Loss of IκB kinase β promotes myofibroblast transformation and senescence through activation of the ROS-TGFβ autocrine loop

Authors: Liang Chen, Zhimin Peng, Qinghang Meng, Maureen Mongan, Jingcai Wang, Maureen Sartor, Jing Chen, Liang Niu, Mario Medvedovic, Winston Kao, Ying Xia

Source: Protein & Cell, Vol 7, Iss 5, Pp 338-350 (2016)

Subject Terms: IkB kinase β (IKKβ), nuclear factor κB (NF-κB), transforming growth factors β (TGFβ), reactive oxygen species (ROS), myofibroblast, senescence, Cytology, QH573-671, Animal biochemistry, QP501-801

File Description: electronic resource

Relation: http://link.springer.com/article/10.1007/s13238-015-0241-6; https://doaj.org/toc/1674-800X; https://doaj.org/toc/1674-8018

Access URL: https://doaj.org/article/3ec46300fa9044e9b73b987e7366ed1b