Exploring the anti-EBV potential of suberoylanilide hydroxamic acid: Induction of apoptosis in infected cells through suppressing BART gene expression and inducing lytic infection

Authors: Liu, Yuxin, Wai, Aung Phyo, Zolzaya, Tumurgan, Iida, Yuichi, Okada, Shunpei, Iizasa, Hisashi, Yoshiyama, Hironori

Source: In Virology September 2024 597

A modulatory effect of L-arginine supplementation on anticancer effects of chemoimmunotherapy in colon cancer-bearing aged mice

Authors: Ishitobi, Kazunari, Kotani, Hitoshi, Iida, Yuichi, Taniura, Takahito, Notsu, Yoshitomo, Tajima, Yoshitsugu, Harada, Mamoru

Source: In International Immunopharmacology December 2022 113 Part A

A transchromosomic rat model with human chromosome 21 shows robust Down syndrome features

Authors: Kazuki, Yasuhiro, Gao, Feng J., Yamakawa, Miho, Hirabayashi, Masumi, Kazuki, Kanako, Kajitani, Naoyo, Miyagawa-Tomita, Sachiko, Abe, Satoshi, Sanbo, Makoto, Hara, Hiromasa, Kuniishi, Hiroshi, Ichisaka, Satoshi, Hata, Yoshio, Koshima, Moeka, Takayama, Haruka, Takehara, Shoko, Nakayama, Yuji, Hiratsuka, Masaharu, Iida, Yuichi, Matsukura, Satoko, Noda, Naohiro, Li, Yicong, Moyer, Anna J., Cheng, Bei, Singh, Nandini, Richtsmeier, Joan T., Oshimura, Mitsuo, Reeves, Roger H.

Source: American journal of human genetics. 109(2):328-344

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100180434063.0x000001&indx=1&recIds=ETOCvdc_100180434063.0x000001

An improved TK-NOG mouse as a novel platform for humanized liver that overcomes limitations in both male and female animals

Authors: Uehara, Shotaro, Higuchi, Yuichiro, Yoneda, Nao, Kawai, Kenji, Yamamoto, Masafumi, Kamimura, Hidetaka, Iida, Yuichi, Oshimura, Mitsuo, Kazuki, Yasuhiro, Yamazaki, Hiroshi, Hikita, Hayato, Takehara, Tetsuo, Suemizu, Hiroshi

Source: In Drug Metabolism and Pharmacokinetics February 2022 42

Protective role of cytoplasmic p21Cip1/Waf1 in apoptosis of CDK4/6 inhibitor‐induced senescence in breast cancer cells

Authors: Kartika, Irna D., Kotani, Hitoshi, Iida, Yuichi, Koyanagi, Akira, Tanino, Ryosuke, Harada, Mamoru

Source: Cancer medicine. 10(24):8988-8999

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100137116092.0x000001&indx=1&recIds=ETOCvdc_100137116092.0x000001

Immunogenic chemotherapy in two mouse colon cancer models

Authors: Taniura, Takahito, Iida, Yuichi, Kotani, Hitoshi, Ishitobi, Kazunari, Tajima, Yoshitsugu, Harada, Mamoru

Source: Cancer science. 111(10):3527-3539

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100109047640.0x000001&indx=1&recIds=ETOCvdc_100109047640.0x000001

Supplementation of l‐arginine boosts the therapeutic efficacy of anticancer chemoimmunotherapy

Authors: Satoh, Yusuke, Kotani, Hitoshi, Iida, Yuichi, Taniura, Takahito, Notsu, Yoshitomo, Harada, Mamoru

Source: Cancer science. 111(7):2248-2258

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100107422884.0x000001&indx=1&recIds=ETOCvdc_100107422884.0x000001

Pemetrexed sensitizes human lung cancer cells to cytotoxic immune cells

Authors: Okimoto, Tamio, Kotani, Hitoshi, Iida, Yuichi, Koyanagi, Akira, Tanino, Ryosuke, Tsubata, Yukari, Isobe, Takeshi, Harada, Mamoru

Source: Cancer science. 111(6):1910-1920

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100107422334.0x000001&indx=1&recIds=ETOCvdc_100107422334.0x000001

Therapeutic Senolysis of Axitinib-Induced Senescent Human Lung Cancer Cells.

Authors: Kotani, Hitoshi, Han, Wei, Iida, Yuichi, Tanino, Ryosuke, Katakawa, Kazuaki, Okimoto, Tamio, Tsubata, Yukari, Isobe, Takeshi, Harada, Mamoru

Source: Cancers; Aug2024, Vol. 16 Issue 16, p2782, 17p

Subject Terms: VASCULAR endothelial growth factors, BIOLOGICAL models, ADENOCARCINOMA, FLOW cytometry, PHOSPHORYLATION, RESEARCH funding, CELLULAR aging, ANTINEOPLASTIC agents, PROTEIN-tyrosine kinase inhibitors, APOPTOSIS, POLYMERASE chain reaction, XENOGRAFTS, DESCRIPTIVE statistics, CELL lines, MICE, GENE expression, REACTIVE oxygen species, MESSENGER RNA, CELL death, LUNG tumors, ANIMAL experimentation, MOLECULAR structure, CELL size, LUNG cancer, GLYCOSIDASES, CELL receptors, INTERLEUKINS, PHARMACODYNAMICS

Humanized liver TK-NOG mice with functional deletion of hepatic murine cytochrome P450s as a model for studying human drug metabolism.

Authors: Uehara, Shotaro¹ (AUTHOR), Iida, Yuichi^2,3 (AUTHOR), Ida-Tanaka, Miyuki¹ (AUTHOR), Goto, Motohito⁴ (AUTHOR), Kawai, Kenji⁵ (AUTHOR), Yamamoto, Masafumi⁶ (AUTHOR), Higuchi, Yuichiro¹ (AUTHOR), Ito, Satoshi⁷ (AUTHOR), Takahashi, Riichi⁴ (AUTHOR), Kamimura, Hidetaka^7,8 (AUTHOR), Ito, Mamoru¹ (AUTHOR), Yamazaki, Hiroshi⁹ (AUTHOR), Oshimura, Mitsuo² (AUTHOR), Kazuki, Yasuhiro^2,10 (AUTHOR), Suemizu, Hiroshi¹ (AUTHOR) suemizu@ciea.or.jp

Source: Scientific Reports. 9/1/2022, Vol. 12 Issue 1, p1-12. 12p.

Subject Terms: *MICROSOMES, *DRUG metabolism, *LIVER microsomes, *CYTOCHROME P-450, *MICE, *LIVER

Different sensitivities of senescent breast cancer cells to immune cell‐mediated cytotoxicity

Authors: Inao, Touko, Kotani, Hitoshi, Iida, Yuichi, Kartika, Irna Diyana, Okimoto, Tamio, Tanino, Ryosuke, Shiba, Eiichi, Harada, Mamoru

Source: Cancer science. 110(9):2690-2699

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100087646551.0x000001&indx=1&recIds=ETOCvdc_100087646551.0x000001

Protective roles of cytoplasmic p21Cip1/Waf1 in senolysis and ferroptosis of lung cancer cells

Authors: Koyanagi, Akira, Kotani, Hitoshi, Iida, Yuichi, Tanino, Ryosuke, Kartika, Irna D., Kishimoto, Koji, Harada, Mamoru

Source: Cell proliferation. 55(12)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100166968102.0x000001&indx=1&recIds=ETOCvdc_100166968102.0x000001

Hypoxia‐related carbonic anhydrase 9 induces serpinB9 expression in cancer cells and apoptosis in T cells via acidosis.

Authors: Harada, Mamoru, Kotani, Hitoshi, Iida, Yuichi, Tanino, Ryosuke, Minami, Takafumi, Komohara, Yoshihiro, Yoshikawa, Kazuhiro, Uemura, Hirotsugu

Source: Cancer Science; May2024, Vol. 115 Issue 5, p1405-1416, 12p

Senolysis of gemcitabine‐induced senescent human pancreatic cancer cells.

Authors: Hoque, Mohammad Mahbubul, Iida, Yuichi, Kotani, Hitoshi, Harada, Mamoru

Source: Cancer Reports; Apr2024, Vol. 7 Issue 4, p1-11, 11p

Contrasting effects of cyclophosphamide on anti‐CTL‐associated protein 4 blockade therapy in two mouse tumor models

Authors: Iida, Yuichi, Harashima, Nanae, Motoshima, Takanobu, Komohara, Yoshihiro, Eto, Masatoshi, Harada, Mamoru

Source: Cancer science. 108(10):1974-1984

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100097862065.0x000001&indx=1&recIds=ETOCvdc_100097862065.0x000001

Display device and control method

Human artificial chromosome (HAC) vector with a conditional centromere for correction of genetic deficiencies in human cells

Authors: Kim, Jung-Hyun, Kononenko, Artem, Erliandri, Indri, Kim, Tae-Aug, Nakano, Megumi, Iida, Yuichi, Barrett, J. Carl, Oshimura, Mitsuo, Masumoto, Hiroshi, Earnshaw, William C., Larionov, Vladimir, Kouprina, Natalay

Source: Proceedings of the National Academy of Sciences of the United States of America, 2011 Dec . 108(50), 20048-20053.

Access URL: https://www.jstor.org/stable/23060073

Display method and display apparatus

Multilayer ceramic substrate and method for producing the same

Display device and controlling method