In Vitro and In Silico Mechanistic Insights into miR-21-5p-Mediated Topoisomerase Drug Resistance in Human Colorectal Cancer Cells

Authors: Jung-Chien Chen, Yao-Yu Hsieh, Hsiang-Ling Lo, Albert Li, Chia-Jung Chou, Pei-Ming Yang

Source: Biomolecules, Vol 9, Iss 9, p 467 (2019)

Subject Terms: autophagy, colorectal cancer, Connectivity Map, drug resistance, microRNA, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.mdpi.com/2218-273X/9/9/467; https://doaj.org/toc/2218-273X

Access URL: https://doaj.org/article/0cab808c0007495684a48947e4cc5947

A gene expression signature-based approach reveals the mechanisms of action of the Chinese herbal medicine berberine.

Authors: Kuen-Haur Lee¹, Hsiang-Ling Lo¹, Wan-Chun Tang¹, Heidi Hao-yun Hsiao¹, Pei-Ming Yang¹ yangpm@tmu.edu.tw

Source: Scientific Reports. 9/19/2014, p1-9. 9p.

Subject Terms: *BERBERINE, *HERBAL medicine, *CHINESE medicine, *GENE expression, *HISTONE deacetylase, *RAPAMYCIN

S-Adenosyl-L-methionine-competitive inhibitors of the histone methyltransferase EZH2 induce autophagy and enhance drug sensitivity in cancer cells.

Authors: Tsang-Pai Liu, Hsiang-Ling Lo, Li-Shan Wei, Heidi Hao-yun Hsiao, Pei-Ming Yang

Source: Anti-Cancer Drugs; Feb2015, Vol. 26 Issue 2, p139-147, 9p