Altered Synapse Stability in the Early Stages of Tauopathy

Authors: Jackson, Johanna S., Witton, Jonathan, Johnson, James D., Ahmed, Zeshan, Ward, Mark, Randall, Andrew D., Hutton, Michael L., Isaac, John T., O'Neill, Michael J., Ashby, Michael C.

Source: Cell reports. 18(13):3063-3068

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Alzheimer's Disease–Related Dementias Summit 2016: National research priorities

Authors: Corriveau, Roderick A., Koroshetz, Walter J., Gladman, Jordan T., Jeon, Sophia, Babcock, Debra, Bennett, David A., Carmichael, S. Thomas, Dickinson, Susan L.-J., Dickson, Dennis W., Emr, Marian, Fillit, Howard, Greenberg, Steven M., Hutton, Michael L., Knopman, David S., Manly, Jennifer J., Marder, Karen S., Moy, Claudia S., Phelps, Creighton H., Scott, Paul A., Seeley, William W., Sieber, Beth-Anne, Silverberg, Nina B., Sutherland, Margaret L., Taylor, Angela, Torborg, Christine L., Waddy, Salina P., Gubitz, Amelie K., Holtzman, David M.

Source: Neurology. 89(23):2381-2391

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100052075190.0x000001&indx=1&recIds=ETOCvdc_100052075190.0x000001

Conformation Determines the Seeding Potencies of Native and Recombinant Tau Aggregates

Authors: Falcon, Benjamin, Cavallini, Annalisa, Angers, Rachel, Glover, Sarah, Murray, Tracey K., Barnham, Luanda, Jackson, Samuel, O'Neill, Michael J., Isaacs, Adrian M., Hutton, Michael L., Szekeres, Philip G., Goedert, Michel, Bose, Suchira

Source: In Journal of Biological Chemistry 9 January 2015 290(2):1049-1065

A Plaque-Specific Antibody Clears Existing β-amyloid Plaques in Alzheimer's Disease Mice

Authors: DeMattos, Ronald B., Lu, Jirong, Tang, Ying, Racke, Margaret M., DeLong, Cindy A., Tzaferis, John A., Hole, Justin T., Forster, Beth M., McDonnell, Peter C., Liu, Feng, Kinley, Robert D., Jordan, William H., Hutton, Michael L.

Source: In Neuron 6 December 2012 76(5):908-920

Passive Immunization with Anti-Tau Antibodies in Two Transgenic Models: REDUCTION OF TAU PATHOLOGY AND DELAY OF DISEASE PROGRESSION

Authors: Chai, Xiyun, Wu, Su, Murray, Tracey K., Kinley, Robert, Cella, Claire V., Sims, Helen, Buckner, Nicola, Hanmer, Jenna, Davies, Peter, O'Neill, Michael J., Hutton, Michael L., Citron, Martin

Source: In Journal of Biological Chemistry 30 September 2011 286(39):34457-34467

Imbalance in the response of pre- and post-synaptic components to amyloidopathy

Authors: Stephen, Terri-Leigh, Tamagnini, Francesco, Piegsa, Judith, Sung, Katherine, Harvey, Joshua, Oliver-Evans, Alice, Murray, Tracey K., Ahmed, Zeshan, Hutton, Michael L., Randall, Andrew, O'Neill, Michael J., Jackson, Johanna S.

Source: Scientific reports. 9(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100131425021.0x000001&indx=1&recIds=ETOCvdc_100131425021.0x000001

Evidence for an association between KIBRA and late-onset Alzheimer's disease

Authors: Corneveaux, Jason J., Liang, Winnie S., Reiman, Eric M., Webster, Jennifer A., Myers, Amanda J., Zismann, Victoria L., Joshipura, Keta D., Pearson, John V., Hu-Lince, Diane, Craig, David W., Coon, Keith D., Dunckley, Travis, Bandy, Daniel, Lee, Wendy, Chen, Kewei, Beach, Thomas G., Mastroeni, Diego, Grover, Andrew, Ravid, Rivka, Sando, Sigrid B., Aasly, Jan O., Heun, Reinhard, Jessen, Frank, Kölsch, Heike, Rogers, Joseph, Hutton, Michael L., Melquist, Stacey, Petersen, Ron C., Alexander, Gene E., Caselli, Richard J., Papassotiropoulos, Andreas, Stephan, Dietrich A., Huentelman, Matthew J.

Source: In Neurobiology of Aging June 2010 31(6):901-909

Accelerated Lipofuscinosis and Ubiquitination in Granulin Knockout Mice Suggest a Role for Progranulin in Successful Aging

Authors: Ahmed, Zeshan, Sheng, Hong, Xu, Ya-fei, Lin, Wen-Lang, Innes, Amy E., Gass, Jennifer, Yu, Xin, Hou, Harold, Chiba, Shuichi, Yamanouchi, Keitaro, Leissring, Malcolm, Petrucelli, Leonard, Nishihara, Masugi, Hutton, Michael L., McGowan, Eileen, Dickson, Dennis W., Lewis, Jada

Source: In The American Journal of Pathology 2010 177(1):311-324

Mimicking Aspects of Frontotemporal Lobar Degeneration and Lou Gehrig's Disease in Rats via TDP-43 Overexpression

Authors: Tatom, Jason B, Wang, David B, Dayton, Robert D, Skalli, Omar, Hutton, Michael L, Dickson, Dennis W, Klein, Ronald L

Source: In Molecular Therapy April 2009 17(4):607-613

Detecting and treating dementia

Clinical-pathologic study of biomarkers in FTDP-17 (PPND family with N279K tau mutation)

Authors: Arvanitakis, Zoe, Witte, Robert J., Dickson, Dennis W., Tsuboi, Yoshio, Uitti, Ryan J., Slowinski, Jerzy, Hutton, Michael L., Lin, Siong-Chi, Boeve, Bradley F., Cheshire, William P., Pooley, Robert A., Liss, Julie M., Caviness, John N., Strongosky, Audrey J., Wszolek, Zbigniew K.

Source: In Parkinsonism and Related Disorders 2007 13(4):230-239

Identification of the Genetic Basis for Complex Disorders by Use of Pooling-Based Genomewide Single-Nucleotide–Polymorphism Association Studies

Authors: Pearson, John V., Huentelman, Matthew J., Halperin, Rebecca F., Tembe, Waibhav D., Melquist, Stacey, Homer, Nils, Brun, Marcel, Szelinger, Szabolcs, Coon, Keith D., Zismann, Victoria L., Webster, Jennifer A., Beach, Thomas, Sando, Sigrid B., Aasly, Jan O., Heun, Reinhard, Jessen, Frank, Kölsch, Heike, Tsolaki, Magdalini, Daniilidou, Makrina, Reiman, Eric M., Papassotiropoulos, Andreas, Hutton, Michael L., Stephan, Dietrich A., Craig, David W.

Source: In The American Journal of Human Genetics 2007 80(1):126-139

DETECTING AND TREATING DEMENTIA

The Effect of tau genotype on clinical features in FTDP-17

Authors: Baba, Yasuhiko, Tsuboi, Yoshio, Baker, Matthew C., Uitti, Ryan J., Hutton, Michael L., Dickson, Dennis W., Farrer, Matthew, Putzke, John D., Woodruff, Bryan K., Ghetti, Bernardino, Murrell, Jill R., Boeve, Bradley F., Petersen, Ronald C., Verpillat, Patrice, Brice, Alexis, Delisle, Marie-Bernadette, Rascol, Oliver, Arima, Kunimasa, Dysken, Maurice W., Yasuda, Minoru, Kobayashi, Tomonori, Sunohara, Nobuhiko, Komure, Osamu, Kuno, Sadako, Sperfeld, Anne D., Stoppe, Gabriela, Kohlhase, Jürgen, Pickering-Brown, Stuart, Neary, David, Bugiani, Orso, Wszolek, Zbigniew K.

Source: In Parkinsonism and Related Disorders 2005 11(4):205-208

Increase in tau tyrosine phosphorylation correlates with the formation of tau aggregates

Authors: Vega, Irving E., Cui, Li, Propst, Josh A., Hutton, Michael L., Lee, Gloria, Yen, Shu-Hui

Source: In Molecular Brain Research 2005 138(2):135-144

Heredofamilial Brain Calcinosis Syndrome

Authors: Baba, Yasuhiko, Broderick, Daniel F., Uitti, Ryan J., Hutton, Michael L., Wszolek, Zbigniew K.

Source: In Mayo Clinic Proceedings 2005 80(5):641-651

APOE ε4 lowers age at onset and is a high risk factor for Alzheimer's disease; A case control study from central Norway

Authors: Saltvedt Ingvild, Sletvold Olav, Hutton Michael L, Cannon Ashley, Melquist Stacey, Sando Sigrid B, White Linda R, Lydersen Stian, Aasly Jan O

Source: BMC Neurology, Vol 8, Iss 1, p 9 (2008)

Subject Terms: Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: http://www.biomedcentral.com/1471-2377/8/9; https://doaj.org/toc/1471-2377

Access URL: https://doaj.org/article/069f42eace5841d394d7046ceb5ffeb1

Progranulin in frontotemporal lobar degeneration and neuroinflammation

Authors: Hutton Michael L, Mackenzie Ian RA, Ahmed Zeshan, Dickson Dennis W

Source: Journal of Neuroinflammation, Vol 4, Iss 1, p 7 (2007)

Subject Terms: Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: http://www.jneuroinflammation.com/content/4/1/7; https://doaj.org/toc/1742-2094

Access URL: https://doaj.org/article/037209a55cf44bd599c6b5cad81e3184

Analysis of IFT74 as a candidate gene for chromosome 9p-linked ALS-FTD

Authors: Rogaeva Ekaterina, Hutton Michael L, Adamson Jennifer, Wassermann Eric M, Huey Edward D, Holtzman David M, Fung Hon, Chiò Adriano, Pickering-Brown Stuart, Berger Stephen, Greenway Matthew J, Greggio Elisa, Cairns Nigel J, Cookson Mark R, Jain Shushant, Schymick Jennifer, Momeni Parastoo, St George-Hyslop Peter, Rothstein Jeffrey D, Hardiman Orla, Grafman Jordan, Singleton Andrew, Hardy John, Traynor Bryan J

Source: BMC Neurology, Vol 6, Iss 1, p 44 (2006)

Subject Terms: Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: http://www.biomedcentral.com/1471-2377/6/44; https://doaj.org/toc/1471-2377

Access URL: https://doaj.org/article/ddfa16b0fe0040538ac1b5136221f70f

DEVELOPING IN VIVO MODELS OF TAU PROPAGATION WHICH ARE RELEVANT TO HUMAN DISEASE PATHOGENESIS AND APPLICABLE TO PRE-CLINICAL DRUG DISCOVERY

Authors: Ahmed, Zeshan, Cooper, Jane, Kerridge, Caroline, Vargova, Tereza, Fisher, Alice, Murray, Tracey K., Ward, Mark, Meftah, Soraya, Cavallini, Annalisa, Goedert, Michel, Hutton, Michael L., Bose, Suchira, O'Neill, Michael J.

Source: Alzheimer's & dementia. 13(7):P906-P906

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100061748913.0x000001&indx=1&recIds=ETOCvdc_100061748913.0x000001