HC-Pro inhibits HEN1 methyltransferase activity, leading to autophagic degradation of AGO1

Authors: Zhao-Jun Pan, Wei-Lun Wei, Phuong-Anh Tran, Ru-Ying Fang, Thanh Ha Pham, John L. Bowman, Chao-Tzu Chung, Bing-Nan Shen, Ju-Ting Yang, Han-Han Chang, Wann-Neng Jane, Chiung-Hsiang Cheng, Chia-Chi Wang, Hsin-Yi Wu, Syuan-Fei Hong, Qian-Wen Shang, Sin-Fen Hu, Pin-Chun Lin, Fu-Hui Wu, Choun-Sea Lin, Yu-Ling Hung, Tang-Long Shen, Shih-Shun Lin

Source: Nature Communications, Vol 16, Iss 1, Pp 1-18 (2025)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/2f8f45724ee44aa79748984edacf624b

The branched N-glycan of PD-L1 predicts immunotherapy responses in patients with recurrent/metastatic HNSCC

Authors: Huai-Cheng Huang, Yen-Lin Huang, Yi-Ju Chen, Hsin-Yi Wu, Chia-Lang Hsu, Hsiang-Fong Kao, Bin-Chi Liao, Min-Shu Hsieh, Neng-Yu Lin, Yu-Hao Liao, Hsin-Lin Chen, Chun-Nan Chen, Tseng-Cheng Chen, Cheng-Ping Wang, Tsung-Lin Yang, Min-Chuan Huang, Mei-Chun Lin, Pei-Jen Lou

Source: Oncogenesis, Vol 13, Iss 1, Pp 1-10 (2024)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2157-9024

Access URL: https://doaj.org/article/70de69921c8547aeb318aa0db5ded965

Bifidobacterium alleviate metabolic disorders via converting methionine to 5’-methylthioadenosine

Authors: Qiang Lyu, Rou-An Chen, Hsiao-Li Chuang, Hsin-Bai Zou, Lihong Liu, Li-Kang Sung, Po-Yu Liu, Hsin-Yi Wu, Hsin-Yuan Chang, Wan-Ju Cheng, Wei-Kai Wu, Ming-Shiang Wu, Cheng-Chih Hsu

Source: Gut Microbes, Vol 16, Iss 1 (2024)

Subject Terms: Bifidobacterium, 5’-methylthioadenosine, LC-MS/MS metabolomics, probiotic, prebiotic, postbiotic, Diseases of the digestive system. Gastroenterology, RC799-869

File Description: electronic resource

Relation: https://doaj.org/toc/1949-0976; https://doaj.org/toc/1949-0984

Access URL: https://doaj.org/article/86dca9a746a54a6888601f6719d34083

Targeting tumor O‐glycosylation modulates cancer–immune‐cell crosstalk and enhances anti‐PD‐1 immunotherapy in head and neck cancer

Authors: Mei‐Chun Lin, Ya‐Ting Chuang, Hsin‐Yi Wu, Chia‐Lang Hsu, Neng‐Yu Lin, Min‐Chuan Huang, Pei‐Jen Lou

Source: Molecular Oncology, Vol 18, Iss 2, Pp 350-368 (2024)

Subject Terms: core 1 β1,3‐galactosyltransferase, head and neck cancer, IL‐6, immune checkpoint inhibitor, itraconazole, O‐glycosylation, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1574-7891; https://doaj.org/toc/1878-0261

Access URL: https://doaj.org/article/e9ed1e8e7af94aa582632080fc33d22f

Decreased B4GALT1 promotes hepatocellular carcinoma cell invasiveness by regulating the laminin-integrin pathway

Authors: Po-Da Chen, Ying-Yu Liao, Yu-Chia Cheng, Hsin-Yi Wu, Yao-Ming Wu, Min-Chuan Huang

Source: Oncogenesis, Vol 12, Iss 1, Pp 1-12 (2023)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2157-9024

Access URL: https://doaj.org/article/790cc5db8f7c4a8d8f89b564db89a0b6

Hypermethylation of ACADVL is involved in the high-intensity interval training-associated reduction of cardiac fibrosis in heart failure patients

Authors: Chih-Chin Hsu, Jong-Shyan Wang, Yu-Chiau Shyu, Tieh-Cheng Fu, Yu-Hsiang Juan, Shin-Sheng Yuan, Chao-Hung Wang, Chi-Hsiao Yeh, Po-Cheng Liao, Hsin-Yi Wu, Pang-Hung Hsu

Source: Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-15 (2023)

Subject Terms: Heart failure, Aerobic exercise, Cardiac fibrosis, Epigenetics, DNA methylation, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/1479-5876

Access URL: https://doaj.org/article/adfb930b7b8b40228b6e03e41d3f3a1c

Tumors Established in a Defective Immune Environment Reprogram the Oncogenic Signaling Pathways to Escalate Tumor Antigenicity

Authors: Chiao-Hsu Ke, Hsin-Yi Wu, Yu-Shan Wang, Wei-Hsiang Huang, Chen-Si Lin

Source: Biomedicines, Vol 12, Iss 4, p 846 (2024)

Subject Terms: tumor suppressors, immunogenicity, tumor antigens, proliferative cell signaling, PTEN, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.mdpi.com/2227-9059/12/4/846; https://doaj.org/toc/2227-9059

Access URL: https://doaj.org/article/23e5744c810448a4b0f3c3ce40b038b9

LCMD: Lung Cancer Metabolome Database

Authors: Wei-Sheng Wu, Hsin-Yi Wu, Pin-Hsuan Wang, Ting-Yu Chen, Kuan-Ru Chen, Chih-Wei Chang, Dong-En Lee, Bo-Heng Lin, William Chih-Wei Chang, Pao-Chi Liao

Source: Computational and Structural Biotechnology Journal, Vol 20, Iss , Pp 65-78 (2022)

Subject Terms: Lung cancer, Biomarker, Database, Mass spectrometry, Metabolite, Metabolome, Biotechnology, TP248.13-248.65

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2001037021005109; https://doaj.org/toc/2001-0370

Access URL: https://doaj.org/article/ce35a270708b43a68e022ebc6cdb7c7b

Investigation of the effects of P1 on HC-pro-mediated gene silencing suppression through genetics and omics approaches

Authors: Sin-Fen Hu, Wei-Lun Wei, Syuan-Fei Hong, Ru-Ying Fang, Hsin-Yi Wu, Pin-Chun Lin, Neda Sanobar, Hsin-Ping Wang, Margo Sulistio, Chun-Ta Wu, Hsiao-Feng Lo, Shih-Shun Lin

Source: Botanical Studies, Vol 61, Iss 1, Pp 1-18 (2020)

Subject Terms: P1/HC-Pro, Viral suppressor, Posttranscriptional gene silencing, MicroRNA, Omics, Comparative network, Botany, QK1-989

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s40529-020-00299-x; https://doaj.org/toc/1999-3110

Access URL: https://doaj.org/article/d1a20412ddfc49b582fbc7222a6086c1

Quantitative Proteome Analysis Reveals Melissa officinalis Extract Targets Mitochondrial Respiration in Colon Cancer Cells

Authors: Tzu-Ting Kuo, Li-Chun Lin, Hsin-Yi Chang, Pei-Jung Chiang, Hsin-Yi Wu, Tai-Yuan Chen, Shih-Min Hsia, Tsui-Chin Huang

Source: Molecules, Vol 27, Iss 14, p 4533 (2022)

Subject Terms: Melissa officinalis, colorectal cancer, proteomics analysis, reactive oxygen species, mitochondrial respiratory chain complex, Organic chemistry, QD241-441

File Description: electronic resource

Relation: https://www.mdpi.com/1420-3049/27/14/4533; https://doaj.org/toc/1420-3049

Access URL: https://doaj.org/article/eb75205d478d4ec7a958f17af26fe3e1

Quantitative of progesterone using isotope dilution-matrix-assisted laser desorption ionization-time of flight mass spectrometry

Authors: Ming-Hui Yang, Han-Ping You, Hsin-Yi Wu, Yi-Ming Arthur Chen, Ying-Fong Huang, Yu-Chang Tyan

Source: MethodsX, Vol 7, Iss , Pp 100812- (2020)

Subject Terms: MALDI-TOF/MS, Progesterone, Isotope dilution, Science

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2215016120300327; https://doaj.org/toc/2215-0161

Access URL: https://doaj.org/article/7077fd48e1f34e028054b93432f34fed

Temporal regulation of Lsp1 O-GlcNAcylation and phosphorylation during apoptosis of activated B cells

Authors: Jung-Lin Wu, Hsin-Yi Wu, Dong-Yan Tsai, Ming-Feng Chiang, Yi-Ju Chen, Shijay Gao, Chun-Cheng Lin, Chun-Hung Lin, Kay-Hooi Khoo, Yu-Ju Chen, Kuo-I. Lin

Source: Nature Communications, Vol 7, Iss 1, Pp 1-11 (2016)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/f4ea53b30f1641559ce4aa1a196ad329

Phosphorylation of CPAP by Aurora-A Maintains Spindle Pole Integrity during Mitosis

Authors: En-Ju Chou, Liang-Yi Hung, Chieh-Ju C. Tang, Wen-Bin Hsu, Hsin-Yi Wu, Pao-Chi Liao, Tang K. Tang

Source: Cell Reports, Vol 14, Iss 12, Pp 2975-2987 (2016)

Subject Terms: Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211124716302200; https://doaj.org/toc/2211-1247

Access URL: https://doaj.org/article/1bb22a2249ab43efa6ec85328495d44f

Twin live births following transfer using eight-cell cleavage stage embryos on Day 4 with developmental arrest

Authors: Hsin-Yi Wu, Yi-Chi Lin, Kuo-Chung Lan

Source: Taiwanese Journal of Obstetrics & Gynecology, Vol 50, Iss 3, Pp 381-384 (2011)

Subject Terms: Gynecology and obstetrics, RG1-991

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1028455911000192; https://doaj.org/toc/1028-4559

Access URL: https://doaj.org/article/da43cadd7cb341f788172bd8abd832eb

GSHSite: exploiting an iteratively statistical method to identify s-glutathionylation sites with substrate specificity.

Authors: Yi-Ju Chen, Cheng-Tsung Lu, Kai-Yao Huang, Hsin-Yi Wu, Yu-Ju Chen, Tzong-Yi Lee

Source: PLoS ONE, Vol 10, Iss 4, p e0118752 (2015)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC4388702?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/86e3bdbee52e4478be7b58ec1b063fa7

Cytomegalovirus infection and fetal death in one monozygotic twin

Authors: Hsin-Yi Wu, Shun-Chen Huang, Hsin-Chun Huang, Te-Yao Hsu, Kuo-Chung Lan

Source: Taiwanese Journal of Obstetrics & Gynecology, Vol 50, Iss 2, Pp 230-232 (2011)

Subject Terms: Gynecology and obstetrics, RG1-991

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S102845591100009X; https://doaj.org/toc/1028-4559

Access URL: https://doaj.org/article/350b37096fb647d596ca8c34a351a6b3

Untargeted metabolomics analysis assisted by signal selection for comprehensively identifying metabolites of new psychoactive substances: 4-MeO-α-PVP as an example.

Authors: Hsin-Yi Wu¹ hsinyiwu@ntu.edu.tw, Yuan-Chih Chen², Jing-Fang Hsu³, Hsiang-Ting Lu², Yu-Yi Pan⁴, Mi-Chia Ma⁴, Pao-Chi Liao² liaopc@mail.ncku.edu.tw

Source: Journal of Food & Drug Analysis. 2023, Vol. 31 Issue 1, p137-151. 16p.

Subject Terms: *COMPUTER software, *STATISTICS, *COMPUTER simulation, *PSYCHIATRIC drugs, *METABOLOMICS, *LIQUID chromatography, *ANIMAL experimentation, *WORKFLOW, *MASS spectrometry, *DESCRIPTIVE statistics, *RESEARCH funding, *COLLECTION & preservation of biological specimens, *DATA analysis, *MOLECULAR structure, *METABOLITES

A precise delay generator circuit using the average delay technique

Authors: Hsin-Yi Wu, Chung-Chun Chen, Chun-Pang Wu, Hen-Wai Tsao

Source: 2008 IEEE International Symposium on VLSI Design, Automation and Test (VLSI-DAT) VLSI Design, Automation and Test, 2008. VLSI-DAT 2008. IEEE International Symposium on. :236-239 Apr, 2008

Relation: 2008 IEEE International Symposium on VLSI Design, Automation and Test (VLSI-DAT)

PHOMAG: a photolithography machine allocation game

Authors: Shi-Chung Chang, Chung-Yang Liu, Ming-Der Hu, Hsin-Yi Wu, Hsin-Chen Wu, Cheng-Lin Chao, Ren-Cheng Chen

Source: 1997 IEEE International Symposium on Semiconductor Manufacturing Conference Proceedings (Cat. No.97CH36023) Semiconductor manufacturing Semiconductor Manufacturing Conference Proceedings, 1997 IEEE International Symposium on. :P11-P13 1997

Relation: 1997 IEEE International Symposium on Semiconductor Manufacturing Conference Proceedings

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