Metatranscriptomic profiling reveals pathogen and host response signatures of pediatric acute sinusitis and upper respiratory infection

Authors: Andrew C. Doxey, Nooran Abu Mazen, Max Homm, Vivian Chu, Manjot Hunjan, Briallen Lobb, Sojin Lee, Marcia Kurs-Lasky, John V. Williams, William MacDonald, Monika Johnson, Jeremy A. Hirota, Nader Shaikh

Source: Genome Medicine, Vol 17, Iss 1, Pp 1-22 (2025)

Subject Terms: Acute sinusitis, Host response, Upper respiratory infections, Pediatrics, Metatranscriptomics, RNA-seq, Medicine, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1756-994X

Access URL: https://doaj.org/article/dbda58e75ab845e8b0a9a4d177ee6a28

Implementation of a rapid host-protein diagnostic test for distinguishing bacterial and viral infections in adults presenting to urgent care centers: a pragmatic cohort study

Authors: Boaz Kalmovich, Daniella Rahamim-Cohen, Ilan Yehoshua, Sara Kivity, Noam Orvieto, Shirley Shapiro Ben David

Source: BMC Medicine, Vol 23, Iss 1, Pp 1-11 (2025)

Subject Terms: Rapid host response test, Urgent care centers, Antibiotics, Viral, Bacterial, Diagnostics, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/1741-7015

Access URL: https://doaj.org/article/44258648fe0c4eb8b05182b1cfabb7b2

RNA-containing extracellular vesicles in infection

Authors: Kayo Schemiko Almeida, Suélen Andreia Rossi, Lysangela Ronalte Alves

Source: RNA Biology, Vol 21, Iss 1, Pp 1275-1289 (2024)

Subject Terms: Extracellular vesicles, RNA, infection, host-response, bacteria, fungi, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1547-6286; https://doaj.org/toc/1555-8584

Access URL: https://doaj.org/article/4e83cf37fd044d78acfa25375dece1f6

Industrial diet intervention modulates the interplay between gut microbiota and host in semi-stray dogs

Authors: Soufien Rhimi, Amin Jablaoui, Juan Hernandez, Vincent Mariaule, Nizar Akermi, Tristan Méric, Héla Mkaouar, Magdalena Wysocka, Adam Lesner, Mohamed Ali Borgi, Emmanuelle Maguin, Moez Rhimi

Source: Animal Microbiome, Vol 6, Iss 1, Pp 1-16 (2024)

Subject Terms: Dog, Diet intervention, Semi-stray dog, Industrial diet, Gut microbiota, Host response, Veterinary medicine, SF600-1100, Microbiology, QR1-502

File Description: electronic resource

Relation: https://doaj.org/toc/2524-4671

Access URL: https://doaj.org/article/be72ecc6ae78400796c3465e48a94295

Host Response in Critically Ill Patients Aged 65 Years or Older: A Prospective Study

Authors: Lian H, Wang G, Zhang H, Wang X, Zhang S

Source: Clinical Interventions in Aging, Vol Volume 19, Pp 1789-1805 (2024)

Subject Terms: host response, critically ill, old patients, immune response, inflammatory response, procoagulant response, Geriatrics, RC952-954.6

File Description: electronic resource

Relation: https://www.dovepress.com/host-response-in-critically-ill-patients-aged-65-years-or-older-a-pros-peer-reviewed-fulltext-article-CIA; https://doaj.org/toc/1178-1998

Access URL: https://doaj.org/article/c0ee0e4236db4712827d184b3ab0f146

Determining the Prognostic Value of Complete Blood Count Subgroup Parameters in Staphylococcus aureus Bacteremia

Authors: Emily L. Matthews, Thomas J. Dilworth

Source: Journal of Patient-Centered Research and Reviews, Vol 11, Iss 3, Pp 197-203 (2024)

Subject Terms: s. aureus bacteremia, host response, complete blood count, cbc subgroup parameters, clinical outcomes, Medicine

File Description: electronic resource

Relation: https://institutionalrepository.aah.org/cgi/viewcontent.cgi?article=2073&context=jpcrr; https://doaj.org/toc/2330-0698

Access URL: https://doaj.org/article/f187379e0fc2462d959cb50ee9915794

Diagnostic Efficiency of the Blood-Based Cepheid 3-Gene Host Response Test and Urine-Based Lipoarabinomannan for Active Tuberculosis Case Detection at a General Hospital in China

Authors: Ji Z, Bi S, Lu B, Zheng L, Jin X, Huang S, Jiang L, Wang Y, Ding C, Xu K

Source: Infection and Drug Resistance, Vol Volume 17, Pp 4467-4475 (2024)

Subject Terms: active tuberculosis, diagnostic, three-gene host response, lipoarabinomannan, auroc., Infectious and parasitic diseases, RC109-216

File Description: electronic resource

Relation: https://www.dovepress.com/diagnostic-efficiency-of-the-blood-based-cepheid-3-gene-host-response--peer-reviewed-fulltext-article-IDR; https://doaj.org/toc/1178-6973

Access URL: https://doaj.org/article/eb39b84f81c44a3d9260e78961ca493b

Timing matters in macrophage/CD4+ T cell interactions: an agent-based model comparing Mycobacterium tuberculosis host-pathogen interactions between latently infected and naïve individuals

Authors: Alexis Hoerter, Alexa Petrucciani, Jordan Bonifacio, Eusondia Arnett, Larry S. Schlesinger, Elsje Pienaar

Source: mSystems, Vol 10, Iss 3 (2025)

Subject Terms: tuberculosis, agent based model, trained immunity, granuloma formation, host-cell interactions, host response, Microbiology, QR1-502

File Description: electronic resource

Relation: https://doaj.org/toc/2379-5077

Access URL: https://doaj.org/article/48c05d7d0e1846dd9d98ed8fc534d9be

Capsular polysaccharide enables Klebsiella pneumoniae to evade phagocytosis by blocking host-bacteria interactions

Authors: Xiaoxuan Liu, Qi Xu, Xuemei Yang, Heng Heng, Chen Yang, Guan Yang, Mingxiu Peng, Edward Wai-Chi Chan, Sheng Chen

Source: mBio, Vol 16, Iss 3 (2025)

Subject Terms: Klebsiella pneumoniae, virulence mechanisms, capsular polysaccharide, host recognition, host response, Microbiology, QR1-502

File Description: electronic resource

Relation: https://doaj.org/toc/2150-7511

Access URL: https://doaj.org/article/b884ffd8431b4ad28b55ba565a0c9430

Proteomic profiling of the local and systemic immune response to pediatric respiratory viral infections

Authors: Emily Lydon, Christina M. Osborne, Brandie D. Wagner, Lilliam Ambroggio, J. Kirk Harris, Ron Reeder, Todd C. Carpenter, Aline B. Maddux, Matthew K. Leroue, Nadir Yehya, Joseph L. DeRisi, Mark W. Hall, Athena F. Zuppa, Joseph Carcillo, Kathleen Meert, Anil Sapru, Murray M. Pollack, Patrick McQuillen, Daniel A. Notterman, Charles R. Langelier, Peter M. Mourani

Source: mSystems, Vol 10, Iss 1 (2025)

Subject Terms: proteomics, LRTI, pneumonia, host response, co-infection, viral pneumonia, Microbiology, QR1-502

File Description: electronic resource

Relation: https://doaj.org/toc/2379-5077

Access URL: https://doaj.org/article/cee365fb36c94a1f847b84c25db1232b

Transcriptomic Response of Arabidopsis thaliana to Pseudomonas syringae Infection: An In Silico Approach

Authors: Amir Ghaffar Shahriari, Mohamad Hamed Ghodoum Parizipour, Yaser Biniaz, Aminallah Tahmasebi, Fatemeh Gholizadeh

Source: Journal of Genetic Resources, Vol 10, Iss 2, Pp 209-220 (2024)

Subject Terms: arabidopsis, gene expression, host response, transcriptomics, pseudomonas, Genetics, QH426-470

File Description: electronic resource

Relation: https://sc.journals.umz.ac.ir/article_5278_1bdd032e2b16ec1ea6ed1b85f0eec2c5.pdf; https://doaj.org/toc/2423-4257; https://doaj.org/toc/2588-2589

Access URL: https://doaj.org/article/63a0c8328b944419ba4fcf68d749f354

Integrating omics techniques and culture-independent systems may improve the detection of persistent candidemia: data from an observational study

Authors: Anna Maria Peri, Kevin O’Callaghan, Nastaran Rafiei, Haakon Bergh, Alexis Tabah, Mark D Chatfield, Patrick NA Harris, David L Paterson

Source: Annals of Clinical Microbiology and Antimicrobials, Vol 23, Iss 1, Pp 1-6 (2024)

Subject Terms: Candidemia, Blood culture, Rapid diagnostic tests, T2 magnetic resonance, Host-response, Omics, Therapeutics. Pharmacology, RM1-950, Infectious and parasitic diseases, RC109-216, Microbiology, QR1-502

File Description: electronic resource

Relation: https://doaj.org/toc/1476-0711

Access URL: https://doaj.org/article/13fba46668cf444381ff7bd5d5365613

Cytological and ultrastructural investigation of pathogen infection pathway and host responses in asparagus stem infected by Phomopsis asparagi

Authors: Liping Sun, Yange Li, Xiaoting Li, Xinyi Ruan, Yueyan Zhao, Ruidong Wen, Shuaijie Wei, Ning Chen, Yulan Zhang, Shufen Li, Wujun Gao

Source: Phytopathology Research, Vol 6, Iss 1, Pp 1-13 (2024)

Subject Terms: Asparagus stem blight, Host response, Infectious process, Phomopsis asparagi, Plant culture, SB1-1110

File Description: electronic resource

Relation: https://doaj.org/toc/2524-4167

Access URL: https://doaj.org/article/de5879a4045a47448ec46af3fea907fd

Biomarkers in pulmonary infections: a clinical approach

Authors: Pedro Póvoa, Luís Coelho, José Pedro Cidade, Adrian Ceccato, Andrew Conway Morris, Jorge Salluh, Vandack Nobre, Saad Nseir, Ignacio Martin-Loeches, Thiago Lisboa, Paula Ramirez, Anahita Rouzé, Daniel A. Sweeney, Andre C. Kalil

Source: Annals of Intensive Care, Vol 14, Iss 1, Pp 1-15 (2024)

Subject Terms: Pulmonary infections, Pathogen-specific biomarkers, Host-response biomarkers, C-reactive protein, Procalcitonin, Medical emergencies. Critical care. Intensive care. First aid, RC86-88.9

File Description: electronic resource

Relation: https://doaj.org/toc/2110-5820

Access URL: https://doaj.org/article/68dad71ce7d6469ca7be4b5410caf1b3

Transcriptome analysis of resistant and susceptible Medicago truncatula genotypes in response to spring black stem and leaf spot disease

Authors: Jacob R. Botkin, Shaun J. Curtin

Source: BMC Plant Biology, Vol 24, Iss 1, Pp 1-17 (2024)

Subject Terms: RNA-seq, Host response, Medicago truncatula, Necrotrophic fungus, Ascochyta medicaginicola, Botany, QK1-989

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2229

Access URL: https://doaj.org/article/175b67072d374afb939a00967152c325

Syngeneic adipose-derived stromal cells modulate the immune response but have limited persistence within decellularized adipose tissue implants in C57BL/6 mice

Authors: Walker, John T. ^a, Cooper, Tyler T. ^b, Dunmore-Buyze, Joy ^c, Serack, Fiona E. ^e, Brooks, Courtney ^f, Grant, Aaron ^g, Drangova, Maria ^{c, d}, Lajoie, Gilles ^b, Dekaban, Gregory A. ^{c, h}, Flynn, Lauren E. ^{a, e, i, ⁎}

Source: In Acta Biomaterialia 15 March 2025 195:169-182

Endotoxin, not DNA, determines the host response and tissue regeneration behavior of acellular biologic scaffolds

Authors: Cheng, Wenyue ^{a, 1}, Huang, Yonggang ^{b, 1}, Dai, Jing ^{a, 1}, Zhao, Meibiao ^c, Wang, Yulu ^a, Turner, Neill ^{d, ⁎}, Zhang, Jian ^{a, ⁎}

Source: In Acta Biomaterialia 15 March 2025 195:157-168

Host-Directed Adjunctive Therapies in Immunocompromised Patients with Pneumonia

Authors: Hensley, Matthew K. ^∗, Dela Cruz, Charles S. ¹

Source: In Clinics in Chest Medicine March 2025 46(1):37-48

Soluble CD72 concurrently impairs T cell functions while enhances inflammatory response in sepsis

Authors: Yang, Jing ^{a, 1}, Ma, Chengyong ^{b, 1}, Feng, Zhongxue ^{a, 1}, Xiao, Fei ^c, Kang, Yan ^{b, ⁎}, Zhang, Wei ^{a, ⁎}, Liao, Xuelian ^{b, ⁎}

Source: In International Immunopharmacology 6 February 2025 147

Editorial: How RSV outsmarts the host

Authors: Stephania A. Cormier, Lawrence M. Kauvar, Ralph A. Tripp

Source: Frontiers in Immunology, Vol 15 (2024)

Subject Terms: RSV, host response, immune response, treatment, vaccine, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2024.1529014/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/3d7403c049114f16831eeab80fb9bd55