Oncolytic virotherapy provides a potent therapy option for squamous bladder cancer.

Authors: Pannhausen, Julia, Wirtz, Julia, Mantwill, Klaus, Holm, Per-Sonne, Schwamborn, Kristina, Jonigk, Danny D., Gschwend, Jürgen E., Rose, Michael, Gaisa, Nadine T., Nawroth, Roman

Source: Scientific Reports; 4/18/2025, Vol. 15 Issue 1, p1-12, 12p

Methods for reversing multiple resistance in animal cells

Use of adenovirus and nucleic acids coding therefor

Use of adenovirus and nucleic acids coding therefor

Use of adenoviruses and nucleic acids that code for said viruses

Use of adenovirus and nucleic acids coding therefor

Development of an optimized, non‐stem cell line for intranasal delivery of therapeutic cargo to the central nervous system.

Authors: El‐Ayoubi, Ali, Arakelyan, Arsen, Klawitter, Moritz, Merk, Luisa, Hakobyan, Siras, Gonzalez‐Menendez, Irene, Quintanilla Fend, Leticia, Holm, Per Sonne, Mikulits, Wolfgang, Schwab, Matthias, Danielyan, Lusine, Naumann, Ulrike

Source: Molecular Oncology; Mar2024, Vol. 18 Issue 3, p528-546, 19p

YB-1-based oncolytic virotherapy in combination with CD47 blockade enhances phagocytosis of pediatric sarcoma cells.

Authors: von Ofen, Anna Josefine, Thiel, Uwe, Eck, Jennifer, Gassmann, Hendrik, Thiede, Melanie, Hauer, Julia, Holm, Per Sonne, Schober, Sebastian J.

Source: Frontiers in Oncology; 2024, p1-10, 10p

Subject Terms: ONCOLYTIC virotherapy, CD47 antigen, PHAGOCYTOSIS, LYSIS, SARCOMA

TCR-transgenic T cells and YB-1-based oncolytic virotherapy improve survival in a preclinical Ewing sarcoma xenograft mouse model.

Authors: Schober, Sebastian J., Thiede, Melanie, Gassmann, Hendrik, von Ofen, Anna Josefine, Knoch, Pia, Eck, Jennifer, Prexler, Carolin, Kordass-Wally, Corazon, Hauer, Julia, Burdach, Stefan, Holm, Per Sonne, Thiel, Uwe

Source: Frontiers in Immunology; 2024, p1-14, 14p

Subject Terms: ONCOLYTIC virotherapy, EWING'S sarcoma, T cells, LABORATORY mice, ANIMAL disease models

Intranasal Delivery of Oncolytic Adenovirus XVir-N-31 via Optimized Shuttle Cells Significantly Extends Survival of Glioblastoma-Bearing Mice.

Authors: El-Ayoubi, Ali, Klawitter, Moritz, Rüttinger, Jakob, Wellhäusser, Giulia, Holm, Per Sonne, Danielyan, Lusine, Naumann, Ulrike

Source: Cancers; Oct2023, Vol. 15 Issue 20, p4912, 16p

Subject Terms: BIOLOGICAL models, BRAIN, INJECTIONS, XENOGRAFTS, BLOOD-brain barrier, ANIMAL experimentation, VIRAL load, GLIOMAS, CANCER relapse, ADENOVIRUSES, TREATMENT effectiveness, CANCER patients, INTRANASAL administration, SURVIVAL analysis (Biometry), RESEARCH funding, CELL lines, ONCOLYTIC virotherapy, MICE, CELL death, EVALUATION

Effects of nanoparticle coatings on the activity of oncolytic adenovirus–magnetic nanoparticle complexes

Authors: Tresilwised, Nittaya, Pithayanukul, Pimolpan, Holm, Per Sonne, Schillinger, Ulrike, Plank, Christian, Mykhaylyk, Olga

Source: In Biomaterials 2012 33(1):256-269

Adenoviruses, nucleic acids coding therefor, and use thereof

Impact of radiation therapy on the oncolytic adenovirus dl520: Implications on the treatment of glioblastoma

Authors: Bieler, Alexa, Mantwill, Klaus, Holzmüller, Regina, Jürchott, Karsten, Kaszubiak, Alexander, Stärk, Sybille, Glockzin, Gabriel, Lage, Hermann, Grosu, Anca-Ligia, Gansbacher, Bernd, Holm, Per Sonne

Source: In Radiotherapy and Oncology 2008 86(3):419-427

Adenoviruses, nucleic acids that code for the same and the use of said viruses

Regulation of MDR1 gene expression in multidrug-resistant cancer cells is independent from YB-1

Authors: Kaszubiak, Alexander, Kupstat, Annette, Müller, Ursula, Hausmann, Romy, Holm, Per Sonne, Lage, Hermann

Source: In Biochemical and Biophysical Research Communications 25 May 2007 357(1):295-301

Adenoviral systems and the uses thereof

E1-MINUS ADENOVIRUSES AND USE THEREOF

METHODS FOR REVERSING MULTIPLE RESISTANCE IN ANIMAL CELLS

NOVEL USE OF ADENOVIRUSES AND NUCLEIC ACIDS THAT CODE FOR SAID VIRUSES

USE OF ADENOVIRUS AND NUCLEIC ACIDS CODING THEREFOR