Anti-CX3CL1 (fractalkine) monoclonal antibody attenuates lung and skin fibrosis in sclerodermatous graft-versus-host disease mouse model

Authors: Takumi Hasegawa, Akira Utsunomiya, Takenao Chino, Hiroshi Kasamatsu, Tomomi Shimizu, Takashi Matsushita, Takashi Obara, Naoto Ishii, Hideaki Ogasawara, Wataru Ikeda, Toshio Imai, Noritaka Oyama, Minoru Hasegawa

Source: Arthritis Research & Therapy, Vol 26, Iss 1, Pp 1-13 (2024)

Subject Terms: 3 ~ 10, CX3CL1, CXCR1, Fibrosis, Fractalkine, Graft-versus-host disease, Diseases of the musculoskeletal system, RC925-935

File Description: electronic resource

Relation: https://doaj.org/toc/1478-6362

Access URL: https://doaj.org/article/3acc19c6429048e2b0f2a8a57b9bde78

GWAS for systemic sclerosis identifies six novel susceptibility loci including one in the Fcγ receptor region

Authors: Yuki Ishikawa, Nao Tanaka, Yoshihide Asano, Masanari Kodera, Yuichiro Shirai, Mitsuteru Akahoshi, Minoru Hasegawa, Takashi Matsushita, Kazuyoshi Saito, Sei-ichiro Motegi, Hajime Yoshifuji, Ayumi Yoshizaki, Tomohiro Kohmoto, Kae Takagi, Akira Oka, Miho Kanda, Yoshihito Tanaka, Yumi Ito, Kazuhisa Nakano, Hiroshi Kasamatsu, Akira Utsunomiya, Akiko Sekiguchi, Hiroaki Niiro, Masatoshi Jinnin, Katsunari Makino, Takamitsu Makino, Hironobu Ihn, Motohisa Yamamoto, Chisako Suzuki, Hiroki Takahashi, Emi Nishida, Akimichi Morita, Toshiyuki Yamamoto, Manabu Fujimoto, Yuya Kondo, Daisuke Goto, Takayuki Sumida, Naho Ayuzawa, Hidetoshi Yanagida, Tetsuya Horita, Tatsuya Atsumi, Hirahito Endo, Yoshihito Shima, Atsushi Kumanogoh, Jun Hirata, Nao Otomo, Hiroyuki Suetsugu, Yoshinao Koike, Kohei Tomizuka, Soichiro Yoshino, Xiaoxi Liu, Shuji Ito, Keiko Hikino, Akari Suzuki, Yukihide Momozawa, Shiro Ikegawa, Yoshiya Tanaka, Osamu Ishikawa, Kazuhiko Takehara, Takeshi Torii, Shinichi Sato, Yukinori Okada, Tsuneyo Mimori, Fumihiko Matsuda, Koichi Matsuda, Tiffany Amariuta, Issei Imoto, Keitaro Matsuo, Masataka Kuwana, Yasushi Kawaguchi, Koichiro Ohmura, Chikashi Terao

Source: Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/2821292baef747248e9e487cef06ad07

A case of refractory peripheral neuropathy associated with eosinophilic granulomatosis with polyangiitis with successful tapering of systemic corticosteroid and reduced dosing frequency of high-dose intravenous immunoglobulin after combined use of mepolizumab

Authors: Kentaro Kawate, Hiroshi Kasamatsu, Kentarou Nishimura, Yoriko Muneishi, Wataru Takashima, Haruka Koizumi, Shiro Iino, Kouji Hayashi, Noritaka Oyama, Minoru Hasegawa

Source: Journal of Cutaneous Immunology and Allergy, Vol 7 (2024)

Subject Terms: peripheral neuropathy, eosinophilic granulomatosis with polyangiitis, mepolizumab, intravenous immunoglobulin, corticosteroid therapy, Dermatology, RL1-803, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontierspartnerships.org/articles/10.3389/jcia.2024.12776/full; https://doaj.org/toc/2574-4593

Access URL: https://doaj.org/article/94814deca2c045d7ba5c79b17b968ff9

A cysteine proteinase inhibitor ALLN alleviates bleomycin-induced skin and lung fibrosis

Authors: Hiroshi Kasamatsu, Takenao Chino, Takumi Hasegawa, Natsuko Utsunomiya, Akira Utsunomiya, Masami Yamada, Noritaka Oyama, Minoru Hasegawa

Source: Arthritis Research & Therapy, Vol 25, Iss 1, Pp 1-17 (2023)

Subject Terms: Systemic sclerosis, Skin, Lung, Calpain, Cysteine proteinase inhibitor, TGF-β, Diseases of the musculoskeletal system, RC925-935

File Description: electronic resource

Relation: https://doaj.org/toc/1478-6362

Access URL: https://doaj.org/article/51df41483b5541e2986fc73015c4703e

A case of refractory hypertrophic lupus erythematosus on the face whose irreversible skin fibrosis was treated by local full‐thickness skin graft under disease control with a combined use of topical and systemic immunosuppressants, and hydroxychloroquine

Authors: Shiori Sekine, Shiro Iino, Kentaro Nishimura, Sayuri Okamura, Hiroshi Kasamatsu, Noritaka Oyama, Kouichiro Hirai, Minoru Hasegawa

Source: Journal of Cutaneous Immunology and Allergy, Vol 6, Iss 2, Pp 63-65 (2023)

Subject Terms: Dermatology, RL1-803, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://doaj.org/toc/2574-4593

Access URL: https://doaj.org/article/5144c1d7791f4fa689c691e69a5a47f2

The compound LG283 inhibits bleomycin-induced skin fibrosis via antagonizing TGF-β signaling

Authors: Akira Utsunomiya, Takenao Chino, Hiroshi Kasamatsu, Takumi Hasegawa, Natsuko Utsunomiya, Vu Huy Luong, Takashi Matsushita, Yoko Sasaki, Dai Ogura, Shin-ichiro Niwa, Noritaka Oyama, Minoru Hasegawa

Source: Arthritis Research & Therapy, Vol 24, Iss 1, Pp 1-15 (2022)

Subject Terms: Systemic sclerosis, Fibrosis, Vascular injury, Therapy, Mouse model, TGF-β, Diseases of the musculoskeletal system, RC925-935

File Description: electronic resource

Relation: https://doaj.org/toc/1478-6362

Access URL: https://doaj.org/article/b68308a6286e442d85d4b00233c720ac

Retrospective evaluation of the utility of two-step surgery for facial basal cell carcinoma and squamous cell carcinoma

Authors: Shiro Iino, Natsuki Baba, Takumi Hasegawa, Hiroshi Kasamatsu, Noritaka Oyama, Takahiro Tokunaga, Minoru Hasegawa

Source: Frontiers in Surgery, Vol 9 (2022)

Subject Terms: facial skin cancers, basal cell carcinoma, squamous cell carcinoma, two-step surgery, dermal regeneration template, Surgery, RD1-811

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fsurg.2022.915731/full; https://doaj.org/toc/2296-875X

Access URL: https://doaj.org/article/db0836913c7b43849a39ff106c527b44

Bullous pemphigoid receiving a novel long‐acting dipeptidyl‐peptidase‐4 (DPP‐4) inhibitor omarigliptin in a patient with type 2 diabetes: A case report

Authors: Hiroshi Kasamatsu, Takenao Chino, Noritaka Oyama, Takakiyo Nakaya, Minoru Hasegawa

Source: Journal of Cutaneous Immunology and Allergy, Vol 4, Iss 4, Pp 89-91 (2021)

Subject Terms: anti‐BP180‐NC16a autoantibody, autoimmune bullous disease, bullous pemphigoid, dipeptidyl‐peptidase‐4 inhibitor, omarigliptin, Dermatology, RL1-803, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://doaj.org/toc/2574-4593

Access URL: https://doaj.org/article/12a7ff4d63894838ad4218439e34b9af

A rare case of cutaneous vasculitis with diagnostic difficulty in coexistence of serum anti‐PR3 antibody and in vivo IgA deposits in the skin

Authors: Hiroshi Kasamatsu, Haruka Koizumi, Miki Honda, Yuka Yamaguchi, Takenao Chino, Noritaka Oyama, Minoru Hasegawa

Source: Journal of Cutaneous Immunology and Allergy, Vol 3, Iss 2, Pp 37-38 (2020)

Subject Terms: Dermatology, RL1-803, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://doaj.org/toc/2574-4593

Access URL: https://doaj.org/article/b59852be8d134753932cec798e9bcebb

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