CD3 aptamers promote expansion and persistence of tumor-reactive T cells for adoptive T cell therapy in cancer

Authors: Ashwathi Puravankara Menon, Helena Villanueva, Daniel Meraviglia-Crivelli, Hisse M. van Santen, Joschka Hellmeier, Angelina Zheleva, Francesca Nonateli, Timo Peters, Tassilo L.A. Wachsmann, Mercedes Hernandez-Rueda, Johannes B. Huppa, Gerhard J. Schütz, Eva Sevcsik, Beatriz Moreno, Fernando Pastor

Source: Molecular Therapy: Nucleic Acids, Vol 35, Iss 2, Pp 102198- (2024)

Subject Terms: MT: Oligonucleotides: Therapies and Applications, CD3, aptamer, cancer immunotherapy, adoptive T cell therapy, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2162253124000854; https://doaj.org/toc/2162-2531

Access URL: https://doaj.org/article/6c3ef753dfa94901b0ef2480454cb96e

Decreased breadth of the antibody response to the spike protein of SARS-CoV-2 after repeated vaccination

Authors: Lydia Horndler, Pilar Delgado, Salvador Romero-Pinedo, Marina Quesada, Ivaylo Balabanov, Rocío Laguna-Goya, Patricia Almendro-Vázquez, Miguel A. Llamas, Manuel Fresno, Estela Paz-Artal, Hisse M. van Santen, Stela Álvarez-Fernández, Asunción Olmo, Balbino Alarcón

Source: Frontiers in Immunology, Vol 14 (2023)

Subject Terms: SARS-CoV-2, S protein, flow cytometry method, vaccines, antibody breadth, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2023.1157263/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/3d10bd0d76d84b00a2b085b5449fd50b

ACE2 Serum Levels as Predictor of Infectability and Outcome in COVID-19

Authors: María del Carmen Maza, María Úbeda, Pilar Delgado, Lydia Horndler, Miguel A. Llamas, Hisse M. van Santen, Balbino Alarcón, David Abia, Laura García-Bermejo, Sergio Serrano-Villar, Ugo Bastolla, Manuel Fresno

Source: Frontiers in Immunology, Vol 13 (2022)

Subject Terms: COVID-19, ACE2, antibodies, neutralization, biomarker, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2022.836516/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/6e2e21cd90034b56abde7ebc99f67520

Inmunoterapia con células CAR-T en hematooncología pediátrica

Authors: Isabel Mirones, Lucas Moreno, Ana Patiño-García, Garbiñe Lizeaga, José M. Moraleda, María Luisa Toribio, Antonio Pérez-Martínez, Luisa Sisinni, Marina García-Morín, Javier Anguita, Manuel Ramírez, Miguel Ángel Díaz, Marta González, Laura Alonso, Susana Rives, Marta M. Alonso, Pilar Palomo, Jaime Verdú-Amorós, Isabel Martínez, Pilar Guerra-García, José Luis Fuster, Andrés Sánchez-Salinas, Miguel Blanquer, Javier García-Castro, Hisse M. van Santen, Pablo Menéndez

Source: Anales de Pediatría, Vol 93, Iss 1, Pp 59.e1-59.e10 (2020)

Subject Terms: Immunotherapy, CAR-T cells, Cancer, Advanced therapies, Pediatrics, RJ1-570

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1695403320300163; https://doaj.org/toc/1695-4033

Access URL: https://doaj.org/article/16b70437e8b54743b3869661ec601c68

Immunotherapy with CAR-T cells in paediatric haematology-oncology

Authors: Isabel Mirones, Lucas Moreno, Ana Patiño-García, Garbiñe Lizeaga, José M. Moraleda, María Luisa Toribio, Antonio Pérez-Martínez, Luisa Sisinni, Marina García-Morín, Javier Anguita, Manuel Ramírez, Laura Alonso, Susana Rives, Marta M. Alonso, Pilar Palomo, Jaime Verdú-Amorós, Isabel Martínez, Pilar Guerra-García, José Luis Fuster, Andrés Sánchez-Salinas, Miguel Blanquer, Javier García-Castro, María Luisa Toribio e Hisse M. van Santen, Pablo Menéndez

Source: Anales de Pediatría (English Edition), Vol 93, Iss 1, Pp 59.e1-59.e10 (2020)

Subject Terms: Inmunoterapia, Células CAR-T, Cáncer, Terapias avanzadas, Pediatrics, RJ1-570

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S234128792030082X; https://doaj.org/toc/2341-2879

Access URL: https://doaj.org/article/04aef7bb483e4a4c9a790ec0154f9c37

Receptor pre-clustering and T cell responses: insights into molecular mechanisms

Authors: Mario eCastro, Hisse M van Santen, María eFerez, Balbino eAlarcón, Grant D Lythe, Carmen eMolina-Paris

Source: Frontiers in Immunology, Vol 5 (2014)

Subject Terms: signalling, T cell receptor, clustering, memory T cells, stochastic dynamics, naive T cells, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: http://journal.frontiersin.org/Journal/10.3389/fimmu.2014.00132/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/21fc69da5bc947e99caec54ac45be808

Flow cytometry multiplexed method for the detection of neutralizing human antibodies to the native SARS‐CoV‐2 spike protein

Authors: Lydia Horndler, Pilar Delgado, David Abia, Ivaylo Balabanov, Pedro Martínez‐Fleta, Georgina Cornish, Miguel A Llamas, Sergio Serrano‐Villar, Francisco Sánchez‐Madrid, Manuel Fresno, Hisse M van Santen, Balbino Alarcón

Source: EMBO Molecular Medicine, Vol 13, Iss 3, Pp 1-15 (2021)

Subject Terms: flow cytometry, method, S protein, SARS‐CoV‐2, seropositivity, Medicine (General), R5-920, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1757-4676; https://doaj.org/toc/1757-4684

Access URL: https://doaj.org/article/b7331f174c224189a4735789612de0d0

Models of self-peptide sampling by developing T cells identify candidate mechanisms of thymic selection.

Authors: Iren Bains, Hisse M van Santen, Benedict Seddon, Andrew J Yates

Source: PLoS Computational Biology, Vol 9, Iss 7, p e1003102 (2013)

Subject Terms: Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3723501?pdf=render; https://doaj.org/toc/1553-734X; https://doaj.org/toc/1553-7358

Access URL: https://doaj.org/article/15ddf4fa2f904eb799ec8433efb133b7