Safety and activity of CTX130, a CD70-targeted allogeneic CRISPR-Cas9-engineered CAR T-cell therapy, in patients with relapsed or refractory T-cell malignancies (COBALT-LYM): a single-arm, open-label, phase 1, dose-escalation study

Authors: Iyer, Swaminathan P ^{a, †, *}, Sica, R Alejandro ^{c, †}, Ho, P Joy ^d, Prica, Anca ^e, Zain, Jasmine ^f, Foss, Francine M ^g, Hu, Boyu ^h, Beitinjaneh, Amer ⁱ, Weng, Wen-Kai ^j, Kim, Youn H ^k, Khodadoust, Michael S ^l, Huen, Auris O ^b, Williams, Leah M ^m, Ma, Anna ^m, Huang, Elaine ^m, Ganpule, Avanti ^m, Nagar, Shashwat Deepali ^m, Sripakdeevong, Parin ^m, Cullingford, Erika L ^m, Karnik, Sushant ^m, Dequeant, Mary-Lee ^m, Patel, Janki N ^m, He, Xinyi Shirley ^m, Li, Ziliang ^m, He, Qiuling Ally ^m, Mendonez, Joy H ^m, Keegan, Alissa ^m, Horwitz, Steven M ⁿ

Source: In The Lancet Oncology January 2025 26(1):110-122

Radiotherapy in the treatment of primary cutaneous CD4+ small/medium T‐cell lymphoproliferative disorder.

Authors: Wu, Susan Y., Damron, Ethan P., Xu, Jie, Fang, Penny Q., Dai, Julia, Nair, Ranjit, Malpica Castillo, Luis E., Fayad, Luis E., Torres‐Cabala, Carlos A., Medeiros, L. Jeffrey, Vega, Francisco, Miranda, Roberto N., Duvic, Madeleine, Pinnix, Chelsea C., Dabaja, Bouthaina S., Iyer, Swaminathan P., Huen, Auris O., Gunther, Jillian R.

Source: International Journal of Dermatology; Feb2025, Vol. 64 Issue 2, p385-389, 5p

Subject Terms: RADIOTHERAPY, CUTANEOUS T-cell lymphoma, INTENSITY modulated radiotherapy, HAZARDS, DISEASE remission, THERAPEUTICS, PATIENT selection

Company/Entity: UNIVERSITY of Texas M.D. Anderson Cancer Center

Methicillin-resistant Staphylococcus aureus (MRSA) is an important pathogen in erythrodermic cutaneous T-cell lymphoma (CTCL) patients

Authors: Emge, Drew A., Bassett, Roland L., Duvic, Madeleine, Huen, Auris O.

Source: Archives of dermatological research. 312(4):283-288

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100168069896.0x000001&indx=1&recIds=ETOCvdc_100168069896.0x000001

Qol-P-04 - Health-related quality of life effect of mogamulizumab by patient blood involvement

Authors: Zinzani, Pier Luigi, Ortiz-Romero, Pablo, Lima, Margarida, Huen, Auris O.

Source: In European Journal of Cancer October 2021 156 Supplement 1:S65-S66

Safety of Concurrent Radiation Therapy With Brentuximab Vedotin in the Treatment of Lymphoma

Authors: Wu, Susan Y., Fang, Penny Q., Wang, Ethan B., Ahmed, Sairah, Duvic, Madeleine, Jain, Preetesh, Castillo, Luis E. Malpica, Nair, Ranjit, Steiner, Raphael E., Strati, Paolo, Huen, Auris O., Iyer, Swaminathan P., Pinnix, Chelsea C., Dabaja, Bouthaina S., Gunther, Jillian R.

Source: In Advances in Radiation Oncology November-December 2023 8(6)

Brentuximab Vedotin for Patients With Refractory Lymphomatoid PapulosisAn Analysis of Phase 2 Results

Authors: Lewis, Daniel J., Talpur, Rakhshandra, Huen, Auris O.

Source: JAMA Dermatology. 153(12):1302-1306

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN633141070&indx=1&recIds=ETOCRN633141070

The Great Mimicker: Forgotten but not Gone

Authors: Fenner, Blayne E. ^{a, ⁎}, Burningham, Kevin M. ^b, Thomas, Jamael L. ^c, Kelly, Brent C. ^d, Huen, Auris O. ^e, Tyring, Stephen K. ^{b, c}

Source: In American Journal of Medicine Open June 2025 13

Health-related quality of life effect of mogamulizumab by patient blood involvement

Authors: Zinzani, Pier Luigi, Ortiz-Romero, Pablo, Lima, Margarida, Huen, Auris O.

Source: European journal of cancer. 156(S1):S65-S66

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100144626544.0x000001&indx=1&recIds=ETOCvdc_100144626544.0x000001

Complete Response to tenalisib and romidepsin with long-term maintenance using tenalisib monotherapy in a patient with relapsed and refractory sézary syndrome.

Authors: Nguyen, Christopher N., Iyer, Swaminathan P., Duvic, Madeleine, Barde, Prajak J., Nair, Ajit, Routhu, Kasi Viswanath, Huen, Auris O.

Source: Investigational New Drugs; Apr2023, Vol. 41 Issue 2, p350-355, 6p

Subject Terms: THERAPEUTIC use of antineoplastic agents, MYCOSIS fungoides, DISEASE relapse, SEZARY syndrome, ENZYME inhibitors, DISEASE remission, CUTANEOUS T-cell lymphoma

Management strategies and survival in cutaneous B-cell lymphoma: A population based study

Authors: Lauck, Kyle, Ahmad, Areebah S., Nguyen, Quoc-Bao D., Yang, Zixi, Kundu, Suprateek, Huen, Auris O.

Source: In JAAD International December 2023 13:28-29

Preliminary Safety, Pharmacokinetics, Pharmacodynamics and Clinical Activity of KT-333, a Targeted Protein Degrader of STAT3, in Patients with Relapsed or Refractory Lymphomas, Large Granular Lymphocytic Leukemia, and Solid Tumors

Authors: Shastri, Aditi, Feldman, Eric J, Starodub, Alexander N, Feldman, Tatyana, Rodriguez, Cristina P, Epstein-Peterson, Zachary D., Stevens, Don A., Olszewski, Adam J, Huen, Auris O, Porcu, Pierluigi, Reneau, John C, Barta, Stefan K., Marchi, Enrica, Mattour, Ahmad H, Pinter-Brown, Lauren C., Perea, Rachelle, Donohue, Sean, Dey, Joyoti, Agarwal, Sagar, Karnik, Rahul, Gollerkeri, Ashwin, Gollob, Jared, Smith, Stephen D

Source: In Blood 2 November 2023 142 Supplement 1:3081-3081

Cutaneous adverse events in 155 patients with metastatic melanoma consecutively treated with anti‐CTLA4 and anti‐PD1 combination immunotherapy: Incidence, management, and clinical benefit.

Authors: Patel, Anisha B., Farooq, Sahira, Welborn, Macartney, Amaria, Rodabe N., Chon, Susan Y., Diab, Adi, Glitza Oliva, Isabella C., Huen, Auris O., Li, Shirley Q., Nelson, Kelly C., Pacha, Omar, Patel, Sapna P., Rapini, Ronald P., Tawbi, Hussein A., Wong, Michael K., McQuade, Jennifer, Davies, Michael A., Haydu, Lauren E.

Source: Cancer (0008543X); Mar2022, Vol. 128 Issue 5, p975-983, 9p

Subject Terms: MELANOMA, DRUG side effects, ECZEMA, IMMUNOTHERAPY

Biologic therapies for checkpoint inhibitor-induced cutaneous toxicities: a single-institution study of 17 consecutively treated patients.

Authors: Lo, Jonathan J., Heberton, Meghan M., Pacha, Omar, Huen, Auris O., Patel, Anisha B.

Source: Supportive Care in Cancer; Feb2022, Vol. 30 Issue 2, p989-994, 6p

Subject Terms: DERMATOTOXICOLOGY, BIOTHERAPY, ELECTRONIC health records, PATIENTS' attitudes, DRUG side effects, SKIN diseases, SKIN, RETROSPECTIVE studies, TUMORS

Aggressive primary cutaneous anaplastic large cell lymphoma with massive bilateral upper limb involvement at relapse

Authors: Nguyen, Christopher N., Iyer, Swaminathan P., Miranda, Roberto N., Torres-Cabala, Carlos A., Curry, Jonathan L., Fang, Penny, Thomas, Valencia D., Huen, Auris O.

Source: In JAAD Case Reports November 2021 17:34-37

Comparison of in vitro Activity of Two New Triazoles, Voriconazole and SCH-56592, and Fluconazole Against Candida albicans by Time-Kill Methodology.

Authors: Burgess, David S.¹ burgessd@uthscsa.edu, Huen, Auris O.¹, Hastings, Rhonda W.²

Source: Journal of Infectious Disease Pharmacotherapy. 2000, Vol. 4 Issue 3, p21. 14p.

Subject Terms: *COMPARATIVE studies, *TRIAZOLES, *CANDIDA albicans, *COMMUNICABLE disease treatment, *MYCOSES, *MEDICAL research

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Successful treatment of cutaneous adult T-cell leukemia/lymphoma with imiquimod

Authors: Messer, Alison, Brown, Ashley E., Pacha, Omar, Boddu, Prajwal, Geppner, Alexis, Kadia, Tapan M., Huen, Auris O.

Source: In JAAD Case Reports November 2019 5(11):979-981

Unusual presentation of Kaposi sarcoma in an HIV-negative woman.

Authors: Limmer, Allison L., Park, Katherine E., Patel, Anisha B., Huen, Auris O.

Source: Dermatology Online Journal; 2020, Vol. 26 Issue 4, p1-3, 3p

Subject Terms: KAPOSI'S sarcoma, HIV, IMMUNOCOMPROMISED patients, SQUAMOUS cell carcinoma, BIOPSY

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Paraneoplastic microscopic polyangiitis presenting after thymectomy

Authors: Tracey, Elisabeth H., Huen, Auris O., Sreih, Antoine G., Evans, Tracey, Kobrin, Sidney, Rubin, Adam I., Rosenbach, Misha

Source: In JAAD Case Reports March 2016 2(2):153-155