Pembrolizumab plus concurrent chemoradiotherapy versus placebo plus concurrent chemoradiotherapy in patients with locally advanced squamous cell carcinoma of the head and neck (KEYNOTE-412): a randomised, double-blind, phase 3 trial

Authors: Rischin, Danny, Hughes, Brett GM, Gao, Bo, McGrath, Margaret, Greil, Richard, Thurnher, Dietmar, Fuereder, Thorsten, Burian, Martin, Rottey, Sylvie, Machiels, Jean-Pascal, Clement, Paul M, Henry, Stéphanie, Deheneffe, Stéphanie, Vasconcelos Alves, Gustavo, Lima, Iane Pinto Figueiredo, Mourão Dias, Josiane, De Marchi, Pedro Rafael Martins, Mak, Milena Perez, Pereira de Santana Gomes, Andrea Juliana, Oliveira de Castro Junior, Dalvaro, Motta, Tatiane Cardoso, Agostinho Padoan, Monica Luciana, Victorina, Ana Paula, de Azevedo, Sergio Jobim, Siu, Lillian L, Brule, Stephanie, Hilton, John, Wang, Chang Shu, Bouganim, Nathaniel, Webster, Marc, Walker, John, Chua, Neil, Zambrano, Angela Regina, Quiroga Echeverri, Alicia, Niño Gomez, Oscar Mauricio, Ortiz, Carlos Alberto, Rojas, Luis, Cardona Zorilla, Andrés, Urrego Meléndez, Olga Marcela, Holečková, Petra Beran, Melichar, Bohuslav, Cvek, Jakub, Prausová, Jana, Vošmik, Milan, Delord, Jean-Pierre, Zasadny, Xavier, Geoffrois, Lionnel, Tao, Yungan, Pointreau, Yoann, Fietkau, Rainer, Haderlein, Marlen, Mueller, Andreas H, Schroeder, Ursula, Wollenberg, Barbara, Laban, Simon, Ivanyi, Philipp, Gruenwald, Viktor, Schafhausen, Philippe, Gutfeld, Orit, Gluck, Iris, Popovtzer, Aron, Meirovitz, Amichay, Billan, Salem, Brenner, Baruch, Limon, Dror, Licitra, Lisa, Perri, Francesco, Caponigro, Francesco, Violati, Martina, Ferrari, Daris, Nole, Franco, Bertolini, Federica, Livi, Lorenzo, Ghi, Maria Grazia, Imarisio, Ilaria, Tahara, Makoto, Homma, Akihiro, Ueda, Tsutomu, Asada, Yukinori, Yamazaki, Tomoko, Matsumoto, Koji, Fujii, Takashi, Ikeda, Sadakatsu, Takahashi, Shunji, Kinoshita, Takashi, Sasaki, Keita, Tsuji, Akihito, Ahn, Myung-Ju, Cho, Byoung Chul, Lee, Keun-Wook, Lee, Ki Hyeong, Choi, Moon Ki, Yun, Hwan Jung, Hendriks, Mathijs P, Oosting, Sjoukje F, Buter, Jan, Van Meerten, Esther, Graham, Jonathan, Kawecki, Andrzej, Debicka, Izabella, Maciejczyk, Adam, Pysz, Maciej, Filarska, Dorota, Hetnał, Marcin, Koralewski, Piotr, Wygoda, Andrzej, Składowski, Krzysztof, Talerczyk, Małgorzata, Berrocal Jaime, Alfonso, Pérez Segura, Pedro, Braña García, Irene, Basté Rotllan, Neus, Mesía Nin, Ricard, Taberna Sanz, Miren, Iglesias Docampo, Lara, Soria Rivas, Ainara, Rueda Domínguez, Antonio, Trigo Pérez, José Manuel, Hong, Ruey-Long, Li, Shau-Hsuan, Wang, Hung-Ming, Yen, Chia-Jui, Yang, Muh-Hwa, Chang, Yi-Fang, Liu, Yi-Chun, Lin, Jin-Ching, Ekenel, Meltem, Harputluoğlu, Hakan, Aksoy, Sercan, Özyilkan, Özgür, Bılıcı, Ahmet, Şendur, Mehmet Alı Nahıt, Arslan, Cagatay, Harrington, Kevin, Ramkumar, Shanmugasundaram, Gujral, Dorothy, Stewart, Simon, Powell, Melanie, Sibtain, Amen, Roques, Tom, Yip, Kent, Mirza, Arafat, Sivaramalingam, Muthiah, Belman, Neil D, Agarwala, Sanjiv, Anderson, Ian, Patel, Arpan, Maggiore, Ronald, Baumgart, Megan, Burtness, Barbara, Fidler, Mary Jo, Kaur, Varinder, Gaughan, Elizabeth, Worden, Francis, Rodriguez, Cristina P, Sukari, Ammar, Wong, Deborah, Yom, Sue, Walsh, William V, Fiorillo, Joseph A, Yorio, Jeffrey T, Obara, Grzegorz S, Alves, Gustavo ^g, Hughes, Brett G M ⁱ, Mesía, Ricard ^q, Taberna, Miren ^r, Waldron, John N ^s, Simon, Christian ^t, Grégoire, Vincent ^u, Harrington, Kevin J ^v, Swaby, Ramona F ^w, Zhang, Yayan ^w, Gumuscu, Burak ^w, Bidadi, Behzad ^w

Source: In The Lancet Oncology May 2024 25(5):572-587

Randomized phase 3 noninferiority trial of radiotherapy and cisplatin vs radiotherapy and cetuximab after docetaxel-cisplatin-fluorouracil induction chemotherapy in patients with locally advanced unresectable head and neck cancer

Authors: Hitt, Ricardo ^{a, ⁎}, Mesía, Ricard ^b, Lozano, Alicia ^c, Iglesias Docampo, Lara ^d, Grau, Juan J. ^e, Taberna, Miren ^f, Rubió-Casadevall, Jordi ^g, Martínez-Trufero, Javier ^h, Morillo, Edel del Barco ⁱ, García Girón, Carlos ^j, Vázquez Estévez, Sergio ^k, Cirauqui, Beatriz ^l, Cruz-Hernández, Juan Jesús ^m

Source: In Oral Oncology November 2022 134

Cetuximab, docetaxel, and cisplatin versus platinum, fluorouracil, and cetuximab as first-line treatment in patients with recurrent or metastatic head and neck squamous-cell carcinoma (GORTEC 2014-01 TPExtreme): a multicentre, open-label, randomised, phase 2 trial

Authors: BABA-HAMED, Nabil, BABIN, Emmanuel, BERA, Guillaume, BETRIAN-LAGARDE, Sarah, BLOT, Emmanuel, BOMPAS, Emmanuelle, BOREL, Christian, BOUCHEKOUA, Mohamed, BOZEC LE MOAL, Laurence, BRUYAS, Amandine, CALAIS, Gilles, CARPIUC, Ioana, CHAPET, Sophie, CHATELLIER, Thierry, CHAUFFERT, Bruno, CHELI, Sandrine, CLATOT, Florian, COJOCARASU, Oana, CORNELLY, Alexandre, COUTTE, Alexandre, DALLOZ, Pierre, DARLOY, Franck, DELHOMMEAU, Melissa, DE RAUCOURT, Dominique, DEBELLEIX, Christophe, DEBOURDEAU, Philippe, DILLIES-LEGRAIN, Anne Françoise, DO, Pascal, DUBOS-ARVIS, Catherine, DUCOULOMBIER, Agnès, EL KOURI, Claude, FALKOWSKI, Sabrina, FERRAND, François-Regis, GATINEAU, Michel, GERVAIS, Radj, GRAS, Louis, GUILLET, Pierre, HASBINI, Ali, HENAULT, Stéphane, HERRERA GOMEZ, Ruth Gabriela, HUGUET, Florence, KAMINSKY, Marie Christine, LAGRANGE, Aurélie, LAVAU-DENES, Sandrine, LE CAER, Hervé, LE FOLL, Christine, LEFEBVRE, Gautier, LINOT, Benjamin, LOPEZ, Qian, LORTHOLARY, Alain, MATIAS, Margarida, MAYACHE-BADIS, Lamia, MINNE, Floriane, MOLLON, Delphine, NEIDHARDT, Eve Marie, PAVILLET, Julien, PEYRADE, Frédéric, POINTREAU, Yohann, RAMEE, Jean-François, RAUCHE, Camille, RICHARD, Sandrine, RIZZO, Claudia, ROLLAND, Frédéric, SCHLURMANN, Friderike, STEFANI, Laetitia, TASSY, Louis, TAZI, Youssef, THERY, Jean-Christophe, TORTI EL ZEIN, Florida, TOULLEC, Clémence, TOURANI, Jean-Marc, TOUSSAINT, Philippe, VANBOCKSTAEL, Julie, VAULEON, Elodie, VIRET, Frédéric, WALER, Sabine, ATZPODIEN, Jens, BEHRENS, Caecilia, BUSCH, Chia Jung, DIETZ, Andreas, FELDMANN, Georg, FIETKAU, Rainer, GRANIZKA, Thordis, GREWE, Jürgen, GUNTINAS-LICHINUS, Orlando, HADLER-MIKESCH, Kristina, HAHN, Dennis, INHESTERN, Johanna, KELLNER, Karolin, KLINGHAMMER, Konrad, KRONENBERGER, Roland, LUEDTKE-HECKENKAMP, Kerstin, OCHSENREITHER, Sebastian, OTREMBA, Burkhard, PEUKER, Caroline Anna, PIRLICH, Markus, ROTHMANN, Frank, TOMETTEN, Mareike, WOHLFARTH, Sabine, ZEBRALLA, Veit, ZIPFEL, Matthias, ADANSA KLEIN, Juan Carlos, ARRAZUBI, Virginia, CABALLERO DAROQUI, Javier, CASTELO, Beatriz, CIRAUQUI CIRAUQUI, Beatriz, CRUZ HERNANDEZ, Juan Jesus, GALLEGO, Oscar, IGLESIAS DOCAMPO, Lara Carmen, LOPEZ POUSA, Antonio, MARTINEZ DEL PRADO, Maria, MARTINEZ-TRUFERO, Javier, PASTOR BORGONON, Miguel, PEREZ RUIZ, Elisabeth, QUIROGA GARCIA, Vanesa, RUBIO CASADEVALL, Jordi, VAZQUEZ FERNANDEZ, Silvia, Guigay, Joël ^{*, *}, Aupérin, Anne ^*, Fayette, Jérôme, Saada-Bouzid, Esma, Lafond, Cédrik, Taberna, Miren, Geoffrois, Lionnel, Martin, Laurent, Capitain, Olivier, Cupissol, Didier, Castanie, Hélène, Vansteene, Damien, Schafhausen, Philippe, Johnson, Alison, Even, Caroline, Sire, Christian, Duplomb, Sophie, Evrard, Camille, Delord, Jean-Pierre, Laguerre, Brigitte, Zanetta, Sylvie, Chevassus-Clément, Cécile, Fraslin, Aldéric, Louat, Fanny, Sinigaglia, Laura, Keilholz, Ulrich, Bourhis, Jean, Mesia, Ricard

Source: In The Lancet Oncology April 2021 22(4):463-475

Exploratory analysis of front-line therapies in REVEL: a randomised phase 3 study of ramucirumab plus docetaxel versus docetaxel for the treatment of stage IV non-small-cell lung cancer after disease progression on platinum-based therapy

Authors: Garon, Edward B., Scagliotti, Giorgio Vittorio, Gautschi, Oliver, Reck, Martin, Thomas, Michael, Iglesias Docampo, Lara, Kalofonos, Haralabos, Kim, Joo-Hang, Gans, Steven, Te Brustugun, Oddrje, Orlov, Sergey V., Cuyun Carter, Gebra, Zimmermann, Annamaria H., Oton, Ana B., Alexandris, Ekaterine, Lee, Pablo, Wolff, Katharina, Stefaniak, Victoria Jennifer, Socinski, Mark A., Pérol, Maurice

Source: In ESMO Open 2020 5(1)

Pembrolizumab alone or with chemotherapy versus cetuximab with chemotherapy for recurrent or metastatic squamous cell carcinoma of the head and neck (KEYNOTE-048): a randomised, open-label, phase 3 study

Authors: Lerzo, Guillermo, Tatangelo, Marcelo, Varela, Mirta, Zarba, Juan Jose, Boyer, Michael, Gan, Hui, Gao, Bo, Hughes, Brett, Mallesara, Girish, Rischin, Danny, Taylor, Anne, Burian, Martin, Fuereder, Thorsten, Greil, Richard, Barrios, Carlos Henrique, de Castro Junior, Dalvaro Oliveira, Castro, Gilberto, Franke, Fabio Andre, Girotto, Gustavo, Lima, Iane Pinto Figueiredo, Nicolau, Ulisses Ribaldo, Pinto, Gustavo Dix Junqueira, Santos, Lucas, Victorino, Ana-Paula, Chua, Neil, Couture, Felix, Gregg, Richard, Hansen, Aaron, Hilton, John, McCarthy, Joy, Soulieres, Denis, Ascui, Rodrigo, Gonzalez, Pablo, Villanueva, Luis, Torregroza, Marco, Zambrano, Angela, Holeckova, Petra, Kral, Zdenek, Melichar, Bohuslav, Prausova, Jana, Vosmik, Milan, Andersen, Maria, Gyldenkerne, Niels, Jurgens, Hannes, Putnik, Kadri, Reinikainen, Petri, Gruenwald, Viktor, Laban, Simon, Aravantinos, Gerasimos, Boukovinas, Ioannis, Georgoulias, Vassilis, Psyrri, Amanda, Kwong, Dora, Al-Farhat, Yousuf, Csoszi, Tibor, Erfan, Jozsef, Horvai, Geza, Landherr, Laszlo, Remenar, Eva, Ruzsa, Agnes, Szota, Judit, Billan, Salem, Gluck, Iris, Gutfeld, Orit, Popovtzer, Aron, Benasso, Marco, Bui, Simona, Ferrari, Vittorio, Licitra, Lisa, Nole, Franco, Fujii, Takashi, Fujimoto, Yasushi, Hanai, Nobuhiro, Hara, Hiroki, Matsumoto, Koji, Mitsugi, Kenji, Monden, Nobuya, Nakayama, Masahiro, Okami, Kenji, Oridate, Nobuhiko, Shiga, Kiyoto, Shimizu, Yasushi, Sugasawa, Masashi, Tahara, Makoto, Takahashi, Masanobu, Takahashi, Shunji, Tanaka, Kaoru, Ueda, Tsutomu, Yamaguchi, Hironori, Yamazaki, Tomoko, Yasumatsu, Ryuji, Yokota, Tomoya, Yoshizaki, Tomokazu, Kudaba, Iveta, Stara, Zinaida, Wan Ishak, Wan Zamaniah, Cheah, Soon Keat, Aguilar Ponce, Jose, Gonzalez Mendoza, Rene, Hernandez Hernandez, Carlos, Medina Soto, Francisco, Buter, Jan, Hoeben, Ann, Oosting, S., Suijkerbuijk, Karijn, Bratland, Aase, Brydoey, Marianne, Alvarez, Renzo, Mas, Luis, Caguioa, Priscilla, Querol, John, Regala, Eugenio Emmanuel, Tamayo, Maria Belen, Villegas, Ellie May, Kawecki, Andrzej, Karpenko, Andrey, Klochikhin, Arkadiy, Smolin, Alexey, Zarubenkov, Oleg, Goh, Boon Cher, Cohen, Graham, du Toit, Johanna, Jordaan, Christa, Landers, Gregory, Ruff, Paul, Szpak, Waldemar, Tabane, Neonyana, Brana, Irene, Iglesias Docampo, Lara, Lavernia, Javier, Mesia, Ricard, Abel, Edvard, Muratidu, Valentina, Nielsen, Niels, Cristina, Valerie, Rordorf, Tamara, Rothschild, Sacha, Hong, Ruey-Long, Wang, Hung-Ming, Yang, Muh-Hwa, Yeh, Su-Peng, Yen, Chia-Jui, Ngamphaiboon, Nuttapong, Soparattanapaisarn, Nopadol, Sriuranpong, Virote, Aksoy, Sercan, Cicin, Irfan, Ekenel, Meltem, Harputluoglu, Hakan, Ozyilkan, Ozgur, Harrington, Kevin, Agarwala, Sanjiv, Ali, Haythem, Alter, Robert, Anderson, Daniel, Bruce, Justine, Burtness, Barbara, Campbell, Nicholas, Conde, Miguel, Deeken, John, Edenfield, William, Feldman, Lawrence, Gaughan, Elizabeth, Goueli, Basem, Halmos, Balazs, Hegde, Upendra, Hunis, Brian, Jotte, Robert, Karnad, Anand, Khan, Saad, Laudi, Noel, Laux, Douglas, Martincic, Danko, McCune, Steven, McGaughey, Dean, Misiukiewicz, Krzysztof, Mulford, Deborah, Nadler, Eric, Neupane, Prakash, Nunnink, Johannes, Ohr, James, O'Malley, Meaghan, Patson, Brian, Paul, Doru, Popa, Elizabeta, Powell, Steven, Redman, Rebecca, Rella, Vincent, Rocha Lima, Chaio, Sivapiragasam, Abirami, Su, Yungpo, Sukari, Ammar, Wong, Stuart, Yilmaz, Emrullah, Yorio, Jeffrey, Harrington, Kevin J, Soulières, Denis, de Castro, Gilberto, Jr, Basté, Neus, Bratland, Åse, Hughes, Brett G M, Mesía, Ricard, González Mendoza, René, Roy, Ananya, Zhang, Yayan, Gumuscu, Burak, Cheng, Jonathan D, Jin, Fan

Source: In The Lancet 23-29 November 2019 394(10212):1915-1928

SEOM-GETNE-TTCC Clinical guideline thyroid cancer (2023).

Authors: Alonso-Gordoa, Teresa, Jimenez-Fonseca, Paula, Martinez-Trufero, Javier, Navarro, Miguel, Porras, Ignacio, Rubió-Casadevall, Jordi, Arregui Valles, Marta, Basté, Neus, Hernando, Jorge, Iglesias Docampo, Lara

Source: Clinical & Translational Oncology; Nov2024, Vol. 26 Issue 11, p2902-2916, 15p

TTCC-2019-02: real-world evidence of first-line cetuximab plus paclitaxel in recurrent or metastatic squamous cell carcinoma of the head and neck.

Authors: Rubió-Casadevall, Jordi, Cirauqui Cirauqui, Beatriz, Martinez Trufero, Javier, Plana Serrahima, Maria, García Castaño, Almudena, Carral Maseda, Alberto, Iglesias Docampo, Lara, Pérez Segura, Pedro, Ceballos Lenza, Isaac, Gutiérrez Calderón, Vanesa, Fuster Salvà, José, Pena Álvarez, Carolina, Hernandez, Irene, del Barco Morillo, Edel, Chaves Conde, Manuel, Martínez Galán, Joaquina, Durán Sánchez, Marisa, Quiroga, Vanesa, Ortega, Eugenia, Mesia, Ricard

Source: Frontiers in Oncology; 2023, p1-14, 14p

Subject Terms: SQUAMOUS cell carcinoma, CETUXIMAB, PACLITAXEL, NECK, FEBRILE neutropenia

Geographic Terms: SPAIN

Topical heparin as an effective and safe treatment for patients with capecitabine-induced hand-foot syndrome: results of a phase IIA trial supported by proteomic profiling of skin biopsies.

Authors: Rodríguez-Garzotto, Analia, Iglesias-Docampo, Lara, Díaz-García, C. Vanesa, Ruppen, Isabel, Ximénez-Embún, Pilar, Gómez, Carlos, Rodríguez-Peralto, J. Luis, de Frutos, Javier Ortiz, Lopez-Martin, Jose A., Grávalos, Cristina, Cortés-Funes, Hernán, Agulló-Ortuño, M. Teresa

Source: Therapeutic Advances in Medical Oncology; 3/26/2022, p1-12, 12p

Current approach and novel perspectives in nasopharyngeal carcinoma: the role of targeting proteasome dysregulation as a molecular landmark in nasopharyngeal cancer.

Authors: Yarza, Ramon, Bover, Mateo, Agulló-Ortuño, Maria Teresa, Iglesias-Docampo, Lara Carmen

Source: Journal of Experimental & Clinical Cancer Research (17569966); 6/21/2021, Vol. 40 Issue 1, p1-18, 18p

Subject Terms: NASOPHARYNX cancer, THERAPEUTICS, PROGNOSIS, MEMBRANE proteins, PROTEASOME inhibitors, TOOTH fractures

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CheckMate 141: 1‐Year Update and Subgroup Analysis of Nivolumab as First‐Line Therapy in Patients with Recurrent/Metastatic Head and Neck Cancer.

Authors: Gillison, Maura L., Blumenschein Jr., George, Fayette, Jerome, Guigay, Joel, Colevas, A. Dimitrios, Licitra, Lisa, Harrington, Kevin J., Kasper, Stefan, Vokes, Everett E., Even, Caroline, Worden, Francis, Saba, Nabil F., Iglesias Docampo, Lara Carmen, Haddad, Robert, Rordorf, Tamara, Kiyota, Naomi, Tahara, Makoto, Monga, Manish, Lynch, Mark, Li, Li

Source: Oncologist; Sep2018, Vol. 23 Issue 9, p1079-1082, 4p, 2 Diagrams, 4 Charts, 2 Graphs

Subject Terms: THERAPEUTIC use of monoclonal antibodies, PLATINUM compounds, CANCER relapse, HEAD tumors, METASTASIS, NECK tumors, SURVIVAL, RANDOMIZED controlled trials, TREATMENT effectiveness, DISEASE progression, PROGNOSIS, THERAPEUTICS

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