Kallikrein-Related Peptidase 6 Contributes to Murine Intestinal Tumorigenesis Driven by a Mutant Adenomatous polyposis coli Gene.

Authors: Georgieva, Teodora G., Darmoul, Dalila, Chen, Hwudaurw, Cui, Haiyan, Rice, Photini F. S., Barton, Jennifer K., Besselsen, David G., Ignatenko, Natalia A.

Source: Cancers; Nov2024, Vol. 16 Issue 22, p3842, 26p

Subject Terms: RISK assessment, BIOLOGICAL models, INTESTINES, MITOGEN-activated protein kinases, PHOSPHORYLATION, RESEARCH funding, GENETIC engineering, OPTICAL coherence tomography, DESCRIPTIVE statistics, BLOOD coagulation factors, TUMOR suppressor genes, GENE expression, EPITHELIUM, MICE, MESSENGER RNA, IMMUNOHISTOCHEMISTRY, COLON (Anatomy), INTESTINAL tumors, PROTEOLYTIC enzymes, ANIMAL experimentation, GENETIC mutation, ADENOMATOUS polyposis coli, MOLECULAR biology, ALLELES, SMALL intestine, TRANSFORMING growth factors-beta, DISEASE risk factors

Synthesis and Structure‐Activity Relationships of N‐(4‐Benzamidino)‐Oxazolidinones: Potent and Selective Inhibitors of Kallikrein‐Related Peptidase 6

Authors: De Vita, Elena, Smits, Niels, Hurk, Helma, Beck, Elizabeth M., Hewitt, Joanne, Baillie, Gemma, Russell, Emily, Pannifer, Andrew, Hamon, Véronique, Morrison, Angus, McElroy, Stuart P., Jones, Philip, Ignatenko, Natalia A., Gunkel, Nikolas, Miller, Aubry K.

Source: ChemMedChem. 15(1):79-95

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100097872150.0x000001&indx=1&recIds=ETOCvdc_100097872150.0x000001

Specific microRNA–mRNA Regulatory Network of Colon Cancer Invasion Mediated by Tissue Kallikrein–Related Peptidase 6

Authors: Sells, Earlphia, Pandey, Ritu, Chen, Hwudaurw, Skovan, Bethany A., Cui, Haiyan, Ignatenko, Natalia A.

Source: In Neoplasia May 2017 19(5):396-411

FORMATION OF COGNITIVE-TECHNOLOGICAL COMPETENCE AS A MECHANISM OF REALISATION OF RATIONAL COMPONENT IN TRAINING UNDERGRADUATE STUDENTS.

Authors: Ignatenko, Natalia¹ ignatenkol707@ukr.net, Savenco, Victor² moosson@ukr.net, Kryskov, Andrii³ Kryskov.te@gmail.com, Habrusieva, Nataliia³ gabrusyeva@gmail.com, Tetiana, Remekh⁴ remehtatyana@gmail.com

Source: Journal of Education, Culture & Society. 2024, Vol. 15 Issue 1, p247-263. 17p.

Subject Terms: *UNDERGRADUATES, *COGNITIVE development, *HISTORY teachers, *MASTER'S degree, *TEACHER role

Geographic Terms: AMERICA

Detection of Enzyme Activity and Inhibition during Studies in Solution, In Vitro and In Vivo with CatalyCEST MRI

Authors: Sinharay, Sanhita, Randtke, Edward A., Howison, Christine M., Ignatenko, Natalia A., Pagel, Mark D.

Source: Molecular imaging and biology. 20(2):240-248

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100127752014.0x000001&indx=1&recIds=ETOCvdc_100127752014.0x000001

Recurrent horizontal transfer identifies mitochondrial positive selection in a transmissible cancer

Authors: Strakova, Andrea, Nicholls, Thomas J., Baez-Ortega, Adrian, Ní Leathlobhair, Máire, Sampson, Alexander T., Hughes, Katherine, Bolton, Isobelle A. G., Gori, Kevin, Wang, Jinhong, Airikkala-Otter, Ilona, Allen, Janice L., Allum, Karen M., Arnold, Clara L., Bansse-Issa, Leontine, Bhutia, Thinlay N., Bisson, Jocelyn L., Blank, Kelli, Briceño, Cristóbal, Castillo Domracheva, Artemio, Corrigan, Anne M., Cran, Hugh R., Crawford, Jane T., Cutter, Stephen M., Davis, Eric, de Castro, Karina F., De Nardi, Andrigo B., de Vos, Anna P., Delgadillo Keenan, Laura, Donelan, Edward M., Espinoza Huerta, Adela R., Faramade, Ibikunle A., Fazil, Mohammed, Fotopoulou, Eleni, Fruean, Skye N., Gallardo-Arrieta, Fanny, Glebova, Olga, Gouletsou, Pagona G., Häfelin Manrique, Rodrigo F., Henriques, Joaquim J. G. P., Horta, Rodrigo S., Ignatenko, Natalia, Kane, Yaghouba, King, Cathy, Koenig, Debbie, Krupa, Ada, Kruzeniski, Steven J., Lanza-Perea, Marta, Lazyan, Mihran, Lopez Quintana, Adriana M., Losfelt, Thibault, Marino, Gabriele, Martínez Castañeda, Simón, Martínez-López, Mayra F., Masuruli, Bedan M., Meyer, Michael, Migneco, Edward J., Nakanwagi, Berna, Neal, Karter B., Neunzig, Winifred, Nixon, Sally J., Ortega-Pacheco, Antonio, Pedraza-Ordoñez, Francisco, Peleteiro, Maria C., Polak, Katherine, Pye, Ruth J., Ramirez-Ante, Juan C., Reece, John F., Rojas Gutierrez, Jose, Sadia, Haleema, Schmeling, Sheila K., Shamanova, Olga, Sherlock, Alan G., Steenland-Smit, Audrey E., Svitich, Alla, Tapia Martínez, Lester J., Thoya Ngoka, Ismail, Torres, Cristian G., Tudor, Elizabeth M., van der Wel, Mirjam G., Vițălaru, Bogdan A., Vural, Sevil A., Walkinton, Oliver, Wehrle-Martinez, Alvaro S., Widdowson, Sophie A. E., Zvarich, Irina, Chinnery, Patrick F., Falkenberg, Maria, Gustafsson, Claes M., Murchison, Elizabeth P.

Source: Nature communications. 11(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100174593315.0x000001&indx=1&recIds=ETOCvdc_100174593315.0x000001

Digital image analysis using video microscopy of human-derived prostate cancer vs normal prostate organoids to assess migratory behavior on extracellular matrix proteins.

Authors: Marr, Kendra D., Ignatenko, Natalia A., Warfel, Noel A., Batai, Ken, Cress, Anne E., Pollock, Grant R., Wong, Ava C., Lee, Benjamin R.

Source: Frontiers in Oncology; 1/16/2023, Vol. 13, p01-04, 4p

Subject Terms: PROSTATE cancer, EXTRACELLULAR matrix proteins, VIDEO microscopy, IMAGE analysis, ORGANOIDS, PROSTATE

Caveolin-1-Mediated Expression and Secretion of Kallikrein 6 in Colon Cancer Cells

Authors: Henkhaus, Rebecca S., Roy, Upal Kunal Basu, Cavallo-Medved, Dora, Sloane, Bonnie F., Gerner, Eugene W., Ignatenko, Natalia A.

Source: In Neoplasia February 2008 10(2):140-148

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Kallikrein-Related Peptidase 6 (KLK6) as a Contributor toward an Aggressive Cancer Cell Phenotype: A Potential Role in Colon Cancer Peritoneal Metastasis.

Authors: Bouzid, Hayet, Soualmia, Feryel, Oikonomopoulou, Katerina, Soosaipillai, Antoninus, Walker, Francine, Louati, Khaoula, Lo Dico, Rea, Pocard, Marc, El Amri, Chahrazade, Ignatenko, Natalia A., Darmoul, Dalila

Source: Biomolecules (2218-273X); Jul2022, Vol. 12 Issue 7, pN.PAG-N.PAG, 22p

Subject Terms: PERITONEAL cancer, COLON cancer, EXTRACELLULAR matrix proteins, EXTRACELLULAR signal-regulated kinases, PEPTIDASE, METASTASIS

Molecular Biology of Cancer

Authors: MARTINEZ, JESSE D, PARKER, MICHELE TAYLOR, FULTZ, KIMBERLY E, IGNATENKO, NATALIA A, GERNER, EUGENE W

Source: Burger's Medicinal Chemistry and Drug Discovery. 2003, v. 5, p1-50.

Subject Terms: Gene therapy, Gene expression, Cell division, Growth factor receptors, Reactive oxygen species, Growth factors, DNA microarrays, Serine, Cyclooxygenases, Cancer, Cell adhesion, COX-2 inhibitors, Proteases, Gene mutation, Transforming growth factors, Genetic vectors, Carcinogens, DNA repair, Ornithine decarboxylase, DNA, Familial polyposis, Methylation, Genetic polymorphisms, DNA synthesis, Cancer prevention, Retinoblastoma, DNA damage, Phosphotransferases, Tumor suppressor genes, Neovascularization, Cancer treatment, Apoptosis, Oncogenes, Carcinogenesis, Purine nucleotides, Immortality, Immune response, Epigenetic inheritance, Transcription factors, Threonine, DNA mismatch repair, Molecular biology, Guanosine triphosphate, Protein-tyrosine kinase, Cyclins, Viruses, Cell proliferation, Tumor proteins, G proteins, Phosphatases, Genetic variation, Anticoagulants, Cell cycle

Cyclooxygenase-independent Induction of Apoptosis by Sulindac Sulfone Is Mediated by Polyamines in Colon Cancer

Authors: Babbar, Naveen ^{‡, §}, Ignatenko, Natalia A. ^{‡, ¶}, Casero, Robert A., Jr. ^∥, Gerner, Eugene W. ^{‡, §, ¶, **}

Source: In Journal of Biological Chemistry 28 November 2003 278(48):47762-47775

Regulation of the HIV1 long terminal repeat by mutant heat shock factor

Authors: Ignatenko, Natalia A, Gerner, Eugene W

Source: In Experimental Cell Research 2003 288(1):1-8

Dietary Putrescine Reduces the Intestinal Anticarcinogenic Activity of Sulindac in a Murine Model of Familial Adenomatous Polyposis.

Authors: Ignatenko, Natalia A.¹, Besselsen, David G.², Roy, Upal K. Basu³, Stringer, David E.⁴, Blohm-Mangone, Karen A.⁴, Padilla-Torres, Jose L.⁴, Guillen-R., Jose M.⁴, Gerner, Eugene W.^1,3

Source: Nutrition & Cancer. 2006, Vol. 56 Issue 2, p172-181. 10p. 1 Chart, 7 Graphs.

Subject Terms: *NONSTEROIDAL anti-inflammatory agents, *SULINDAC, *FAMILIAL diseases, *CANCER cells, *APOPTOSIS, *PUTRESCINE, *COLON (Anatomy)

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Chapter 2 - Polyamines in cancer

Authors: Paz, Edwin A. ^⁎, Garcia-Huidobro, Jenaro, Ignatenko, Natalia A.

Source: In Advances in Clinical Chemistry 2011 54:45-70

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