POLE-Mutated Uterine Carcinosarcomas: A Clinicopathologic and Molecular Study of 11 Cases

Authors: Hammer, Phoebe M. ^a, Momeni-Boroujeni, Amir ^b, Kolin, David L. ^c, Kingsley, Leandra ^a, Folkins, Ann ^a, Geisick, Rachel L.P. ^a, Ho, Chandler ^a, Suarez, Carlos J. ^a, Howitt, Brooke E. ^{a, ∗}

Source: In Modern Pathology March 2025 38(3)

Deep learning uncovers histological patterns of YAP1/TEAD activity related to disease aggressiveness in cancer patients

Authors: Schmauch, Benoit ^{1, 20, ∗}, Cabeli, Vincent ¹, Domingues, Omar Darwiche ¹, Le Douget, Jean-Eudes ¹, Hardy, Alexandra ^{1, ∗∗}, Belbahri, Reda ¹, Maussion, Charles ¹, Romagnoni, Alberto ¹, Eckstein, Markus ², Fuchs, Florian ^{3, 4, 5}, Swalduz, Aurélie ⁶, Lantuejoul, Sylvie ⁷, Crochet, Hugo ⁸, Ghiringhelli, François ⁹, Derangere, Valentin ^{9, 10, 11, 12}, Truntzer, Caroline ^{9, 10, 11, 12}, Pass, Harvey ¹³, Moreira, Andre L. ¹⁴, Chiriboga, Luis ¹⁴, Zheng, Yuanning ¹⁵, Ozawa, Michael ¹⁵, Howitt, Brooke E. ¹⁶, Gevaert, Olivier ¹⁶, Girard, Nicolas ¹⁷, Rexhepaj, Elton ¹⁸, Valtingojer, Iris ¹⁸, Debussche, Laurent ¹⁸, de Rinaldis, Emanuele ¹⁹, Nestle, Frank ¹⁹, Spanakis, Emmanuel ¹⁸, Fantin, Valeria R. ¹⁹, Durand, Eric Y. ¹, Classe, Marion ¹⁸, Von Loga, Katharina ¹, Pronier, Elodie ¹, Cesaroni, Matteo ¹⁸

Source: In iScience 17 January 2025 28(1)

Fertility-sparing treatment for atypical polypoid adenomyoma

Authors: Beshar, Isabel ^{a, ⁎}, Lang, Susan ^b, Dorigo, Oliver ^c, Howitt, Brooke E ^d, Liu, Caroline ^e, Karam, Amer ^c

Source: In Gynecologic Oncology Reports April 2025 58

Diabetes mellitus complications associated with recurrence of stage I endometrioid endometrial cancer: A single-center retrospective study

Authors: Nief, Corrine A., Long, Sara E., McCleary, Tamra-Lee, Kidd, Elizabeth, Litkouhi, Babak, Howitt, Brooke E.

Source: In Gynecologic Oncology November 2024 190:298-306

Scattering-Based Light-Sheet Microscopy Imaging of Human Papillomavirus–Associated Squamous Lesions of the Anal Canal: A Proof-of-Principle Study

Authors: Liang, Brooke, Zhao, Jingwei, Kim, Yongjun, Barry-Holson, Keegan Q., Bingham, David B., Charville, Gregory W., Darragh, Teresa M., Folkins, Ann K., Howitt, Brooke E., Kong, Christina S., Longacre, Teri A., McHenry, Austin J., Toland, Angus M.S., Zhang, Xiaoming, Lim, Koeun, Khan, Michelle J., Kang, Dongkyun, Yang, Eric J.

Source: In Modern Pathology June 2024 37(6)

UCHL1 is a potential molecular indicator and therapeutic target for neuroendocrine carcinomas

Authors: Liu, Shiqin, Chai, Timothy, Garcia-Marques, Fernando, Yin, Qingqing, Hsu, En-Chi, Shen, Michelle, Shaw Toland, Angus Martin, Bermudez, Abel, Hartono, Alifiani B., Massey, Christopher F., Lee, Chung S., Zheng, Liwei, Baron, Maya, Denning, Caden J., Aslan, Merve, Nguyen, Holly M., Nolley, Rosalie, Zoubeidi, Amina, Das, Millie, Kunder, Christian A., Howitt, Brooke E., Soh, H. Tom, Weissman, Irving L., Liss, Michael A., Chin, Arnold I., Brooks, James D., Corey, Eva, Pitteri, Sharon J., Huang, Jiaoti, Stoyanova, Tanya

Source: In Cell Reports Medicine 20 February 2024 5(2)

FIGO 2023 endometrial cancer staging: too much, too soon?

Authors: McCluggage, W Glenn ^{1, *}, Bosse, Tjalling ², Gilks, C Blake ³, Howitt, Brooke E ⁴, McAlpine, Jessica N ⁵, Nucci, Marisa R ⁶, Rabban, Joseph T ⁷, Singh, Naveena ⁸, Talia, Karen L ⁹, Parra-Herran, Carlos ¹⁰

Source: In International Journal of Gynecological Cancer January 2024 34(1):138-143

Adjuvant radiation therapy in early-stage endometrial cancer with abnormal beta-catenin expression is associated with improved local control

Authors: Hui, Caressa, Mendoza, Maria G., Snyder, John, Dorigo, Oliver, Litkouhi, Babak, Renz, Malte, Karam, Amer, Devereaux, Kelly, Howitt, Brooke E., Kidd, Elizabeth A.

Source: Gynecologic oncology. 174:42-48

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100194216995.0x000001&indx=1&recIds=ETOCvdc_100194216995.0x000001

Consensus based recommendations for the diagnosis of serous tubal intraepithelial carcinoma: an international Delphi study

Authors: Bogaerts, Joep M A, Bommel, Majke H D, Hermens, Rosella P M G, Steenbeek, Miranda P, Hullu, Joanne A, Laak, Jeroen A W M, Shih, Ie‐Ming, McCluggage, W Glenn, Gilks, C Blake, Carlson, Joseph W, Rabban, Joseph T, Ewing‐Graham, Patricia C, Killeen, Jeffrey L, Lastra, Ricardo, Parkash, Vinita, O'Riain, Ciaran, Staebler, Annette, Vang, Russell, Bulten, Johan, Vijver, Koen K, Sherman, Mark E, Desouki, Mohamed Mokhtar, Turashvili, Gulisa, Bart, Joost, Bosse, Tjalling, Kooreman, Loes F S, Singh, Naveena, Stewart, Colin J R, Lax, Sigurd F, Howitt, Brooke E, Xing, Deyin, Attygalle, Ayoma D, Vroobel, Katherine M, Schwartz, Lauren E, Jonges, Trudy G N, Nucci, Marisa, Schoolmeeste, Kenneth J, Devouassoux‐Shisheboran, Mojgan, Soong, Thing R, Simons, Michiel

Source: Histopathology. 83(1):67-79

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100191010786.0x000001&indx=1&recIds=ETOCvdc_100191010786.0x000001

Molecular correlates of invasion pattern in HPV‐associated endocervical adenocarcinoma: emergence of two distinct risk‐stratified tiers

Authors: Sharma, Aarti E, Hodgson, Anjelica J, Howitt, Brooke E, Olkhov‐Mitsel, Ekaterina, Djordevic, Bojana, Park, Kay J, Nucci, Marisa R, Parra‐Herran, Carlos

Source: Histopathology. 82(7):1067-1078

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100182817927.0x000001&indx=1&recIds=ETOCvdc_100182817927.0x000001

Aberrant nuclear β-catenin distribution does not prognosticate recurrences of endometrioid endometrial cancers – A retrospective single-institutional study

Authors: Beshar, Isabel, Moon, Ashley S., Darji, Himani, Liu, Caroline, Jennings, Michael T., Dorigo, Oliver, Litkouhi, Babak, Diver, Elisabeth J., Karam, Amer K., Howitt, Brooke E., Renz, Malte

Source: In Gynecologic Oncology December 2023 179:85-90

Detection of FOXL2 C134W Mutation Status by a Novel BaseScope In Situ Hybridization Assay is Highly Sensitive and Specific for Adult Granulosa Cell Tumors

Authors: Hammer, Phoebe M., Wang, Aihui, Beard, Crystal, Zdravkovic, Sabrina, Tenney, Troy, Liang, Brooke, Das, Ishani, Bremer, Ryan, Wang, Li-Chong, McCluggage, W. Glenn, Stewart, Colin J.R., Howitt, Brooke E.

Source: In Modern Pathology November 2023 36(11)

Does lymph node assessment change the prognostic significance of substantial LVSI and p53 status in endometrial endometrioid carcinoma?

Authors: Hui, Caressa, Mendoza, Maria G., von Eyben, Rie, Dorigo, Oliver, Litkouhi, Babak, Renz, Malte, Karam, Amer, Hammer, Phoebe M., Howitt, Brooke E., Kidd, Elizabeth

Source: In Gynecologic Oncology October 2023 177:150-156

PTEN Deficiency in Tubo-Ovarian High-Grade Serous Carcinoma is Associated with Poor Progression-Free Survival and is Mutually Exclusive with CCNE1 Amplification

Authors: Zhang, Xiaoming, Wang, Aihui, Han, Lucy, Liang, Brooke, Allard, Grace, Diver, Elisabeth, Howitt, Brooke E.

Source: In Modern Pathology May 2023 36(5)

High-Grade Endometrial Stromal Sarcomas With YWHAE::NUTM2 Gene Fusion Exhibit Recurrent CDKN2A Alterations and Absence of p16 Staining is a Poor Prognostic Marker

Authors: Kommoss, Felix K.F., Mar, Lisa-Marie, Howitt, Brooke E., Hanley, Krisztina, Turashvilli, Gulisa, Buslei, Rolf, Irving, Julie A., Dickson, Brendan C., Koelsche, Christian, Sinn, Hans-Peter, Schirmacher, Peter, von Deimling, Andreas, Chiang, Sarah, McCluggage, W. Glenn, Croce, Sabrina, Stewart, Colin J.R., Lee, Cheng-Han

Source: In Modern Pathology March 2023 36(3)

HPV-independent, p53-wild-type vulvar intraepithelial neoplasia: a review of nomenclature and the journey to characterize verruciform and acanthotic precursor lesions of the vulva

Authors: Parra-Herran, Carlos, Nucci, Marisa R., Singh, Naveena, Rakislova, Natalia, Howitt, Brooke E., Hoang, Lynn, Gilks, C. Blake, Bosse, Tjalling, Watkins, Jaclyn C.

Source: In Modern Pathology October 2022 35(10):1317-1326

Well‐differentiated lipomatous neoplasms with p53 alterations: a clinicopathological and molecular study of eight cases with features of atypical pleomorphic lipomatous tumour

Authors: Hammer, Phoebe M, Kunder, Christian A, Howitt, Brooke E, Charville, Gregory W

Source: Histopathology. 80(4):656-664

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100141608145.0x000001&indx=1&recIds=ETOCvdc_100141608145.0x000001

GRM1 Immunohistochemistry Distinguishes Chondromyxoid Fibroma From its Histologic Mimics

Authors: Toland, Angus M.S., Lam, Suk Wai, Varma, Sushama, Wang, Aihui, Howitt, Brooke E., Kunder, Christian A., Kerr, Darcy A., Szuhai, Karoly, Bovée, Judith V.M.G., Charville, Gregory W.

Source: American journal of surgical pathology. 46(10):1407-1414

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100179294608.0x000001&indx=1&recIds=ETOCvdc_100179294608.0x000001

Data Set for the Reporting of Carcinomas of the Vagina: Recommendations From the International Collaboration on Cancer Reporting (ICCR)

Authors: Wong, Richard Wing-Cheuk, Webster, Fleur, Bosse, Tjalling, Focchi, Gustavo, Gilks, C. Blake, Hoang, Lynn, Howitt, Brooke E., McAlpine, Jessica, Ordi, Jaume, Singh, Naveena, Lax, Sigurd F., McCluggage, W. Glenn

Source: International journal of gynecological pathology. 41(6):S23-S33

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100178624702.0x000001&indx=1&recIds=ETOCvdc_100178624702.0x000001

Data Set for Reporting of Uterine Malignant and Potentially Malignant Mesenchymal Tumors: Recommendations From the International Collaboration on Cancer Reporting (ICCR)

Authors: Nucci, Marisa R., Webster, Fleur, Croce, Sabrina, George, Suzanne, Howitt, Brooke E., Ip, Philip P.C., Lee, Cheng-Han, Rabban, Joseph T., Soslow, Robert A., van der Griend, Rachael, Lax, Sigurd F., McCluggage, W. Glenn

Source: International journal of gynecological pathology. 41(6):S44-S63

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100178624724.0x000001&indx=1&recIds=ETOCvdc_100178624724.0x000001