Limited clinical activity of palbociclib and ribociclib monotherapy in advanced cancers with cyclin D‐CDK4/6 pathway alterations in the Dutch DRUP and Australian MoST trials

Authors: Zeverijn, Laurien J., Looze, Eleonora J., Thavaneswaran, Subotheni, Berge Henegouwen, J. Maxime, Simes, Robert J., Hoes, Louisa R., Sjoquist, Katrin M., Wijngaart, Hanneke, Sebastian, Lucille, Geurts, Birgit S., Lee, Chee K., Wit, Gijsbrecht F., Espinoza, David, Roepman, Paul, Lin, Frank P., Jansen, Anne M. L., Leng, Wendy W. J., Noort, Vincent, Leek, Lindsay V. M., Vos, Filip Y. F. L., Herpen, Carla M. L., Gelderblom, Hans, Verheul, Henk M. W., Thomas, David M., Voest, Emile E.

Source: International journal of cancer. 153(7):1413-1422

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100192727357.0x000001&indx=1&recIds=ETOCvdc_100192727357.0x000001

Characterization of discordance between mismatch repair deficiency and microsatellite instability testing may prevent inappropriate treatment with immunotherapy.

Authors: Geurts, Birgit S, Zeverijn, Laurien J, van Berge Henegouwen, Jade M, van der Wijngaart, Hanneke, Hoes, Louisa R, de Wit, Gijs F, Spiekman, Ilse AC, Battaglia, Thomas W, van Beek, Daphne M, Roepman, Paul, Jansen, Anne ML, de Leng, Wendy WJ, Broeks, Annegien, Labots, Mariette, van Herpen, Carla ML, Gelderblom, Hans, Verheul, Henk MW, Snaebjornsson, Petur, Voest, Emile E

Source: Journal of Pathology; Jul2024, Vol. 263 Issue 3, p288-299, 12p

Subject Terms: HEREDITARY nonpolyposis colorectal cancer, WHOLE genome sequencing, MICROSATELLITE repeats, IMMUNOTHERAPY, IMMUNE checkpoint proteins

Study protocol: Whole genome sequencing Implementation in standard Diagnostics for Every cancer patient (WIDE)

Authors: Samsom, Kris G., Bosch, Linda J. W., Schipper, Luuk J., Roepman, Paul, de Bruijn, Ewart, Hoes, Louisa R., Riethorst, Immy, Schoenmaker, Lieke, van der Kolk, Lizet E., Retèl, Valesca P., Frederix, Geert W. J., Buffart, Tineke E., van der Hoeven, Jacobus J. M., Voest, Emile E., Cuppen, Edwin, Monkhorst, Kim, Meijer, Gerrit A.

Source: BMC medical genomics. 13(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100186590977.0x000001&indx=1&recIds=ETOCvdc_100186590977.0x000001

Efficacy, safety and biomarker analysis of durvalumab in patients with mismatch-repair deficient or microsatellite instability-high solid tumours.

Authors: Geurts, Birgit S., Battaglia, Thomas W., van Berge Henegouwen, J. Maxime, Zeverijn, Laurien J., de Wit, Gijs F., Hoes, Louisa R., van der Wijngaart, Hanneke, van der Noort, Vincent, Roepman, Paul, de Leng, Wendy W. J., Jansen, Anne M. L., Opdam, Frans L., de Jonge, Maja J. A., Cirkel, Geert A., Labots, Mariette, Hoeben, Ann, Kerver, Emile D., Bins, Adriaan D., Erdkamp, Frans G.L., van Rooijen, Johan M.

Source: BMC Cancer; 3/4/2023, Vol. 23 Issue 1, p1-14, 14p

Subject Terms: MICROSATELLITE repeats, FRAMESHIFT mutation, PROGRESSION-free survival, BIOMARKERS, HEREDITARY nonpolyposis colorectal cancer, SURVIVAL rate

Codon-specific KRASmutations predict survival benefit of trifluridine/tipiracil in metastatic colorectal cancer

Authors: van de Haar, Joris, Ma, Xuhui, Ooft, Salo N., van der Helm, Pim W., Hoes, Louisa R., Mainardi, Sara, Pinato, David J., Sun, Kristi, Salvatore, Lisa, Tortora, Giampaolo, Zurlo, Ina Valeria, Leo, Silvana, Giampieri, Riccardo, Berardi, Rossana, Gelsomino, Fabio, Merz, Valeria, Mazzuca, Federica, Antonuzzo, Lorenzo, Rosati, Gerardo, Stavraka, Chara, Ross, Paul, Rodriquenz, Maria Grazia, Pavarana, Michele, Messina, Carlo, Iveson, Timothy, Zoratto, Federica, Thomas, Anne, Fenocchio, Elisabetta, Ratti, Margherita, Depetris, Ilaria, Cergnul, Massimiliano, Morelli, Cristina, Libertini, Michela, Parisi, Alessandro, De Tursi, Michele, Zanaletti, Nicoletta, Garrone, Ornella, Graham, Janet, Longarini, Raffaella, Gobba, Stefania Maria, Petrillo, Angelica, Tamburini, Emiliano, La Verde, Nicla, Petrelli, Fausto, Ricci, Vincenzo, Wessels, Lodewyk F. A., Ghidini, Michele, Cortellini, Alessio, Voest, Emile E., Valeri, Nicola

Source: Nature Medicine; March 2023, Vol. 29 Issue: 3 p605-614, 10p

Limited evolution of the actionable metastatic cancer genome under therapeutic pressure

Authors: van de Haar, Joris, Hoes, Louisa R., Roepman, Paul, Lolkema, Martijn P., Verheul, Henk M. W., Gelderblom, Hans, de Langen, Adrianus J., Smit, Egbert F., Cuppen, Edwin, Wessels, Lodewyk F. A., Voest, Emile E.

Source: Nature Medicine; September 2021, Vol. 27 Issue: 9 p1553-1563, 11p

Caring for patients with cancer in the COVID-19 era

Authors: van de Haar, Joris, Hoes, Louisa R., Coles, Charlotte E., Seamon, Kenneth, Fröhling, Stefan, Jäger, Dirk, Valenza, Franco, de Braud, Filippo, De Petris, Luigi, Bergh, Jonas, Ernberg, Ingemar, Besse, Benjamin, Barlesi, Fabrice, Garralda, Elena, Piris-Giménez, Alejandro, Baumann, Michael, Apolone, Giovanni, Soria, Jean Charles, Tabernero, Josep, Caldas, Carlos, Voest, Emile E.

Source: Nature Medicine; May 2020, Vol. 26 Issue: 5 p665-671, 7p

Author Correction: Caring for patients with cancer in the COVID-19 era

Authors: van de Haar, Joris, Hoes, Louisa R., Coles, Charlotte E., Seamon, Kenneth, Fröhling, Stefan, Jäger, Dirk, Valenza, Franco, de Braud, Filippo, De Petris, Luigi, Bergh, Jonas, Ernberg, Ingemar, Besse, Benjamin, Barlesi, Fabrice, Garralda, Elena, Piris-Giménez, Alejandro, Baumann, Michael, Apolone, Giovanni, Soria, Jean Charles, Tabernero, Josep, Caldas, Carlos, Voest, Emile E.

Source: Nature Medicine; July 2020, Vol. 26 Issue: 7 p1146-1146, 1p

This result is not displayed to guests.
Login for full access.