Subject Terms: Allergic rhinitis, Interleukin-4 receptor α, Nanobody, In-silico affinity maturation, Non-invasive treatment, Medicine (General), R5-920, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2590006424002072; https://doaj.org/toc/2590-0064

Access URL: https://doaj.org/article/f465aa55d3fd4613a27ed8513b7aacb9

In Silico Maturation of a Nanomolar Antibody against the Human CXCR2

Authors: Damiano Buratto, Yue Wan, Xiaojie Shi, Guang Yang, Francesco Zonta

Source: Biomolecules, Vol 12, Iss 9, p 1285 (2022)

Subject Terms: in silico affinity maturation, MM-PBSA (Molecular Mechanic/Poisson-Boltzmann Surface Area), CXCR2, monoclonal antibodies, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.mdpi.com/2218-273X/12/9/1285; https://doaj.org/toc/2218-273X

Access URL: https://doaj.org/article/1f7384aa3c224219a7d33021dd218cc3