Transcranial Magnetic Stimulation Enhances the Therapeutic Effect of IGF-Trap in Intracerebral Glioma Models

Authors: Stephanie Perrino, Udi Vazana, Ofer Prager, Lior Schori, Gal Ben-Arie, Anna Minarik, Yinhsuan Michely Chen, Orçun Haçariz, Masakazu Hashimoto, Yiftach Roth, Gabriel S. Pell, Alon Friedman, Pnina Brodt

Source: Pharmaceuticals, Vol 17, Iss 12, p 1607 (2024)

Subject Terms: glioma, animal models, rTMS, IGF, IGF-Trap, therapy, Medicine, Pharmacy and materia medica, RS1-441

File Description: electronic resource

Relation: https://www.mdpi.com/1424-8247/17/12/1607; https://doaj.org/toc/1424-8247

Access URL: https://doaj.org/article/14610c330b7a46aa9029b89570631274

Insulin-Like Growth Factors in Development, Cancers and Aging

Contributors: Werner, Haim

Subject Terms: IGF-I, IGF-II, insulin, IGF-IR, IRs, tyrosine kinase receptor, GPCRs, hybrids, phosphorylation, G-proteins, β-arrestins, functional RTK/GPCR hybrid, nuclear translocation, IGF-I receptor, signaling, targeted therapeutics, IGF-Trap, IGF system, IGFBP-3, IGFBP-3R, TMEM219, anti-tumor, anti-metastatic, agonists, mAb therapy, IGF-1, IGFBP-1, older adults, longevity, health-span, age-related disease, cognitive impairment, diabetes, mitochondria, growth hormone, insulin-like growth factor-1, aging, oxidative stress, senescence, longitudinal study, IGFBP, mouse models, skeletal muscle, MSCs, myogenesis, glucose regulated protein (GRP) 94, insulin-like growth factor, obligate chaperone, hypertrophy, atrophy, cachexia, muscle regeneration, autophagy, IGF-1R, insulin receptor, IR-A, structural studies, receptor activation, Research and information: general, Biology, life sciences

File Description: image/jpeg

Access URL: https://directory.doabooks.org/handle/20.500.12854/76486
https://mdpi.com/books/pdfview/book/3932

Targeting the IGF-Axis in Cultured Pediatric High-Grade Glioma Cells Inhibits Cell Cycle Progression and Survival

Authors: Yinhsuan Michely Chen, Matthew Leibovitch, Michele Zeinieh, Nada Jabado, Pnina Brodt

Source: Pharmaceuticals, Vol 16, Iss 2, p 297 (2023)

Subject Terms: pediatric glioma, IGF signaling, the IGF-Trap, nuclear translocation, Medicine, Pharmacy and materia medica, RS1-441

File Description: electronic resource

Relation: https://www.mdpi.com/1424-8247/16/2/297; https://doaj.org/toc/1424-8247

Access URL: https://doaj.org/article/f99b3ce56232472e89038a97b3d7ec18

Identification of a Resistance Mechanism to IGF-IR Targeting in Human Triple Negative MDA-MB-231 Breast Cancer Cells

Authors: Jennifer Tsui, Shu Qi, Stephanie Perrino, Matthew Leibovitch, Pnina Brodt

Source: Biomolecules, Vol 11, Iss 4, p 527 (2021)

Subject Terms: triple negative breast cancer, IGF signaling, the IGF-Trap, drug resistance, FGFR1, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.mdpi.com/2218-273X/11/4/527; https://doaj.org/toc/2218-273X

Access URL: https://doaj.org/article/b5b05eddb9a14f1c91dc07b23bd76255

TMS-Induced Controlled BBB Opening: Preclinical Characterization and Implications for Treatment of Brain Cancer

Authors: Udi Vazana, Lior Schori, Uri Monsonego, Evyatar Swissa, Gabriel S. Pell, Yiftach Roth, Pnina Brodt, Alon Friedman, Ofer Prager

Source: Pharmaceutics, Vol 12, Iss 10, p 946 (2020)

Subject Terms: blood–brain barrier, brain drug delivery, repetitive transcranial magnetic stimulation, safety, time dependency, IGF-Trap, Pharmacy and materia medica, RS1-441

File Description: electronic resource

Relation: https://www.mdpi.com/1999-4923/12/10/946; https://doaj.org/toc/1999-4923

Access URL: https://doaj.org/article/e2aa00c3a0ac490ca9fa3e38cfa952de

Targeting the IGF-Axis for Cancer Therapy: Development and Validation of an IGF-Trap as a Potential Drug

Authors: Yinhsuan Michely Chen, Shu Qi, Stephanie Perrino, Masakazu Hashimoto, Pnina Brodt

Source: Cells, Vol 9, Iss 5, p 1098 (2020)

Subject Terms: IGF-I receptor, signaling, targeted therapeutics, IGF-Trap, Cytology, QH573-671

File Description: electronic resource

Relation: https://www.mdpi.com/2073-4409/9/5/1098; https://doaj.org/toc/2073-4409

Access URL: https://doaj.org/article/4b4690c9c9b94c0d8017cd8ccb9e1854