Preclinical models of soft tissue sarcomas – generation and applications to enhance translational research

Authors: Pasquali, Sandro ^{a, 1}, Moura, David S. ^{b, c, d, 1}, Danks, Molly R. ^{e, 1}, Manasterski, Piotr J. ^{e, 1}, Zaffaroni, Nadia ^a, Stacchiotti, Silvia ^a, Mondaza-Hernandez, Jose L. ^{b, c, d}, Kerrison, William G.J. ^f, Martin-Broto, Javier ^{b, c, d}, Huang, Paul H. ^f, Brunton, Valerie G. ^{e, ⁎}

Source: In Critical Reviews in Oncology / Hematology March 2025 207

A CT-based radiomics classification model for the prediction of histological type and tumour grade in retroperitoneal sarcoma (RADSARC-R): a retrospective multicohort analysis

Authors: Arthur, Amani ^*, Orton, Matthew R ^*, Emsley, Robby, Vit, Sharon, Kelly-Morland, Christian, Strauss, Dirk, Lunn, Jason, Doran, Simon, Lmalem, Hafida, Nzokirantevye, Axelle, Litiere, Saskia, Bonvalot, Sylvie, Haas, Rick, Gronchi, Alessandro, Van Gestel, Dirk, Ducassou, Anne, Raut, Chandrajit P, Meeus, Pierre, Spalek, Mateusz, Hatton, Matthew, Le Pechoux, Cecile, Thway, Khin, Fisher, Cyril, Jones, Robin, Huang, Paul H ^†, Messiou, Christina ^{†, *}

Source: In The Lancet Oncology November 2023 24(11):1277-1286

Molecular profiling in desmoplastic small round cell tumours

Authors: Tam, Yuen Bun, Jones, Robin L., Huang, Paul H.

Source: In International Journal of Biochemistry and Cell Biology April 2023 157

The biology and treatment of leiomyosarcomas

Authors: Kerrison, William G.J., Thway, Khin, Jones, Robin L., Huang, Paul H.

Source: In Critical Reviews in Oncology / Hematology April 2023 184

Amivantamab for the treatment of EGFR exon 20 insertion mutant non-small cell lung cancer

Authors: Vyse, Simon, Huang, Paul H

Source: Expert review of anticancer therapy. 22(1):3-16

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100139233137.0x000001&indx=1&recIds=ETOCvdc_100139233137.0x000001

KIT Exon 9-Mutated Gastrointestinal Stromal Tumours: Biology and Treatment

Authors: Napolitano, Andrea, Thway, Khin, Smith, Myles J., Huang, Paul H., Jones, Robin L.

Source: Chemotherapy. 67(2):81-90

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100151470458.0x000001&indx=1&recIds=ETOCvdc_100151470458.0x000001

Machine learning for rhabdomyosarcoma histopathology

Authors: Frankel, Arthur O., Lathara, Melvin, Shaw, Celine Y., Wogmon, Owen, Jackson, Jacob M., Clark, Mattie M., Eshraghi, Navah, Keenen, Stephanie E., Woods, Andrew D., Purohit, Reshma, Ishi, Yukitomo, Moran, Nirupama, Eguchi, Mariko, Ahmed, Farhat Ul Ain, Khan, Sara, Ioannou, Maria, Perivoliotis, Konstantinos, Li, Pin, Zhou, Huixia, Alkhaledi, Ahmad, Davis, Elizabeth J., Galipeau, Danielle, Randall, R.L., Wozniak, Agnieszka, Schoffski, Patrick, Lee, Che-Jui, Huang, Paul H., Jones, Robin L., Rubin, Brian P., Darrow, Morgan, Srinivasa, Ganapati, Rudzinski, Erin R., Chen, Sonja, Berlow, Noah E., Keller, Charles

Source: In Modern Pathology September 2022 35(9):1193-1203

The Cancer Genome Atlas: Impact and Future Directions in Sarcoma

Authors: Burns, Jessica, Brown, Jeffrey M., Jones, Kevin B., Huang, Paul H.

Source: In Surgical Oncology Clinics of North America July 2022 31(3):559-568

The perplexing role of immuno-oncology drugs in osteosarcoma

Authors: Smrke, Alannah, Tam, Yuen B., Anderson, Peter M., Jones, Robin L., Huang, Paul H.

Source: In Journal of Bone Oncology December 2021 31

Proteomic profiling of soft tissue sarcomas with SWATH mass spectrometry

Authors: Milighetti, Martina, Krasny, Lukas, Lee, Alex T.J., Morani, Gabriele, Szecsei, Cornelia, Chen, Yingtong, Guljar, Nafia, McCarthy, Frank, Wilding, Christopher P., Arthur, Amani, Fisher, Cyril, Judson, Ian, Thway, Khin, Cheang, Maggie C.U., Jones, Robin L., Huang, Paul H.

Source: In Journal of Proteomics 15 June 2021 241

Gastrointestinal leiomyosarcoma demonstrate a predilection for distant recurrence and poor response to systemic treatments

Authors: Smrke, Alannah, Benson, Charlotte, Strauss, Dirk C., Hayes, Andrew J., Thway, Khin, Hallin, Magnus, Fisher, Cyril, Messiou, Christina, Huang, Paul H., Jones, Robin L., Smith, Myles J.

Source: European journal of surgical oncology. 47(10):2595-2601

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100138947361.0x000001&indx=1&recIds=ETOCvdc_100138947361.0x000001

Next-generation sequencing for the management of sarcomas with no known driver mutations

Authors: Vyse, Simon, Thway, Khin, Huang, Paul H., Jones, Robin L.

Source: Current opinion in oncology. 33(4):315-322

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100121662951.0x000001&indx=1&recIds=ETOCvdc_100121662951.0x000001

Data-independent acquisition mass spectrometry (DIA-MS) for proteomic applications in oncology

Authors: Krasny, Lukas, Huang, Paul H.

Source: Molecular omics. 17(1):29-42

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100116496256.0x000001&indx=1&recIds=ETOCvdc_100116496256.0x000001

Advances in the proteomic profiling of the matrisome and adhesome

Authors: Krasny, Lukas, Huang, Paul H.

Source: Expert review of proteomics. 18(9):781-794

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100133868411.0x000001&indx=1&recIds=ETOCvdc_100133868411.0x000001

Rare epidermal growth factor receptor (EGFR) mutations in non-small cell lung cancer

Authors: Harrison, Peter T., Vyse, Simon, Huang, Paul H.

Source: In Seminars in Cancer Biology April 2020 61:167-179

Think zebras: challenges and opportunities for treating rare cancers

Authors: Behjati, Sam ^{1, 2, 3, ⁎}, Boehm, Jesse S. ^{4, 5, ⁎}, Dun, Matthew D. ^{6, 7, 8, ⁎}, Fröhling, Stefan ^{9, 10, 11, ⁎}, Huang, Paul H. ^{12, ⁎}, Jabado, Nada ^{13, ⁎}, Li, Ning ^{14, ⁎}, Robles-Espinoza, Carla Daniela ^{1, 15, ⁎}

Source: In Trends in Cancer February 2025 11(2):75-80

Fibroblastic Reticular Cells Control Conduit Matrix Deposition during Lymph Node Expansion

Authors: Martinez, Victor G., Pankova, Valeriya, Krasny, Lukas, Singh, Tanya, Makris, Spyridon, White, Ian J., Benjamin, Agnesska C., Dertschnig, Simone, Horsnell, Harry L., Kriston-Vizi, Janos, Burden, Jemima J., Huang, Paul H., Tape, Christopher J., Acton, Sophie E.

Source: In Cell Reports 26 November 2019 29(9):2810-2822

Opportunities and Challenges in Soft Tissue Sarcoma Risk Stratification in the Era of Personalised Medicine.

Authors: Chowdhury, Avirup, Thway, Khin, Pasquali, Sandro, Callegaro, Dario, Gronchi, Alessandro, Jones, Robin L., Huang, Paul H.

Source: Current Treatment Options in Oncology; Aug2024, Vol. 25 Issue 8, p1124-1135, 12p

Proteomic profiling improves prognostic risk stratification of the Sarculator nomogram in soft tissue sarcomas of the extremities and trunk wall.

Authors: Chadha, Madhumeeta, Iadecola, Sara, Jenks, Andrew, Pankova, Valeriya, Tam, Yuen Bun, Burns, Jessica, Arthur, Amani, Wilding, Christopher P., Chen, Liang, Chudasama, Priya, Callegaro, Dario, Strauss, Dirk C., Thway, Khin, Gronchi, Alessandro, Jones, Robin L., Miceli, Rosalba, Pasquali, Sandro, Huang, Paul H.

Source: Cancer Medicine; Jul2024, Vol. 13 Issue 14, p1-12, 12p

Subject Terms: CELL cycle proteins, SARCOMA, DNA replication, OVERALL survival, DRUG target

SWATH mass spectrometry as a tool for quantitative profiling of the matrisome

Authors: Krasny, Lukas, Bland, Philip, Kogata, Naoko, Wai, Patty, Howard, Beatrice A., Natrajan, Rachael C., Huang, Paul H.

Source: In Journal of Proteomics 30 October 2018 189:11-22