The PPAR-α selective agonist WY14643 improves lupus nephritis via the downregulation of the RORγT/STAT3 signaling pathway in MRL/lpr mice

Authors: Al-Mazroua, Haneen A. ^a, Nadeem, Ahmed ^a, Attia, Sabry M. ^a, Bakheet, Saleh A. ^a, Ahmad, Ajaz ^b, Ansari, Mushtaq A. ^a, Ibrahim, Khalid E. ^c, Alomar, Hatun A. ^a, Almutairi, Mohammed M. ^a, Algarzae, Norah K. ^d, Mahmoud, Mohamed A. ^a, Hussein, Marwa H. ^a, Ahmed, Omer M. ^a, Ahmad, Sheikh F. ^{a, ⁎}

Source: In International Immunopharmacology 3 January 2025 145

Evaluating the reproductive performance of Summan grouper, Epinephelus summana (Forsskal, 1775), in the Red Sea

Authors: Shamlol, Faozi S. ^a, Younis, Elsayed M. ^{a, ⁎⁎}, Gabr, Mohamed H. ^b, Amer, Shimaa A. ^{c, ⁎}, Davies, Simon J. ^d, Elnagar, Doaa M. ^a, Ibrahim, Khalid E. ^a, Alsaiad, Saad M. ^e

Source: In Heliyon 15 September 2024 10(17)

DNMT inhibitor, 5-aza-2′-deoxycytidine mitigates di(2-ethylhexyl) phthalate-induced aggravation of psoriasiform inflammation in mice via reduction in global DNA methylation in dermal and peripheral compartments

Authors: Alfardan, Ali S., Nadeem, Ahmed, Ahmad, Sheikh F., Al-Harbi, Naif O., Alqinyah, Mohammad, Attia, Sabry M., El-Sherbeeny, Ahmed M., Al-Harbi, Mohammad M., Al-Shabanah, Othman A., Ibrahim, Khalid E., Alhazzani, Khalid, Alanazi, Ahmed Z.

Source: In International Immunopharmacology 20 August 2024 137

Worsening of imiquimod-induced psoriasiform inflammation in mice by environmental pollutant, di-(2-ethylhexyl) phthalate through dysregulation in IL-17A and Nrf2/iNOS signaling in peripheral myeloid and CD4 + T cells

Authors: Alfardan, Ali S., Nadeem, Ahmed, Ahmad, Sheikh F., Al-Harbi, Naif O., Alqinyah, Mohammed, Attia, Sabry M., Sarawi, Wedad, Alanazi, Ahmed Z., Alhazzani, Khalid, Ibrahim, Khalid E.

Source: In International Immunopharmacology 5 January 2024 126

BALB/c and C57BL/6 mice differ in oxidant and antioxidant responses in innate and adaptive immune cells in an asthma model induced by cockroach allergens

Authors: Al-Kharashi, Layla A., Alqarni, Saleh A., Ahmad, Sheikh F., Al-Harbi, Naif O., Alsanea, Sary, Ibrahim, Khalid E., Algahtani, Mohammad M., Alhazzani, Khalid, Shazly, Gamal A., Al-Harbi, Mohammad M., Nadeem, Ahmed

Source: In International Immunopharmacology November 2023 124 Part B

Inhibition of non-receptor tyrosine kinase LCK partially mitigates mixed granulocytic airway inflammation in a murine model of asthma

Authors: Alqarni, Saleh A., Ahmad, Sheikh F., Alqahtani, Faleh, Al-Harbi, Naif O., Alshehri, Samiyah, Ibrahim, Khalid E., Alfardan, Ali S., Attia, Sabry M., Nadeem, Ahmed

Source: In International Immunopharmacology June 2023 119

CXCR3 antagonist NBI-74330 mitigates joint inflammation in Collagen-Induced arthritis model in DBA/1J mice

Authors: Ahmad, Sheikh F., Nadeem, Ahmed, Ansari, Mushtaq A., Bakheet, Saleh A., Alomar, Hatun A., Al-Mazroua, Haneen A., Ibrahim, Khalid E., Alshamrani, Ali A., Al-Hamamah, Mohammed A., Alfardan, Ali S., Attia, Sabry M.

Source: In International Immunopharmacology May 2023 118

Methylmercury chloride exposure exacerbates existing neurobehavioral and immune dysfunctions in the BTBR T+ Itpr3tf/J mouse model of autism

Authors: Al-Mazroua, Haneen A., Nadeem, Ahmed, Ansari, Mushtaq A., Attia, Sabry M., Albekairi, Thamer H., Bakheet, Saleh A., Alobaidi, Abdulelah F., Alhosaini, Khaled, Alqarni, Saleh A., Ibrahim, Khalid E., Alsaad, Abdulaziz M.S., Ahmad, Sheikh F.

Source: Immunology letters. 244:19-27

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100161602230.0x000001&indx=1&recIds=ETOCvdc_100161602230.0x000001

CCR1 antagonist J-113863 corrects the imbalance of pro- and anti-inflammatory cytokines in a SJL/J mouse model of relapsing-remitting multiple sclerosis

Authors: Ansari, Mushtaq A., Nadeem, Ahmed, Attia, Sabry M., Bakheet, Saleh A., Shahid, Mudassar, Rehman, Muneeb U., Alanazi, Mohammed M., Alhamed, Abdullah S., Ibrahim, Khalid E, Albekairi, Norah A, Ahmad, Sheikh F.

Source: In Immunobiology September 2022 227(5)

Acetyl-11-keto-β-boswellic acid improves clinical symptoms through modulation of Nrf2 and NF-κB pathways in SJL/J mouse model of experimental autoimmune encephalomyelitis

Authors: Nadeem, Ahmed, Ahmad, Sheikh F., Al-Harbi, Naif O., Sarawi, Wedad, Attia, Sabry M, Alanazi, Wael A., Ibrahim, Khalid E, Alsanea, Sary, Alqarni, Saleh A., Alfardan, Ali S., Bakheet, Saleh A.

Source: In International Immunopharmacology June 2022 107

CXCR2 antagonist SB332235 mitigates deficits in social behavior and dysregulation of Th1/Th22 and T regulatory cell-related transcription factor signaling in male BTBR T+ Itpr3tf/J mouse model of autism

Authors: Albekairi, Norah A., Nadeem, Ahmed, Ansari, Mushtaq A., Attia, Sabry M., Bakheet, Saleh A., Alanazi, Mohammed M., Alhamed, Abdullah S., Albekairi, Thamer H., Al-Mazroua, Haneen A., Ibrahim, Khalid E., Ahmad, Sheikh F.

Source: In Pharmacology, Biochemistry and Behavior June 2022 217

Lck signaling inhibition causes improvement in clinical features of psoriatic inflammation through reduction in inflammatory cytokines in CD4+ T cells in imiquimod mouse model

Authors: Al-Harbi, Naif O., Ahmad, Sheikh F., Almutairi, Mohammed, Alanazi, Ahmed Z., Ibrahim, Khalid E., Alqarni, Saleh A., Alqahtani, Faleh, Alhazzani, Khalid, Alharbi, Metab, Alasmari, Fawaz, Nadeem, Ahmed

Source: In Cellular Immunology June 2022 376

Role of ITK signaling in acute kidney injury in mice: Amelioration of acute kidney injury associated clinical parameters and attenuation of inflammatory transcription factor signaling in CD4+ T cells by ITK inhibition

Authors: Nadeem, Ahmed, Ahmad, Sheikh F., Al-Harbi, Naif O., Ibrahim, Khalid E., Sarawi, Wedad, Attia, Sabry M., Alasmari, Abdullah F., Alqarni, Saleh A., Alfradan, Ali S., Bakheet, Saleh A., Al-Harbi, Mohammad M.

Source: In International Immunopharmacology October 2021 99

Inhibition of interleukin-2-inducible T-cell kinase causes reduction in imiquimod-induced psoriasiform inflammation through reduction of Th17 cells and enhancement of Treg cells in mice

Authors: Nadeem, Ahmed, Ahmad, Sheikh F., Al-Harbi, Naif O., Ibrahim, Khalid E., Alqahtani, Faleh, As Sobeai, Homood M., Alotaibi, Moureq R.

Source: In Biochimie December 2020 179:146-156

Protective effect of lyophilized sapodilla (Manilkara zapota) fruit extract against CCl4-induced liver damage in rats

Authors: Alrashood, Sara T., Al-Asmari, Abdulrahman K., Alotaibi, Abdullah K., Manthiri, Rajamohamed A., Rafatullah, Syed, Hasanato, Rana M., Khan, Haseeb A., Ibrahim, Khalid E., Wali, Adil F.

Source: In Saudi Journal of Biological Sciences September 2020 27(9):2373-2379

Insight into the role of integrated carbohydrate polymers (starch, chitosan, and β-cyclodextrin) with mesoporous silica as carriers for ibuprofen drug; equilibrium and pharmacokinetic properties

Authors: Abukhadra, Mostafa R., Refay, Nermen M., Nadeem, Ahmed, El-Sherbeeny, Ahmed M., Ibrahim, Khalid E.

Source: In International Journal of Biological Macromolecules 1 August 2020 156:537-547

CXCR3 antagonist AMG487 inhibits glucocorticoid-induced tumor necrosis factor-receptor-related protein and inflammatory mediators in CD45 expressing cells in collagen-induced arthritis mouse model

Authors: Bakheet, Saleh A., Alrwashied, Bader S., Ansari, Mushtaq A., Nadeem, Ahmed, Attia, Sabry M., Assiri, Mohammed A., Alqahtani, Faleh, Ibrahim, Khalid E., Ahmad, Sheikh F.

Source: In International Immunopharmacology July 2020 84

Elevated expression of toll-like receptor 4 is associated with NADPH oxidase-induced oxidative stress in B cells of children with autism

Authors: Al-Harbi, Naif O., Nadeem, Ahmed, Ahmad, Sheikh F., AL-Ayadhi, Laila Y., Al-Harbi, Mohammad M., As Sobeai, Homood M., Ibrahim, Khalid E., Bakheet, Saleh A.

Source: In International Immunopharmacology July 2020 84

Therapeutic treatment with Ibrutinib attenuates imiquimod-induced psoriasis-like inflammation in mice through downregulation of oxidative and inflammatory mediators in neutrophils and dendritic cells

Authors: Al-Harbi, Naif O., Nadeem, Ahmed, Ahmad, Sheikh F., Bakheet, Saleh A., El-Sherbeeny, Ahmad M., Ibrahim, Khalid E., Alzahrani, Khalid S., Al-Harbi, Mohammed M., Mahmood, Hafiz M., Alqahtani, Faleh, Attia, Sabry M., Alotaibi, Moureq R.

Source: In European Journal of Pharmacology 15 June 2020 877

Blockade of interleukin-2-inducible T-cell kinase signaling attenuates acute lung injury in mice through adjustment of pulmonary Th17/Treg immune responses and reduction of oxidative stress

Authors: Nadeem, Ahmed, Al-Harbi, Naif O., Ahmad, Sheikh F., Al-Harbi, Mohammed M., Alhamed, Abdullah S., Alfardan, Ali S., Assiri, Mohammed A., Ibrahim, Khalid E., Albassam, Hussam

Source: In International Immunopharmacology June 2020 83