Light-controlled inhibition of BRAFV600E kinase

Authors: Hoorens, Mark W.H., Ourailidou, Maria E., Rodat, Theo, van der Wouden, Petra E., Kobauri, Piermichele, Kriegs, Malte, Peifer, Christian, Feringa, Ben L., Dekker, Frank J., Szymanski, Wiktor

Source: In European Journal of Medicinal Chemistry 1 October 2019 179:133-146

In vitro and in vivo analyses of eFAP: a novel FAP-targeting small molecule for radionuclide theranostics and other oncological interventions.

Authors: van der Heide, Circe D., Ma, Hanyue, Hoorens, Mark W.H., Campeiro, Joana D., Stuurman, Debra C., de Ridder, Corrina M.A., Seimbille, Yann, Dalm, Simone U.

Source: EJNMMI Radiopharmacy & Chemistry; 7/29/2024, Vol. 9 Issue 1, p1-17, 17p

Subject Terms: RADIONUCLIDE imaging, SMALL molecules, CONFOCAL microscopy, PHARMACOPHORE, COMPANION diagnostics

Reversible, Spatial and Temporal Control over Protein Activity Using Light

Authors: Hoorens, Mark W.H., Szymanski, Wiktor

Source: In Trends in Biochemical Sciences August 2018 43(8):567-575

Structure-kinetic relationship studies of cannabinoid CB2 receptor agonists reveal substituent-specific lipophilic effects on residence time

Authors: Soethoudt, Marjolein, Hoorens, Mark W.H., Doelman, Ward, Martella, Andrea, van der Stelt, Mario, Heitman, Laura H.

Source: In Biochemical Pharmacology June 2018 152:129-142