Characterization of PgIJ, a Glycosyltransferase in the Campylobacter concisus N-Linked Protein Glycosylation Pathway that Expands Glycan Diversity

Authors: Arbour, Christine A., Vuksanovic, Nemanja, Bernstein, Hannah M., Allen, Karen N., Imperiali, Barbara

Source: BIOCHEMISTRY -PENNSYLVANIA THEN WASHINGTON-. 63(1):141-151

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Deploying solid-phase synthesis to access thymine-containing nucleoside analogs that inhibit DNA repair nuclease SNM1AElectronic supplementary information (ESI) available. See DOI: https://doi.org/10.1039/d3ob00836c

Authors: Arbour, Christine A., Fay, Ellen M., McGouran, Joanna F., Imperiali, Barbara

Source: Organic & biomolecular chemistry. 21(28):5873-5879

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Engineered Glycan-Binding Proteins for Recognition of the Thomsen—Friedenreich Antigen and Structurally Related Disaccharides

Authors: Ward, Elizabeth M., Zamora, Cristina Y., Schocker, Nathaniel S., Ghosh, Soumi, Kizer, Megan E., Imperiali, Barbara

Source: ACS chemical biology. 18(1):70-80

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN631616833&indx=1&recIds=ETOCRN631616833

Synergistic computational and experimental studies of a phosphoglycosyl transferase membrane/ligand ensemble

Authors: Majumder, Ayan, Vuksanovic, Nemanja, Ray, Leah C., Bernstein, Hannah M., Allen, Karen N., Imperiali, Barbara, Straub, John E.

Source: In Journal of Biological Chemistry October 2023 299(10)

A generalizable protocol for expression and purification of membrane-bound bacterial phosphoglycosyl transferases in liponanoparticles

Authors: Dodge, Greg J., Bernstein, Hannah M., Imperiali, Barbara

Source: In Protein Expression and Purification July 2023 207

Probing Monotopic Phosphoglycosyl Transferases from Complex Cellular Milieu

Authors: Anderson, Alyssa J., Seebald, Leah M., Arbour, Christine A., Imperiali, Barbara

Source: ACS chemical biology. 17(11):3191-3197

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Glycoconjugate pathway connections revealed by sequence similarity network analysis of the monotopic phosphoglycosyl transferases

Authors: O’Toole, Katherine H., Imperiali, Barbara, Allen, Karen N.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2021 Jan . 118(4), 1-9.

Access URL: https://www.jstor.org/stable/27006047

Strategies and Tactics for the Development of Selective Glycan-Binding Proteins

Authors: Ward, Elizabeth M., Kizer, Megan E., Imperiali, Barbara

Source: ACS chemical biology. 16(10):1795-1813

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN627827603&indx=1&recIds=ETOCRN627827603

Proteome-wide bioinformatic annotation and functional validation of the monotopic phosphoglycosyl transferase superfamily.

Authors: Durand, Theo, Dodge, Greg J., Siuda, Roxanne P., Higinbotham, Hugh R., Arbour, Christine A., Ghosh, Soumi, Allen, Karen N., Imperiali, Barbara

Source: Proceedings of the National Academy of Sciences of the United States of America; 12/3/2024, Vol. 121 Issue 49, p1-26, 38p

Subject Terms: MEMBRANE proteins, BIOCHEMICAL substrates, TRANSFERASES, PROTEIN synthesis, BIOSYNTHESIS

Uridine natural products: Challenging targets and inspiration for novel small molecule inhibitors

Authors: Arbour, Christine A., Imperiali, Barbara

Source: In Bioorganic & Medicinal Chemistry 15 September 2020 28(18)

Co‐conserved sequence motifs are predictive of substrate specificity in a family of monotopic phosphoglycosyl transferases

Authors: Anderson, Alyssa J., Dodge, Greg J., Allen, Karen N., Imperiali, Barbara

Source: Protein science. 32(6)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100185498287.0x000001&indx=1&recIds=ETOCvdc_100185498287.0x000001

Bacterial carbohydrate diversity — a Brave New World

Authors: Imperiali, Barbara

Source: In Current Opinion in Chemical Biology December 2019 53:1-8

Structural and mechanistic themes in glycoconjugate biosynthesis at membrane interfaces

Authors: Allen, Karen N, Imperiali, Barbara

Source: In Current Opinion in Structural Biology December 2019 59:81-90

Investigation of the conserved reentrant membrane helix in the monotopic phosphoglycosyl transferase superfamily supports key molecular interactions with polyprenol phosphate substrates

Authors: Entova, Sonya, Guan, Ziqiang, Imperiali, Barbara

Source: In Archives of Biochemistry and Biophysics 30 October 2019 675

Deploying Fluorescent Nucleoside Analogues for High‐Throughput Inhibitor Screening

Authors: Seebald, Leah, Madec, Amaël G. E., Imperiali, Barbara

Source: Chembiochem. 21(1-2):108-112

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100097863146.0x000001&indx=1&recIds=ETOCvdc_100097863146.0x000001

Application of a gut-immune co-culture system for the study of N-glycan-dependent host–pathogen interactions of Campylobacter jejuni

Authors: Zamora, Cristina Y, Ward, Elizabeth M, Kester, Jemila C, Chen, Wen Li Kelly, Velazquez, Jason G, Griffith, Linda G, Imperiali, Barbara

Source: Glycobiology. 30(6):374-381

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100109231141.0x000001&indx=1&recIds=ETOCvdc_100109231141.0x000001

Dual Glycosyltransferases from Campylobacter concisus Diverge from the Canonical Campylobacter N‑Linked Glycan Assembly Pathway.

Authors: Arbour, Christine A., Vuksanovic, Nemanja, Allen, Karen N., Imperiali, Barbara

Source: Biochemistry; 9/17/2024, Vol. 63 Issue 18, p2369-2379, 11p

Monotopic Membrane Proteins Join the Fold

Authors: Allen, Karen N., Entova, Sonya, Ray, Leah C., Imperiali, Barbara

Source: In Trends in Biochemical Sciences January 2019 44(1):7-20

Design, solid-phase synthesis and evaluation of enterobactin analogs for iron delivery into the human pathogen Campylobacter jejuni

Authors: Zamora, Cristina Y., Madec, Amaël G.E., Neumann, Wilma, Nolan, Elizabeth M., Imperiali, Barbara

Source: In Bioorganic & Medicinal Chemistry 15 October 2018 26(19):5314-5321

Stereochemical Divergence of Polyprenol Phosphate Glycosyltransferases

Authors: Eichler, Jerry, Imperiali, Barbara

Source: In Trends in Biochemical Sciences January 2018 43(1):10-17