Chronic Intestinal Inflammation Suppresses Brain Activity by Inducing Neuroinflammation in Mice

Authors: Mitchell, Jonathon, Kim, Su Jin, Howe, Cody, Lee, Seulah, Her, Ji Yun, Patel, Marisa, Kim, Gayoung, Lee, Jaewon, Im, Eunok, Rhee, Sang Hoon

Source: American journal of pathology. 192(1):72-86

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663 PHOSPHATASE AND TENSIN HOMOLG (PTEN) REGULATES AUTOPHAGY AND UBIQUITINATION PATHWAYS TO CONTROL THE CELLULAR LEVEL OF SNAIL/SLUG TRANSCRIPTION REPRESSOR PROTEINS, THEREBY MAINTAINING THE INTESTINAL EPITHELIAL CELL JUNCTION

Authors: Kim, Su Jin, Howe, Cody S., Kim, Gayoung, Jeong, Sihyun, Im, Eunok, Rhee, Sang H.

Source: Gastroenterology. 164(6):S-128-S-128

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100194429601.0x000001&indx=1&recIds=ETOCvdc_100194429601.0x000001

Differential expression of tumor-associated genes and altered gut microbiome with decreased Akkermansia muciniphila confer a tumor-preventive microenvironment in intestinal epithelial Pten-deficient mice

Authors: Howe, Cody, Kim, Su Jin, Mitchell, Jonathon, Im, Eunok, Kim, Yong Sung, Kim, You Sun, Rhee, Sang Hoon

Source: In BBA - Molecular Basis of Disease December 2018 1864(12):3746-3758

Pten gene deletion in intestinal epithelial cells enhances susceptibility to Salmonella Typhimurium infection in mice

Authors: Howe, Cody, Mitchell, Jonathon, Kim, Su Jin, Im, Eunok, Rhee, Sang Hoon

Source: Journal of microbiology. 57(11):1012-1018

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Loss of Autotaxin inhibits Toll‐like receptor4‐mediated immune mechanisms and promote spontaneous colitis in Il10‐ko mice

Authors: Rhee, Sang H., Kim, Su Jin, Howe, Cody, Jeong, Sihyun, Im, Eunok

Source: FASEB journal. 36

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Tu1514: AUTOTAXIN DEFICIENCY SUPPRESSES TOLL-LIKE RECEPTOR 4-MEDIATED IMMUNE MECHANISM TO PROMOTE COLITIS DEVELOPMENT

Authors: Kim, Su Jin, Howe, Cody S., Park, Soyeong, Im, Eunok, Rhee, Sang H.

Source: Gastroenterology. 162(7):S-994-S-994

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100167648508.0x000001&indx=1&recIds=ETOCvdc_100167648508.0x000001

9: CHRONIC COLITIS IN MICE CAN CAUSE HMGB1-MEDIATED INFLAMMATORY RESPONSES IN THE BRAIN

Authors: Mitchell, Jonathon, Kim, Su Jin, Howe, Cody S., Kim, Gayoung, Heo, Gwangbeom, Jeong, Sihyun, Im, Eunok, Rhee, Sang H.

Source: Gastroenterology. 162(7):S-3-S-3

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100167618002.0x000001&indx=1&recIds=ETOCvdc_100167618002.0x000001

Autotaxin loss accelerates intestinal inflammation by suppressing TLR4‐mediated immune responses

Authors: Kim, Su Jin, Howe, Cody, Mitchell, Jonathon, Choo, Jieun, Powers, Alexandra, Oikonomopoulos, Angelos, Pothoulakis, Charalabos, Hommes, Daniel W, Im, Eunok, Rhee, Sang Hoon

Source: EMBO reports. 21(10)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100128296771.0x000001&indx=1&recIds=ETOCvdc_100128296771.0x000001

Sa1113 – Gut Dysbiosis with Decreased Akkermansia Muciniphila.And Altered Tumor-Gene Expression Contribute to a Tumorpreventive Microenvironment in Intestinal Epithelial Ptendeficient Mice

Authors: Rhee, Sang H., Howe, Cody S., Kim, Su Jin, Mitchell, Jonathon, Im, Eunok

Source: Gastroenterology. 156(6):S-274-S-274

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100080959636.0x000001&indx=1&recIds=ETOCvdc_100080959636.0x000001

Su1458 MK2 INHIBITION PROTECTS AGAINST INFLAMMATION AND FIBROSIS IN MURINE CHRONIC PANCREATITIS

Authors: Howe, Cody, Syrcle, Ryan, Conwell, Darwin L., Beswick, Ellen J.

Source: In Gastroenterology 18-21 May 2024 166(5) Supplement:S

CHRONIC COLITIS ALTERS BRAIN ACTIVITY BY INDUCING HMGB1-MEDIATED PYROPTOSIS IN MICE

Authors: Mitchell, Jonathon, Kim, Su Jin, Howe, Cody, Patel, Marisa, Kim, Gayoung, Heo, Gwangbeom, Im, Eunok, Rhee, Sang

Source: Gastroenterology. 162(3):S56-S56

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100157129758.0x000001&indx=1&recIds=ETOCvdc_100157129758.0x000001

P158 LOSS OF AUTOTAXIN ALTERS INNATE AND ADAPTIVE IMMUNE MECHANISM AND PROMOTES SPONTANEOUS COLITIS IN IL10-KO MICE

Authors: Kim, Su Jin, Howe, Cody, Mitchell, Jonathon, Im, Eunok, Rhee, Sang

Source: Gastroenterology. 158(3):S52-S53

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100097837284.0x000001&indx=1&recIds=ETOCvdc_100097837284.0x000001

Relatable Stories

Authors: Howe, Cody

Source: Brain & life. 16(5):8-8

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100112487887.0x000001&indx=1&recIds=ETOCvdc_100112487887.0x000001

Blockage of protease-activated receptor 2 exacerbates inflammation in high-fat environment partly through autophagy inhibition.

Authors: Ji Yun Her, Yunna Lee, Su Jin Kim, Gwangbeom Heo, Jieun Choo, Yuju Kim, Howe, Cody, Sang Hoon Rhee, Hak Sun Yu, Hae Young Chung, Pothoulakis, Charalabos, Im, Eunok

Source: American Journal of Physiology: Gastrointestinal & Liver Physiology; Jan2021, Vol. 320 Issue 1, pG30-G42, 13p

Subject Terms: PROTEASE-activated receptors, POLY ADP ribose, INFLAMMATORY bowel diseases, AUTOPHAGY, WEIGHT loss, HIGH-fat diet

Corticotropin-Releasing Hormone Receptor Alters the Tumor Development and Growth in Apcmin/+ Mice and in a Chemically-Induced Model of Colon Cancer.

Authors: Lee, Yunna, Ma, Elise L., Patel, Marisa, Kim, Gayoung, Howe, Cody, Pothoulakis, Charalabos, Kim, Yong Sung, Im, Eunok, Rhee, Sang Hoon, Rizzo, Manfredi

Source: International Journal of Molecular Sciences; Feb2021, Vol. 22 Issue 3, p1043-1043, 1p

Subject Terms: COLON cancer, CYCLOOXYGENASE 2, TUMOR growth, PHOSPHOLIPASE A2, PSYCHOLOGICAL stress