Centrobin serves as a safeguard to guide timely centriole maturation during the cell cycle

Authors: Dohyong Lee, Sungjin Ryu, Ji Hwa Hea, Globinna Kim, In-Jeoung Baek, Young Hoon Sung, Kunsoo Rhee

Source: Scientific Reports, Vol 15, Iss 1, Pp 1-15 (2025)

Subject Terms: Centrobin, Centriole, Distal appendage, Centriole maturation, Cell cycle, Plk1, Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/3cdb7874ef694c1181ba5d804749f7b6

CD47;Rag2;IL-2rγ triple knock-out mice pre-conditioning with busulfan could be a novel platform for generating hematopoietic stem cells engrafted humanized mice

Authors: Kang-Hyun Kim, Sang-wook Lee, In-Jeoung Baek, Hye-Young Song, Seon-Ju Jo, Je-Won Ryu, Seung-Hee Ryu, Jin-Hee Seo, Jong-Choon Kim, Seung-Ho Heo

Source: Frontiers in Immunology, Vol 15 (2024)

Subject Terms: busulfan, cd47, hematopoietic stem cells, humanized mice, signal-regulatory protein alpha, total body irradiation, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2024.1365946/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/ae3bc8ca5c8d4a7c8150cbe28c726df4

PIBF1 regulates trophoblast syncytialization and promotes cardiovascular development

Authors: Jong Geol Lee, Jung-Min Yon, Globinna Kim, Seul-Gi Lee, C-Yoon Kim, Seung-A Cheong, Hyun-Yi Kim, Jiyoung Yu, Kyunggon Kim, Young Hoon Sung, Hyun Ju Yoo, Dong-Cheol Woo, Jin Kyung Rho, Chang Hoon Ha, Chan-Gi Pack, Seak Hee Oh, Joon Seo Lim, Yu Mi Han, Eui-Ju Hong, Je Kyung Seong, Han-Woong Lee, Sang-Wook Lee, Ki-Up Lee, Chong Jai Kim, Sang-Yoon Nam, You Sook Cho, In-Jeoung Baek

Source: Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/0ca95e30cf3f492685e8ec10572f9c46

Blood flow patterns switch VEGFR2 activity through differential S-nitrosylation and S-oxidation

Authors: Dong Hoon Kang, Yerin Kim, Seongchun Min, Su Youn Lee, Ka Young Chung, In-Jeoung Baek, Kihwan Kwon, Hanjoong Jo, Sang Won Kang

Source: Cell Reports, Vol 42, Iss 11, Pp 113361- (2023)

Subject Terms: CP: Cell biology, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211124723013736; https://doaj.org/toc/2211-1247

Access URL: https://doaj.org/article/9b602d14b06f45a29435838d47121b5e

Sphingosine 1-Phosphate Receptor 4 Promotes Nonalcoholic Steatohepatitis by Activating NLRP3 InflammasomeSummary

Authors: Chung Hwan Hong, Myoung Seok Ko, Jae Hyun Kim, Hyunkyung Cho, Chi-Ho Lee, Ji Eun Yoon, Ji-Young Yun, In-Jeoung Baek, Jung Eun Jang, Seung Eun Lee, Yun Kyung Cho, Ji Yeon Baek, Soo Jin Oh, Bong Yong Lee, Joon Seo Lim, Jongkook Lee, Sean M. Hartig, Laura Conde de la Rosa, Carmen Garcia-Ruiz, Ki-Up Lee, Jose C. Fernández-Checa, Ji Woong Choi, Sanghee Kim, Eun Hee Koh

Source: Cellular and Molecular Gastroenterology and Hepatology, Vol 13, Iss 3, Pp 925-947 (2022)

Subject Terms: Hepatic Macrophages, Ca++, Functional Antagonist, S1P, Diseases of the digestive system. Gastroenterology, RC799-869

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2352345X21002526; https://doaj.org/toc/2352-345X

Access URL: https://doaj.org/article/9e46029d27bf4714b479e2ac2776f414

PPARα−ACOT12 axis is responsible for maintaining cartilage homeostasis through modulating de novo lipogenesis

Authors: Sujeong Park, In-Jeoung Baek, Ji Hyun Ryu, Churl-Hong Chun, Eun-Jung Jin

Source: Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/32daeeaff75a45adb44b1fda53157388

SLIT3 promotes myogenic differentiation as a novel therapeutic factor against muscle loss

Authors: Han Jin Cho, Hyeonmok Kim, Young‐Sun Lee, Sung Ah Moon, Jin‐Man Kim, Hanjun Kim, Min Ji Kim, Jiyoung Yu, Kyunggon Kim, In‐Jeoung Baek, Seung Hun Lee, Kyong Hoon Ahn, Sungsub Kim, Jong‐Sun Kang, Jung‐Min Koh

Source: Journal of Cachexia, Sarcopenia and Muscle, Vol 12, Iss 6, Pp 1724-1740 (2021)

Subject Terms: Slit3, Robo2, LRRD2, Muscle loss, Diseases of the musculoskeletal system, RC925-935, Human anatomy, QM1-695

File Description: electronic resource

Relation: https://doaj.org/toc/2190-5991; https://doaj.org/toc/2190-6009

Access URL: https://doaj.org/article/b0e084ba5f644c6f8760813b54f280fa

Deficiency of peroxisomal NUDT7 stimulates de novo lipogenesis in hepatocytes

Authors: Jinsoo Song, In-Jeoung Baek, Sujeong Park, Jinjoo Oh, Deokha Kim, Kyung Song, Mi Kyung Kim, Hye Won Lee, Byoung Kuk Jang, Eun-Jung Jin

Source: iScience, Vol 25, Iss 10, Pp 105135- (2022)

Subject Terms: Biological sciences, Human metabolism, Cell biology, Transcriptomics, Science

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2589004222014079; https://doaj.org/toc/2589-0042

Access URL: https://doaj.org/article/38e8b71a9a17437cbd7398d78c09f578

Progesterone receptor membrane component 1 reduces cardiac steatosis and lipotoxicity via activation of fatty acid oxidation and mitochondrial respiration

Authors: Sang R. Lee, Jun H. Heo, Seong Lae Jo, Globinna Kim, Su Jung Kim, Hyun Ju Yoo, Kyu-Pil Lee, Hyo-Jung Kwun, Hyun-Jin Shin, In-Jeoung Baek, Eui-Ju Hong

Source: Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/bb10f57b600240b4adc861e06e95a419

Absence of progesterone receptor membrane component 1 reduces migration and metastasis of breast cancer

Authors: Sang R. Lee, Young Ho Lee, Seong Lae Jo, Jun H. Heo, Globinna Kim, Geun-Shik Lee, Beum-Soo An, In-Jeoung Baek, Eui-Ju Hong

Source: Cell Communication and Signaling, Vol 19, Iss 1, Pp 1-11 (2021)

Subject Terms: Pgrmc1, Breast cancer, Lung, Metastasis, Migration, Medicine, Cytology, QH573-671

File Description: electronic resource

Relation: https://doaj.org/toc/1478-811X

Access URL: https://doaj.org/article/043983de21534ba3aa0a3676a470e544

Development of a novel knockout model of retinitis pigmentosa using Pde6b-knockout Long–Evans rats

Authors: Jee Myung Yang, Bora Kim, Jiehoon Kwak, Min Kyung Lee, Jeong Hoon Kim, In-Jeoung Baek, Young Hoon Sung, Joo Yong Lee

Source: Frontiers in Medicine, Vol 9 (2022)

Subject Terms: Pde6b, Long–Evans rats, retinitis pigmentosa, bone spicule, retinal degeneration, electroretinogram, Medicine (General), R5-920

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fmed.2022.909182/full; https://doaj.org/toc/2296-858X

Access URL: https://doaj.org/article/8048490e05764f16a819743ae56b0cf8

PGRMC1 Ablation Protects from Energy-Starved Heart Failure by Promoting Fatty Acid/Pyruvate Oxidation

Authors: Sang R. Lee, Moeka Mukae, Kang Joo Jeong, Se Hee Park, Hi Jo Shin, Sang Woon Kim, Young Suk Won, Hyo-Jung Kwun, In-Jeoung Baek, Eui-Ju Hong

Source: Cells, Vol 12, Iss 5, p 752 (2023)

Subject Terms: Pgrmc1, heart, starvation, ischemia, metabolism, Cytology, QH573-671

File Description: electronic resource

Relation: https://www.mdpi.com/2073-4409/12/5/752; https://doaj.org/toc/2073-4409

Access URL: https://doaj.org/article/028fd74782ec4044b4f71bababb17aa9

Loss of progesterone receptor membrane component 1 promotes hepatic steatosis via the induced de novo lipogenesis

Authors: Sang R. Lee, Sun Woo Kwon, Pelin Kaya, Young Ho Lee, Jong Geol Lee, Globinna Kim, Geun-Shik Lee, In-Jeoung Baek, Eui-Ju Hong

Source: Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)

Subject Terms: Progesterone Receptor Membrane Component 1 (PGRMC1), Non-alcoholic Steatohepatitis (NASH), Non-alcoholic Fatty Liver Disease (NAFLD), NAFLD Development, Excess Energy Conditions, Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/0178d83a786046cfa39dfbfd36639d30

Dysregulation of the NUDT7-PGAM1 axis is responsible for chondrocyte death during osteoarthritis pathogenesis

Authors: Jinsoo Song, In-Jeoung Baek, Churl-Hong Chun, Eun-Jung Jin

Source: Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/91ec857969d7456dbd74a7a0a8bc0425

Enhanced Antitumor Immune Response in 2′-5′ Oligoadenylate Synthetase-Like 1- (OASL1-) Deficient Mice upon Cisplatin Chemotherapy and Radiotherapy

Authors: Chan Kyu Sim, Jung Hoon Lee, In-Jeoung Baek, Sang-Wook Lee, Myeong Sup Lee

Source: Journal of Immunology Research, Vol 2019 (2019)

Subject Terms: Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://doaj.org/toc/2314-8861; https://doaj.org/toc/2314-7156

Access URL: https://doaj.org/article/c2e175f85b924fe28e069f8273424992

AUY922 effectively overcomes MET- and AXL-mediated resistance to EGFR-TKI in lung cancer cells.

Authors: Yun Jung Choi, Seon Ye Kim, Kwang Sup So, In-Jeoung Baek, Woo Sung Kim, Se Hoon Choi, Jae Cheol Lee, Trever G Bivona, Jin Kyung Rho, Chang-Min Choi

Source: PLoS ONE, Vol 10, Iss 3, p e0119832 (2015)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC4363657?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/c3238bca2dfb4341808551d59df5699e

Hepatic progesterone receptor membrane component 1 attenuates ethanol-induced liver injury by reducing acetaldehyde production and oxidative stress.

Authors: Seong-Lae Jo¹, In-Jeoung Baek², Je-Won Ko¹, Hyo-Jung Kwun¹, Hyun-Jin Shin¹, Eui-Ju Hong¹ ejhong@cnu.ac.kr

Source: American Journal of Physiology: Gastrointestinal & Liver Physiology. Jun2023, Vol. 324 Issue 6, pG442-G451. 10p.

Subject Terms: *ACETALDEHYDE, *PROGESTERONE receptors, *ALCOHOLIC liver diseases, *OXIDATIVE stress, *LIVER injuries, *HAZARDOUS substances

Association between ARID2 and RAS-MAPK pathway in intellectual disability and short stature.

Authors: Eungu Kang, Minji Kang, Younghee Ju, Sang-Joon Lee, Yong-Seok Lee, Dong-Cheol Woo, Young Hoon Sung, In-Jeoung Baek, Woo Hyun Shim, Woo-Chan Son, In Hee Choi, Eul-Ju Seo, Han-Wook Yoo, Yong-Mahn Han, Beom Hee Lee

Source: Journal of Medical Genetics; Nov2021, Vol. 58 Issue 11, p767-777, 11p

Sphingomyelin synthase 1 mediates hepatocyte pyroptosis to trigger non-alcoholic steatohepatitis.

Authors: Eun Hee Koh, Ji Eun Yoon, Myoung Seok Ko, Jaechan Leem, Ji-Young Yun, Chung Hwan Hong, Yun Kyung Cho, Seung Eun Lee, Jung Eun Jang, Ji Yeon Baek, Hyun Ju Yoo, Su Jung Kim, Chang Ohk Sung, Joon Seo Lim, Won-Il Jeong, Sung Hoon Back, In-Jeoung Baek, Torres, Sandra, Solsona-Vilarrasa, Estel, de la Rosa, Laura Conde

Source: Gut; Oct2021, Vol. 70 Issue 10, p1954-1964, 11p

Subject Terms: FATTY liver, NLRP3 protein, NON-alcoholic fatty liver disease, ALANINE aminotransferase, PYROPTOSIS, HIGH mobility group proteins, SPHINGOMYELIN

Beta-carotene prevents the spermatogenic disorders induced by exogenous scrotal hyperthermia through modulations of oxidative stress, apoptosis, and androgen biosynthesis in mice.

Authors: Jung-Min Yon, Jae Seung Kim, Chunmei Lin, Seul Gi Park, Lee Wha Gwon, Jong-Geol Lee, In-Jeoung Baek, Sang-Seop Nahm, Sang-Yoon Nam

Source: Korean Journal of Veterinary Research; 2019, Vol. 59 Issue 2, p59-67, 9p

Subject Terms: OXIDATIVE stress, GLUTATHIONE peroxidase, FEVER, CELL death, LEYDIG cells, BIOSYNTHESIS