In-Silico Comparative Analysis of Egyptian SARS CoV-2 with Other Populations: a Phylogeny and Mutation Analysis

Authors: Sharawy, Lamis, Tantawy, Maha, Ahmed, Yara, Taha, Ahmed, Soliman, Omar, Ibrahim, Tamer M, El-Hadidi, Mohamed

Source: 2020 2nd Novel Intelligent and Leading Emerging Sciences Conference (NILES) Novel Intelligent and Leading Emerging Sciences Conference (NILES), 2020 2nd. :618-622 Oct, 2020

Relation: 2020 2nd Novel Intelligent and Leading Emerging Sciences Conference (NILES)

Synthesis and mechanistic insights of Coumarinyl-Indolinone hybrids as potent inhibitors of Leishmania major

Authors: Batran, Rasha Z. ^a, Ebaid, Manal S. ^{b, ⁎}, Nasralla, Sherry N. ^c, Son, Ninh The ^d, Ha, Nguyen Xuan ^e, Abdelsattar Ibrahim, Hoda Atef ^f, Alkabbani, Mahmoud Abdelrahman ^g, Kasai, Yusuke ^h, Imagawa, Hiroshi ^h, Al-Sanea, Mohammad M. ⁱ, Ibrahim, Tamer M. ^j, Elshamy, Abdelsamed I. ^{a, h}, Bekhit, Adnan A. ^{c, k}, Eldehna, Wagdy M. ^{j, l, ⁎⁎}, Sabt, Ahmed ^{a, ⁎⁎⁎}

Source: In European Journal of Medicinal Chemistry 15 April 2025 288

1, 5-Diaryl-1, 2, 4-triazole Ureas as New SLC-0111 Analogues Endowed with Dual Carbonic Anhydrase and VEGFR-2 Inhibitory Activities

Authors: Elsawi, Ahmed E., Elbadawi, Mostafa M., Nocentini, Alessio, Almahli, Hadia, Giovannuzzi, Simone, Shaldam, Moataz, Salem, Rofaida, Ibrahim, Tamer M., Abdel-Aziz, Hatem A., Supuran, Claudiu T.

Source: Journal of medicinal chemistry. 66(15):10558-10578

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN633630422&indx=1&recIds=ETOCRN633630422

Evaluation of novel pyrazol-4-yl pyridine derivatives possessing arylsulfonamide tethers as c-Jun N-terminal kinase (JNK) inhibitors in leukemia cells

Authors: Mersal, Karim I., Abdel-Maksoud, Mohammed S., Ali, Eslam M.H., Ammar, Usama M., Zaraei, Seyed-Omar, Haque, Md Mamunul, Das, Tanuza, Hassan, Noha F., Kim, Eunice EunKyeong, Lee, Jun-Seok, Park, HaJeung, Lee, Kwan Hyi, El-Gamal, Mohammed I., Kim, Hee-Kwon, Ibrahim, Tamer M., Oh, Chang-Hyun

Source: In European Journal of Medicinal Chemistry 5 December 2023 261

Discovery of indolinone-bearing benzenesulfonamides as new dual carbonic anhydrase and VEGFR-2 inhibitors possessing anticancer and pro-apoptotic properties

Authors: Saied, Samaa, Shaldam, Moataz, Elbadawi, Mostafa M., Giovannuzzi, Simone, Nocentini, Alessio, Almahli, Hadia, Salem, Rofaida, Ibrahim, Tamer M., Supuran, Claudiu T., Eldehna, Wagdy M.

Source: In European Journal of Medicinal Chemistry 5 November 2023 259

Design and synthesis of 6-arylpyridine-tethered sulfonamides as novel selective inhibitors of carbonic anhydrase IX with promising antitumor features toward the human colorectal cancer

Authors: Eldehna, Wagdy M., Mohammed, Eslam E., Al-Ansary, Ghada H., Berrino, Emanuela, Elbadawi, Mostafa M., Ibrahim, Tamer M., Jaballah, Maiy Y., Al-Rashood, Sara T., Binjubair, Faizah A., Celik, Meltem, Nocentini, Alessio, Elbarbry, Fawzy A., Sahin, Fikrettin, Abdel-Aziz, Hatem A., Supuran, Claudiu T., Fares, Mohamed

Source: In European Journal of Medicinal Chemistry 5 October 2023 258

In silico screening of SARS-CoV2 helicase using African natural products: Docking and molecular dynamics approaches

Authors: Knany, Hamada R., Elsabbagh, Sherif A., Shehata, Moustafa A., Eldehna, Wagdy M., Bekhit, Adnan A., Ibrahim, Tamer M.

Source: In Virology October 2023 587

Tetrahydrobenzo[h]quinoline derivatives as a novel chemotype for dual antileishmanial-antimalarial activity graced with antitubercular activity: Design, synthesis and biological evaluation

Authors: Ibrahim, Tamer M., Abada, Ghada, Dammann, Marcel, Maklad, Raed M., Eldehna, Wagdy M., Salem, Rofaida, Abdelaziz, Marwa M., El-domany, Ramadan A., Bekhit, Adnan A., Beockler, Frank M.

Source: In European Journal of Medicinal Chemistry 5 September 2023 257

Identification of novel piperazine-tethered phthalazines as selective CDK1 inhibitors endowed with in vitro anticancer activity toward the pancreatic cancer

Authors: Akl, Laila, Abd El-Hafeez, Amer Ali, Ibrahim, Tamer M., Salem, Rofaida, Marzouk, Hala Mohamed M., El-Domany, Ramadan A., Ghosh, Pradipta, Eldehna, Wagdy M., Abou-Seri, Sahar M.

Source: In European Journal of Medicinal Chemistry 5 December 2022 243

In-Silico targeting of SARS-CoV-2 NSP6 for drug and natural products repurposing

Authors: Abdelkader, Ahmed, Elzemrany, Amal A., El-Nadi, Mennatullah, Elsabbagh, Sherif A., Shehata, Moustafa A., Eldehna, Wagdy M., El-Hadidi, Mohamed, Ibrahim, Tamer M.

Source: Virology. 573:96-110

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100194981484.0x000001&indx=1&recIds=ETOCvdc_100194981484.0x000001

New pyrazolylpyrazoline derivatives as dual acting antimalarial-antileishamanial agents: synthesis, biological evaluation and molecular modelling simulations

Authors: Bekhit, Adnan A., Lodebo, Eskedar T., Hymete, Ariaya, Ragab, Hanan M., Bekhit, Salma A., Amagase, Kikuko, Batubara, Afnan, Abourehab, Mohammed A. S., Bekhit, Alaa El-Din A., Ibrahim, Tamer M.

Source: Journal of enzyme inhibition and medicinal chemistry. 37(1):2320-2333

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100168531525.0x000001&indx=1&recIds=ETOCvdc_100168531525.0x000001

Structure-guided approach on the role of substitution on amide-linked bipyrazoles and its effect on their anti-inflammatory activity

Authors: Domiati, Souraya A., Abd El Galil, Khaled H., Abourehab, Mohammed A. S., Ibrahim, Tamer M., Ragab, Hanan M.

Source: Journal of enzyme inhibition and medicinal chemistry. 37(1):2179-2190

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100168531418.0x000001&indx=1&recIds=ETOCvdc_100168531418.0x000001

Evaluating the structure-based virtual screening performance of SARS-CoV-2 main protease: A benchmarking approach and a multistage screening example against the wild-type and Omicron variants.

Authors: Galal, Noha, Beshay, Botros Y., Soliman, Omar, Ismail, Muhammad I., Abdelfadil, Mohamed, El-Hadidi, Mohamed, Arafa, Reem K., Ibrahim, Tamer M.

Source: PLoS ONE; 2/19/2025, Vol. 20 Issue 2, p1-27, 27p

Subject Terms: SARS-CoV-2 Omicron variant, VIRTUAL high-throughput screening (Drug development), VIRAL mutation, CHEMICAL libraries, SMALL molecules

Investigation of the anti-inflammatory and analgesic activities of promising pyrazole derivative

Authors: Bekhit, Adnan A., Nasralla, Sherry N., El-Agroudy, Eman J., Hamouda, Nahla, El-Fattah, Ahmed Abd, Bekhit, Salma A., Amagase, Kikuko, Ibrahim, Tamer M.

Source: In European Journal of Pharmaceutical Sciences 1 January 2022 168

Facilitating SARS CoV-2 RNA-Dependent RNA polymerase (RdRp) drug discovery by the aid of HCV NS5B palm subdomain binders: In silico approaches and benchmarking

Authors: Elghoneimy, Laila K., Ismail, Muhammad I., Boeckler, Frank M., Azzazy, Hassan M.E., Ibrahim, Tamer M.

Source: In Computers in Biology and Medicine July 2021 134

Development of novel benzofuran-based SLC-0111 analogs as selective cancer-associated carbonic anhydrase isoform IX inhibitors

Authors: Shaldam, Moataz, Eldehna, Wagdy M., Nocentini, Alessio, Elsayed, Zainab M., Ibrahim, Tamer M., Salem, Rofaida, El-Domany, Ramadan A., Capasso, Clemente, Abdel-Aziz, Hatem A., Supuran, Claudiu T.

Source: In European Journal of Medicinal Chemistry 15 April 2021 216

Targeting multiple conformations of SARS-CoV2 Papain-Like Protease for drug repositioning: An in-silico study

Authors: Ismail, Muhammad I., Ragab, Hanan M., Bekhit, Adnan A., Ibrahim, Tamer M.

Source: In Computers in Biology and Medicine April 2021 131

Synthesis and antimicrobial activity of some novel 1, 2-dihydro-[1, 2, 4]triazolo[1, 5-a]pyrimidines bearing amino acid moietyElectronic supplementary information (ESI) available. See DOI: 10.1039/d0ra08189b

Authors: Mohamed, Mounir A. A., Bekhit, Adnan A., Abd Allah, Omyma A., Kadry, Asmaa M., Ibrahim, Tamer M., Bekhit, Salma A., Amagase, Kikuko, El-Saghier, Ahmed M. M.

Source: RSC advances. 11(5):2905-2916

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100136886703.0x000001&indx=1&recIds=ETOCvdc_100136886703.0x000001

In silico identification of potential SARS COV-2 2′-O-methyltransferase inhibitor: fragment-based screening approach and MM-PBSA calculationsElectronic supplementary information (ESI) available. See DOI: 10.1039/d1ra01809d

Authors: El Hassab, Mahmoud A., Ibrahim, Tamer M., Shoun, Aly A., Al-Rashood, Sara T., Alkahtani, Hamad M., Alharbi, Amal, Eskandrani, Razan O., Eldehna, Wagdy M.

Source: RSC advances. 11(26):16026-16033

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100120412620.0x000001&indx=1&recIds=ETOCvdc_100120412620.0x000001

In silico identification of novel SARS-COV-2 2′-O-methyltransferase (nsp16) inhibitors: structure-based virtual screening, molecular dynamics simulation and MM-PBSA approaches

Authors: El Hassab, Mahmoud A., Ibrahim, Tamer M., Al-Rashood, Sara T., Alharbi, Amal, Eskandrani, Razan O., Eldehna, Wagdy M.

Source: Journal of enzyme inhibition and medicinal chemistry. 36(1):727-736

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100138859492.0x000001&indx=1&recIds=ETOCvdc_100138859492.0x000001