Diagnostic value of urinary and serum IgG antibodies in evaluating drug treatment response in strongyloidiasis assessed by fecal examination and digital droplet PCR.

Authors: Wongphutorn, Phattharaphon^1,2 (AUTHOR), Kopolrat, Kulthida Y.³ (AUTHOR), Worasith, Chanika⁴ (AUTHOR), Eamudomkarn, Chatanun⁵ (AUTHOR) chatea@kku.ac.th, Hongsrichan, Nuttanan⁵ (AUTHOR), Pitaksakulrat, Opal⁵ (AUTHOR), Sithithaworn, Jiraporn⁶ (AUTHOR), Tippayawat, Patcharaporn⁶ (AUTHOR), Techasen, Anchalee⁶ (AUTHOR), Noordin, Rahmah⁷ (AUTHOR), Crellen, Thomas⁸ (AUTHOR), Sithithaworn, Paiboon^2,5 (AUTHOR) paib_sit@kku.ac.th

Source: PLoS ONE. 12/3/2024, Vol. 19 Issue 12, p1-18. 18p.

Subject Terms: *IMMUNODIAGNOSIS, *ENZYME-linked immunosorbent assay, *PARASITIC diseases, *IMMUNOGLOBULIN G, *STRONGYLOIDIASIS

Phenotypic and Functional Outcomes in Macrophages Exposed to an Environmentally Relevant Mixture of Organophosphate Esters in Vitro.

Authors: Giles, Braeden H.^1,2, Kukolj, Nikola^1,2, Mann, Koren K.^1,2, Robaire, Bernard^1,3 bernard.robaire@mcgill.ca

Source: Environmental Health Perspectives. Aug2024, Vol. 132 Issue 8, p087002-1-087002-13. 13p.

Subject Terms: *Antibiotics, *Dust, *Homeostasis, *Organophosphorus compounds, *Environmental exposure, *Pollutants, *Plasticizers, *Toxicity testing, *Biomarkers, *Gram-negative bacteria, Lipid analysis, Cardiovascular disease related mortality, In vitro studies, Flow cytometry, Lysosomes, Fluorescent dyes, Macrophages, Mononuclear leukocytes, Phospholipids, Research funding, Functional assessment, Immunoglobulins, In vivo studies, Oxidative stress, Immune system, Immunodiagnosis, Cell motility, Descriptive statistics, Fireproofing agents, Cell lines, Cell culture, Reactive oxygen species, Cholesterol, Analysis of variance, Microscopy, Cytokines, Comparative studies, Phenotypes, Immunologic diseases, Gram-positive bacteria, Phagocytosis, Cell surface antigens, Disease complications

Geographic Terms: Canada

Evaluation of the Impact of BaP Exposure on the Gut Microbiota and Allergic Responses in an OVA-Sensitized Mouse Model.

Authors: Beibei Du^1,2, Xiaojun Xiao³, Huailing Wang³, Wenxi Li^2,4, Zhongkui Xia², Pingchang Yang^3,5, Shau-Ku Huang^5,6,7, Ruyi Yuan³, Jie Liu³, Mo Han^2,8,9, Yuanqiang Zou^2,8,9,10, Jiahui Zhu², Dongdong He², Jinli Lyu², Xin Jin^1,2, Xun Xu², Jian Wang², Huanming Yang^2,10, Liang Xiao^1,2,9,10 xiaoliang@genomics.cn, Xiaoyu Liu³ lxy0901@szu.edu.cn

Source: Environmental Health Perspectives. Jun2023, Vol. 131 Issue 6, p067004-1-067004-15. 15p. 1 Color Photograph, 1 Diagram, 1 Chart, 4 Graphs.

Subject Terms: *Animal experimentation, *Hydrocarbons, *Allergies, *Allergens, Inflammation prevention, Albumins, In vitro studies, Cytokines, Statistics, Kruskal-Wallis Test, Analysis of variance, Gut microbiome, Immunohistochemistry, Permeability, Quantitative research, Human microbiota, Genomes, Enzyme-linked immunosorbent assay, Descriptive statistics, Cell surface antigens, Bacterial diseases, Data analysis, Data analysis software, Immunodiagnosis, Mice

Molecular and immunological diagnosis of Monkeypox virus in the clinical laboratory.

Authors: Hao Liao¹, Jiuxin Qu¹, Hongzhou Lu¹ luhongzhou@szsy.sustech.edu.cn

Source: Drug Discoveries & Therapeutics. Dec2022, Vol. 16 Issue 6, p300-304. 5p.

Subject Terms: *MONKEYPOX, *IMMUNODIAGNOSIS, *MOLECULAR diagnosis, *PATHOLOGICAL laboratories, *VIRUS diseases, *VIRAL transmission

Geographic Terms: CHONGQING (China)

Consensus on the Key Characteristics of Immunotoxic Agents as a Basis for Hazard Identification.

Authors: Germolec, Dori R.¹, Lebrec, Herve², Anderson, Stacey E.³, Burleson, Gary R.⁴, Cardenas, Andres⁵, Corsini, Emanuela⁶, Elmore, Sarah E.⁷, Kaplan, Barbara L. F.⁸, Lawrence, B. Paige^9,10, Lehmann, Geniece M.¹¹, Maier, Curtis C.¹², McHale, Cliona M.⁵, Myers, L. Peyton¹³, Pallardy, Marc¹⁴, Rooney, Andrew A.¹, Zeise, Lauren⁷, Luoping Zhang⁵, Smith, Martyn T.⁵ martynts@berkeley.edu

Source: Environmental Health Perspectives. Oct2022, Vol. 130 Issue 10, p105001-1-105001-16. 16p. 4 Diagrams.

Subject Terms: *Carcinogens, *Hazardous substances, *Apoptosis, *Immunity, Consensus (Social sciences), Cell differentiation, Committees, Medical personnel, Immune system, Immunosuppression, Risk assessment, Cellular signal transduction, Cell communication, Expertise, Cell proliferation, Cell surface antigens, Biological assay, Immunodiagnosis, Antigens

A first attempt at determining the antibody-specific pattern of Platynosomum fastosum crude antigen and identification of immunoreactive proteins for immunodiagnosis of feline platynosomiasis.

Authors: Kyi Soe, Babi¹ babikyisoe.vet@gmail.com, Adisakwattana, Poom² poom.adi@mahidol.edu, Reamtong, Onrapak³ onrapak.rea@mahidol.edu, Anuracpreeda, Panat⁴ panat.anu@mahidol.edu, Sukhumavasi, Woraporn⁵ vetkwan@hotmail.com

Source: Veterinary World. Aug2022, Vol. 15 Issue 8, p2029-2038. 10p.

Subject Terms: *PROTEOMICS, *IMMUNODIAGNOSIS, *BILE ducts, *LIQUID chromatography-mass spectrometry, *ADENOSINE triphosphate, *CALPROTECTIN, *IMMUNOGLOBULINS

Immunological Evolution of a Cohort of HIV-2 Infected Patients: Peculiarities of an Underestimated Infection.

Authors: Fumarola, Benedetta^1,2 benni.fumarola@gmail.com, Calza, Stefano³, Renzetti, Stefano³, El Hamad, Issa¹, Pezzoli, Maria C.¹, Izzo, Ilaria¹, Antoni, Melania Degli^1,2, Chiesa, Annacarla^1,2, De Francesco, Maria⁴, Quiros-Roldan, Eugenia^1,2, Caruso, Arnaldo⁴, Castelli, Francesco^1,2, Focà, Emanuele^1,2

Source: Mediterranean Journal of Hematology & Infectious Diseases. 2022, Vol. 14 Issue 1, p1-7. 7p.

Subject Terms: *HIV, *IMMUNODIAGNOSIS, *CD4 antigen, *AIDS

Geographic Terms: ITALY

Flavonoids of Andrographis paniculata regulate hepatitis B virus replication and hepatocellular carcinoma progression: evidence from computational and experimental studies.

Authors: Patil, Vishal S., Harish, Darasaguppe R., Charla, Rajitha, Bhandare, Vishwambhar Vishnu, Gujarathi, Swarup S., Beerwala, Faizan A., Patil, Priyanka P., Jalalpure, Sunil S., Hegde, Harsha V., Roy, Subarna

Source: BMC Complementary Medicine & Therapies; 3/8/2025, Vol. 25 Issue 1, p1-15, 15p

Subject Terms: PHYTOTHERAPY, COMPUTER simulation, IN vitro studies, COMPUTER-assisted molecular modeling, RESEARCH funding, FLAVONOIDS, IMMUNODIAGNOSIS, DNA, REVERSE transcriptase polymerase chain reaction, TIME series analysis, PLANT extracts, GENE expression, RNA, HEPATITIS B, MOLECULAR structure, REVERSE transcriptase inhibitors, HEPATOCELLULAR carcinoma, CELL surface antigens

Enhanced antibiotic release and biocompatibility with simultaneous addition of N-acetylcysteine and vancomycin to bone cement: a potential replacement for high-dose antibiotic-loaded bone cement.

Authors: Tseng, Tzu-Hao, Chang, Chih-Hao, Chen, Chien-Lin, Chiang, Hongsen, Wang, Jyh-Horng, Young, Tai-Horng

Source: Journal of Orthopaedic Surgery & Research; 3/6/2025, Vol. 20 Issue 1, p1-9, 9p

Subject Terms: MATERIALS testing, DRUG toxicity, ANTIBIOTICS, PROSTHESIS-related infections, T-test (Statistics), IMMUNODIAGNOSIS, DESCRIPTIVE statistics, BIOMEDICAL materials, ACETYLCYSTEINE, VANCOMYCIN, BONE cements, POLYMETHYLMETHACRYLATE, BIOLOGICAL assay, CELL survival, DATA analysis software, CELL surface antigens, PHARMACODYNAMICS

Study on the anti-HBV activity of matrine alkaloids from Oxytropis ochrocephala by MTT, 3d-QSAR, molecular docking and molecular dynamics simulation.

Authors: Zhang, Ya-Kun^1,2, Tong, Jian-Bo², jianbotong@aliyun.com, Tan, Jing¹, Yang, Min¹, Xing, Xiao-Yu², Zeng, Yan-Rong¹, Xue, Zhan^1,3, 2544173350@qq.com, Tan, Cheng-Jian¹, tcj1229@163.com

Source: Journal of Asian Natural Products Research; Mar2025, Vol. 27 Issue 3, p442-459, 18p

A novel mechanism in regulating drug sensitivity, growth, and apoptosis of bortezomib-resistant multiple myeloma cells: the USP4/KLF2/HMGA2 cascade.

Authors: Liu, Ziyi, Li, Xiaoliang, He, Yin, Xie, Fengqun, Zhang, Yanrong, Huang, Mufang, Wang, Yinjingwen, Zhu, Weijian

Source: Journal of Orthopaedic Surgery & Research; 3/1/2025, Vol. 20 Issue 1, p1-13, 13p

Subject Terms: MULTIPLE myeloma, PROTEINS, FLOW cytometry, DRUG resistance in cancer cells, APOPTOSIS, CELL proliferation, PROBABILITY theory, REVERSE transcriptase polymerase chain reaction, IMMUNODIAGNOSIS, BORTEZOMIB, CELL lines, MESSENGER RNA, GENE expression, ONE-way analysis of variance, ANALYSIS of variance, IMMUNOBLOTTING, CELL surface antigens

Antioxidant and cytotoxic properties of protocorm-derived phenol-rich fractions of Dendrobium amoenum.

Authors: Paudel, Mukti Ram, Sharma, Sujata, Joshi, Pusp Raj, Pant, Basant, Wagner, Sven H., Gurung, Pritam, Pant, Krishna Kumar, Pant, Bijaya

Source: BMC Complementary Medicine & Therapies; 2/18/2025, Vol. 25 Issue 1, p1-11, 11p

Subject Terms: SEED physiology, IN vitro studies, RESEARCH funding, FLAVONOIDS, IMMUNODIAGNOSIS, DESCRIPTIVE statistics, PLANT extracts, ANTIOXIDANTS, PHENOLS, ORGANIC compounds, CELL surface antigens, PLANT physiology, CULTURES (Biology)

Cytotoxic and immunomodulatory properties of Tinospora cordifolia, Boerhaavia diffusa, Berberis aristata, and Ocimum basilicum extracts against HPV-positive cervical cancer cell line.

Authors: Vaghasia, Harsha, Patel, Rahul, Prajapati, Jignesh, Shah, Krupa, Saraf, Meenu, Rawal, Rakesh M

Source: BMC Complementary Medicine & Therapies; 2/17/2025, Vol. 25 Issue 1, p1-18, 18p

Subject Terms: THERAPEUTIC use of antineoplastic agents, DNA analysis, PAPILLOMAVIRUS diseases, IN vitro studies, FLOW cytometry, WOUND healing, CERVIX uteri tumors, T-test (Statistics), QUALITATIVE research, CISPLATIN, PHENOMENOLOGICAL biology, T cells, ANTINEOPLASTIC agents, HERBAL medicine, CELL proliferation, ENZYME-linked immunosorbent assay, POLYMERASE chain reaction, PROGRAMMED death-ligand 1, IMMUNE system, CELL motility, IMMUNODIAGNOSIS, CELL cycle, PAPILLOMAVIRUSES, DESCRIPTIVE statistics, PHYTOCHEMICALS, BIOCHEMISTRY, PLANT extracts, CANCER chemotherapy, CELL lines, MUTAGENICITY testing, ONE-way analysis of variance, CELL survival, DATA analysis software, CD4 antigen, IMMUNOMODULATORS, IMMUNITY, CELL surface antigens, PHARMACODYNAMICS

Exploring the anticancer potential of extracts and compounds from the heartwood of Cotinus coggygria Scop. wild growing in Serbia.

Authors: Pašić, Ivana, Novaković, Miroslav, Tešević, Vele, Milosavljević, Slobodan, Petrović, Nina, Stanojković, Tatjana, Matić, Ivana Z.

Source: BMC Complementary Medicine & Therapies; 2/4/2025, Vol. 25 Issue 1, p1-18, 18p

Subject Terms: PHYTOTHERAPY, FLOW cytometry, RESEARCH funding, NUCLEAR magnetic resonance spectroscopy, HERBAL medicine, ANTINEOPLASTIC agents, FLAVONOIDS, ETHANOL, HYDROCARBONS, POLYMERASE chain reaction, IMMUNODIAGNOSIS, DESCRIPTIVE statistics, PLANT extracts, CELL lines, MOLECULAR structure, METHANOL, WATER, TUMORS, COMPARATIVE studies, CELL surface antigens, PHARMACODYNAMICS

Geographic Terms: SERBIA

Tissue-friendly dentin treatments as a potential element in revascularization protocol (ex-vivo study).

Authors: Khalil, Hala Fayek, Metwalli, Nadia Ezz El Din, Magdy, Sara, Shamel, Mohamed

Source: BMC Oral Health; 2/3/2025, Vol. 25 Issue 1, p1-13, 13p

Subject Terms: ENDODONTICS, VASCULAR endothelial growth factors, DENTIN, CELL proliferation, TISSUE adhesions, CHELATING agents, CELL physiology, POLYMERASE chain reaction, REVASCULARIZATION (Surgery), SODIUM hypochlorite, IMMUNODIAGNOSIS, DESCRIPTIVE statistics, REGENERATION (Biology), GENE expression, CALCIUM, CURCUMIN, SCANNING electron microscopy, CELL differentiation, CELL survival, STEM cells, CELL surface antigens, TRANSFORMING growth factors-beta, PHARMACODYNAMICS

Four new homoisoflavonoids from Caesalpinia pulcherrima.

Authors: Zheng, Yu-Cheng¹, Gu, Wen-Jian², Shu, Ren-Geng³, Zhang, Pu-Zhao¹, zhpuzh@163.com

Source: Journal of Asian Natural Products Research; Feb2025, Vol. 27 Issue 2, p126-135, 10p

Distinct NF-kB Regulation Favors a Synergic Action of Pevonedistat and Laduviglusib in B-Chronic Lymphocytic Leukemia Cells Ex Vivo.

Authors: Arenas, Víctor, Castaño, Jose Luis, Domínguez, Juan José, Yáñez, Lucrecia, Pipaón, Carlos

Source: Cancers; Feb2025, Vol. 17 Issue 3, p533, 18p

Subject Terms: THERAPEUTIC use of proteins, CHRONIC lymphocytic leukemia, NF-kappa B, PROTEIN kinase inhibitors, PROTEINS, RESEARCH funding, APOPTOSIS, CELLULAR signal transduction, IMMUNODIAGNOSIS, MESSENGER RNA, GENE expression profiling, DRUG synergism, CELL surface antigens

Polo-like Kinase 1 Inhibitors Demonstrate In Vitro and In Vivo Efficacy in Preclinical Models of Small Cell Lung Cancer.

Authors: Zhang, Guojing, Pannucci, Abbe, Ivanov, Andrey A., Switchenko, Jeffrey, Sun, Shi-Yong, Sica, Gabriel L., Liu, Zhentao, Huang, Yufei, Schmitz, John C., Owonikoko, Taofeek K.

Source: Cancers; Feb2025, Vol. 17 Issue 3, p446, 16p

Subject Terms: PROTEIN kinase inhibitors, BIOLOGICAL models, IN vitro studies, RESEARCH funding, ADENOSINE triphosphate, TUMOR markers, IN vivo studies, IMMUNODIAGNOSIS, XENOGRAFTS, MICE, CELL lines, DRUG efficacy, ANIMAL experimentation, SMALL cell carcinoma, CELL surface antigens, CHEMICAL inhibitors

Targeting Ataxia Telangiectasia-Mutated and Rad3-Related for Anaplastic Thyroid Cancer.

Authors: Lin, Shu-Fu, Hsueh, Chuen, Chen, Wei-Yi, Chou, Ting-Chao, Wong, Richard J.

Source: Cancers; Feb2025, Vol. 17 Issue 3, p359, 17p

Subject Terms: THERAPEUTIC use of antineoplastic agents, ANAPLASTIC thyroid cancer, PROTEIN kinase inhibitors, IN vitro studies, RESEARCH funding, ENZYME inhibitors, APOPTOSIS, ANTINEOPLASTIC agents, ATAXIA telangiectasia, TUMOR markers, IMMUNODIAGNOSIS, XENOGRAFTS, CELL lines, DOSE-effect relationship in pharmacology, DNA damage, ANIMAL experimentation, GENETIC mutation, MEMBRANE proteins, CELL surface antigens, CASPASES, PHARMACODYNAMICS

Pharmacological Management of IgG4-Related Disease: From Traditional to Mechanism-Based Targeted Therapies: Advances in IgG4-Related Disease Management: M. Akiyama et al.

Authors: Akiyama, Mitsuhiro, Alshehri, Waleed, Saito, Koichi, Takeuchi, Tsutomu, Kaneko, Yuko

Source: Drugs & Aging; Feb2025, Vol. 42 Issue 2, p111-126, 16p

Subject Terms: AUTOIMMUNE disease prevention, AUTOIMMUNE disease diagnosis, HEALTH literacy, MEDICAL technology, IMMUNOGLOBULIN G, PROTEIN-tyrosine kinase inhibitors, IMMUNODIAGNOSIS, CELLULAR signal transduction, AUTOIMMUNE diseases, CYTOKINES, GLUCOCORTICOIDS, INTERLEUKINS, CELL surface antigens

Geographic Terms: UNITED States