Predicting T cell receptor functionality against mutant epitopes

Authors: Drost, Felix ^{1, 2, 10}, Dorigatti, Emilio ^{1, 3, 4, 10}, Straub, Adrian ^{5, 10}, Hilgendorf, Philipp ^{5, 6}, Wagner, Karolin I. ⁵, Heyer, Kersten ⁵, López Montes, Marta ⁵, Bischl, Bernd ^{3, 4}, Busch, Dirk H. ^{5, 7, 11}, Schober, Kilian ^{5, 6, 8, 11}, Schubert, Benjamin ^{1, 9, 11, 12, ∗}

Source: In Cell Genomics 11 September 2024 4(9)

HLA reduction of human T cells facilitates generation of immunologically multicompatible cellular products

Authors: Winterhalter, Pascal M., Warmuth, Linda, Hilgendorf, Philipp, Schütz, Julius M., Dötsch, Sarah, Tonn, Torsten, Cicin-Sain, Luka, Busch, Dirk H., Schober, Kilian

Source: In Blood Advances 9 July 2024 8(13):3416-3426

Recruitment of epitope-specific T cell clones with a low-avidity threshold supports efficacy against mutational escape upon re-infection

Authors: Straub, Adrian, Grassmann, Simon, Jarosch, Sebastian, Richter, Lena, Hilgendorf, Philipp, Hammel, Monika, Wagner, Karolin I., Buchholz, Veit R., Schober, Kilian, Busch, Dirk H.

Source: In Immunity 13 June 2023 56(6):1269-1284

DNA methylation profiling identifies TBKBP1 as potent amplifier of cytotoxic activity in CMV-specific human CD8⁺ T cells.

Authors: Yu, Zheng¹, Sasidharan-Nair, Varun¹, Buchta, Thalea^2,3, Bonifacius, Agnes^4,5, Khan, Fawad^6,7, Pietzsch, Beate¹, Ahmadi, Hosein¹, Beckstette, Michael¹, Niemz, Jana¹, Hilgendorf, Philipp⁸, Mausberg, Philip⁴, Keller, Andreas^9,10, Falk, Christine^5,11, Busch, Dirk H.^12,13, Schober, Kilian^8,14, Cicin-Sain, Luka^5,6,7, Müller, Fabian¹⁵, Brinkmann, Melanie M.^2,3, Eiz-Vesper, Britta^4,5, Floess, Stefan¹

Source: PLoS Pathogens; 9/26/2024, Vol. 20 Issue 9, p1-30, 30p

HLA reduction of human T cells facilitates generation of immunologically multi-compatible cellular products

Authors: Winterhalter, Pascal M., Warmuth, Linda, Hilgendorf, Philipp, Schütz, Julius M., Dötsch, Sarah, Tonn, Torsten, Cicin-Sain, Luka, Busch, Dirk H., Schober, Kilian

Source: Blood Advances; 20240101, Issue: Preprints