Targeting cyclin-dependent kinases: From pocket specificity to drug selectivity

Authors: Huang, Yaoguang, Liu, Wenwu, Zhao, Changhao, Shi, Xiaoyu, Zhao, Qingchun, Jia, Jingming, Wang, Anhua

Source: In European Journal of Medicinal Chemistry 5 September 2024 275

The ADAM17 inhibitor ZLDI-8 sensitized hepatocellular carcinoma cells to sorafenib through Notch1-integrin β-talk

Authors: Xu, Chang, Gao, Xudong, Ren, Tianshu, Geng, Hefeng, Yang, Kaisi, Huang, Yaoguang, Zhang, Weige, Hou, Shanbo, Song, Aigang, Zhang, Yingshi, Zhao, Qingchun

Source: In Pharmacological Research May 2024 203

Influence of the interfacial thermal resistance of a gadolinium/copper bimetal composite on solid-state magnetic refrigeration

Alternate Title: Influence de la résistance thermique d'interface d'un composite bimétallique gadolinium/cuivre sur le froid magnétique à l'état solide (French)

Authors: Lu, Biwang, Huang, Yaoguang, Huang, Jiaohong, Ma, Zhihong, Wang, Jing, He, Jing

Source: In International Journal of Refrigeration September 2023 153:90-98

Structural characterization and anti-inflammatory activity of a novel neutral polysaccharide isolated from Smilax glabra Roxb.

Authors: Huang, Yaoguang ^{a, 1}, Ye, Yongli ^{a, 1}, Xu, Deping ^a, Ji, Jian ^a, Sun, Jiadi ^a, Xu, Mengqi ^a, Xia, Bangen ^b, Shen, Hongfang ^b, Xia, Ruowei ^b, Shi, Wenqin ^b, Sun, Xiulan ^{a, ⁎}

Source: In International Journal of Biological Macromolecules 15 April 2023 234

Development and structure-activity relationship of tacrine derivatives as highly potent CDK2/9 inhibitors for the treatment of cancer

Authors: Wu, Limeng, Liu, Wenjie, Huang, Yaoguang, Zhu, Chengze, Ma, Qun, Wu, Qiong, Tian, Liting, Feng, Xiangling, Liu, Mingyue, Wang, Nan, Xu, Xiangbo, Liu, Xin, Xu, Chang, Qiu, Jingsong, Xu, Zihua, Liu, Wenwu, Zhao, Qingchun

Source: In European Journal of Medicinal Chemistry 15 November 2022 242

Polygonatum sibiricum polysaccharide extract relieves FB1-induced neurotoxicity by reducing oxidative stress and mitochondrial damage in Caenorhabditis elegans

Authors: Zhang, Xiaojuan, Ye, Yongli, Sun, Jiadi, Xu, Yida, Huang, Yaoguang, Wang, Jia-Sheng, Tang, Lili, Ji, Jian, Chen, Bi-yan, Sun, Xiulan

Source: In Food Bioscience October 2022 49

Discovery of novel and potent tacrine derivatives as CDK2 inhibitorsElectronic supplementary information (ESI) available: Supplementary data related to this article can be found via the internet. 1H-NMR and 13C-NMR spectra of the intermediates and target compounds. See DOI: https://doi.org/10.1039/d2nj03591j

Authors: Huang, Yaoguang, Li, Deping, Xu, Chang, Zhu, Chengze, Wu, Limeng, Shen, Meiling, Li, Yue, Jiang, Xiaowen, Liu, Wenwu, Zhao, Qingchun, Ren, Tianshu

Source: New journal of chemistry. 46(43):20972-20984

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100168931228.0x000001&indx=1&recIds=ETOCvdc_100168931228.0x000001

Novel tacrine derivatives as potential CDK9 inhibitors with low cholinesterase inhibitory properties: design, synthesis, and biological evaluationElectronic supplementary information (ESI) available. See DOI: https://doi.org/10.1039/d2nj03667c

Authors: Liu, Wenwu, Huang, Yaoguang, Wu, Limeng, Liu, Wenjie, Jiang, Xiaowen, Xu, Zihua, Zhao, Qingchun

Source: New journal of chemistry. 46(40):19342-19356

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100162952675.0x000001&indx=1&recIds=ETOCvdc_100162952675.0x000001

Discovery of novel tacrine derivatives as potent antiproliferative agents with CDKs inhibitory property

Authors: Liu, Wenwu, Wu, Limeng, Li, Deping, Huang, Yaoguang, Liu, Mingyue, Liu, Wenjie, Tian, Caizhi, Liu, Xin, Jiang, Xiaowen, Hu, Xiaolong, Gao, Xudong, Xu, Zihua, Lu, Hongyuan, Zhao, Qingchun

Source: In Bioorganic Chemistry September 2022 126

Discovery of novel benzofuro[3,2-b]quinoline derivatives as dual CDK2/Topo I inhibitors

Authors: Huang, Yaoguang, Liu, Wenwu, Huang, Shuoqi, Li, Deping, Xu, Chang, Jiang, Xiaowen, Liu, Mingyue, Liu, Xin, Zhu, Chengze, Wu, Limeng, Chen, Huanhua, Xu, Zihua, Zhao, Qingchun

Source: In Bioorganic Chemistry September 2022 126

Discovery of novel β-carboline derivatives as selective AChE inhibitors with GSK-3β inhibitory property for the treatment of Alzheimer's disease

Authors: Liu, Wenwu, Liu, Xin, Liu, Wenjie, Gao, Yaping, Wu, Limeng, Huang, Yaoguang, Chen, Huanhua, Li, Deping, Zhou, Lijun, Wang, Nan, Xu, Zihua, Jiang, Xiaowen, Zhao, Qingchun

Source: In European Journal of Medicinal Chemistry 5 February 2022 229

In Utero Exposure to Fine Particles Decreases Early Birth Weight of Rat Offspring and TLR4/NF-κB Expression in Lungs

Authors: Tang, Wenting, Li, Zhongjun, Huang, Yaoguang, Du, Lili, Wen, Chuangyu, Sun, Wen, Yu, Zhiqiang, Huang, Suran, Chen, Dunjin

Source: Chemical research in toxicology. 34(1):47-53

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN631521317&indx=1&recIds=ETOCRN631521317

How two-child policy affects cesarean section in women with advanced maternal age (AMA): using the Robson classification system.

Authors: Tang, Wenting, Zeng, Daidi, Wu, Wanhua, Wu, Shuzhen, Ou, Yijing, Huang, Yaoguang, Xiao, Lijuan, Huang, Suran, Li, Zhongjun

Source: BMC Pregnancy & Childbirth; 10/3/2024, Vol. 24 Issue 1, p1-7, 7p

Subject Terms: MATERNAL age, MULTIPLE birth, GESTATIONAL age, AGE groups, CESAREAN section

Plastic failure zone characteristics and stability control technology of roadway in the fault area under non-uniformly high geostress: A case study from Yuandian Coal Mine in Northern Anhui Province, China

Authors: Huang Yaoguang, Zhao Aining, Zhang Tianjun, Guo Weibin

Source: Open Geosciences, Vol 12, Iss 1, Pp 406-424 (2020)

Subject Terms: elastic–plastic analysis, plastic failure, non-uniformly high geostress, fault area, roadway support, Geology, QE1-996.5

File Description: electronic resource

Relation: https://doaj.org/toc/2391-5447

Access URL: https://doaj.org/article/55284179935a4590af7d05c31fee78c6

Cryo-EM Structure and Assembly of an Extracellular Contractile Injection System

Authors: Jiang, Feng, Li, Ningning, Wang, Xia, Cheng, Jiaxuan, Huang, Yaoguang, Yang, Yun, Yang, Jianguo, Cai, Bin, Wang, Yi-Ping, Jin, Qi, Gao, Ning

Source: In Cell 4 April 2019 177(2):370-383

Shear Strength and Re-Failure Characteristics of Intact Red Sandstone and Grouting-Reinforced Body of Fractured Red Sandstone under Different Shear Angles.

Authors: Huang, Yaoguang¹ (AUTHOR) hyg85@xust.edu.cn, Yang, Wanxia¹ (AUTHOR), Zhao, Aining¹ (AUTHOR), Guo, Weibin² (AUTHOR)

Source: Minerals (2075-163X). Dec2022, Vol. 12 Issue 12, p1580. 16p.

Subject Terms: *SHEAR strength, *SANDSTONE, *SHEAR (Mechanics), *ROCK deformation, *ACOUSTIC emission

Discovery of novel benzofuro[3, 2-b]quinoline derivatives as dual CDK2/Topo I inhibitors

Authors: Huang, Yaoguang, Liu, Wenwu, Huang, Shuoqi, Li, Deping, Xu, Chang, Jiang, Xiaowen, Liu, Mingyue, Liu, Xin, Zhu, Chengze, Wu, Limeng, Chen, Huanhua, Xu, Zihua, Zhao, Qingchun

Source: Bioorganic chemistry. 126

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100171435716.0x000001&indx=1&recIds=ETOCvdc_100171435716.0x000001

Discovery of novel α‐carboline derivatives as glycogen synthase kinase‐3β inhibitors for the treatment of Alzheimer's disease

Authors: Chen, Huanhua, Yu, Chong, Liu, Wenjie, Zhu, Chengze, Jiang, Xiaowen, Xu, Chang, Liu, Wenwu, Huang, Yaoguang, Xu, Zihua, Zhao, Qingchun

Source: Archiv der Pharmazie. 355(10)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100162413853.0x000001&indx=1&recIds=ETOCvdc_100162413853.0x000001

Spatial Distribution Characteristics of Plastic Failure and Grouting Diffusion within Deep Roadway Surrounding Rock under Three-Dimensional Unequal Ground Stress and Its Application.

Authors: Huang, Yaoguang¹ (AUTHOR) 19201106032@stu.xust.edu.cn, Yang, Wanxia¹ (AUTHOR) 21201106038@stu.xust.edu.cn, Li, Yangyang¹ (AUTHOR), Guo, Weibin² (AUTHOR) guoweibin@xust.edu.cn

Source: Minerals (2075-163X). Mar2022, Vol. 12 Issue 3, p296. 21p.

Subject Terms: *GROUTING, *PLASTICS, *ROADS, *AXIAL stresses, *COAL mining

Discovery of novel harmine derivatives as GSK‐3β/DYRK1A dual inhibitors for Alzheimer's disease treatment.

Authors: Qiu, Jingsong, Feng, Xiangling, Chen, Huanhua, Liu, Wenwu, Liu, Wenjie, Wu, Limeng, Gao, Xudong, Liu, Yanfang, Huang, Yaoguang, Gong, Hao, Qi, Yiming, Xu, Zihua, Zhao, Qingchun

Source: Archiv der Pharmazie; Feb2024, Vol. 357 Issue 2, p1-18, 18p