Mannose inhibits PKM2 lactylation to induce pyroptosis in bladder cancer and activate antitumor immune responses

Authors: Haoyi Jin, Pingeng Wu, Chengcheng Lv, Shouyi Zhang, Yunchao Zhang, Changqi Li, Ruxu Gao, Guangyi Shan, Huan Bi, Hong Chang, Xi Liu, Yu Zeng

Source: Communications Biology, Vol 8, Iss 1, Pp 1-13 (2025)

Subject Terms: Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/2399-3642

Access URL: https://doaj.org/article/f6865dbd50234b3ea320aebe1a94b474

Machine learning-based prediction of postoperative pancreatic fistula after laparoscopic pancreaticoduodenectomy

Authors: Qianchang Wang, Zhe Wang, Fangfeng Liu, Zhengjian Wang, Qingqiang Ni, Hong Chang

Source: BMC Surgery, Vol 25, Iss 1, Pp 1-10 (2025)

Subject Terms: Laparoscopic pancreaticoduodenectomy, Clinically relevant postoperative pancreatic fistula, Postoperative complications, Machine learning, Predictive model, Surgery, RD1-811

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2482

Access URL: https://doaj.org/article/03fcc7e4071a4121bf60e586837ce9ea

Comprehensive landscape and oncogenic role of extrachromosomal circular DNA in malignant biliary strictures

Authors: Zhuo Cheng, Xuanmei Luo, Wenzheng Liu, Xiaofang Lu, Hong Chang, Yingchun Wang, Wei Zheng, Xiue Yan, Yonghui Huang

Source: Cell & Bioscience, Vol 15, Iss 1, Pp 1-14 (2025)

Subject Terms: Malignant biliary strictures, Bile cell-free extrachromosomal circular DNA, Diagnostic biomarkers, Liquid biopsy assay, Nanopore sequencing, Carcinogenesis, Biotechnology, TP248.13-248.65, Biology (General), QH301-705.5, Biochemistry, QD415-436

File Description: electronic resource

Relation: https://doaj.org/toc/2045-3701

Access URL: https://doaj.org/article/57498b64577e4e2f97314c5f970b9453

Identification of quality markers and mechanisms of Anzi Tiaochong Fang in the treatment of antiphospholipid syndrome-related recurrent pregnancy loss: chemical analysis, network pharmacology, and in vitro approaches

Authors: Shan He, Fei Ma, Jia Li, Da-yan Liu, Zhi-wei Wang, Peng-dian Chen, Jia-man Wu, Hong Chang, Yan Ning

Source: BMC Complementary Medicine and Therapies, Vol 25, Iss 1, Pp 1-17 (2025)

Subject Terms: Anzi tiaochong fang, Antiphospholipid syndrome-related recurrent pregnancy loss, HPLC-MS/MS, Quality markers, Network pharmacology, Mechanism, Other systems of medicine, RZ201-999

File Description: electronic resource

Relation: https://doaj.org/toc/2662-7671

Access URL: https://doaj.org/article/113f5950f9ae40a38f56f5ebf1444034

Evaluation of contralateral arterial flow compensation using transcranial Doppler in acute internal carotid artery occlusion and implications for neurological outcome

Authors: Yichen Wang, Hong Chang, Peng Bai, Jin Chen

Source: Scientific Reports, Vol 15, Iss 1, Pp 1-7 (2025)

Subject Terms: Transcranial Doppler, Collateral circulations, Malignant cerebral edema, Acute internal carotid artery occlusion, Modified Rankin Scale, Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/8b51b17328254ff4815e53b0b31ab2c0

Study on the load-supporting characteristic of the new type of support disc-type anchor under cyclic loading test

Authors: Fuguang Gu, Jun Wang, Hong Chang, Qinglin Sun, Zhengheng Gan, Haozhi Jiang

Source: Scientific Reports, Vol 15, Iss 1, Pp 1-17 (2025)

Subject Terms: Support disc-type anchor, Cyclic loading test, Load-supporting characteristic, Q-s curve, Functional model, Prediction of bearing capacity, Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/edd96534dff24f64acb032a56dbf58ef

Assessment of progression of pulmonary fibrosis based on metabonomics and analysis of intestinal microbiota

Authors: Jia-qi Liu, Hong-bing Zhou, Wan-fu Bai, Jia Wang, Qian Li, Li-ya Fan, Hong Chang, Song-li Shi

Source: Artificial Cells, Nanomedicine, and Biotechnology, Vol 52, Iss 1, Pp 201-217 (2024)

Subject Terms: Pulmonary fibrosis, disease progression, metabonomics, intestinal microbiota, biomarker, Biotechnology, TP248.13-248.65, Medical technology, R855-855.5

File Description: electronic resource

Relation: https://doaj.org/toc/2169-1401; https://doaj.org/toc/2169-141X

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Perturbed gut microbiota and serum metabolites are associated with progressive renal fibrosis

Authors: Run-Xi Wang, Hong-Bing Zhou, Jia-Xing Gao, Xing-Hua Li, Wan-Fu Bai, Jia Wang, Ying-Chun Bai, Li-Ya Fan, Hong Chang, Song-Li Shi

Source: Frontiers in Medicine, Vol 12 (2025)

Subject Terms: chronic kidney disease, renal fibrosis, disease progression, oxidative stress, inflammation, biochemical markers, Medicine (General), R5-920

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fmed.2025.1489100/full; https://doaj.org/toc/2296-858X

Access URL: https://doaj.org/article/2aa4dcc296e644fda8e0022436ffbaa5

Anti-synthetase syndrome with anti-PL-7 antibody positive in a child: a case report and literature review

Authors: Jia Liu, Nana Nie, Ranran Zhang, Dahai Wang, Yi Lin, Hong Chang

Source: Frontiers in Immunology, Vol 16 (2025)

Subject Terms: anti-synthetase syndrome, anti-PL-7 antibody, myositis, case report, ILD, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2025.1525432/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/f8c9ffe578644c519b00098bc3cd9327

Antibiotics in ambient fine particulate matter from two metropolitan cities in China: Characterization, source apportionment, and health risk assessment

Authors: Juan Liu, Qiao Yao, Wenyan Yan, Ke Fang, Runming He, Xiaona Wang, Yu’e Cha, Xiaoyan Yang, Wen Gu, Chao Wang, Yifu Lu, Mingyu Zhao, Yujie Ben, Kai Wang, Zhaomin Dong, Rong Zhang, Hong Chang, Song Tang

Source: Environment International, Vol 197, Iss , Pp 109340- (2025)

Subject Terms: Antibiotics, PM2.5, Source apportionment, Gaseous pollutants, Meteorological factors, Health risks, Environmental sciences, GE1-350

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0160412025000911; https://doaj.org/toc/0160-4120

Access URL: https://doaj.org/article/68645cc8c76045ff98ac865db0d28d40

Impact of secondary‐type mutations in acute myeloid leukemia with CEBPA mutation

Authors: Davidson Zhao, Musani Rumina, Mojgan Zarif, Cuihong Wei, Hong Chang

Source: eJHaem, Vol 5, Iss 6, Pp 1370-1372 (2024)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: https://doaj.org/toc/2688-6146

Access URL: https://doaj.org/article/46b524b09d21445bad6abe7384378bc0

Determining the Magic Wavelength Without Modulation of the Trap Depth

Authors: Jingjing Xia, Feng Guo, Yanhua Zhou, Xiaotong Lu, Hong Chang

Source: Optics, Vol 5, Iss 4, Pp 534-543 (2024)

Subject Terms: optical lattice clock, magic wavelength, AC Stark shift, Optics. Light, QC350-467, Applied optics. Photonics, TA1501-1820

File Description: electronic resource

Relation: https://www.mdpi.com/2673-3269/5/4/40; https://doaj.org/toc/2673-3269

Access URL: https://doaj.org/article/4132e3ae5e974c74a5944ca157464610

The associations between modifiable risk factors and constipation: a comprehensive mendelian randomization study

Authors: Hong Chang, Jing Ouyang, Meng Tian, Jin Yang, Jie Gao, Mengjiao Yang, Meng Zhang, Hao Yuan, Ya Zheng, Yuping Wang, Zhaofeng Chen

Source: BMC Gastroenterology, Vol 24, Iss 1, Pp 1-16 (2024)

Subject Terms: Constipation, Risk factors, Mendelian randomization, Genome-wide association data, Diseases of the digestive system. Gastroenterology, RC799-869

File Description: electronic resource

Relation: https://doaj.org/toc/1471-230X

Access URL: https://doaj.org/article/e362a4c1db5f4be5a69663de34b00384

NEK4 modulates circadian fluctuations of emotional behaviors and synaptogenesis in male mice

Authors: Zhi-Hui Yang, Xin Cai, Chu-Yi Zhang, Qing Zhang, Miao Li, Zhong-Li Ding, Yingqi Guo, Guolan Ma, Chao-Hao Yang, Lei Guo, Hong Chang, Chuang Wang, Ming Li, Xiao Xiao

Source: Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/8b50ce6ab81547c2a0e763b129773440

Determining diabetic kidney disease severity using traditional Chinese medicine syndrome classification

Authors: Amanda Yun Rui Lam, Huang Fang Zheng, Kok Keong Teo, Xiao Hui Xin, Chieh Suai Tan, Jean-Paul Kovalik, Sujoy Ghosh, Hong Chang Tan

Source: Singapore Medical Journal, Vol 65, Iss 9, Pp 519-524 (2024)

Subject Terms: Medicine

File Description: electronic resource

Relation: https://journals.lww.com/10.11622/smedj.2021179; https://doaj.org/toc/0037-5675; https://doaj.org/toc/2737-5935

Access URL: https://doaj.org/article/20ff674e60dc41b48714f5c45042cc16

Molecular point-of-care testing technologies: Current status and challenges

Authors: Yanbing Zu, Hong Chang, Zhanfeng Cui

Source: Nexus, Vol 2, Iss 2, Pp 100059- (2025)

Subject Terms: Science (General), Q1-390, Technology

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2950160125000063; https://doaj.org/toc/2950-1601

Access URL: https://doaj.org/article/081cab8aa51045d280d314f4d155a966

Web-Based, Algorithm-Guided Insulin Titration in Insulin-Treated Type 2 Diabetes: Pre-Post Intervention Study

Authors: Nishanth Thiagarajan, Hong Chang Tan, Suresh Rama Chandran, Phong Ching Lee, Yun Ann Chin, Wanling Zeng, Emily Tse Lin Ho, David Carmody, Su-Yen Goh, Yong Mong Bee

Source: JMIR Formative Research, Vol 9, Pp e68914-e68914 (2025)

Subject Terms: Medicine

File Description: electronic resource

Relation: https://formative.jmir.org/2025/1/e68914; https://doaj.org/toc/2561-326X

Access URL: https://doaj.org/article/7b2456a192df4760af27eda9f0d29646

Quality of Pancreatic Neuroendocrine Tumor Videos Available on TikTok and Bilibili: Content Analysis

Authors: Zheyu Niu, Yijie Hao, Faji Yang, Qirong Jiang, Yupeng Jiang, Shizhe Zhang, Xie Song, Hong Chang, Xu Zhou, Huaqiang Zhu, Hengjun Gao, Jun Lu

Source: JMIR Formative Research, Vol 8, Pp e60033-e60033 (2024)

Subject Terms: Medicine

File Description: electronic resource

Relation: https://formative.jmir.org/2024/1/e60033; https://doaj.org/toc/2561-326X

Access URL: https://doaj.org/article/3dd5cb56785b4c1c9f9a703ec6816303

A comparative metabolomic analysis reveals the metabolic variations among cartilage of Kashin-Beck disease and osteoarthritis

Authors: Hong Chang, Li Liu, Qingping Zhang, Gangyao Xu, Jianpeng Wang, Ping Chen, Cheng Li, Xianni Guo, Zhengjun Yang, Feng Zhang

Source: Bone & Joint Research, Vol 13, Iss 7, Pp 362-371 (2024)

Subject Terms: kashin-beck disease, osteoarthritis, cartilage, osteoarthritis (oa), cartilage tissue, cartilage damage, mass spectrometry, chromatography, dimethyl sulfoxide, total knee arthroplasty surgery, pathogenesis, t-tests, Diseases of the musculoskeletal system, RC925-935

File Description: electronic resource

Relation: https://doaj.org/toc/2046-3758

Access URL: https://doaj.org/article/057b7cdea71d4f83b6143e5f551ea96f

A selective review on statistical methods for massive data computation: distributed computing, subsampling, and minibatch techniques

Authors: Xuetong Li, Yuan Gao, Hong Chang, Danyang Huang, Yingying Ma, Rui Pan, Haobo Qi, Feifei Wang, Shuyuan Wu, Ke Xu, Jing Zhou, Xuening Zhu, Yingqiu Zhu, Hansheng Wang

Source: Statistical Theory and Related Fields, Vol 8, Iss 3, Pp 163-185 (2024)

Subject Terms: Distributed computing, massive data analysis, minibatch techniques, stochastic optimization, subsampling methods, Probabilities. Mathematical statistics, QA273-280

File Description: electronic resource

Relation: https://doaj.org/toc/2475-4269; https://doaj.org/toc/2475-4277

Access URL: https://doaj.org/article/88f77d041db947be8d00ebfb9ea8dcc2