Primary urethral adenocarcinoma harbors recurrent KRAS and EGFR alterations

Authors: Zhao, Ting, Iafrate, A. John, Wu, Chin-Lee ^⁎

Source: In Human Pathology March 2025 157

Ongoing evolution of SARS-CoV-2 drives escape from mRNA vaccine-induced humoral immunity

Authors: Roederer, Alex L. ¹, Cao, Yi ¹, St. Denis, Kerri ¹, Sheehan, Maegan L. ¹, Li, Chia Jung ¹, Lam, Evan C. ¹, Gregory, David J. ^{2, 3}, Poznansky, Mark C. ^{2, 4}, Iafrate, A. John ⁵, Canaday, David H. ^{6, 7}, Gravenstein, Stefan ^{8, 9, 10}, Garcia-Beltran, Wilfredo F. ^{1, 5}, Balazs, Alejandro B. ^{1, 11, ∗}

Source: In Cell Reports Medicine 17 December 2024 5(12)

Detection of EWSR1 fusions in CCOC by targeted RNA-seq

Authors: Rivera, Camron M., Faquin, William C, Thierauf, Julia, Afrogheh, Amir H., Jaquinet, Alexandre, Iafrate, A. John, Rivera, Miguel N., Troulis, Maria J.

Source: In Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology August 2022 134(2):240-244

Response to Severe Acute Respiratory Syndrome Coronavirus 2 Initial Series and Additional Dose Vaccine in Patients With Predominant Antibody Deficiency

Authors: Barmettler, Sara, DiGiacomo, Daniel V., Yang, Nancy J., Lam, Tiffany, Naranbhai, Vivek, Dighe, Anand S., Burke, Kristin E., Blumenthal, Kimberly G., Ling, Morris, Hesterberg, Paul E., Saff, Rebecca R., MacLean, James, Ofoman, Onosereme, Berrios, Cristhian, St Denis, Kerri J., Lam, Evan C., Gregory, David, Iafrate, Anthony John, Poznansky, Mark, Lee, Hang, Balazs, Alejandro, Pillai, Shiv, Farmer, Jocelyn R.

Source: In The Journal of Allergy and Clinical Immunology: In Practice June 2022 10(6):1622-1634

T cell reactivity to the SARS-CoV-2 Omicron variant is preserved in most but not all individuals

Authors: Naranbhai, Vivek, Nathan, Anusha, Kaseke, Clarety, Berrios, Cristhian, Khatri, Ashok, Choi, Shawn, Getz, Matthew A., Tano-Menka, Rhoda, Ofoman, Onosereme, Gayton, Alton, Senjobe, Fernando, Zhao, Zezhou, St Denis, Kerri J., Lam, Evan C., Carrington, Mary, Garcia-Beltran, Wilfredo F., Balazs, Alejandro B., Walker, Bruce D., Iafrate, A. John, Gaiha, Gaurav D.

Source: In Cell 17 March 2022 185(6):1041-1051

t(4;12)(q12;p13) ETV6-rearranged AML without eosinophilia does not involve PDGFRA: relevance for imatinib insensitivity

Authors: Mueller, Sarah B., Dal Cin, Paola, Le, Long P., Dias-Santagata, Dora, Lennerz, Jochen K., Iafrate, A. John, Marble, Hetal Desai, Brunner, Andrew M., Weinstock, Matthew J., Luskin, Marlise R., De Angelo, Daniel J., Stone, Richard M., Nardi, Valentina ^*

Source: In Blood Advances 8 February 2022 6(3):818-827

mRNA-based COVID-19 vaccine boosters induce neutralizing immunity against SARS-CoV-2 Omicron variant

Authors: Garcia-Beltran, Wilfredo F., St. Denis, Kerri J., Hoelzemer, Angelique, Lam, Evan C., Nitido, Adam D., Sheehan, Maegan L., Berrios, Cristhian, Ofoman, Onosereme, Chang, Christina C., Hauser, Blake M., Feldman, Jared, Roederer, Alex L., Gregory, David J., Poznansky, Mark C., Schmidt, Aaron G., Iafrate, A. John, Naranbhai, Vivek, Balazs, Alejandro B.

Source: In Cell 3 February 2022 185(3):457-466

Structure-guided T cell vaccine design for SARS-CoV-2 variants and sarbecoviruses

Authors: Nathan, Anusha, Rossin, Elizabeth J., Kaseke, Clarety, Park, Ryan J., Khatri, Ashok, Koundakjian, Dylan, Urbach, Jonathan M., Singh, Nishant K., Bashirova, Arman, Tano-Menka, Rhoda, Senjobe, Fernando, Waring, Michael T., Piechocka-Trocha, Alicja, Garcia-Beltran, Wilfredo F., Iafrate, A. John, Naranbhai, Vivek, Carrington, Mary, Walker, Bruce D., Gaiha, Gaurav D.

Source: In Cell 19 August 2021 184(17):4401-4413

Nanopore Flongle Sequencing as a Rapid, Single-Specimen Clinical Test for Fusion Detection

Authors: Jeck, William R., Iafrate, A. John, Nardi, Valentina

Source: In The Journal of Molecular Diagnostics May 2021 23(5):630-636

Multiple SARS-CoV-2 variants escape neutralization by vaccine-induced humoral immunity

Authors: Garcia-Beltran, Wilfredo F., Lam, Evan C., St. Denis, Kerri, Nitido, Adam D., Garcia, Zeidy H., Hauser, Blake M., Feldman, Jared, Pavlovic, Maia N., Gregory, David J., Poznansky, Mark C., Sigal, Alex, Schmidt, Aaron G., Iafrate, A. John, Naranbhai, Vivek, Balazs, Alejandro B.

Source: In Cell 29 April 2021 184(9):2372-2383

Analytical performance of lateral flow immunoassay for SARS-CoV-2 exposure screening on venous and capillary blood samples

Authors: Black, Margaret A., Shen, Guomiao, Feng, Xiaojun, Garcia Beltran, Wilfredo F., Feng, Yang, Vasudevaraja, Varshini, Allison, Douglas, Lin, Lawrence H., Gindin, Tatyana, Astudillo, Michael, Yang, Diane, Murali, Mandakolathur, Iafrate, A. John, Jour, George, Cotzia, Paolo, Snuderl, Matija

Source: In Journal of Immunological Methods February 2021 489

COVID-19-neutralizing antibodies predict disease severity and survival

Authors: Garcia-Beltran, Wilfredo F., Lam, Evan C., Astudillo, Michael G., Yang, Diane, Miller, Tyler E., Feldman, Jared, Hauser, Blake M., Caradonna, Timothy M., Clayton, Kiera L., Nitido, Adam D., Murali, Mandakolathur R., Alter, Galit, Charles, Richelle C., Dighe, Anand, Branda, John A., Lennerz, Jochen K., Lingwood, Daniel, Schmidt, Aaron G., Iafrate, A. John, Balazs, Alejandro B.

Source: In Cell 21 January 2021 184(2):476-488

ERBB2/HOXB13 co-amplification with interstitial loss of BRCA1 defines a unique subset of breast cancers.

Authors: Mitsiades, Irene Rin, Onozato, Maristela, Iafrate, A. John, Hicks, Daniel, Gülhan, Doğa C., Sgroi, Dennis C., Rheinbay, Esther

Source: Breast Cancer Research; 12/18/2024, Vol. 26 Issue 1, p1-15, 15p

Subject Terms: HER2 positive breast cancer, FLUORESCENCE in situ hybridization, GENE amplification, MEDICAL sciences, GENE expression

Discovery of Gene Fusions in Driver-Negative Cancer Samples From the National Cancer Institute-Molecular Analysis for Therapy Choice Screening Cohort.

Authors: Kaluziak, Stefan T., Codd, Elizabeth M., Purohit, Rashi, Melli, Beatrice, Kalyan, Prinjali, Fordham, Jo Anne, Kirkpatrick, Grace, McShane, Lisa M., Chang, Ting-Chia, Yang, Guangxiao, Wang, Jinglan, Williams, P. Mickey, Karlovich, Chris, Sklar, Jeffrey, Iafrate, A. John

Source: JCO Precision Oncology; 12/5/2024, Vol. 8, p1-13, 13p

Subject Terms: GENE fusion, NUCLEOTIDE sequencing, GENETIC engineering, SOFT tissue tumors, INDIVIDUALIZED medicine, CLINICAL trials, POLYMERASE chain reaction

Company/Entity: NATIONAL Cancer Institute (U.S.)

Cytomorphologic characteristics of next-generation sequencing–positive bile duct brushing specimens

Authors: Rosenbaum, Matthew W., Arpin, Ronald, Limbocker, Jessica, Casey, Brenna, Le, Long, Dudley, Jonathan, Iafrate, A. John, Pitman, Martha B.

Source: In Journal of the American Society of Cytopathology November-December 2020 9(6):520-527

A cryptic imatinib-sensitive G3BP1-PDGFRB rearrangement in a myeloid neoplasm with eosinophilia

Authors: Jan, Max, Grinshpun, Daniel E., Villalba, Julian A., Dal Cin, Paola, Sykes, David B., Iafrate, A. John, Ebert, Benjamin L., Hobbs, Gabriela S., Nardi, Valentina ^*

Source: In Blood Advances 11 February 2020 4(3):445-448

Novel and established EWSR1 gene fusions and associations identified by next-generation sequencing and fluorescence in-situ hybridization

Authors: Krystel-Whittemore, Melissa, Taylor, Martin S., Rivera, Miguel, Lennerz, Jochen K., Le, Long P., Dias-Santagata, Dora, Iafrate, Anthony John, Deshpande, Vikram, Chebib, Ivan, Nielsen, Gunnlaugur Petur, Wu, Chin-Lee, Nardi, Valentina

Source: In Human Pathology November 2019 93:65-73

Clinical Validation of a Cell-Free DNA Gene Panel

Authors: Cheng, Ju, Cao, Yi, MacLeay, Allison, Lennerz, Jochen K., Baig, Aymen, Frazier, Ryan P., Lee, Jesse, Hu, Krista, Pacula, Maciej, Meneses, Enrique, Robinson, Hayley, Batten, Julie M., Brastianos, Priscilla K., Heist, Rebecca S., Bardia, Aditya, Le, Long P., Iafrate, A. John

Source: In The Journal of Molecular Diagnostics July 2019 21(4):632-645

Expediting Comprehensive Molecular Analysis to Optimize Initial Treatment of Lung Cancer Patients With Minimal Smoking History

Authors: Dagogo-Jack, Ibiayi, Robinson, Hayley, Mino-Kenudson, Mari, Farago, Anna F., Kamesan, Vashine, Iafrate, A. John, Shaw, Alice T., Lennerz, Jochen K.

Source: In Journal of Thoracic Oncology May 2019 14(5):835-843

Comparative Analysis of MYB Expression by Immunohistochemistry and RNA Sequencing in Clinical Gene Fusion Detection in Adenoid Cystic Carcinoma.

Authors: Fisch, Adam S., Farahani, Alexander A., Thierauf, Julia, Iafrate, A. John, Lennerz, Jochen K., Faquin, William C.

Source: Head & Neck Pathology; 10/26/2024, Vol. 18 Issue 1, p1-11, 11p