A combination of two human neutralizing antibodies prevents SARS-CoV-2 infection in cynomolgus macaques

Authors: Cobb, Ronald R., Nkolola, Joseph, Gilchuk, Pavlo, Chandrashekar, Abishek, Yu, Jingyou, House, Robert V., Earnhart, Christopher G., Dorsey, Nicole M., Hopkins, Svetlana A., Snow, Doris M., Chen, Rita E., VanBlargan, Laura A., Hechenblaickner, Manuel, Hoppe, Brian, Collins, Laura, Tomic, Milan T., Nonet, Genevieve H., Hackett, Kyal, Slaughter, James C., Lewis, Mark G., Andersen, Hanne, Cook, Anthony, Diamond, Michael S., Carnahan, Robert H., Barouch, Dan H., Crowe, James E., Jr.

Source: In Med 11 March 2022 3(3):188-203

Computationally restoring the potency of a clinical antibody against Omicron

Authors: Desautels, Thomas A., Arrildt, Kathryn T., Zemla, Adam T., Lau, Edmond Y., Zhu, Fangqiang, Ricci, Dante, Cronin, Stephanie, Zost, Seth J., Binshtein, Elad, Scheaffer, Suzanne M., Dadonaite, Bernadeta, Petersen, Brenden K., Engdahl, Taylor B., Chen, Elaine, Handal, Laura S., Hall, Lynn, Goforth, John W., Vashchenko, Denis, Nguyen, Sam, Weilhammer, Dina R., Lo, Jacky Kai-Yin, Rubinfeld, Bonnee, Saada, Edwin A., Weisenberger, Tracy, Lee, Tek-Hyung, Whitener, Bradley, Case, James B., Ladd, Alexander, Silva, Mary S., Haluska, Rebecca M., Grzesiak, Emilia A., Earnhart, Christopher G., Hopkins, Svetlana, Bates, Thomas W., Thackray, Larissa B., Segelke, Brent W., Lillo, Antonietta Maria, Sundaram, Shivshankar, Bloom, Jesse D., Diamond, Michael S., Crowe, James E., Carnahan, Robert H., Faissol, Daniel M.

Source: Nature; May 2024, Vol. 629 Issue: 8013 p878-885, 8p

Multipathogen and monopathogen protection against the bacterial and viral infections associated with biological warfare, cardiac diseases, and cancers

Treatments for viral infections using IFN cytokines and ribavirin, alone or in combination

Evaluation of strategies to modify Anti-SARS-CoV-2 monoclonal antibodies for optimal functionality as therapeutics.

Authors: House, Robert V., Broge, Thomas A., Suscovich, Todd J., Snow, Doris M., Tomic, Milan T., Nonet, Genevieve, Bajwa, Kamaljit, Zhu, Guangyu, Martinez, Zachary, Hackett, Kyal, Earnhart, Christopher G., Dorsey, Nicole M., Hopkins, Svetlana A., Natour, Dalia S., Davis, Heather D., Anderson, Michael S., Gainey, Melicia R., Cobb, Ronald R.

Source: PLoS ONE; 6/3/2022, Vol. 17 Issue 6, p1-24, 24p

Subject Terms: COVID-19, SARS-CoV-2, MONOCLONAL antibodies, ANTIBODY-dependent cell cytotoxicity, COVID-19 pandemic, HUMORAL immunity, IMMUNE response, THERAPEUTICS

Effective antiprotease-antibiotic treatment of experimental anthrax

Authors: MacAfee Rebecca, Weinstein Raymond S, Hopkins Svetlana, Popova Taissia G, Popov Serguei G, Fryxell Karl J, Chandhoke Vikas, Bailey Charles, Alibek Ken

Source: BMC Infectious Diseases, Vol 5, Iss 1, p 25 (2005)

Subject Terms: Infectious and parasitic diseases, RC109-216

File Description: electronic resource

Relation: http://www.biomedcentral.com/1471-2334/5/25; https://doaj.org/toc/1471-2334

Access URL: https://doaj.org/article/0a03d9b0fe174289834cf5286e5c4e33

Effective antiprotease-antibiotic treatment of experimental anthrax.

Authors: Popov, Serguei G., Popova, Taissia G., Hopkins, Svetlana, Weinstein, Raymond S., MacAfee, Rebecca, Fryxell, Karl J., Chandhoke, Vikas, Bailey, Charles, Alibek, Ken

Source: BMC Infectious Diseases; 2005, Vol. 5 Issue 1, p25-14, 14p, 1 Chart, 6 Graphs

Subject Terms: ANTHRAX, ANTIBIOTICS, BACILLUS anthracis, BIOINFORMATICS, PROTEINS, MOLECULAR pathology