Transcriptomes of the tumor-adjacent normal tissues are more informative than tumors in predicting recurrence in colorectal cancer patients

Authors: Jinho Kim, Hyunjung Kim, Min-Seok Lee, Heetak Lee, Yeon Jeong Kim, Woo Yong Lee, Seong Hyeon Yun, Hee Cheol Kim, Hye Kyung Hong, Sridhar Hannenhalli, Yong Beom Cho, Donghyun Park, Sun Shim Choi

Source: Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-15 (2023)

Subject Terms: Colorectal cancer, Normal tissues adjacent to tumors, Recurrence, Elastic net-based machine learning, Tumor-infiltrating immune cells, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/1479-5876

Access URL: https://doaj.org/article/8e84462bd82d4cb0b0c61ffa12e5ebda

Information about immune cell proportions and tumor stage improves the prediction of recurrence in patients with colorectal cancer

Authors: JungHo Kong, Jinho Kim, Donghyo Kim, Kwanghwan Lee, Juhun Lee, Seong Kyu Han, Inhae Kim, Seongsu Lim, Minhyuk Park, Seungho Shin, Woo Yong Lee, Seong Hyeon Yun, Hee Cheol Kim, Hye Kyung Hong, Yong Beom Cho, Donghyun Park, Sanguk Kim

Source: Patterns, Vol 4, Iss 6, Pp 100736- (2023)

Subject Terms: DSML 3: Development/pre-production: Data science output has been rolled out/validated across multiple domains/problems, Computer software, QA76.75-76.765

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2666389923000764; https://doaj.org/toc/2666-3899

Access URL: https://doaj.org/article/49ed47751bb248768196f1b0c67cf7da

The role of PDGFRA as a therapeutic target in young colorectal cancer patients

Authors: Tae Won Kim, Hye Kyung Hong, Chung Lee, Sunmin Kim, Woo Yong Lee, Seong Hyeon Yun, Hee Cheol Kim, Jung Wook Huh, Yoon Ah Park, Je-Gun Joung, Woong-Yang Park, Yong Beom Cho

Source: Journal of Translational Medicine, Vol 19, Iss 1, Pp 1-13 (2021)

Subject Terms: Young colorectal cancer, Biomarker, CMS, PDGFRA, Regorafenib, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/1479-5876

Access URL: https://doaj.org/article/7626f2d13b124f54a1f961b3001c0c22

Deconvolution of bulk tumors into distinct immune cell states predicts colorectal cancer recurrence

Authors: Donghyo Kim, Jinho Kim, Juhun Lee, Seong Kyu Han, Kwanghwan Lee, JungHo Kong, Yeon Jeong Kim, Woo Yong Lee, Seong Hyeon Yun, Hee Cheol Kim, Hye Kyung Hong, Yong Beom Cho, Donghyun Park, Sanguk Kim

Source: iScience, Vol 25, Iss 11, Pp 105392- (2022)

Subject Terms: Health sciences, Health informatics, Oncology, Immunology, Bioinformatics, Biocomputational method, Science

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2589004222016649; https://doaj.org/toc/2589-0042

Access URL: https://doaj.org/article/7dfa2a56699d4edfbda5bfb604a566fb

Establishment of patient‐derived organotypic tumor spheroid models for tumor microenvironment modeling

Authors: Hye Kyung Hong, Nak Hyeon Yun, Ye‐Lin Jeong, Jeehun Park, Junsang Doh, Woo Yong Lee, Yong Beom Cho

Source: Cancer Medicine, Vol 10, Iss 16, Pp 5589-5598 (2021)

Subject Terms: colorectal cancer, immune therapeutics, organotypic tumor spheroid, patient‐derived cancer model, tumor microenvironment, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2045-7634

Access URL: https://doaj.org/article/1a63e992e4414bc28aa7f85aa02a2cfd

The FBW7-MCL-1 axis is key in M1 and M2 macrophage-related colon cancer cell progression: validating the immunotherapeutic value of targeting PI3Kγ

Authors: Yeo Song Lee, Su Jeong Song, Hye Kyung Hong, Bo Young Oh, Woo Yong Lee, Yong Beom Cho

Source: Experimental and Molecular Medicine, Vol 52, Iss 5, Pp 815-831 (2020)

Subject Terms: Medicine, Biochemistry, QD415-436

File Description: electronic resource

Relation: https://doaj.org/toc/1226-3613; https://doaj.org/toc/2092-6413

Access URL: https://doaj.org/article/3ca29a930ce340edbc6c02b58212d23c

Correction: Transcriptomes of the tumor-adjacent normal tissues are more informative than tumors in predicting recurrence in colorectal cancer patients

Authors: Jinho Kim, Hyunjung Kim, Min‑Seok Lee, Heetak Lee, Yeon Jeong Kim, Woo Yong Lee, Seong Hyeon Yun, Hee Cheol Kim, Hye Kyung Hong, Sridhar Hannenhalli, Yong Beom Cho, Donghyun Park, Sun Shim Choi

Source: Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-1 (2023)

Subject Terms: Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/1479-5876

Access URL: https://doaj.org/article/4d58f45497cf4e3a9c10e3fff4c2719e

Molecular Characterization of Colorectal Signet-Ring Cell Carcinoma Using Whole-Exome and RNA Sequencing

Authors: Jae-Yong Nam, Bo Young Oh, Hye Kyung Hong, Joon Seol Bae, Tae Won Kim, Sang Yun Ha, Donghyun Park, Woo Yong Lee, Hee Cheol Kim, Seong Hyeon Yun, Yoon Ah Park, Je-Gun Joung, Woong-Yang Park, Yong Beom Cho

Source: Translational Oncology, Vol 11, Iss 4, Pp 836-844 (2018)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1936523318300998; https://doaj.org/toc/1936-5233

Access URL: https://doaj.org/article/b6e02d27913f4e618a838bf1c489c514

Identification of Sestrin3 Involved in the In vitro Resistance of Colorectal Cancer Cells to Irinotecan.

Authors: Seung Ho Choi, Hye Kyung Hong, Yong Beom Cho, Woo Yong Lee, Hae Yong Yoo

Source: PLoS ONE, Vol 10, Iss 5, p e0126830 (2015)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC4431826?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/5dd0668e98ba4731bda57b85b45b89bb

Exome and transcriptome sequencing identifies loss of PDLIM2 in metastatic colorectal cancers.

Authors: Bo Young Oh, Jeonghee Cho, Hye Kyung Hong, Joon Seol Bae, Woong-Yang Park, Je-Gun Joung, Yong Beom Cho

Source: Cancer Management & Research; Nov2017, Vol. 9, p581-589, 9p

Subject Terms: COLON cancer prognosis, RNA sequencing, METASTASIS, DNA copy number variations, PROTO-oncogenes

Predicting multi-class responses to preoperative chemoradiotherapy in rectal cancer patients.

Authors: Jungsoo Gim, Yong Beom Cho, Hye Kyung Hong, Hee Cheol Kim, Seong Hyeon Yun, Hong-Gyun Wu, Seung-Yong Jeong, Je-Gun Joung, Taesung Park, Woong-Yang Park, Woo Yong Lee, Gim, Jungsoo, Cho, Yong Beom, Hong, Hye Kyung, Kim, Hee Cheol, Yun, Seong Hyeon, Wu, Hong-Gyun, Jeong, Seung-Yong, Joung, Je-Gun, Park, Taesung

Source: Radiation Oncology; 3/22/2016, Vol. 11, p1-8, 8p

Subject Terms: RECTAL cancer patients, RECTAL cancer treatment, CHEMORADIOTHERAPY, GENE expression, DNA microarrays, RNA metabolism, ALGORITHMS, COMBINED modality therapy, GENES, RECTUM tumors, RNA, TREATMENT effectiveness, OLIGONUCLEOTIDE arrays, GENE expression profiling