Polyvalent Glycomimetic-Gold Nanoparticles Revealing Critical Roles of Glycan Display on Multivalent Lectin–Glycan Interaction Biophysics and Antiviral Properties

Authors: Xinyu Ning, Darshita Budhadev, Sara Pollastri, Inga Nehlmeier, Amy Kempf, Iain Manfield, W. Bruce Turnbull, Stefan Pöhlmann, Anna Bernardi, Xin Li, Yuan Guo, Dejian Zhou

Source: JACS Au, Vol 4, Iss 8, Pp 3295-3309 (2024)

Subject Terms: Chemistry, QD1-999

File Description: electronic resource

Relation: https://doaj.org/toc/2691-3704

Access URL: https://doaj.org/article/757f82838ccf4e62a5f84306bc3cb42c

The Mutagenic Plasticity of the Cholera Toxin B-Subunit Surface Residues: Stability and Affinity

Authors: Cheuk W. Au, Iain Manfield, Michael E. Webb, Emanuele Paci, W. Bruce Turnbull, James F. Ross

Source: Toxins, Vol 16, Iss 3, p 133 (2024)

Subject Terms: cholera toxin B-subunit, CTB, GM1 ganglioside, melting temperature, dissociation constant, Rosetta, Medicine

File Description: electronic resource

Relation: https://www.mdpi.com/2072-6651/16/3/133; https://doaj.org/toc/2072-6651

Access URL: https://doaj.org/article/2d51501d3fa340d8907c7ff8ace9c1e9

TRPA1–FGFR2 binding event is a regulatory oncogenic driver modulated by miRNA-142-3p

Authors: Jonathan Berrout, Eleni Kyriakopoulou, Lavanya Moparthi, Alexandra S. Hogea, Liza Berrout, Cristina Ivan, Mihaela Lorger, John Boyle, Chris Peers, Stephen Muench, Jacobo Elies Gomez, Xin Hu, Carolyn Hurst, Thomas Hall, Sujanitha Umamaheswaran, Laura Wesley, Mihai Gagea, Michael Shires, Iain Manfield, Margaret A. Knowles, Simon Davies, Klaus Suhling, Yurema Teijeiro Gonzalez, Neil Carragher, Kenneth Macleod, N. Joan Abbott, George A. Calin, Nikita Gamper, Peter M. Zygmunt, Zahra Timsah

Source: Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/33513ba93d3143cf9c9bd5f381eb5965

Affimer proteins are versatile and renewable affinity reagents

Authors: Christian Tiede, Robert Bedford, Sophie J Heseltine, Gina Smith, Imeshi Wijetunga, Rebecca Ross, Danah AlQallaf, Ashley PE Roberts, Alexander Balls, Alistair Curd, Ruth E Hughes, Heather Martin, Sarah R Needham, Laura C Zanetti-Domingues, Yashar Sadigh, Thomas P Peacock, Anna A Tang, Naomi Gibson, Hannah Kyle, Geoffrey W Platt, Nicola Ingram, Thomas Taylor, Louise P Coletta, Iain Manfield, Margaret Knowles, Sandra Bell, Filomena Esteves, Azhar Maqbool, Raj K Prasad, Mark Drinkhill, Robin S Bon, Vikesh Patel, Sarah A Goodchild, Marisa Martin-Fernandez, Ray J Owens, Joanne E Nettleship, Michael E Webb, Michael Harrison, Jonathan D Lippiat, Sreenivasan Ponnambalam, Michelle Peckham, Alastair Smith, Paul Ko Ferrigno, Matt Johnson, Michael J McPherson, Darren Charles Tomlinson

Source: eLife, Vol 6 (2017)

Subject Terms: Affimer, antibody, assay, Medicine, Science, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://elifesciences.org/articles/24903; https://doaj.org/toc/2050-084X

Access URL: https://doaj.org/article/703d31dbc0f14e0190b7ae2c2e80be55