Stratification according to autoantibody status in systemic sclerosis reveals distinct molecular signatures

Authors: Rouvière, Bénedicte ¹, Le Dantec, Christelle ¹, Bettacchioli, Eleonore ¹, Beretta, Lorenzo ², Foulquier, Nathan ¹, Cao, Celine ¹, Jamin, Christophe ¹, Pers, Jacques-Olivier ¹, Kerick, Martin ³, Martin, Javier ^{4, 5}, Alarcón-Riquelme, Marta Eugenia ^{6, 7}, de Moreuil, Claire ⁸, Cornec, Divi ¹, Hillion, Sophie ^{1, *}

Source: In Annals of the Rheumatic Diseases March 2025 84(3):480-490

Identification of the central tolerance checkpoint for autoreactive proteinase 3+ B cells in human bone marrow

Authors: Berti, Alvise ^{a, b, c}, Tomasi, Michele ^c, Pesce, Isabella ^d, Lista, Enrico ^e, Guella, Anna ^e, Bortolotti, Roberto ^a, Paolazzi, Giuseppe ^a, Hillion, Sophie ^f, Specks, Ulrich ^{g, ⁎}, Grandi, Guido ^{b, c}, Cornec, Divi ^{f, ⁎⁎}

Source: In Journal of Autoimmunity December 2024 149

Phenotypic, transcriptomic, and spatial characterization of CD45RB+ naïve mature B cells: Implications in Sjögren's disease

Authors: Boudigou, Marina, Frutoso, Marie, Hémon, Patrice, Le Dantec, Christelle, Chatzis, Loukas, Devauchelle, Valérie, Jamin, Christophe, Cornec, Divi, Pers, Jacques-Olivier, Le Pottier, Laëtitia, Hillion, Sophie

Source: In Clinical Immunology November 2024 268

Autoreactive Plasmablasts After B Cell Depletion With Rituximab and Relapses in Antineutrophil Cytoplasmic Antibody–Associated Vasculitis

Authors: Berti, Alvise, Hillion, Sophie, Konig, Maximilian F., Moura, Marta Casal, Hummel, Amber M., Carmona, Eva, Peikert, Tobias, Fervenza, Fernando C., Kallenberg, Cees G.M., Langford, Carol A., Merkel, Peter A., Monach, Paul A., Seo, Philip, Spiera, Robert F., Brunetta, Paul, St. Clair, E. William, Harris, Kristina M., Stone, John H., Grandi, Guido, Pers, Jacques‐Olivier, Specks, Ulrich, Cornec, Divi

Source: Arthritis & rheumatology. 75(5):736-747

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100181599868.0x000001&indx=1&recIds=ETOCvdc_100181599868.0x000001

Safety and pharmacokinetics of Roscovitine (Seliciclib) in cystic fibrosis patients chronically infected with Pseudomonas aeruginosa, a randomized, placebo-controlled study

Authors: Meijer, Laurent, Hery-Arnaud, Geneviève, Leven, Cyril, Nowak, Emmanuel, Hillion, Sophie, Renaudineau, Yves, Durieu, Isabelle, Chiron, Raphaël, Prevotat, Anne, Fajac, Isabelle, Hubert, Dominique, Murris-Espin, Marlène, Huge, Sandrine, Danner-Boucher, Isabelle, Ravoninjatovo, Bruno, Leroy, Sylvie, Macey, Julie, Urban, Thierry, Rault, Gilles, Mottier, Dominique, Berre, Rozenn Le

Source: Journal of cystic fibrosis. 21(3):529-536

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100163970972.0x000001&indx=1&recIds=ETOCvdc_100163970972.0x000001

The diversity of the plasmablast signature across species and experimental conditions: A meta‐analysis

Authors: Grasseau, Alexis, Boudigou, Marina, Michée‐Cospolite, Magalie, Delaloy, Céline, Mignen, Olivier, Jamin, Christophe, Cornec, Divi, Pers, Jacques‐Olivier, Le Pottier, Laëtitia, Hillion, Sophie

Source: Immunology. 164(1):120-134

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100127325727.0x000001&indx=1&recIds=ETOCvdc_100127325727.0x000001

Abatacept Promotes Regulatory B Cell Functions, Enhancing Their Ability to Reduce the Th1 Response in Rheumatoid Arthritis Patients through the Production of IL-10 and TGF-β

Authors: Alegria, Guillermo Carvajal, Cornec, Divi, Saraux, Alain, Devauchelle-Pensec, Valérie, Jamin, Christophe, Hillion, Sophie, Pers, Jacques-Olivier, Pochard, Pierre

Source: Journal of immunology. 207(2):470-482

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A Proinflammatory Cytokine Network Profile in Th1/Type 1 Effector B Cells Delineates a Common Group of Patients in Four Systemic Autoimmune Diseases

Authors: Simon, Quentin, Grasseau, Alexis, Boudigou, Marina, Le Pottier, Laëtitia, Bettachioli, Eléonore, Cornec, Divi, Rouvière, Bénédicte, Jamin, Christophe, Le Lann, Lucas, Borghi, Maria Orietta, Aguilar‐Quesada, Rocio, Renaudineau, Yves, Alarcón‐Riquelme, Marta E., Pers, Jacques‐Olivier, Hillion, Sophie, Beretta, L., Aguilar‐Quesada, R., Aguirre‐Zamorano, M. A., Callejas Rubio, J. L., Castro‐Villegas, M. C., Cervera, R., Chizzolini, C., Collantes, E., Cornec, D., De Langhe, E., Devauchelle‐Pensec, V., Escudero‐Contreras, A., Espinosa, G., Fernández Roldán, M. C., Gomes Anjos, T., Hiepe, F., Jiménez Moleón, I., Jousse‐Joulin, S., Lauwerys, B., López‐Berrio, A., Lories, R., Marovac, J., Meroni, P. L., Miranda, B., Navarro‐Linares, H., Ortega‐Castro, R., Ortego, N., Pers, J. O., Ramón Garrido, E., Raya, E., Ríos Fernández, R., Rodríguez‐Pintó, I., Saraux, A., Jamin, C., Marañón, C., Le Lann, L., Varela, N., Muchmore, B., Dufour, A. M., Alvarez, M., Montserrat, C., Barbarroja, N., Lopez‐Pedrera, C., Gerl, V., De Groof, A., Ducreux, J., Trombetta, E., Li, T., Alvarez‐Errico, D., Rao, S.

Source: Arthritis & rheumatology. 73(8):1550-1561

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100124848919.0x000001&indx=1&recIds=ETOCvdc_100124848919.0x000001

The Innate Part of the Adaptive Immune System

Authors: Hillion, Sophie, Arleevskaya, Marina I., Blanco, Patrick, Bordron, Anne, Brooks, Wesley H., Cesbron, Jean Yves, Kaveri, Srini, Vivier, Eric, Renaudineau, Yves

Source: Clinical reviews in allergy & immunology. 58(2):151-154

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100164274199.0x000001&indx=1&recIds=ETOCvdc_100164274199.0x000001

Complement System: a Neglected Pathway in Immunotherapy

Authors: Bordron, Anne, Bagacean, Cristina, Tempescul, Adrian, Berthou, Christian, Bettacchioli, Eléonore, Hillion, Sophie, Renaudineau, Yves

Source: Clinical reviews in allergy & immunology. 58(2):155-171

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100164274187.0x000001&indx=1&recIds=ETOCvdc_100164274187.0x000001

Maf expression in B cells restricts reactive plasmablast and germinal center B cell expansion.

Authors: Hillion, Sophie, Miranda, Anjelica, Le Dantec, Christelle, Boudigou, Marina, Le Pottier, Laëtitia, Cornec, Divi, Torres, Raul M., Pelanda, Roberta

Source: Nature Communications; 9/12/2024, Vol. 15 Issue 1, p1-16, 16p

Subject Terms: B cell differentiation, PLASMA cells, B cells, TRANSCRIPTION factors, IMMUNOLOGIC memory

Stability study and external quality assessment scheme implementation for complement components dosage on EDTA plasma

Authors: Lopez, Benjamin, Rogeau, Stéphanie, Deleplancque, Anne-Sophie, Moitrot, Emmanuelle, Berthe, Ericka, Goulvestre, Claire, Hillion, Sophie, Vinner, Elisabeth, Labalette, Myriam, Dubucquoi, Sylvain

Source: Annales de biologie clinique. 77(6):669-680

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN622453507&indx=1&recIds=ETOCRN622453507

Innate B Cells: the Archetype of Protective Immune Cells

Authors: Grasseau, Alexis, Boudigou, Marina, Le Pottier, Laëtitia, Chriti, Nedra, Cornec, Divi, Pers, Jacques-Olivier, Renaudineau, Yves, Hillion, Sophie

Source: Clinical reviews in allergy & immunology. 58(1):92-106

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100128552239.0x000001&indx=1&recIds=ETOCvdc_100128552239.0x000001

Association of Combined Anti‐Ro52/TRIM21 and Anti‐Ro60/SSA Antibodies With Increased Sjögren Disease Severity Through Interferon Pathway Activation.

Authors: Bettacchioli, Eléonore, Saraux, Alain, Tison, Alice, Cornec, Divi, Dueymes, Maryvonne, Foulquier, Nathan, Hillion, Sophie, Roguedas‐Contios, Anne‐Marie, Benyoussef, Anas‐Alexis, Alarcon‐Riquelme, Marta E., Pers, Jacques‐Olivier, Devauchelle‐Pensec, Valérie, Beretta, Lorenzo, Vigone, Barbara, Jousse‐Joulin, Sandrine, Lauwerys, Bernard, Ducreux, Julie, Maudoux, Anne‐Lise, Vasconcelos, Carlos, Tavares, Ana

Source: Arthritis & Rheumatology; May2024, Vol. 76 Issue 5, p751-762, 12p

Subject Terms: RNA analysis, LEUCOPENIA, RESEARCH funding, AUTOANTIBODIES, IMMUNOGLOBULINS, LYMPHOPENIA, CELLULAR signal transduction, SEVERITY of illness index, DESCRIPTIVE statistics, BLOOD sedimentation, INTERFERONS, LONGITUDINAL method, HYPERGAMMAGLOBULINEMIA, GENE expression profiling, ARTHRITIS, SJOGREN'S syndrome, INFLAMMATION, BIOMARKERS, SEQUENCE analysis, SYMPTOMS

Geographic Terms: EUROPE

In-depth characterization of CD24highCD38high transitional human B cells reveals different regulatory profiles

Authors: Simon, Quentin, Pers, Jacques-Olivier, Cornec, Divi, Le Pottier, Laëtitia, Mageed, Rizgar A., Hillion, Sophie

Source: In The Journal of Allergy and Clinical Immunology May 2016 137(5):1577-1584

Diagnostic criteria for autoimmune neutropenia

Authors: Youinou, Pierre, Jamin, Christophe, Le Pottier, Laëtitia, Renaudineau, Yves, Hillion, Sophie, Pers, Jacques-Olivier

Source: In Autoimmunity Reviews April-May 2014 13(4-5):574-576

B cells display an abnormal distribution and an impaired suppressive function in patients with chronic antibody–mediated rejection

Authors: Nouël, Alexandre ⁶, Ségalen, Isabelle ⁶, Jamin, Christophe, Doucet, Laurent, Caillard, Sophie, Renaudineau, Yves, Pers, Jacques-Olivier ^*, Le Meur, Yannick ⁷, Hillion, Sophie ⁷

Source: In Kidney International March 2014 85(3):590-599

Intravenous immunoglobulin induces a functional silencing program similar to anergy in human B cells

Authors: Séïté, Jean-François, Goutsmedt, Carole, Youinou, Pierre, Pers, Jacques-Olivier, Hillion, Sophie

Source: In The Journal of Allergy and Clinical Immunology January 2014 133(1):181-188

TLR9 responses of B cells are repressed by intravenous immunoglobulin through the recruitment of phosphatase

Authors: Séité, Jean-François, Guerrier, Thomas, Cornec, Divi, Jamin, Christophe, Youinou, Pierre, Hillion, Sophie

Source: In Journal of Autoimmunity 2011 37(3):190-197

The regulatory capacity of B cells directs the aggressiveness of CLL

Authors: Mohr, Audrey, Cumin, Marie, Bagacean, Cristina, Pochard, Pierre, Le Dantec, Christelle, Hillion, Sophie, Renaudineau, Yves, Berthou, Christian, Tempescul, Adrian, Saad, Hussam, Pers, Jacques-Olivier, Bordron, Anne, Jamin, Christophe

Source: Oncoimmunology. 8(3)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100089568066.0x000001&indx=1&recIds=ETOCvdc_100089568066.0x000001