Enhancing preventive and therapeutic cancer vaccine efficacy through biotherapeutic ligand-associated extracellular vesicles

Authors: Kahraman, Tamer, Akpinar, Gozde Gucluler, Yildirim, Muzaffer, Larssen, Pia, Bayyurt-Kocabas, Banu, Yagci, Fuat C., Gursel, Arda, Horuluoglu, Begum Han, Yazar, Volkan, Ayanoglu, Ihsan Cihan, Yildirim, Tugce Canavar, Evcili, Irem, Yilmaz, Ismail C., Eldh, Maria, Gabrielsson, Susanne, Guler, Ulku, Salih, Bekir, Gursel, Mayda, Gursel, Ihsan

Source: In Journal of Controlled Release December 2024 376:618-631

Autoantibodies against a subunit of mitochondrial respiratory chain complex I in inclusion body myositis

Authors: Notarnicola, Antonella ^{a, b, c, ⁎}, Hellstrom, Ceke ^d, Horuluoglu, Begum ^{a, c}, Pin, Elisa ^d, Preger, Charlotta ^a, Bonomi, Francesco ^e, De Paepe, Boel ^f, De Bleecker, Jan L. ^f, Van der Kooi, Anneke J. ^g, De Visser, Marianne ^g, Sacconi, Sabrina ^h, Machado, Pedro ⁱ, Badrising, Umesh A. ^j, Rietveld, Anke ^k, Pruijn, Ger ^l, Rothwell, Simon ^m, Lilleker, James B. ^{n, o}, Chinoy, Hector ^{n, o}, Benveniste, Olivier ^p, Svenungsson, Elisabet ^{a, b}, Idborg, Helena ^{a, c}, Jakobsson, Per-Johan ^{a, b, c}, Nilsson, Peter ^d, Lundberg, Ingrid E. ^{a, b, c}

Source: In Journal of Autoimmunity December 2024 149

Identification of proteinase 3 autoreactive CD4+T cells and their T-cell receptor repertoires in antineutrophil cytoplasmic antibody–associated vasculitis

Authors: Sharma, Ravi Kumar, Yoosuf, Niyaz, Afonso, Marcelo, Scheffschick, Andrea, Avik, Aune, Bartoletti, Alice, Horuluoglu, Begum, Diaz Boada, Juan Sebastian, Boddul, Sanjay Kumar, Jonasdottir, Asta Dögg, Lövström, Björn, Brauner, Hanna, Raposo, Bruno, Chemin, Karine, Bruchfeld, Annette, Gunnarsson, Iva, Malmström, Vivianne

Source: Kidney international. 103(5):973-985

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100187701327.0x000001&indx=1&recIds=ETOCvdc_100187701327.0x000001

The human bone marrow plasma cell compartment in rheumatoid arthritis - Clonal relationships and anti-citrulline autoantibody producing cells

Authors: Hensvold, Aase, Horuluoglu, Begum, Sahlström, Peter, Thyagarajan, Radha, Diaz Boada, Juan Sebastian, Hansson, Monika, Mathsson-Alm, Linda, Gerstner, Christina, Sippl, Natalie, Israelsson, Lena, Wedin, Rikard, Steen, Johanna, Klareskog, Lars, Réthi, Bence, Catrina, Anca I., Diaz-Gallo, Lina-Marcela, Malmström, Vivianne, Grönwall, Caroline

Source: In Journal of Autoimmunity April 2023 136

Autoantibodies against four-and-a-half-LIM domain 1 (FHL1) in inflammatory myopathies: results from an Australian single-centre cohort

Authors: Galindo-Feria, Angeles S, Horuluoglu, Begum, Day, Jessica, Fernandes-Cerqueira, Catia, Wigren, Edvard, Gräslund, Susanne, Proudman, Susanna, Lundberg, Ingrid E, Limaye, Vidya

Source: Rheumatology. 61(10):4145-4154

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100163923071.0x000001&indx=1&recIds=ETOCvdc_100163923071.0x000001

Anti‐Jo1 autoantibodies, from clinic to the bench

Authors: Galindo‐Feria, Angeles S., Horuluoglu, Begum, Lundberg, Ingrid E.

Source: Rheumatology & Autoimmunity. 2(2):57-68

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100155012123.0x000001&indx=1&recIds=ETOCvdc_100155012123.0x000001

CpG Oligonucleotides as Vaccine Adjuvants

Authors: Kayraklioglu, Neslihan, Horuluoglu, Begum, Klinman, Dennis M.

Source: Methods in molecular biology. 2197:51-86

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN624739874&indx=1&recIds=ETOCRN624739874

Single‐cell profiling of muscle‐infiltrating T cells in idiopathic inflammatory myopathies

Authors: Argyriou, Alexandra, Horuluoglu, Begum, Galindo‐Feria, Angeles Shunashy, Diaz‐Boada, Juan Sebastian, Sijbranda, Merel, Notarnicola, Antonella, Dani, Lara, Vollenhoven, Annika, Ramsköld, Daniel, Nennesmo, Inger, Dastmalchi, Maryam, Lundberg, Ingrid E, Diaz‐Gallo, Lina‐Marcela, Chemin, Karine

Source: EMBO molecular medicine. 15(10)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100195604211.0x000001&indx=1&recIds=ETOCvdc_100195604211.0x000001

PAM3 supports the generation of M2-like macrophages from lupus patient monocytes and improves disease outcome in murine lupus

Authors: Horuluoglu, Begum, Bayik, Defne, Kayraklioglu, Neslihan, Goguet, Emilie, Kaplan, Mariana J., Klinman, Dennis M.

Source: In Journal of Autoimmunity May 2019 99:24-32

Autoantibodies against the melanoma differentiation–associated protein 5 in patients with dermatomyositis target the helicase domains.

Authors: Gompel, Eveline Van, Demirdal, Deniz, Fernandes-Cerqueira, Catia, Horuluoglu, Begum, Galindo-Feria, Angeles, Wigren, Edvard, Gräslund, Susanne, Langhe, Ellen De, Benveniste, Olivier, Notarnicola, Antonella, Chemin, Karine, Lundberg, Ingrid E

Source: Rheumatology; May2024, Vol. 63 Issue 5, p1466-1473, 8p

Subject Terms: DERMATOMYOSITIS, MELANOMA, RESEARCH funding, AUTOANTIBODIES, ENZYME-linked immunosorbent assay, DESCRIPTIVE statistics, INTERFERONS, WESTERN immunoblotting

PAM3 protects against DSS-induced colitis by altering the M2:M1 ratio.

Authors: Horuluoglu, Begum H.¹, Kayraklioglu, Neslihan¹, Tross, Debra¹, Klinman, Dennis¹ klinmand@gmail.com

Source: Scientific Reports. 4/8/2020, Vol. 10 Issue 1, p1-8. 8p.

Subject Terms: *INFLAMMATION, *GASTROINTESTINAL system, *INFLAMMATORY bowel diseases, *IMMUNOSUPPRESSIVE agents, *MACROPHAGES

Aminoacyl-tRNA Synthetases: On Anti-Synthetase Syndrome and Beyond.

Authors: Galindo-Feria, Angeles S., Notarnicola, Antonella, Lundberg, Ingrid E., Horuluoglu, Begum

Source: Frontiers in Immunology; 5/13/2022, Vol. 13, p1-16, 16p

Subject Terms: AMINOACYL-tRNA synthetases, GENETIC translation, AUTOIMMUNE diseases, RAYNAUD'S disease, INTERSTITIAL lung diseases, NEUROLOGICAL disorders

CD19-Targeting CAR T-Cell Therapy for Antisynthetase Syndrome.

Authors: Lundberg, Ingrid E., Galindo-Feria, Angeles S., Horuluoglu, Begum

Source: JAMA: Journal of the American Medical Association; 6/27/2023, Vol. 329 Issue 24, p2130-2131, 2p

Subject Terms: T cells, DERMATOMYOSITIS, MYOSITIS, IMMUNOGLOBULIN producing cells

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Critical Role of B Cells in Toll-Like Receptor 7-Mediated Protection against Listeria monocytogenesInfection

Authors: Kayraklioglu, Neslihan, Horuluoglu, Begum, Elango, Madhivanan, Klinman, Dennis M.

Source: Infection and Immunity; September 2019, Vol. 87 Issue: 12

Liposomal D-and K-type CpG ODN combination confers synergistic immune activation and act as an efficient tumor vaccine.

Authors: Horuluoglu, Begum Han¹, Gursel, Ihsan¹

Source: Turkish Journal of Immunology. 2016 Supplement, Vol. 4, p60-60. 1/2p.

Subject Terms: *LIPOSOMES, *CPG nucleotides, *CANCER vaccines, *IMMUNOTHERAPY, *OVALBUMINS, *THERAPEUTICS

Enhanced delivery and internalization of iron oxide nanoparticle-loaded exosomes.

Authors: Yildirim, Muzaffer, Gucluler, Gozde, Horuluoglu, Begum Han, Kahraman, Tamer, Gursel, Ihsan

Source: Turkish Journal of Immunology; 2016 Supplement, Vol. 4, p61-61, 1/2p

Subject Terms: EXOSOMES, IRON oxides, NANOPARTICLES, DRUG delivery systems, MAGNETIC fields