A Smart CA IX-Targeting and pH-Responsive Nano-Mixed Micelles for Delivery of FB15 with Superior Anti-Breast Cancer Efficacy

Authors: Liu X, Zhao J, Liu F, Xie Z, Lei X, Wang Z, Yang Z, Zhou Y, Tang G

Source: International Journal of Nanomedicine, Vol Volume 19, Pp 10247-10262 (2024)

Subject Terms: carbonic anhydrase ix-targeting, fb15, hypoxia inducible factor-1, nano-mixed micelles, ph-responsive, Medicine (General), R5-920

File Description: electronic resource

Relation: https://www.dovepress.com/a-smart-ca-ix-targeting-and-ph-responsive-nano-mixed-micelles-for-deli-peer-reviewed-fulltext-article-IJN; https://doaj.org/toc/1178-2013

Access URL: https://doaj.org/article/0af1b03e93bd48f384cd645cf565607e

Regulation of Hypoxia Inducible Factor via Histone Deacetylase 3 Inhibitor Valproic Acid: A computational Study between HIF-1a, Histone Deacetylase, and Valproic Acid

Authors: Garg, Yami, Kumar, Pravir

Source: 2021 5th International Conference on Information Systems and Computer Networks (ISCON) Information Systems and Computer Networks (ISCON), 2021 5th International Conference on. :1-4 Oct, 2021

Relation: 2021 5th International Conference on Information Systems and Computer Networks (ISCON)

Cannabidiol effectively prevents oxidative stress and stabilizes hypoxia-inducible factor-1 alpha (HIF-1α) in an animal model of global hypoxia

Authors: Hanna Kletkiewicz, Michał S. Wojciechowski, Justyna Rogalska

Source: Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)

Subject Terms: Perinatal hypoxia, Cannabidiol, Oxidative stress, Lipid peroxidation, Antioxidants, Hypoxia-inducible factor-1 alpha, Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/5ff0d1c4f6c84debb3fde1fae2afed69

Targeting hypoxia inducible factor-1 alpha in rheumatoid arthritis: Rationale, opportunities and challenges

Authors: George D. Kalliolias, Athanasios G. Papavassiliou

Source: Pharmacological Research, Vol 210, Iss , Pp 107537- (2024)

Subject Terms: Hypoxia inducible factor-1 alpha, Rheumatoid arthritis, Epigenetics, Metabolic reprograming, Citrullination, Therapeutics. Pharmacology, RM1-950

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Relation: http://www.sciencedirect.com/science/article/pii/S1043661824004821; https://doaj.org/toc/1096-1186

Access URL: https://doaj.org/article/70cd9ac076e64113852e003d6a37dc78

Dynamics simulations of hypoxia inducible factor-1 regulatory network in cancer using formal verification techniques

Authors: Hafiz Muhammad Faraz Azhar, Muhammad Tariq Saeed, Ishrat Jabeen

Source: Frontiers in Molecular Biosciences, Vol 11 (2024)

Subject Terms: hypoxia-inducible factor-1 (HIF-1), vascular endothelial growth factor (VEGF), oglycosylation transferase (OGT), glucose transporter-1 (GLUT-1), extracellular single regulated kinase (ERK), cellular myelocytomatosis oncogene (C-MYC), Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fmolb.2024.1386930/full; https://doaj.org/toc/2296-889X

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The role of hypoxic microenvironment in autoimmune diseases

Authors: Xun Gong, Su-Yin Yang, Zhen-Yu Wang, Min Tang

Source: Frontiers in Immunology, Vol 15 (2024)

Subject Terms: hypoxic microenvironment, autoimmune diseases, rheumatoid arthritis, hypoxia-inducible factor-1, immune cells, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2024.1435306/full; https://doaj.org/toc/1664-3224

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Hypoxia inducible factor-1alpha expression correlates with inflammatory injury of blood-brain barrier which influences perihaematomal edema after intracerebral hemorrhage

Authors: Wu, Jian ^a, Yan, Fuli ^a, Li, Yiming ^a, Liang, Mingang ^a, Guo, Yu ^{b, ⁎⁎}, Yang, Mingfei ^{c, ⁎}

Source: In Journal of Stroke and Cerebrovascular Diseases May 2025 34(5)

Effect of vitamin B12 on methotrexate-induced cardiotoxicity in rats

Authors: Nurhan Kuloğlu, Derya Karabulut, Emin Kaymak, Ali Tuğrul Akin, Tayfun Ceylan, Ayşegül Yıldırım, Birkan Yakan

Source: Iranian Journal of Basic Medical Sciences, Vol 27, Iss 6, Pp 733-739 (2024)

Subject Terms: erythropoietin, hypoxia-inducible factor-1, methotrexate, vascular endothelial growth factor, vitamin b12, Medicine

File Description: electronic resource

Relation: https://ijbms.mums.ac.ir/article_23944_077af541916d0820267451b0bfa4082c.pdf; https://doaj.org/toc/2008-3866; https://doaj.org/toc/2008-3874

Access URL: https://doaj.org/article/0367578f2ce14bd59de0462056a7d76d

Thymic gene expression analysis reveals a potential link between HIF-1A and Th17/Treg imbalance in thymoma associated myasthenia gravis

Authors: İlayda Altınönder, Mustafa Kaya, Sibel P. Yentür, Arman Çakar, Hacer Durmuş, Gülçin Yegen, Berker Özkan, Yeşim Parman, Amr H. Sawalha, Guher Saruhan-Direskeneli

Source: Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-10 (2024)

Subject Terms: Thymoma, Thymus, Myasthenia gravis, Hypoxia-inducible factor-1, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: https://doaj.org/toc/1742-2094

Access URL: https://doaj.org/article/22e3a343211b4a35a2bed8399f28723e

Hypoxia Inducible Factor-1 in Diabetes and Its Complications:a Comprehensive Reviewof Recent Research Advances

Authors: Jing Cai, Leiying Qiao, Lin Hu, Songbo Fu, Chengdong Qiao

Source: Guoji laonian yixue zazhi, Vol 45, Iss 02, Pp 229-233 (2024)

Subject Terms: hypoxia inducible factor-1, diabetes, diabetes complications, Geriatrics, RC952-954.6

File Description: electronic resource

Relation: http://gwll.publish.founderss.cn/thesisDetails#10.3969/j.issn.1674-7593.2024.02.020&lang=en; https://doaj.org/toc/1674-7593

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HIF-1α signaling: Essential roles in tumorigenesis and implications in targeted therapies

Authors: Yan Zhao, Cheng Xing, Yating Deng, Can Ye, Hongling Peng

Source: Genes and Diseases, Vol 11, Iss 1, Pp 234-251 (2024)

Subject Terms: Angiogenesis, Hematological malignancies, Hypoxia-inducible factor-1 alpha (HIF-1α), Immune escape, Targeted therapy, Medicine (General), R5-920, Genetics, QH426-470

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2352304223001058; https://doaj.org/toc/2352-3042

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Therapeutic potential of roxadustat in immune thrombocytopenia: a Mendelian randomization analysis

Authors: Ma, Jingyao ¹, Hu, Yu ¹, Dong, Shuyue ¹, Meng, Jinxi ¹, Wang, Zhifa ¹, Ouyang, Juntao ¹, Lin, Zheyan ¹, Cheng, Xiaoling ², Chen, Zhenping ³, Wu, Runhui ^{1, ∗}

Source: In Journal of Thrombosis and Haemostasis December 2024

LuQi Formula relieves ventricular remodeling through improvement of HIF-1α-mediated intestinal barrier integrity

Authors: Jirong Yan, Zhichao Xi, Jiaying Guo, Lin Xu, Xueyang Sun, Wanjing Sha, Milin Liu, Shenyu Zhao, Enrui Dai, Yu Xu, Hongxi Xu, Huiyan Qu

Source: Chinese Medicine, Vol 18, Iss 1, Pp 1-14 (2023)

Subject Terms: Ventricular remodeling, Intestinal barrier integrity, LuQi Formula, Tight junction proteins, Hypoxia inducible factor-1 alpha, Other systems of medicine, RZ201-999

File Description: electronic resource

Relation: https://doaj.org/toc/1749-8546

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Effects of Bosentan on Hypoxia, Inflammation and Oxidative Stress in Experimental Blunt Thoracic Trauma Model

Authors: Nedim Uzun, Sinem Durmus, Gonca Gercel, Burhan Aksu, Naile Fevziye Misirlioglu, Hafize Uzun

Source: Medicina, Vol 60, Iss 7, p 1148 (2024)

Subject Terms: pulmonary contusion, endothelin-1, ET-1, hypoxia-inducible factor-1 HIF-1, nuclear factor-kappa B, tumor necrosis factor-α pro-oxidant antioxidant balance, Medicine (General), R5-920

File Description: electronic resource

Relation: https://www.mdpi.com/1648-9144/60/7/1148; https://doaj.org/toc/1010-660X; https://doaj.org/toc/1648-9144

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Effect of hypoxia-inducible factor-1 alpha expression on survival in patients with metastatic cervical squamous cell carcinoma treated with first-line chemotherapy and bevacizumab

Authors: Hasan Cagri Yildirim, Hicran Anik, Deniz Ates Ozdemir, Rashad Ismayilov, Arif Akyildiz, Kerim Cayiroz, Fahri Ceyhan, Oguzalp Kavruk, Deniz Can Guven, Ozturk Ates, Alp Usubutun, Zafer Arik

Source: Biomolecules & Biomedicine (2024)

Subject Terms: Metastatic cervical cancer, squamous cell carcinoma (SCC), vascular endothelial growth factor (VEGF), hypoxia-inducible factor-1 alpha (HIF-1 alpha), bevacizumab, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.bjbms.org/ojs/index.php/bjbms/article/view/10255; https://doaj.org/toc/2831-0896; https://doaj.org/toc/2831-090X

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Regulating anaerobic metabolism and promoting myocardial ischemia-hypoxia injury by diesel particulate matter and its key component benzo[a]pyrene via targeting oxygen sensors

Authors: Hao YIN, Ze ZHANG, Liu WU, Yingzhu WANG, Yuxin ZHENG, Xiaoting JIN

Source: 环境与职业医学, Vol 40, Iss 5, Pp 491-499 (2023)

Subject Terms: diesel particulate matter, benzo[a]pyrene, ischemia-hypoxia injury, hypoxia-inducible factor-1 alpha, oxygen sensor, anaerobic metabolism, Medicine (General), R5-920, Toxicology. Poisons, RA1190-1270

File Description: electronic resource

Relation: http://www.jeom.org/article/cn/10.11836/JEOM22416; https://doaj.org/toc/2095-9982

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The Involvement of Hypoxia in the Response of Neuroblastoma Cells to the Exposure of Atorvastatin

Authors: Ana Salomé Correia, Lara Marques, Nuno Vale

Source: Current Issues in Molecular Biology, Vol 45, Iss 4, Pp 3333-3346 (2023)

Subject Terms: drug repurposing, atorvastatin, neuroblastoma cells, hypoxia-inducible factor-1, echinomycin, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.mdpi.com/1467-3045/45/4/218; https://doaj.org/toc/1467-3037; https://doaj.org/toc/1467-3045

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Investigation of mRNA Levels of PFK-1, LDH-A, p53, and HIF-1α Genes Involved in Metabolic Reprogramming in Non-small Cell Lung Carcinoma

Authors: Fatemeh Shakeri, Mehdi Ebrahimi, Shohre Zare Karizi

Source: Journal of Kerman University of Medical Sciences, Vol 30, Iss 1, Pp 17-24 (2023)

Subject Terms: keywords keywords: lung cancer warburg effect phosphofructokinase-1 lactate dehydrogenase hypoxia-inducible factor-1, Immunologic diseases. Allergy, RC581-607, Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: https://jkmu.kmu.ac.ir/article_92132.html; https://doaj.org/toc/2008-2843

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Salvianolic acid B alleviates cartilage tissue damage in rat models with osteoarthritis

Authors: QIAN Ligang, SUN Bo, YU Bo, CHEN Kang, MA Zheng, CHEN Taoping, WANG Yunfei

Source: Jichu yixue yu linchuang, Vol 43, Iss 1, Pp 159-164 (2023)

Subject Terms: anterior cruciate ligment transection, osteoarthritis, salvianolic acid b, hypoxia-inducible factor-1, vascular endothelial growth factor, Medicine

File Description: electronic resource

Relation: http://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/1001-6325-2023-43-1-159.pdf; https://doaj.org/toc/1001-6325

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Targeting hypoxia-inducible factor-1 alpha suppresses Helicobacter pylori-induced gastric injury via attenuation of both cag-mediated microbial virulence and proinflammatory host responses

Authors: Jennifer M. Noto, M. Blanca Piazuelo, Judith Romero-Gallo, Alberto G. Delgado, Giovanni Suarez, Konstantina Akritidou, Miguel Girod Hoffman, Juan Carlos Roa, Cormac T. Taylor, Richard M. Peek

Source: Gut Microbes, Vol 15, Iss 2 (2023)

Subject Terms: Helicobacter pylori, gastric inflammation, gastric cancer, hypoxia-inducible factor-1 alpha (HIF-1α), dimethyloxalylglycine (DMOG), prolyl hydroxylase (PHD), Diseases of the digestive system. Gastroenterology, RC799-869

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Relation: https://doaj.org/toc/1949-0976; https://doaj.org/toc/1949-0984

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