Indigofera suffruticosa aerial parts extract induce G2/M arrest and ATR/CHK1 pathway in Jurkat cells

Authors: Hong-Loan Tran, Kuei-Hung Lai, Hsun-Shuo Chang, Yi-Siao Chen, Hui-Chun Wang, Shuen-Shin Yang, Hsueh-Wei Chang, Chin-Mu Hsu, Chia-Hung Yen, Hui-Hua Hsiao

Source: BMC Complementary Medicine and Therapies, Vol 24, Iss 1, Pp 1-13 (2024)

Subject Terms: Folk medicine, Indigofera suffruticosa, Acute lymphoblastic leukemia, Other systems of medicine, RZ201-999

File Description: electronic resource

Relation: https://doaj.org/toc/2662-7671

Access URL: https://doaj.org/article/01af68687ea5422db2ea0daea71d0e42

The SAR analysis of dietary polyphenols and their antagonistic effects on bortezomib at physiological concentrations

Authors: Tran Tran Thi Van, Hsun-Shuo Chang, Ho-Cheng Wu, Chung-Kuang Lu, Hui-Chi Huang, Michal Korinek, Hui-Hua Hsiao, Chia-Hung Yen

Source: Frontiers in Pharmacology, Vol 15 (2024)

Subject Terms: multiple myeloma, boronic acid-based proteasome inhibitor, bortezomib, polyphenol, vicinal diol moieties, physiological concentrations, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphar.2024.1403424/full; https://doaj.org/toc/1663-9812

Access URL: https://doaj.org/article/9fb452b1035d4f45b211c79b9d20ab50

In vitro and in silico studies of 7′′,8′′-buddlenol D anti-inflammatory lignans from Carallia brachiata as p38 MAP kinase inhibitors

Authors: Nonthaneth Nalinratana, Utid Suriya, Chanyanuch Laprasert, Nakuntwalai Wisidsri, Preeyaporn Poldorn, Thanyada Rungrotmongkol, Wacharee Limpanasitthikul, Ho-Cheng Wu, Hsun-Shuo Chang, Chaisak Chansriniyom

Source: Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/ba735781d3224e15a6f06eab04bd0595

Correction: Nukulkit et al. Eight Indole Alkaloids from the Roots of Maerua siamensis and Their Nitric Oxide Inhibitory Effects. Molecules 2022, 27, 7558

Authors: Sasiwimon Nukulkit, Angkana Jantimaporn, Preeyaporn Poldorn, Mattaka Khongkow, Thanyada Rungrotmongkol, Hsun-Shuo Chang, Rutt Suttisri, Chaisak Chansriniyom

Source: Molecules, Vol 29, Iss 7, p 1526 (2024)

Subject Terms: n/a, Organic chemistry, QD241-441

File Description: electronic resource

Relation: https://www.mdpi.com/1420-3049/29/7/1526; https://doaj.org/toc/1420-3049

Access URL: https://doaj.org/article/89736c0c675344fc8d374b14bb33ad06

Chemical Constituents with Anti-Lipid Droplet Accumulation and Anti-Inflammatory Activity from Elaeagnus glabra

Authors: Ju-Hsin Cheng, Ho-Cheng Wu, Chia-Hung Yen, Tsong-Long Hwang, Horng-Huey Ko, Hsun-Shuo Chang

Source: Plants, Vol 12, Iss 16, p 2943 (2023)

Subject Terms: Elaeagnus glabra, Elaeagnaceae, triterpenoid, flavonoid, anti-lipid droplet activity, anti-inflammation, Botany, QK1-989

File Description: electronic resource

Relation: https://www.mdpi.com/2223-7747/12/16/2943; https://doaj.org/toc/2223-7747

Access URL: https://doaj.org/article/8573473a394146ea9e7b0c47bed8b650

Eight Indole Alkaloids from the Roots of Maerua siamensis and Their Nitric Oxide Inhibitory Effects

Authors: Sasiwimon Nukulkit, Angkana Jantimaporn, Preeyaporn Poldorn, Mattaka Khongkow, Thanyada Rungrotmongkol, Hsun-Shuo Chang, Rutt Suttisri, Chaisak Chansriniyom

Source: Molecules, Vol 27, Iss 21, p 7558 (2022)

Subject Terms: Maerua siamensis, Capparaceae, indole alkaloids, nitric oxide inhibition, Organic chemistry, QD241-441

File Description: electronic resource

Relation: https://www.mdpi.com/1420-3049/27/21/7558; https://doaj.org/toc/1420-3049

Access URL: https://doaj.org/article/5dc7d0ed3bfc4ae09f52bb1c27ef50da

Prinsepiae Nux Extract Activates NRF2 Activity and Protects UVB-Induced Damage in Keratinocyte

Authors: Shih-Han Wang, Yi-Siao Chen, Kuei-Hung Lai, Chung-Kuang Lu, Hsun-Shuo Chang, Ho-Cheng Wu, Feng-Lin Yen, Lo-Yun Chen, Jin-Ching Lee, Chia-Hung Yen

Source: Antioxidants, Vol 11, Iss 9, p 1755 (2022)

Subject Terms: NRF2, natural product, Shen Nong Ben Cao Jing, ROS, UVB irradiation, antioxidant, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.mdpi.com/2076-3921/11/9/1755; https://doaj.org/toc/2076-3921

Access URL: https://doaj.org/article/21bfce6cbbaf43688cd0b7049c572d0b

Correction: Cheng et al. Novel Antifungal Dimers from the Roots of Taiwania cryptomerioides. Molecules 2022, 27, 437

Authors: Ming-Jen Cheng, Ming-Der Wu, Chao-Lin Chang, Hsun-Shuo Chang, Chiou-Fung Chyu, Yueh-Hsiung Kuo

Source: Molecules, Vol 27, Iss 18, p 6056 (2022)

Subject Terms: n/a, Organic chemistry, QD241-441

File Description: electronic resource

Relation: https://www.mdpi.com/1420-3049/27/18/6056; https://doaj.org/toc/1420-3049

Access URL: https://doaj.org/article/3ecacaddd5564efc8c5cfe9caf3a9310

Cryptocaryone Promotes ROS-Dependent Antiproliferation and Apoptosis in Ovarian Cancer Cells

Authors: Yu-Chieh Chen, Che-Wei Yang, Te-Fu Chan, Ammad Ahmad Farooqi, Hsun-Shuo Chang, Chia-Hung Yen, Ming-Yii Huang, Hsueh-Wei Chang

Source: Cells, Vol 11, Iss 4, p 641 (2022)

Subject Terms: Cryptocaryone, ovarian cancer, apoptosis, DNA damage, Cytology, QH573-671

File Description: electronic resource

Relation: https://www.mdpi.com/2073-4409/11/4/641; https://doaj.org/toc/2073-4409

Access URL: https://doaj.org/article/71ee40d1bd5e409bac35ae940a351ac8

Meso-Dihydroguaiaretic Acid Ameliorates Acute Respiratory Distress Syndrome through Inhibiting Neutrophilic Inflammation and Scavenging Free Radical

Authors: Yen-Tung Lee, Yu-Li Chen, Yi-Hsuan Wu, Ih-Sheng Chen, Hsun-Shuo Chang, Yi-Hsuan Wang, Shih-Hsin Chang, Yi-Hsiu Wu, Ting-I Kao, Huang-Ping Yu, Tsong-Long Hwang

Source: Antioxidants, Vol 11, Iss 1, p 123 (2022)

Subject Terms: acute respiratory distress syndrome, meso-dihydroguaiaretic acid, neutrophil, reactive oxygen species, superoxide anion, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.mdpi.com/2076-3921/11/1/123; https://doaj.org/toc/2076-3921

Access URL: https://doaj.org/article/2bc9ddd3394a4098a99dc4875eb3371b

Novel Antifungal Dimers from the Roots of Taiwania cryptomerioides

Authors: Ming-Jen Cheng, Ming-Der Wu, Chao-Lin Chang, Hsun-Shuo Chang, Chiou-Fung Chyu, Yueh-Hsiung Kuo

Source: Molecules, Vol 27, Iss 2, p 437 (2022)

Subject Terms: Taiwania cryptomerioides, Taxodiaceae, novel skeleton, dimer, diterpenoid, antifungal activities, Organic chemistry, QD241-441

File Description: electronic resource

Relation: https://www.mdpi.com/1420-3049/27/2/437; https://doaj.org/toc/1420-3049

Access URL: https://doaj.org/article/98273302d6a0460492c10ac8475535d3

Investigations into Chemical Components from Monascus purpureus with Photoprotective and Anti-Melanogenic Activities

Authors: Ho-Cheng Wu, Yih-Fung Chen, Ming-Jen Cheng, Ming-Der Wu, Yen-Lin Chen, Hsun-Shuo Chang

Source: Journal of Fungi, Vol 7, Iss 8, p 619 (2021)

Subject Terms: Monascus purpureus, xanthonoids, naphthalenone, azaphilone, photoprotection, anti-melanogenesis, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.mdpi.com/2309-608X/7/8/619; https://doaj.org/toc/2309-608X

Access URL: https://doaj.org/article/122b7807edd7453d9a4f58b62990cc81

Identification of Beilschmiedia tsangii Root Extract as a Liver Cancer Cell–Normal Keratinocyte Dual-Selective NRF2 Regulator

Authors: Yi-Siao Chen, Hsun-Shuo Chang, Hui-Hua Hsiao, Yih-Fung Chen, Yi-Ping Kuo, Feng-Lin Yen, Chia-Hung Yen

Source: Antioxidants, Vol 10, Iss 4, p 544 (2021)

Subject Terms: NRF2, high-throughput screen, adjuvant treatment, natural product, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.mdpi.com/2076-3921/10/4/544; https://doaj.org/toc/2076-3921

Access URL: https://doaj.org/article/404088eea3a7459cae2f9ad5a440390c

Chemical Constituent of β-Glucuronidase Inhibitors from the Root of Neolitsea acuminatissima

Authors: Chu-Hung Lin, Hsiao-Jung Chou, Chih-Chi Chang, Ih-Sheng Chen, Hsun-Shuo Chang, Tian-Lu Cheng, Yueh-Hsiung Kuo, Horng-Huey Ko

Source: Molecules, Vol 25, Iss 21, p 5170 (2020)

Subject Terms: Neolitsea acuminatissima, Lauraceae, root, carboline, eudesmanolide, β-Glucuronidase, Organic chemistry, QD241-441

File Description: electronic resource

Relation: https://www.mdpi.com/1420-3049/25/21/5170; https://doaj.org/toc/1420-3049

Access URL: https://doaj.org/article/cee96fb62642403189e228203e6a4bd9

Phytochemical Investigation and Anti-Inflammatory Activity of the Leaves of Machilus japonica var. kusanoi

Authors: Shiou-Ling Li, Ho-Cheng Wu, Tsong-Long Hwang, Chu-Hung Lin, Shuen-Shin Yang, Hsun-Shuo Chang

Source: Molecules, Vol 25, Iss 18, p 4149 (2020)

Subject Terms: Machilus japonica var. kusanoi, lauraceae, butanolide, lignan, anti-inflammatory activity, Organic chemistry, QD241-441

File Description: electronic resource

Relation: https://www.mdpi.com/1420-3049/25/18/4149; https://doaj.org/toc/1420-3049

Access URL: https://doaj.org/article/047f286546de4808a0291ae4dc58a8e3

Anti-Inflammatory and Antibacterial Activity Constituents from the Stem of Cinnamomum validinerve

Authors: Chi-Lung Yang, Ho-Cheng Wu, Tsong-Long Hwang, Chu-Hung Lin, Yin-Hua Cheng, Chia-Chi Wang, Hung-Lin Kan, Yueh-Hsiung Kuo, Ih-Sheng Chen, Hsun-Shuo Chang, Ying-Chi Lin

Source: Molecules, Vol 25, Iss 15, p 3382 (2020)

Subject Terms: Cinnamomum validinerve, Lauraceae, anti-inflammatory activity, anti-acne activity, Organic chemistry, QD241-441

File Description: electronic resource

Relation: https://www.mdpi.com/1420-3049/25/15/3382; https://doaj.org/toc/1420-3049

Access URL: https://doaj.org/article/3053e191beff4979934c1bec586a15fa

Chemical Constituents with GNMT-Promoter-Enhancing and NRF2-Reduction Activities from Taiwan Agarwood Excoecaria formosana

Authors: Ho-Cheng Wu, Ming-Jen Cheng, Chia-Hung Yen, Yi-Ming Arthur Chen, Yi-Siao Chen, Ih-Sheng Chen, Hsun-Shuo Chang

Source: Molecules, Vol 25, Iss 7, p 1746 (2020)

Subject Terms: Excoecaria formosana, Euphorbiaceae, secondary metabolites, GNMT promoter activity, NRF2 activity, Organic chemistry, QD241-441

File Description: electronic resource

Relation: https://www.mdpi.com/1420-3049/25/7/1746; https://doaj.org/toc/1420-3049

Access URL: https://doaj.org/article/ca0bba213d1e421e813ff8ca323b468c

New and Cytotoxic Components from Antrodia camphorata

Authors: Tzong-Huei Lee, Chien-Chih Chen, Jih-Jung Chen, Hui-Fen Liao, Hsun-Shuo Chang, Ping-Jyun Sung, Mei-Hwei Tseng, Sheng-Yang Wang, Horng-Huey Ko, Yueh-Hsiung Kuo

Source: Molecules, Vol 19, Iss 12, Pp 21378-21385 (2014)

Subject Terms: Antrodia camphorata, phenylmethanoid, dihydrostilbene, abeo-ergostane, cytotoxicity, Organic chemistry, QD241-441

File Description: electronic resource

Relation: http://www.mdpi.com/1420-3049/19/12/21378; https://doaj.org/toc/1420-3049

Access URL: https://doaj.org/article/d2972bc4515c4426aefd5e71c586cdf9

Attenuation of antigen-specific T helper 1 immunity by Neolitsea hiiranensis and its derived terpenoids

Authors: Yin-Hua Cheng, Ih-Sheng Chen, Ying-Chi Lin, Chun-Wei Tung, Hsun-Shuo Chang, Chia-Chi Wang

Source: PeerJ, Vol 4, p e2758 (2016)

Subject Terms: T-bet, Neolitsea, IFN-γ, Th1 cells, Terpenoids, β-caryophyllene oxide, Medicine, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://peerj.com/articles/2758.pdf; https://peerj.com/articles/2758/; https://doaj.org/toc/2167-8359

Access URL: https://doaj.org/article/23a6310b2943429eb191c6f1f101eca6

Reevesioside A, a cardenolide glycoside, induces anticancer activity against human hormone-refractory prostate cancers through suppression of c-myc expression and induction of G1 arrest of the cell cycle.

Authors: Wohn-Jenn Leu, Hsun-Shuo Chang, She-Hung Chan, Jui-Ling Hsu, Chia-Chun Yu, Lih-Ching Hsu, Ih-Sheng Chen, Jih-Hwa Guh

Source: PLoS ONE, Vol 9, Iss 1, p e87323 (2014)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3903642?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/48bc6de0cab044a5b752cb618d06a070