Efficacy and safety of upadacitinib maintenance therapy for moderately to severely active ulcerative colitis in patients responding to 8 week induction therapy (U-ACHIEVE Maintenance): overall results from the randomised, placebo-controlled, double-blind, phase 3 maintenance study

Authors: Vermeire, Séverine ^{a, *}, Danese, Silvio ^b, Zhou, Wen ^c, Ilo, Dapo ^c, Klaff, Justin ^c, Levy, Gweneth ^c, Yao, Xuan ^c, Chen, Su ^c, Sanchez Gonzalez, Yuri ^c, Hébuterne, Xavier ^d, Lindsay, James O ^e, Higgins, Peter D R ^f, Cao, Qian ^g, Nakase, Hiroshi ^h, Colombel, Jean-Frédéric ⁱ, Loftus, Edward V, Jr ^j, Panaccione, Remo ^k

Source: In The Lancet Gastroenterology & Hepatology November 2023 8(11):976-989

Etrolizumab versus adalimumab or placebo as induction therapy for moderately to severely active ulcerative colitis (HIBISCUS): two phase 3 randomised, controlled trials

Authors: Rubin, David T, Dotan, Iris, DuVall, Aaron, Bouhnik, Yoram, Radford-Smith, Graham, Higgins, Peter D R, Mishkin, Daniel S, Arrisi, Pablo, Scalori, Astrid, Oh, Young S, Tole, Swati, Chai, Akiko, Chamberlain-James, Kirsten, Lacey, Stuart, McBride, Jacqueline, Panés, Julian

Source: Lancet.Gastroenterology & hepatology. 7(1):17-27

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100183255131.0x000001&indx=1&recIds=ETOCvdc_100183255131.0x000001

Upadacitinib as induction and maintenance therapy for moderately to severely active ulcerative colitis: results from three phase 3, multicentre, double-blind, randomised trials

Authors: Danese, Silvio, Vermeire, Séverine, Zhou, Wen, Pangan, Aileen L, Siffledeen, Jesse, Greenbloom, Susan, Hébuterne, Xavier, D'Haens, Geert, Nakase, Hiroshi, Panés, Julian, Higgins, Peter D R, Juillerat, Pascal, Lindsay, James O, Loftus, Edward V, Sandborn, William J, Reinisch, Walter, Chen, Min-Hu, Sanchez Gonzalez, Yuri, Huang, Bidan, Xie, Wangang, Liu, John, Weinreich, Michael A, Panaccione, Remo

Source: Lancet. 399(10341):2113-2128

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100169154618.0x000001&indx=1&recIds=ETOCvdc_100169154618.0x000001

Impact of SARS-CoV-2 Vaccination on Inflammatory Bowel Disease Activity and Development of Vaccine-Related Adverse Events: Results From PREVENT-COVID

Authors: Weaver, Kimberly N, Zhang, Xian, Dai, Xiangfeng, Watkins, Runa, Adler, Jeremy, Dubinsky, Marla C, Kastl, Arthur, Bousvaros, Athos, Strople, Jennifer A, Cross, Raymond K, Higgins, Peter D R, Ungaro, Ryan C, Bewtra, Meenakshi, Bellaguarda, Emanuelle, Farraye, Francis A, Boccieri, Margie E, Firestine, Ann, Kappelman, Michael D, Long, Millie D

Source: Inflammatory bowel diseases. 28(10):1497-1505

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100165290412.0x000001&indx=1&recIds=ETOCvdc_100165290412.0x000001

Inflammatory Bowel Disease Risk Variants Are Associated with an Increased Risk of Skin Cancer

Authors: Cushing, Kelly C, Du, Xiaomeng, Chen, Yanhua, Stetson, L C, Kuppa, Annapurna, Chen, Vincent L, Kahlenberg, J Michelle, Gudjonsson, Johann E, Vanderwerff, Brett, Higgins, Peter D R, Speliotes, Elizabeth K

Source: Inflammatory bowel diseases. 28(11):1667-1676

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100163909875.0x000001&indx=1&recIds=ETOCvdc_100163909875.0x000001

Efficacy of Ustekinumab in Crohn's Disease With and Without Concurrent Autoimmune Skin Disease

Authors: Fradkov, Elena, Sheehan, Jessica, Cushing, Kelly, Higgins, Peter D R

Source: Inflammatory bowel diseases. 28(6):895-904

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100161569138.0x000001&indx=1&recIds=ETOCvdc_100161569138.0x000001

Effect of ABT-263 on Intestinal Fibrosis in Human Myofibroblasts, Human Intestinal Organoids, and the Mouse Salmonella typhimurium Model

Authors: Johnson, Laura A, Rodansky, Eva S, Tran, Anhdao, Collins, Stephen G, Eaton, Kathryn A, Malamet, Benjamin, Steiner, Calen A, Huang, Sha, Spence, Jason R, Higgins, Peter D R

Source: Inflammatory bowel diseases. 28(2):161-175

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100139940520.0x000001&indx=1&recIds=ETOCvdc_100139940520.0x000001

Disparities in Vaccination Amongst Socially Vulnerable Patients with Inflammatory Bowel Disease.

Authors: Sheehan, Jessica L., Jordan, Ariel A., Newman, Kira L., Johnson, Laura A., Eloubeidi, Dala, Cohen-Mekelburg, Shirley, Berinstein, Jeffrey A., Tipirneni, Renuka, Higgins, Peter D. R.

Source: Digestive Diseases & Sciences; Jan2025, Vol. 70 Issue 1, p136-145, 10p

Subject Terms: CROHN'S disease, INFLAMMATORY bowel diseases, MEDICAL care, PUBLIC health, PREVENTIVE health services

Etrolizumab versus adalimumab or placebo as induction therapy for moderately to severely active ulcerative colitis (HIBISCUS): two phase 3 randomised, controlled trials

Authors: Rustem, Abdulkhakov, Norasiah, Abu Bakar, Humberto, Aguilar, Diego, Aizenberg, Hale, Akpinar, Evangelos, Akriviadis, Olga, Alexeeva, Bagdadi, Alikhanov, Andres, Alvarisqueta, Ashwin, Ananthakrishnan, Jane, Andrews, Tomasz, Arlukowicz, Nathan, Atkinson, Ozlen, Atug, Mauro, Bafutto, Jozef, Balaz, George, Bamias, Marko, Banic, Andrey, Baranovsky, Guerino, Barbalaco Neto, Metin, Basaranoglu, Curtis, Baum, Stefan, Baydanov, William, Bennetts, Fatih, Besisik, Sudhir, Bhaskar, Andrzej, Bielasik, Leonid, Bilianskyi, Bahri, Bilir, Pavol, Blaha, Verle, Bohman, Julia, Borissova, Vladimir, Borzan, Francisco, Bosques-Padilla, Yoram, Bouhnik, James, Brooker, Tetiana, Budko, Igor, Budzak, Ivan, Bunganic, Jonathon, Chapman, Azlida, Che' Aun, Tatiana, Chernykh, Michael, Chiorean, Ivan, Chopey, Dimitrios, Christodoulou, Pui Shan, Chu, Galina, Chumakova, Andrew, Cummins, Robert, Cunliffe, Mirjana, Cvetkovic, Ulku, Dagli, Wit Cezary, Danilkiewicz, Olena, Datsenko, Carlos Fernando, de Magalhães Francesconi, Henry, Debinski, Elena, Deminova, Jelena, Derova, John Nik, Ding, Julia, Dmitrieva, Oleg, Dolgikh, Tomas, Douda, Piotr, Drobinski, Gerald, Dryden, Pedro, Duarte Gaburri, George Aaron, DuVall, Mikhail, Dvorkin, Craig, Ennis, Yusuf, Erzin, Galyna, Fadieienko, Oleksandr, Fediv, Olga, Fedorishina, Miroslav, Fedurco, Roland, Fejes, Jorge, Fernandez, Monica Lorena, Fernandez, Lucky, Flores, Bradley, Freilich, Keith, Friedenberg, Sergio, Fuster, Beata, Gawdis-Wojnarska, Fabio Leonel, Gil Parada, Edgardo Daniel, Gimenez, Nataliia, Golovchenko, Oleksandr, Golovchenko, Maciej, Gonciarz, Can, Gonen, Glenn, Gordon, Milos, Gregus, Vladimir, Grinevich, Rogelio, Guajardo Rodriguez, Stephen, Hall, John, Hanson, Marek, Hartleb, Xavier, Hebuterne, Peter, Hendy, Robert, Herring, David, Hetzel, Peter, Higgins, Raouf, Hilal, Ida Normiha, Hilmi, Tibor, Hlavaty, Richard, Holman, Gerald, Holtmann, John, Hong, Frantisek, Horvath, Ihor, Hospodarskyy, Irena, Hrstic, Sadettin, Hulagu, Luis Alberto, Ibarra Verdugo, Ikechukwu, Ibegbu, Stephen, Inns, Vladimir, Ivashkin, James, Izanec, Rajesh, Jain, Zofia, Jamrozik-Kruk, Victor, Kamburov, John, Karagiannis, Tarkan, Karakan, Marek, Karczewski, Irina, Kasherininova, Seymour, Katz, Barry, Kaufman, Edita, Kazenaite, Irina, Kholina, Sunil, Khurana, Jaroslaw, Kierkus, Anzela, Kiselevska, Dariusz, Kleczkowski, Volodymyr, Klymenko, Slavko, Knezevic, Malgorzata, Kondusz-Szklarz, Natalya, Korablina, Bartosz, Korczowski, Lyubomir, Kosturkov, Iskren, Kotzev, Georgios, Kouklakis, Ioannis, Koutroubakis, Richard, Krause, Ian, Kronborg, Miodrag, Krstic, Zeljko, Krznaric, Mikolaj, Krzyzanowski, Grazyna, Kulig, Karin, Kull, Limas, Kupcinskas, Mark, Lamet, Tatjana, Latinovic Radakovic, Rupert, Leong, Wai Keung, Leung, Henry, Levine, Michael Kin Kong, Li, Lúcia, Libanez Bessa Campelo Braga, Maria, Livzan, Tetiana, Lohdanidi, Maria Helena, Louzada Pereira, John, Lowe, Kresimir, Luetic, Milan, Lukas, Yurii, Lymar, Finlay, Macrae, Anu, Mäelt, Igor, Maev, Arkadiusz, Mamos, Gerasimos, Mantzaris, Benno, Margus, Ivanka, Marinova, Inna, Markevych, Mario, Markov, Srdjan, Markovic, Juan Ricardo, Marquez Velasquez, Felipe, Mazzoleni, Konstantinos, Mimidis, Brent, Mitchell, Gregory, Moore, Luis Alonso, Morales Garza, Salvatore, Moscatello, Yuriy, Mostovoy, Reme, Mountifield, Aleksandar, Nagorni, Viacheslav, Neshta, Andrey, Obrezan, Oleksandr, Oliinyk, Genoile, Oliveira Santana Silva, Maria, Orzeszko, Vladimir, Pavlenko, Dimitar, Pavlov, Mariana, Penkova, Sasa, Peric, Plamen, Petkov, Asen, Petrov, Plamen, Petrov, Michaela, Petrova, Raymond, Phillips, Sergio, Pintor Chacon, Igor, Polianskyi, Ludmyla, Prystupa, Mykhailo, Pugach, Ana Teresa, Pugas Carvalho, Aldis, Pukitis, Jiri, Pumprla, Volodymyr, Pyrogovskyy, Istvan, Racz, Graham, Radford-Smith, Raja Affendi, Raja Ali, Daniel, Ramos Castañeda, Odery, Ramos Júnior, David, Rausher, Andrey, Rebrov, Jaroslaw, Regula, Amir, Rezk, Viktoriia, Reznikova, Iaroslava, Rishko, Xavier, Roblin, Grigory, Rodoman, Carlos Arturo, Rojas Rodriguez, Jerzy, Rozciecha, David, Rubin, Maciej, Rupinski, Jacek, Rzucidlo, Oleg, Sablin, Halil, Sahin, Rosemi, Salleh, Douglas, Samuel, Antonio, Scafuto Scotton, Robert, Schnabel, Michael, Schulman, Michael, Schultz, John, Scott, Shahriar, Sedghi, Ahmad, Shaban, Marina, Shapina, Natalia, Shaposhnikova, Oksana, Shchukina, Alex, Sherman, Irina, Shumikhina, Vladimir, Simanenkov, Vladislav, Simonov, Giedrius, Simulionis, Igor, Skrypnyk, Zbigniew, Sliwowski, Jan, Smid, Mahmood, Solaiman, Najm, Soofi, Konstantinos, Soufleris, Zoia, Spassova, Mykola, Stanislavchuk, Krystyna, Stec-Michalska, Jonathas, Stifft, Simeon, Stoinov, Girgina, Stoyanova, Keith, Sultan, Lindsey, Surace, Dimitar, Takov, Jaak, Tälli, Ludmila, Tankova, Hugo, Tanno, Dino, Tarabar, Elias, Tarakji, Konstantin, Tchernev, Hoi Poh, Tee, Lena, Thin, Carlton, Thomas, Irina, Tishaeva, Tsveta, Todorova, Oleksandr, Tokarenko, Ivars, Tolmanis, Ratko, Tomasevic, Vasiliy, Trofimov, Zsolt, Tulassay, Belkis, Unsal, Alma, Uzunova-Genova, John, Valentine, Ekaterina, Valuyskikh, Eduardo, Vasconcellos, Galina, Vasileva, Sergiy, Vasylyuk, Byron, Vaughn, Francisco, Velazquez, Vadym, Vizir, Borislav, Vladimirov, Miroslava, Volfova, Petr, Vyhnalek, Ian, Wallace, Marek, Waluga, William, Watkins, John, Weber, Anna, Wiechowska-Kozlowska, Nathaniel, Winstead, Pawel, Wojtkiewicz, Barbara, Wozniak-Stolarska, Bruce, Yacyshyn, Alexey, Yakovlev, Ziad, Younes, Lígia, Yukie Sassaki, Ilhami, Yuksel, Jan, Zachar, Cyrla, Zaltman, Natasa, Zdravkovic Petrovic, Vyacheslav, Zhdan, Maryna, Zinchenko, Maciej, Zymla, Rubin, David T ^*, Dotan, Iris ^*, DuVall, Aaron, Bouhnik, Yoram, Radford-Smith, Graham, Higgins, Peter D R, Mishkin, Daniel S, Arrisi, Pablo, Scalori, Astrid, Oh, Young S, Tole, Swati, Chai, Akiko, Chamberlain-James, Kirsten, Lacey, Stuart, McBride, Jacqueline, Panés, Julian ^*

Source: In The Lancet Gastroenterology & Hepatology January 2022 7(1):17-27

Variations in Health Care Utilization Patterns Among Inflammatory Bowel Disease Patients at Risk for High Medical Service Utilization Enrolled in High Deductible Health Plans

Authors: Berinstein, Jeffrey A, Cohen-Mekelburg, Shirley A, Steiner, Calen A, McLeod, Megan, Noureldin, Mohamed, Allen, John I, Kullgren, Jeffrey T, Waljee, Akbar K, Higgins, Peter D R

Source: Inflammatory bowel diseases. 27(6):771-778

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100161618008.0x000001&indx=1&recIds=ETOCvdc_100161618008.0x000001

Trends of 5-Aminosalicylate Medication Use in Patients With Crohn Disease

Authors: Noureldin, Mohamed, Cohen-Mekelburg, Shirley, Mahmood, Asadullah, Stidham, Ryan, Higgins, Peter D R, Govani, Shail, Deshpande, Amar R, Waljee, Akbar K

Source: Inflammatory bowel diseases. 27(4):516-521

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100161613028.0x000001&indx=1&recIds=ETOCvdc_100161613028.0x000001

AXL Is a Potential Target for the Treatment of Intestinal Fibrosis

Authors: Steiner, Calen A, Rodansky, Eva S, Johnson, Laura A, Berinstein, Jeffrey A, Cushing, Kelly C, Huang, Sha, Spence, Jason R, Higgins, Peter D R

Source: Inflammatory bowel diseases. 27(3):303-316

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100161612818.0x000001&indx=1&recIds=ETOCvdc_100161612818.0x000001

Endoscopic and Histological Assessment, Correlation, and Relapse in Clinically Quiescent Ulcerative Colitis (MARQUEE)

Authors: Osterman, Mark T, Scott, Frank I, Fogt, Franz F, Gilroy, Erin D, Parrott, Susan, Galanko, Joseph, Cross, Raymond, Moss, Alan, Herfarth, Hans H, Higgins, Peter D R

Source: Inflammatory bowel diseases. 27(2):207-214

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100135741097.0x000001&indx=1&recIds=ETOCvdc_100135741097.0x000001

User guide for Social Determinants of Health Survey data in the All of Us Research Program.

Authors: Koleck, Theresa A¹, Dreisbach, Caitlin^2,3, Zhang, Chen², Grayson, Susan¹, Lor, Maichou⁴, Deng, Zhirui¹, Conway, Alex¹, Higgins, Peter D R⁵, Bakken, Suzanne^6,7,8

Source: Journal of the American Medical Informatics Association; Dec2024, Vol. 31 Issue 12, p3032-3041, 10p

Extended Induction and Prognostic Indicators of Response in Patients Treated with Mirikizumab with Moderately to Severely Active Ulcerative Colitis in the LUCENT Trials.

Authors: D'Haens, Geert, Higgins, Peter D R, Peyrin-Biroulet, Laurent, Sands, Bruce E, Lee, Scott, Moses, Richard E, Redondo, Isabel, Escobar, Rodrigo, Gibble, Theresa Hunter, Keohane, Anthony, Morris, Nathan, Zhang, Xin, Arora, Vipin, Kobayashi, Taku

Source: Inflammatory Bowel Diseases; Dec2024, Vol. 30 Issue 12, p2335-2346, 12p

Use of Upadacitinib in 16 Tofacitinib-refractory Ulcerative Colitis Patients: A Single-center Case 2Series.

Authors: Levine, Jake, McKibbin, Jey, Ham, Rebecca, Cohen-Mekelburg, Shirley, Bishu, Shrinivas, Tang, Kevin, Higgins, Peter D R, Berinstein, Jeffrey A

Source: Inflammatory Bowel Diseases; Nov2024, Vol. 30 Issue 11, p2232-2235, 4p

Self-Efficacy, Patient Activation, and the Burden of Inflammatory Bowel Disease on Patients' Daily Lives.

Authors: Sheehan, Jessica L., Greene-Higgs, LaVana, Resnicow, Kenneth, Patel, Minal R., Barnes, Edward L., Waljee, Akbar K., Higgins, Peter D. R., Cohen-Mekelburg, Shirley

Source: Digestive Diseases & Sciences; Nov2024, Vol. 69 Issue 11, p4089-4097, 9p

Subject Terms: CROHN'S disease, PATIENT participation, INFLAMMATORY bowel diseases, PATIENT Activation Measure, ULCERATIVE colitis

Legalization of Cannabis Does Not Reduce Opioid Prescribing in Patients With Inflammatory Bowel Disease: A Difference-in-Difference Analysis.

Authors: Noureldin, Mohamed, Van, Tony, Cohen-Mekelburg, Shirley, Scott, Frank I., Higgins, Peter D. R., Stidham, Ryan W., Hou, Jason, Waljee, Akbar K., Berinstein, Jeffrey A.

Source: American Journal of Gastroenterology (Lippincott Williams & Wilkins); Oct2024, Vol. 119 Issue 10, p2130-2133, 4p

Are Depression and Anxiety Underdiagnosed in Socially Vulnerable Patients With Inflammatory Bowel Disease?

Authors: Sheehan, Jessica L, Jordan, Ariel A, Newman, Kira L, Johnson, Laura A, Eloubeidi, Dala, Cohen-Mekelburg, Shirley, Berinstein, Jeffrey A, Tipirneni, Renuka, Higgins, Peter D R

Source: Inflammatory Bowel Diseases; Oct2024, Vol. 30 Issue 10, p1696-1706, 11p

Understanding the Perspectives and Experiences of Patients with Acute Severe Ulcerative Colitis in the Hospital: A Qualitative Analysis.

Authors: Romain, Dustin, Larson, Charlotte, Kathuria, Priya, Aintabi, Daniel, Tedesco, Nicholas, Saunyama, Queen, DeJonckheere, Melissa, Bishu, Shrinivas, Cohen-Mekelburg, Shirley, Higgins, Peter D. R., Berinstein, Jeffrey A.

Source: Digestive Diseases & Sciences; Oct2024, Vol. 69 Issue 10, p3690-3700, 11p

Subject Terms: INFLAMMATORY bowel diseases, ULCERATIVE colitis, PATIENTS' attitudes, PATIENT experience, THEMATIC analysis