Staphylococcal superantigens evoke temporary and reversible T cell anergy, but fail to block the development of a bacterium specific cellular immune response

Authors: Heran Zhang, Ian R. Monk, Jessica Braverman, Claerwen M. Jones, Andrew G. Brooks, Timothy P. Stinear, Linda M. Wakim

Source: Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/c05a1fab140c4c649629a5df6a0761ef

Optimization of Reverse Transcription Loop-Mediated Isothermal Amplification for In Situ Detection of SARS-CoV‑2 in a Micro-Air-Filtration Device Format

Authors: Jacob Fry, Jean Y. H. Lee, Julie L. McAuley, Jessica L. Porter, Ian R. Monk, Samuel T. Martin, David J. Collins, Gregory J. Barbante, Nicholas J. Fitzgerald, Timothy P. Stinear

Source: ACS Omega, Vol 9, Iss 39, Pp 40832-40840 (2024)

Subject Terms: Chemistry, QD1-999

File Description: electronic resource

Relation: https://doaj.org/toc/2470-1343

Access URL: https://doaj.org/article/d450b3169bef4deb8b65be3fa933a452

Emergence and clonal expansion of a qacA-harbouring sequence type 45 lineage of methicillin-resistant Staphylococcus aureus

Authors: Yi Nong, Eike Steinig, Georgina L. Pollock, George Taiaroa, Glen P. Carter, Ian R. Monk, Stanley Pang, Denise A. Daley, Geoffrey W. Coombs, Brian M. Forde, Patrick N. A. Harris, Norelle L. Sherry, Benjamin P. Howden, Shivani Pasricha, Sarah L. Baines, Deborah A. Williamson

Source: Communications Biology, Vol 7, Iss 1, Pp 1-10 (2024)

Subject Terms: Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/2399-3642

Access URL: https://doaj.org/article/d738cf3544a04aedbcf99c1a4ea67914

Polyclonal but not monoclonal circulating memory CD4+ T cells attenuate the severity of Staphylococcus aureus bacteremia

Authors: Jessica Braverman, Ian R. Monk, Heran Zhang, Timothy P. Stinear, Linda M. Wakim

Source: Frontiers in Immunology, Vol 15 (2024)

Subject Terms: Staphylococcus aureus bacteremia, memory CD4+ T lymphocytes, polyclonal T cells, tissue-resident CD4+ T cells, circulating memory T-cell subsets, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2024.1417220/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/b4feca047c2643668ace208eafdda409

The two-component system WalKR provides an essential link between cell wall homeostasis and DNA replication in Staphylococcus aureus

Authors: Liam K. R. Sharkey, Romain Guerillot, Calum J. Walsh, Adrianna M. Turner, Jean Y. H. Lee, Stephanie L. Neville, Stephan Klatt, Sarah L. Baines, Sacha J. Pidot, Fernando J. Rossello, Torsten Seemann, Hamish E. G. McWilliam, Ellie Cho, Glen P. Carter, Benjamin P. Howden, Christopher A. McDevitt, Abderrahman Hachani, Timothy P. Stinear, Ian R. Monk

Source: mBio, Vol 14, Iss 6 (2023)

Subject Terms: Staphylococcus aureus, two-component regulatory systems, regulation of gene expression, essential genes, split luciferase, ChIP-seq, Microbiology, QR1-502

File Description: electronic resource

Relation: https://doaj.org/toc/2150-7511

Access URL: https://doaj.org/article/b925679724c74489887fb31d58cddb66

RNase III-CLASH of multi-drug resistant Staphylococcus aureus reveals a regulatory mRNA 3′UTR required for intermediate vancomycin resistance

Authors: Daniel G. Mediati, Julia L. Wong, Wei Gao, Stuart McKellar, Chi Nam Ignatius Pang, Sylvania Wu, Winton Wu, Brandon Sy, Ian R. Monk, Joanna M. Biazik, Marc R. Wilkins, Benjamin P. Howden, Timothy P. Stinear, Sander Granneman, Jai J. Tree

Source: Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/d679ff7794784a6c999945fa7bd9395e

Staphylococcus aureus stimulates neutrophil itaconate production that suppresses the oxidative burst

Authors: Kira L. Tomlinson, Sebastián A. Riquelme, Swikrity Upadhyay Baskota, Marija Drikic, Ian R. Monk, Timothy P. Stinear, Ian A. Lewis, Alice S. Prince

Source: Cell Reports, Vol 42, Iss 2, Pp 112064- (2023)

Subject Terms: CP: Immunology, CP: Microbiology, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S221112472300075X; https://doaj.org/toc/2211-1247

Access URL: https://doaj.org/article/767b8e41e2d14568853587d3c6c14abe

Zinc-binding to the cytoplasmic PAS domain regulates the essential WalK histidine kinase of Staphylococcus aureus

Authors: Ian R. Monk, Nausad Shaikh, Stephanie L. Begg, Mike Gajdiss, Liam K. R. Sharkey, Jean Y. H. Lee, Sacha J. Pidot, Torsten Seemann, Michael Kuiper, Brit Winnen, Rikki Hvorup, Brett M. Collins, Gabriele Bierbaum, Saumya R. Udagedara, Jacqueline R. Morey, Neha Pulyani, Benjamin P. Howden, Megan J. Maher, Christopher A. McDevitt, Glenn F. King, Timothy P. Stinear

Source: Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/8c79c77e7e1c43c2b593eb5939e70c11

Publisher Correction: RNase III-CLASH of multi-drug resistant Staphylococcus aureus reveals a regulatory mRNA 3′UTR required for intermediate vancomycin resistance

Authors: Daniel G. Mediati, Julia L. Wong, Wei Gao, Stuart McKellar, Chi Nam Ignatius Pang, Sylvania Wu, Winton Wu, Brandon Sy, Ian R. Monk, Joanna M. Biazik, Marc R. Wilkins, Benjamin P. Howden, Timothy P. Stinear, Sander Granneman, Jai J. Tree

Source: Nature Communications, Vol 13, Iss 1, Pp 1-1 (2022)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/54fa913078284d69af4dba8037a9a965

Comprehensive Genomic Investigation of Adaptive Mutations Driving the Low-Level Oxacillin Resistance Phenotype in Staphylococcus aureus

Authors: Stefano G. Giulieri, Romain Guérillot, Jason C. Kwong, Ian R. Monk, Ashleigh S. Hayes, Diane Daniel, Sarah Baines, Norelle L. Sherry, Natasha E. Holmes, Peter Ward, Wei Gao, Torsten Seemann, Timothy P. Stinear, Benjamin P. Howden

Source: mBio, Vol 11, Iss 6 (2020)

Subject Terms: Staphylococcus aureus, antibiotic resistance, β-lactams, genomics, Microbiology, QR1-502

File Description: electronic resource

Relation: https://doaj.org/toc/2150-7511

Access URL: https://doaj.org/article/16e4fb535fb74b31acb798bc483a9ccc

Comparative Transcriptomic and Functional Assessments of Linezolid-Responsive Small RNA Genes in Staphylococcus aureus

Authors: Wei Gao, Romain Guérillot, Ya Hsun Lin, Jai Tree, Marie Beaume, Patrice François, Ian R. Monk, Torsten Seemann, Jacques Schrenzel, Benjamin P. Howden, Timothy P. Stinear

Source: mSystems, Vol 5, Iss 1 (2020)

Subject Terms: RNA sequencing, Staphylococcus aureus, mutagenesis, postantibiotic effects, sRNA, transcriptome, Microbiology, QR1-502

File Description: electronic resource

Relation: https://doaj.org/toc/2379-5077

Access URL: https://doaj.org/article/9f94d3d36bc34a64a0306ea8844d02e0

Comparative Transcriptomic and Functional Assessments of Linezolid-Responsive Small RNA Genes in Staphylococcus aureus

Authors: Wei Gao, Romain Guérillot, Ya Hsun Lin, Jai Tree, Marie Beaume, Patrice François, Ian R. Monk, Torsten Seemann, Jacques Schrenzel, Benjamin P. Howden, Timothy P. Stinear

Source: mSystems, Vol 5, Iss 1 (2020)

Subject Terms: RNA sequencing, Staphylococcus aureus, mutagenesis, postantibiotic effects, sRNA, transcriptome, Microbiology, QR1-502

File Description: electronic resource

Relation: https://doaj.org/toc/2379-5077

Access URL: https://doaj.org/article/506b8e22dd4d4768a57f076c390bc272

Mining the Methylome Reveals Extensive Diversity in Staphylococcus epidermidis Restriction Modification

Authors: Jean Y. H. Lee, Glen P. Carter, Sacha J. Pidot, Romain Guérillot, Torsten Seemann, Anders Gonçalves da Silva, Timothy J. Foster, Benjamin P. Howden, Timothy P. Stinear, Ian R. Monk

Source: mBio, Vol 10, Iss 6 (2019)

Subject Terms: DNA methylation, Staphylococcus aureus, coagulase-negative staphylococci, generalized transduction, genetic manipulation, genome analysis, Microbiology, QR1-502

File Description: electronic resource

Relation: https://doaj.org/toc/2150-7511

Access URL: https://doaj.org/article/e3d32570b9ae423490b78ed214e1e8af

Bystander Activation of Pulmonary Trm Cells Attenuates the Severity of Bacterial Pneumonia by Enhancing Neutrophil Recruitment

Authors: Chenghao Ge, Ian R. Monk, Angela Pizzolla, Nancy Wang, James G. Bedford, Timothy P. Stinear, Glen P. Westall, Linda M. Wakim

Source: Cell Reports, Vol 29, Iss 13, Pp 4236-4244.e3 (2019)

Subject Terms: Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211124719316031; https://doaj.org/toc/2211-1247

Access URL: https://doaj.org/article/5eaaae78bad144c18a7ed28f4a9cdc08

Genomewide Profiling of the Enterococcus faecalis Transcriptional Response to Teixobactin Reveals CroRS as an Essential Regulator of Antimicrobial Tolerance

Authors: Rachel L. Darnell, Melanie K. Knottenbelt, Francesca O. Todd Rose, Ian R. Monk, Timothy P. Stinear, Gregory M. Cook

Source: mSphere, Vol 4, Iss 3 (2019)

Subject Terms: CroRS, Enterococcus, RNA sequencing, teixobactin, antimicrobial resistance, antimicrobial tolerance, Microbiology, QR1-502

File Description: electronic resource

Relation: https://doaj.org/toc/2379-5042

Access URL: https://doaj.org/article/c50567fb76cb42369d772605e2894761

Correspondence: Spontaneous secondary mutations confound analysis of the essential two-component system WalKR in Staphylococcus aureus

Authors: Ian R. Monk, Benjamin P. Howden, Torsten Seemann, Timothy P. Stinear

Source: Nature Communications, Vol 8, Iss 1, Pp 1-4 (2017)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/ba9d4524e0dd4cfb8d1d0fa9813cf7e8

YycH and YycI Regulate Expression of Staphylococcus aureus Autolysins by Activation of WalRK Phosphorylation

Authors: Mike Gajdiss, Ian R. Monk, Ute Bertsche, Janina Kienemund, Tanja Funk, Alina Dietrich, Michael Hort, Esther Sib, Timothy P. Stinear, Gabriele Bierbaum

Source: Microorganisms, Vol 8, Iss 6, p 870 (2020)

Subject Terms: WalK, WalR, two-component regulatory system, Staphylococcus aureus, YycH, YycI, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.mdpi.com/2076-2607/8/6/870; https://doaj.org/toc/2076-2607

Access URL: https://doaj.org/article/c2b6105d08294a348f125df64b053a65

Modelling staphylococcal pneumonia in a human 3D lung tissue model system delineates toxin-mediated pathology

Authors: Srikanth Mairpady Shambat, Puran Chen, Anh Thu Nguyen Hoang, Helena Bergsten, Francois Vandenesch, Nikolai Siemens, Gerard Lina, Ian R. Monk, Timothy J. Foster, Gayathri Arakere, Mattias Svensson, Anna Norrby-Teglund

Source: Disease Models & Mechanisms, Vol 8, Iss 11, Pp 1413-1425 (2015)

Subject Terms: Staphylococcus aureus, Pneumonia, 3D lung tissue model, Medicine, Pathology, RB1-214

File Description: electronic resource

Relation: http://dmm.biologists.org/content/8/11/1413; https://doaj.org/toc/1754-8411; https://doaj.org/toc/1754-8403

Access URL: https://doaj.org/article/1e8b12e343ab45eda34a7ca58f733b34

Genomic analysis of ST88 community-acquired methicillin resistant Staphylococcus aureus in Ghana

Authors: Grace Kpeli, Andrew H. Buultjens, Stefano Giulieri, Evelyn Owusu-Mireku, Samuel Y. Aboagye, Sarah L. Baines, Torsten Seemann, Dieter Bulach, Anders Gonçalves da Silva, Ian R. Monk, Benjamin P. Howden, Gerd Pluschke, Dorothy Yeboah-Manu, Timothy Stinear

Source: PeerJ, Vol 5, p e3047 (2017)

Subject Terms: Staphylococcus aureus, Whole genome sequencing, MRSA, ST88, Comparative genomics, Phylogeography, Medicine, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://peerj.com/articles/3047.pdf; https://peerj.com/articles/3047/; https://doaj.org/toc/2167-8359

Access URL: https://doaj.org/article/c41d1e13eaad41e9b10ff1c8dabbfb93

Evolutionary origins of the emergent ST796 clone of vancomycin resistant Enterococcus faecium

Authors: Andrew H. Buultjens, Margaret M.C. Lam, Susan Ballard, Ian R. Monk, Andrew A. Mahony, Elizabeth A. Grabsch, M. Lindsay Grayson, Stanley Pang, Geoffrey W. Coombs, J. Owen Robinson, Torsten Seemann, Paul D.R. Johnson, Benjamin P. Howden, Timothy P. Stinear

Source: PeerJ, Vol 5, p e2916 (2017)

Subject Terms: Enterococcus faecium, Vancomycin resistant, Genome sequence, PacBio, Evolution, Hospital adapted, Medicine, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://peerj.com/articles/2916.pdf; https://peerj.com/articles/2916/; https://doaj.org/toc/2167-8359

Access URL: https://doaj.org/article/992c08923e2840528332384c998a1844