Effects of Melatonin on Brain's Glymphatic System and Cell Hypoxia in Mice with a Genetically Determined Model of Type II Diabetes Mellitus

Authors: Michurina, Svetlana V., Serykh, Anastasia E., Ishchenko, Irina Yu., Arkhipova, Valentina V., Arkhipov, Sergey A., Zavjalov, Evgeny L.

Source: 2024 IEEE International Multi-Conference on Engineering, Computer and Information Sciences (SIBIRCON) Multi-Conference on Engineering, Computer and Information Sciences (SIBIRCON), 2024 IEEE International. :253-256 Sep, 2024

Relation: 2024 IEEE International Multi-Conference on Engineering, Computer and Information Sciences (SIBIRCON)

Recent Update of Natural Compounds as HIF-1α Inhibitors in Colorectal Carcinoma

Authors: Pandey P, Lakhanpal S, Mahmood D, Baldaniya L, Kang HN, Hwang S, Kang S, Choi M, Moon S, Pandey S, Chaudhary K, Khan F, Kim B

Source: Drug Design, Development and Therapy, Vol Volume 19, Pp 2017-2034 (2025)

Subject Terms: hif-1α, colorectal cancer, natural compounds, inhibitors, hypoxia, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.dovepress.com/recent-update-of-natural-compounds-as-hif-1-inhibitors-in-colorectal-c-peer-reviewed-fulltext-article-DDDT; https://doaj.org/toc/1177-8881

Access URL: https://doaj.org/article/0822a104ef0246e888bde6ab83d332bd

Sirtuin1 mitigates hypoxia-induced cardiomyocyte apoptosis in myocardial infarction via PHD3/HIF-1α

Authors: Yafen Chen, Shuyao Shan, Qiqi Xue, Yan Ren, Qihong Wu, Jiawei Chen, Ke Yang, Jiumei Cao

Source: Molecular Medicine, Vol 31, Iss 1, Pp 1-14 (2025)

Subject Terms: Acute myocardial infarction, Apoptosis, Hypoxia, Sirt1, Phd3, Hif-1α, Therapeutics. Pharmacology, RM1-950, Biochemistry, QD415-436

File Description: electronic resource

Relation: https://doaj.org/toc/1528-3658

Access URL: https://doaj.org/article/dc133a9c99bc46a5a36db54ed53012cd

Therapeutic potential of total flavonoids of Rhizoma Drynariae: inhibiting adipogenesis and promoting osteogenesis via MAPK/HIF-1α pathway in primary osteoporosis

Authors: Hui Su, Luyao Liu, Zechen Yan, WenXuan Guo, Guangxin Huang, Rujie Zhuang, Yu Pan

Source: Journal of Orthopaedic Surgery and Research, Vol 20, Iss 1, Pp 1-17 (2025)

Subject Terms: Rhizoma drynariae (Drynaria fortunei J. Smith), Total flavonoids, Osteoporosis, MAPK, HIF-1α, Adipogenesis, Orthopedic surgery, RD701-811, Diseases of the musculoskeletal system, RC925-935

File Description: electronic resource

Relation: https://doaj.org/toc/1749-799X

Access URL: https://doaj.org/article/6ca54502ff6c4d63891a2405370bbbc0

Effects of hypoxia stress on the milk synthesis in bovine mammary epithelial cells

Authors: Yanshan Jin, Zhuolin Liu, Ziyan Yang, Lizhu Fang, Feng-Qi Zhao, Hongyun Liu

Source: Journal of Animal Science and Biotechnology, Vol 16, Iss 1, Pp 1-18 (2025)

Subject Terms: Hypoxic stress, HIF-1α, Low oxygen, Milk synthesis, Animal culture, SF1-1100, Veterinary medicine, SF600-1100

File Description: electronic resource

Relation: https://doaj.org/toc/2049-1891

Access URL: https://doaj.org/article/f9a5dcab3a5944148e9f14923da3388c

Relationship between MRI features and HIF-1α, GLUT1 and Ki-67 expression in pituitary adenoma with cystic degeneration

Authors: Fangfang Zhang, Zhenhong Pan, Jianwu Wu, Yinxing Huang

Source: BMC Medical Imaging, Vol 25, Iss 1, Pp 1-8 (2025)

Subject Terms: Pituitary adenoma, Fluid level, GLUT1, HIF-1α, Ki-67, Medical technology, R855-855.5

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2342

Access URL: https://doaj.org/article/71cfcf79f0bd4be68bdce992f0bba88b

Lactate accumulation from HIF-1α-mediated PMN-MDSC glycolysis restricts brain injury after acute hypoxia in neonates

Authors: Xiaogang Zhang, Laiqin Peng, Shuyi Kuang, Tianci Wang, Weibin Wu, Shaowen Zuo, Chunling Chen, Jiaxiu Ye, Guilang Zheng, Yuxiong Guo, Yumei He

Source: Journal of Neuroinflammation, Vol 22, Iss 1, Pp 1-26 (2025)

Subject Terms: Fetal intrauterine distress, Polymorphonuclear myeloid-derived suppressor cells, HIF-1α, Glycolysis, Lactate, Microglial activation, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: https://doaj.org/toc/1742-2094

Access URL: https://doaj.org/article/e42287157d50486f91b1073a1d0d0536

The HIF-1α/miR-145b/Angpt2 axis attenuates renal fibrosis induced by unilateral renal ischemia–reperfusion

Authors: Bingyou Cheng, Shang Huang, Lin Zhou, Pei Zhu, Zhongpu Li, Liang Hu, Jingsong Liu, Kejian Zhu

Source: Renal Replacement Therapy, Vol 11, Iss 1, Pp 1-11 (2025)

Subject Terms: Renal fibrosis, miR-145b, HIF-1α, Angpt2, Unilateral renal ischemia–reperfusion, Diseases of the genitourinary system. Urology, RC870-923

File Description: electronic resource

Relation: https://doaj.org/toc/2059-1381

Access URL: https://doaj.org/article/4db25ca0f3e24ea885dd3d567e2f0d52

Antioxidant and Anti-Inflammatory Potential of Cymbopogon nardus Ethanol Extract on 3T3-L1 Cells

Authors: Rohmawaty E, Wiraswati HL, Zahra TA, Amalina SN, Ramadhanti J, Rosdianto AM, Laelalugina A, Nasution GTD, Kamisah Y

Source: Journal of Inflammation Research, Vol Volume 18, Pp 2125-2136 (2025)

Subject Terms: ros, il-6, cox-2, hif-1α, menadione, lipopolysaccharide, Pathology, RB1-214, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.dovepress.com/antioxidant-and-anti-inflammatory-potential-of-cymbopogon-nardus-ethan-peer-reviewed-fulltext-article-JIR; https://doaj.org/toc/1178-7031

Access URL: https://doaj.org/article/2398d425d50a4eedabea55c6b2b29b81

The role of lipids in promoting hair growth through HIF-1 signaling pathway

Authors: Jieun Seo, Kotone Matsumoto, Ayaka Nanmo, Shan Tu, Do-Won Jeong, Yang-Sook Chun, Lei Yan, Tatsuto Kageyama, Junji Fukuda

Source: Scientific Reports, Vol 15, Iss 1, Pp 1-8 (2025)

Subject Terms: Hair growth, Lipids, HIF-1α, Dermal papilla cells, Hair follicle organoids, Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/ba3de585429c4adf8376155f7b4ac595

Elucidating the Role of HIF-1α/YAP Signaling Pathway in Regulating Inflammation in Human Periodontal Stem Cells: An in vitro Study

Authors: Zhao HW, Liu ST, Wang XJ, Zhang XM, Ma X

Source: Journal of Inflammation Research, Vol Volume 18, Pp 1875-1886 (2025)

Subject Terms: periodontitis, hif-1α, yap, dmog, inflammation, Pathology, RB1-214, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.dovepress.com/elucidating-the-role-of-hif-1yap-signaling-pathway-in-regulating-infla-peer-reviewed-fulltext-article-JIR; https://doaj.org/toc/1178-7031

Access URL: https://doaj.org/article/506c83ccf64a43328dafa2fdf6ae14a7

Mechanism of hyperbaric oxygen therapy downregulating H-type angiogenesis in subchondral bone of knee osteoarthritis through the PHD2/HIF-1α pathway

Authors: Jianjian Wang, Wen Yu, Yuxin Zhang, Bo Chen, Zhaoxiang Meng

Source: Journal of Orthopaedic Surgery and Research, Vol 20, Iss 1, Pp 1-10 (2025)

Subject Terms: Hyperbaric oxygen therapy, Osteoarthritis, PHD2, HIF-1α, Angiogenesis, Orthopedic surgery, RD701-811, Diseases of the musculoskeletal system, RC925-935

File Description: electronic resource

Relation: https://doaj.org/toc/1749-799X

Access URL: https://doaj.org/article/f7468cbc60a340268eed672df252ec44

Senescence-related circRNA circHIF-1α is associated with pancreatic cancer progression

Authors: Hao Hua, Yazu Deng, Dijie Zheng, Changhao Wu, Liwen Chen, Binbin Shi, Zhiwei He, Chao Yu

Source: Cancer Cell International, Vol 25, Iss 1, Pp 1-19 (2025)

Subject Terms: Pancreatic cancer, circHIF-1α, Senescence, HIF-1α, HUR, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282, Cytology, QH573-671

File Description: electronic resource

Relation: https://doaj.org/toc/1475-2867

Access URL: https://doaj.org/article/c2488856669d46cab6e703b0fcf966bf

Mechanistic insights into gut microbe derived siderophores and PHD2 interactions with implications for HIF-1α stabilization

Authors: Jainabbi Irshad Ahmed Patel, Jagadeesha Poyya, Apeksha Padakannaya, Namrata Manjunath Kurdekar, Ajay Sathayanarayan Khandagale, Chandrashekhar Gajanan Joshi, Santosh R. Kanade, Kapaettu Satyamoorthy

Source: Scientific Reports, Vol 15, Iss 1, Pp 1-15 (2025)

Subject Terms: Ischemia, Hypoxia, HIF-1α signaling, Gut microbiota, Siderophores, Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/2337761933e94dbb913d11337fe37c25

Myocardial mRNA expression of interleukin-6 and hypoxia inducible factor-1α in neonates with congenital cardiac defects

Authors: Nesrine Farhat, Jaime Vazquez-Jimenez, Ruth Heying, Marie-Christine Seghaye

Source: Molecular and Cellular Pediatrics, Vol 11, Iss 1, Pp 1-8 (2024)

Subject Terms: IL-6, HIF-1α, Gene expression, Myocardium, Neonates, Congenital heart disease, Pediatrics, RJ1-570

File Description: electronic resource

Relation: https://doaj.org/toc/2194-7791

Access URL: https://doaj.org/article/8ed46a39dc014521a5b8814b92666590

Zhishi Xiebai Guizhi Decoction modulates hypoxia and lipid toxicity to alleviate pulmonary vascular remodeling of pulmonary hypertension in rats

Authors: Min Fu, Yuan Li, Jingjing Liu, Junjie Liu, Jiaoxia Wei, Yuxin Qiao, Hanxin Zhong, Dongyang Han, Haitao Lu, Li Yao

Source: Chinese Medicine, Vol 19, Iss 1, Pp 1-18 (2024)

Subject Terms: Zhishi Xiebai Guizhi Decoction, Pulmonary hypertension, Pulmonary vascular remodeling, Chemical compounds, HIF-1α, Other systems of medicine, RZ201-999

File Description: electronic resource

Relation: https://doaj.org/toc/1749-8546

Access URL: https://doaj.org/article/8ac7e8140d38407fba47876b205e4303

Evaluation of Antifibrotic Mechanisms of 3′5-Dimaleamylbenzoic Acid on Idiopathic Pulmonary Fibrosis: A Network Pharmacology and Molecular Docking Analysis

Authors: Karina González-García, Jovito Cesar Santos-Álvarez, Juan Manuel Velázquez-Enríquez, Cecilia Zertuche-Martínez, Edilburga Reyes-Jiménez, Rafael Baltiérrez-Hoyos, Verónica Rocío Vásquez-Garzón

Source: Drugs and Drug Candidates, Vol 3, Iss 4, Pp 860-878 (2024)

Subject Terms: apoptosis, maleimide, pro-oxidants, PI3K-Akt, HIF-1α, fibroblasts, Pharmacy and materia medica, RS1-441, Chemistry, QD1-999

File Description: electronic resource

Relation: https://www.mdpi.com/2813-2998/3/4/48; https://doaj.org/toc/2813-2998

Access URL: https://doaj.org/article/2ea42d65b637499a851982911b3feef7

Exosomes derived from umbilical cord mesenchymal stem cells promote healing of complex perianal fistulas in rats

Authors: Yafei Lu, Shaohua Huangfu, Chuanxue Ma, Yan Ding, Yajie Zhang, Chungen Zhou, Lianming Liao, Ming Li, Jia You, Yuting Chen, Dawei Wang, Ao Chen, Bin Jiang

Source: Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-27 (2024)

Subject Terms: Exosomes derived from umbilical cord mesenchymal stem cells, Complex perianal fistulas, Wound healing, HIF-1α, TGF-β/Smad signaling pathway, Medicine (General), R5-920, Biochemistry, QD415-436

File Description: electronic resource

Relation: https://doaj.org/toc/1757-6512

Access URL: https://doaj.org/article/1d343d611d4849419ad4f38b542e6fa7

Daphnetin may protect from SARS-CoV-2 infection by reducing ACE2

Authors: Qian-wen Yang, Chang-ling Yue, Meng Chen, Yun-yun Ling, Qi Dong, Ying-xin Zhou, Yin Cao, Yan-xia Ding, Xu Zhao, Hai Huang, Zhao-huan Zhang, Lei Hu, Xiao-hui Xu

Source: Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)

Subject Terms: Severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2), Angiotensin-converting enzyme 2 (ACE2), Daphnetin (DAP), Prevention, HIF-1α, JAK2, Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/c7187b2a0b654c8693e1a67f865032d9

HIF-1α mediates hypertension and vascular remodeling in sleep apnea via hippo–YAP pathway activation

Authors: Shoude Zhang, Yuan Zhao, Zhanwei Dong, Mao Jin, Ying Lu, Mina Xu, Hong Pan, Guojin Zhou, Mang Xiao

Source: Molecular Medicine, Vol 30, Iss 1, Pp 1-10 (2024)

Subject Terms: Sleep apnea syndrome, HIF-1α, Hippo, YAP, Vascular remodeling, Inflammation, Therapeutics. Pharmacology, RM1-950, Biochemistry, QD415-436

File Description: electronic resource

Relation: https://doaj.org/toc/1528-3658

Access URL: https://doaj.org/article/7741fd28664349c1ae61df5a7fed914f