Revealing potential Rab proteins participate in regulation of secretory autophagy machinery

Authors: Pei‐Wen Lin, Man‐Ling Chu, Yu‐Wen Liu, Yu‐Cing Chen, Yao‐Hsiang Shih, Sheng‐Hui Lan, Shang‐Ying Wu, I‐Ying Kuo, Hong‐Yi Chang, Hsiao‐Sheng Liu, Ying‐Ray Lee

Source: Kaohsiung Journal of Medical Sciences, Vol 40, Iss 7, Pp 642-649 (2024)

Subject Terms: Rab protein, secretory autophagy, unconventional protein secretion, Medicine (General), R5-920

File Description: electronic resource

Relation: https://doaj.org/toc/1607-551X; https://doaj.org/toc/2410-8650

Access URL: https://doaj.org/article/e258c7ae7ddd4ed3a3137a5a976dbe9c

Deubiquitinating enzymes: potential regulators of the tumor microenvironment and implications for immune evasion

Authors: Sheng-Kai Hsu, Chon-Kit Chou, I-Ling Lin, Wen-Tsan Chang, I-Ying Kuo, Chien-Chih Chiu

Source: Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-16 (2024)

Subject Terms: Deubiquitinating enzymes (DUBs), Tumor microenvironment (TME), Immune evasion, Posttranslational modification (PTM), Tumor-associated macrophage (TAM), Regulatory T cell (Treg), Medicine, Cytology, QH573-671

File Description: electronic resource

Relation: https://doaj.org/toc/1478-811X

Access URL: https://doaj.org/article/be832de6c2344d1585efd96155d54739

Rab37 mediates trafficking and membrane presentation of PD-1 to sustain T cell exhaustion in lung cancer

Authors: Wan-Ting Kuo, I-Ying Kuo, Hung-Chia Hsieh, Ssu-Ting Wu, Wu-Chou Su, Yi-Ching Wang

Source: Journal of Biomedical Science, Vol 31, Iss 1, Pp 1-20 (2024)

Subject Terms: PD-1, Rab37, Membrane trafficking, T cell, Lung cancer, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/1423-0127

Access URL: https://doaj.org/article/f40fd3e99c6c4fc29da14694cc63407c

Impact of Oseltamivir and Diabetes Development

Authors: Bor-Show Tzang, Chih-Chen Tzang, Pei-Hua Chuang, I-Ying Kuo, Yu-Chun Pan, Pei-Hsun Wu, Tsai-Ching Hsu

Source: Pharmaceuticals, Vol 18, Iss 1, p 128 (2025)

Subject Terms: antiviral therapy, neuraminidase inhibitors, retrospective cohort study, Taiwan National Health Insurance Research Database, Medicine, Pharmacy and materia medica, RS1-441

File Description: electronic resource

Relation: https://www.mdpi.com/1424-8247/18/1/128; https://doaj.org/toc/1424-8247

Access URL: https://doaj.org/article/c9c2400b1d504c749d28e80d0f2d2bd6

PTPN23 ubiquitination by WDR4 suppresses EGFR and c-MET degradation to define a lung cancer therapeutic target

Authors: Shaifali Singh, Nai Yang Yeat, Ya-Ting Wang, Shu-Yu Lin, I-Ying Kuo, Kuen-Phon Wu, Won-Jing Wang, Wen-Ching Wang, Wu-Chou Su, Yi-Ching Wang, Ruey-Hwa Chen

Source: Cell Death and Disease, Vol 14, Iss 10, Pp 1-17 (2023)

Subject Terms: Cytology, QH573-671

File Description: electronic resource

Relation: https://doaj.org/toc/2041-4889

Access URL: https://doaj.org/article/aaf04d699c2f45f6a88e5341ad07b036

Correction: PTPN23 ubiquitination by WDR4 suppresses EGFR and c-MET degradation to define a lung cancer therapeutic target

Authors: Shaifali Singh, Nai Yang Yeat, Ya-Ting Wang, Shu-Yu Lin, I-Ying Kuo, Kuen-Phon Wu, Won-Jing Wang, Wen-Ching Wang, Wu-Chou Su, Yi-Ching Wang, Ruey-Hwa Chen

Source: Cell Death and Disease, Vol 15, Iss 7, Pp 1-1 (2024)

Subject Terms: Cytology, QH573-671

File Description: electronic resource

Relation: https://doaj.org/toc/2041-4889

Access URL: https://doaj.org/article/9922c5b5578240c4ba3a59bfacda25c3

Dysregulation of SOX17/NRF2 axis confers chemoradiotherapy resistance and emerges as a novel therapeutic target in esophageal squamous cell carcinoma

Authors: Chih-Hsiung Hsieh, Wen-Hui Kuan, Wei-Lun Chang, I-Ying Kuo, Hsun Liu, Dar-Bin Shieh, Hsuan Liu, Bertrand Tan, Yi-Ching Wang

Source: Journal of Biomedical Science, Vol 29, Iss 1, Pp 1-20 (2022)

Subject Terms: Chemoradiotherapy resistance, NRF2, SOX17, DNA methyltransferases, And esophageal squamous cell carcinoma, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/1423-0127

Access URL: https://doaj.org/article/30217219feb34a9f871a60222942de23

SOX17 overexpression sensitizes chemoradiation response in esophageal cancer by transcriptional down-regulation of DNA repair and damage response genes

Authors: I-Ying Kuo, Yu-Lin Huang, Chien-Yu Lin, Chien-Hsun Lin, Wei-Lun Chang, Wu-Wei Lai, Yi-Ching Wang

Source: Journal of Biomedical Science, Vol 26, Iss 1, Pp 1-14 (2019)

Subject Terms: SOX17, Transcription regulation, Resistance, DNA repair, Concurrent chemoradiation therapy, Esophageal cancer, Medicine

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s12929-019-0510-4; https://doaj.org/toc/1423-0127

Access URL: https://doaj.org/article/b8627b0348134ae5a2634eff53ad8a20

Factor VII-Induced MicroRNA-135a Inhibits Autophagy and Is Associated with Poor Prognosis in Hepatocellular Carcinoma

Authors: Kuang-Tzu Huang, I-Ying Kuo, Ming-Chao Tsai, Chun-Hsien Wu, Li-Wen Hsu, Li-Yu Chen, Chao-Pin Kung, Yu-Fan Cheng, Shigeru Goto, Yu-Wei Chou, Chao-Long Chen, Chih-Che Lin, Kuang-Den Chen

Source: Molecular Therapy: Nucleic Acids, Vol 9, Iss C, Pp 274-283 (2017)

Subject Terms: hepatocellular carcinoma, FVII, miR-135a, autophagy, Atg14, recurrence, microvascular invasion, survival, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2162253117302639; https://doaj.org/toc/2162-2531

Access URL: https://doaj.org/article/48e5dc56d831470086092efeab740567

A prognostic predictor panel with DNA methylation biomarkers for early-stage lung adenocarcinoma in Asian and Caucasian populations.

Authors: I-Ying Kuo^1,2, Jayu Jen^1,2, Lien-Huei Hsu^3,4, Han-Shui Hsu⁵, Wu-Wei Lai⁶ wwlai@mail.ncku.edu.tw, Yi-Ching Wang^1,2 ycw5798@mail.ncku.edu.tw

Source: Journal of Biomedical Science. 8/2/2016, Vol. 23, p1-10. 10p. 1 Diagram, 3 Charts, 3 Graphs.

Subject Terms: *DNA methylation, *BIOMARKERS, *ADENOCARCINOMA, *LUNG cancer diagnosis, *METHYLATION, *DIAGNOSIS

Targeting protumor factor chitinase-3-like-1 secreted by Rab37 vesicles for cancer immunotherapy.

Authors: Pei-Shan Yang, Min-Hua Yu, Ya-Chin Hou, Chih-Peng Chang, Shao-Chieh Lin, I-Ying Kuo, Pei-Chia Su, Hung-Chi Cheng, Wu-Chou Su, Yan-Shen Shan, Yi-Ching Wang

Source: Theranostics; 2022, Vol. 12 Issue 1, p340-361, 22p

Converged Rab37/IL-6 trafficking and STAT3/PD-1 transcription axes elicit an immunosuppressive lung tumor microenvironment.

Authors: I.-Ying Kuo, You-En Yang, Pei-Shan Yang, Yu-Jou Tsai, Hong-Tai Tzeng, Hung-Chi Cheng, Wan-Ting Kuo, Wu-Chou Su, Chih-Peng Chang, Yi-Ching Wang

Source: Theranostics; 2021, Vol. 11 Issue 14, p7029-7044, 16p

Deregulation of SLIT2-Mediated Cdc42 Activity Is Associated with Esophageal Cancer Metastasis and Poor Prognosis.

Authors: Ruo-Chia Tseng, Jia-Ming Chang, Jeng-Hung Chen, Way-Ren Huang, Yen-An Tang, I-Ying Kuo, Jing-Jou Yan, Wu-Wei Lai, Yi-Ching Wang

Source: Journal of Thoracic Oncology; Jan2015, Vol. 10 Issue 1, p189-198, 10p

Recent advances in conventional and unconventional vesicular secretion pathways in the tumor microenvironment

Authors: I.-Ying Kuo, Chih-Hsiung Hsieh, Wan-Ting Kuo, Chih-Peng Chang, Yi-Ching Wang

Source: Journal of Biomedical Science, Vol 29, Iss 1, Pp 1-26 (2022)

Subject Terms: Rab GTPase, Exocytosis, Extracellular vesicle, Secretory autophagy, Vesicle trafficking, Tumor microenvironment, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/1423-0127

Access URL: https://doaj.org/article/f3303bda222b456e8173532701dfca56