Bone marrow stromal cells induce chromatin remodeling in multiple myeloma cells leading to transcriptional changes

Authors: Moritz Binder, Raphael E. Szalat, Srikanth Talluri, Mariateresa Fulciniti, Hervé Avet-Loiseau, Giovanni Parmigiani, Mehmet K. Samur, Nikhil C. Munshi

Source: Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/9ae3e3ccba2e4821b3f01ffba88946f8

Large T cell clones expressing immune checkpoints increase during multiple myeloma evolution and predict treatment resistance

Authors: Cirino Botta, Cristina Perez, Marta Larrayoz, Noemi Puig, Maria-Teresa Cedena, Rosalinda Termini, Ibai Goicoechea, Sara Rodriguez, Aintzane Zabaleta, Aitziber Lopez, Sarai Sarvide, Laura Blanco, Daniele M. Papetti, Marco S. Nobile, Daniela Besozzi, Massimo Gentile, Pierpaolo Correale, Sergio Siragusa, Albert Oriol, Maria Esther González-Garcia, Anna Sureda, Felipe de Arriba, Rafael Rios Tamayo, Jose-Maria Moraleda, Mercedes Gironella, Miguel T. Hernandez, Joan Bargay, Luis Palomera, Albert Pérez-Montaña, Hartmut Goldschmidt, Hervé Avet-Loiseau, Aldo Roccaro, Alberto Orfao, Joaquin Martinez-Lopez, Laura Rosiñol, Juan-José Lahuerta, Joan Blade, Maria-Victoria Mateos, Jesús F. San-Miguel, Jose-Angel Martinez Climent, Bruno Paiva, the Programa Para el Estudio de la Terapéutica en Hemopatías Malignas/Grupo Español de Mieloma (PETHEMA/GEM) cooperative group, the iMMunocell study group

Source: Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/2de8f8a904e64dd0bd9521c3f7eaa173

Prognostic impact of translocation t(14;16) in multiple myeloma according to the presence of additional genetic lesions

Authors: Anaïs Schavgoulidze, Aurore Perrot, Titouan Cazaubiel, Xavier Leleu, Lydia Montes, Caroline Jacquet, Karim Belhadj, Sabine Brechignac, Laurent Frenzel, Thomas Chalopin, Philippe Rey, Jean-Marc Schiano de Collela, Mamoun Dib, Denis Caillot, Margaret Macro, Jean Fontan, Laure Buisson, Luka Pavageau, Murielle Roussel, Salomon Manier, Mohamad Mohty, Ludovic Martinet, Hervé Avet-Loiseau, Jill Corre

Source: Blood Cancer Journal, Vol 13, Iss 1, Pp 1-3 (2023)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2044-5385

Access URL: https://doaj.org/article/014de08446e748988123889eb0f6ca30

Deneddylation of ribosomal proteins promotes synergy between MLN4924 and chemotherapy to elicit complete therapeutic responses

Authors: Arthur Aubry, Joel D. Pearson, Jason Charish, Tao Yu, Jeremy M. Sivak, Dimitris P. Xirodimas, Hervé Avet-Loiseau, Jill Corre, Philippe P. Monnier, Rod Bremner

Source: Cell Reports, Vol 43, Iss 2, Pp 113711- (2024)

Subject Terms: Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211124724000391; https://doaj.org/toc/2211-1247

Access URL: https://doaj.org/article/e123ac04ad4e41e196e403a93c6013ec

t(11;14) status is stable between diagnosis and relapse and concordant between detection methodologies based on fluorescence in situ hybridization and next-generation sequencing in patients with multiple myeloma

Authors: Hervé Avet-Loiseau, Raphaële Thiébaut-Millot, Xiaotong Li, Jeremy A. Ross, Carlos Hader

Source: Haematologica, Vol 109, Iss 6 (2023)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: https://haematologica.org/article/view/11354; https://doaj.org/toc/0390-6078; https://doaj.org/toc/1592-8721

Access URL: https://doaj.org/article/ee5224ce82da4f449b50e2bdf89f87da

Measurable Residual Disease Testing in Multiple Myeloma Routine Clinical Practice: A Modified Delphi Study

Authors: Karthik Ramasamy, Hervé Avet-Loiseau, Cecilie Hveding Blimark, Michel Delforge, Francesca Gay, Salomon Manier, Joaquín Martinez-Lopez, Maria Victoria Mateos, Mohamad Mohty, Niels W.C.J. van de Donk, Katja Weisel

Source: HemaSphere, Vol 7, Iss 9, p e942 (2023)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: http://journals.lww.com/10.1097/HS9.0000000000000942; https://doaj.org/toc/2572-9241

Access URL: https://doaj.org/article/f62092dd32894195b5a254c9595e4e6c

Deneddylation of ribosomal proteins promotes synergy between MLN4924 and chemotherapy to elicit complete therapeutic responses

Authors: Arthur Aubry, Joel D. Pearson, Jason Charish, Tao Yu, Jeremy M. Sivak, Dimitris P. Xirodimas, Hervé Avet-Loiseau, Jill Corre, Philippe P. Monnier, Rod Bremner

Source: Cell Reports, Vol 42, Iss 8, Pp 112925- (2023)

Subject Terms: CP: Cancer, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211124723009361; https://doaj.org/toc/2211-1247

Access URL: https://doaj.org/article/98133b06f2024ab69e0484aa57d6b411

Real-world study of the efficacy and safety of belantamab mafodotin (GSK2857916) in relapsed or refractory multiple myeloma based on data from the nominative ATU in France: the IFM 2020-04 study

Authors: Alexis Talbot, Arthur Bobin, Léa Tabone, Jérôme Lambert, Catherine Boccaccio, Cécile Deal, Marie-Odile Petillon, Olivier Allangba, Philippe Agape, Pierre Arnautou, Rakiba Belkhir, Sylvie Cailleres, Driss Chaoui, Marie-Lorraine Chrétien, Olivier Decaux, Samantha Schulmann, Laurent Frenzel, Lauris Gastaud, Antoine Huart, Cyrille Hulin, Lionel Karlin, Kamel Laribi, Ronan Le Calloch, Pascal Lenain, Margaret Macro, Salomon Manier, Lydia Montes, Stéphane Moreau, Philippe Moreau, Véronique Morel, James Norwood, Frédérique Orsini Piocelle, Aurore Perrot, Gian Matteo Pica, Philippe Rey, Anna Schmitt, Anne-Marie Stoppa, Mourad Tiab, Cyrille Touzeau, Valérie Vidal, Marguerite Vignon, Laure Vincent, Zoé Van De Wyngaert, Charles Zarnitsky, Naima Kerbouche, Prani Paka, Xavier Leleu, Bertrand Arnulf, Hervé Avet-Loiseau, IFM: Intergroupe Francophone du Myélome

Source: Haematologica, Vol 108, Iss 10 (2023)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: https://haematologica.org/article/view/11056; https://doaj.org/toc/0390-6078; https://doaj.org/toc/1592-8721

Access URL: https://doaj.org/article/b1c5d27182c748cbbd625be53da24488

The DNA methylation landscape of multiple myeloma shows extensive inter- and intrapatient heterogeneity that fuels transcriptomic variability

Authors: Jennifer Derrien, Catherine Guérin-Charbonnel, Victor Gaborit, Loïc Campion, Magali Devic, Elise Douillard, Nathalie Roi, Hervé Avet-Loiseau, Olivier Decaux, Thierry Facon, Jan-Philipp Mallm, Roland Eils, Nikhil C. Munshi, Philippe Moreau, Carl Herrmann, Florence Magrangeas, Stéphane Minvielle

Source: Genome Medicine, Vol 13, Iss 1, Pp 1-21 (2021)

Subject Terms: Multiple myeloma, Disordered DNA methylation, Epipolymorphism, Epiallele switching, Inter- and intrapatient heterogeneity, Transcriptomic variability, Medicine, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1756-994X

Access URL: https://doaj.org/article/4a911b1129d149468316660d33d6e2e4

Prognostic value of positron emission tomography/computed tomography in transplant-eligible newly diagnosed multiple myeloma patients from CASSIOPEIA: the CASSIOPET study

Authors: Françoise Kraeber-Bodéré, Sonja Zweegman, Aurore Perrot, Cyrille Hulin, Denis Caillot, Thierry Facon, Xavier Leleu, Karim Belhadj, Emmanuel Itti, Lionel Karlin, Clément Bailly, Mark-David Levin, Monique C. Minnema, Bastien Jamet, Caroline Bodet-Milin, Bart de Keizer, Marie C. Béné, Hervé Avet-Loiseau, Pieter Sonneveld, Lixia Pei, Fabio Rigat, Carla de Boer, Jessica Vermeulen, Tobias Kampfenkel, Jérôme Lambert, Philippe Moreau

Source: Haematologica, Vol 108, Iss 2 (2022)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: https://haematologica.org/article/view/10836; https://doaj.org/toc/0390-6078; https://doaj.org/toc/1592-8721

Access URL: https://doaj.org/article/3b889894f40047c1a3e16e3221ec5161

Genetically determined telomere length and multiple myeloma risk and outcome

Authors: Matteo Giaccherini, Angelica Macauda, Enrico Orciuolo, Marcin Rymko, Karolina Gruenpeter, Charles Dumontet, Malgorzata Raźny, Victor Moreno, Gabriele Buda, Katia Beider, Judit Varkonyi, Hervé Avet-Loiseau, Joaquín Martinez-Lopez, Herlander Marques, Marzena Watek, Maria Eugenia Sarasquete, Vibeke Andersen, Lionel Karlin, Anna Suska, Marcin Kruszewski, Niels Abildgaard, Marek Dudziński, Aleksandra Butrym, Arnold Nagler, Annette Juul Vangsted, Katalin Kadar, Tomczak Waldemar, Krzysztof Jamroziak, Svend Erik Hove Jacobsen, Lene Hyldahl Ebbesen, Michał Taszner, Grzegorz Mazur, Fabienne Lesueur, Matteo Pelosini, Ramon Garcia-Sanz, Artur Jurczyszyn, Delphine Demangel, Rui Manuel Reis, Elżbieta Iskierka-Jażdżewska, Miroslaw Markiewicz, Federica Gemignani, Edyta Subocz, Daria Zawirska, Agnieszka Druzd-Sitek, Anna Stępień, M. Henar Alonso, Juan Sainz, Federico Canzian, Daniele Campa

Source: Blood Cancer Journal, Vol 11, Iss 4, Pp 1-10 (2021)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2044-5385

Access URL: https://doaj.org/article/a30e9bbd7c0543db9834e87fd2531155

Daratumumab, bortezomib, and dexamethasone in relapsed or refractory multiple myeloma: subgroup analysis of CASTOR based on cytogenetic risk

Authors: Katja Weisel, Andrew Spencer, Suzanne Lentzsch, Hervé Avet-Loiseau, Tomer M. Mark, Ivan Spicka, Tamas Masszi, Birgitta Lauri, Mark-David Levin, Alberto Bosi, Vania Hungria, Michele Cavo, Je-Jung Lee, Ajay Nooka, Hang Quach, Markus Munder, Cindy Lee, Wolney Barreto, Paolo Corradini, Chang-Ki Min, Asher A. Chanan-Khan, Noemi Horvath, Marcelo Capra, Meral Beksac, Roberto Ovilla, Jae-Cheol Jo, Ho-Jin Shin, Pieter Sonneveld, Tineke Casneuf, Nikki DeAngelis, Himal Amin, Jon Ukropec, Rachel Kobos, Maria-Victoria Mateos

Source: Journal of Hematology & Oncology, Vol 13, Iss 1, Pp 1-11 (2020)

Subject Terms: Clinical trials, Multiple myeloma, Myeloma therapy, Diseases of the blood and blood-forming organs, RC633-647.5, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s13045-020-00948-5; https://doaj.org/toc/1756-8722

Access URL: https://doaj.org/article/f4bcd4b8584c4c2d8d002b323f628268

Genomic landscape and chronological reconstruction of driver events in multiple myeloma

Authors: Francesco Maura, Niccoló Bolli, Nicos Angelopoulos, Kevin J. Dawson, Daniel Leongamornlert, Inigo Martincorena, Thomas J. Mitchell, Anthony Fullam, Santiago Gonzalez, Raphael Szalat, Federico Abascal, Bernardo Rodriguez-Martin, Mehmet Kemal Samur, Dominik Glodzik, Marco Roncador, Mariateresa Fulciniti, Yu Tzu Tai, Stephane Minvielle, Florence Magrangeas, Philippe Moreau, Paolo Corradini, Kenneth C. Anderson, Jose M. C. Tubio, David C. Wedge, Moritz Gerstung, Hervé Avet-Loiseau, Nikhil Munshi, Peter J. Campbell

Source: Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/a38608a486ef471e8da57b4ab94d19b3

Cerebrospinal Fluid Penetrance of Daratumumab in Leptomeningeal Multiple Myeloma

Authors: Marina Zajec, Kristine A. Frerichs, Martijn M. van Duijn, Inger S. Nijhof, Claudia A.M. Stege, Hervé Avet-Loiseau, Theo M. Luider, Yolanda B. de Rijke, Joannes F.M. Jacobs, Niels W.C.J. van de Donk

Source: HemaSphere, Vol 4, Iss 4, p e413 (2020)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: http://journals.lww.com/10.1097/HS9.0000000000000413; https://doaj.org/toc/2572-9241

Access URL: https://doaj.org/article/c155433dffb4445b92089d717e228eab

Early relapse after autologous transplant for myeloma is associated with poor survival regardless of cytogenetic risk

Authors: Jill Corre, Lydia Montes, Elodie Martin, Aurore Perrot, Denis Caillot, Xavier Leleu, Karim Belhadj, Thierry Facon, Cyrille Hulin, Mohamad Mohty, Jean Fontan, Margaret Macro, Sabine Brechignac, Arnaud Jaccard, Anne-Marie Stoppa, Frederique Orsini-Piocelle, Didier Adiko, Laurent Voillat, Faiza Keddar, Marly Barry, Helene Demarquette, Marie-Noelle Certain, Isabelle Plantier, Murielle Roussel, Benjamin Hébraud, Thomas Filleron, Michel Attal, Hervé Avet-Loiseau

Source: Haematologica, Vol 105, Iss 9 (2020)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: https://haematologica.org/article/view/9866; https://doaj.org/toc/0390-6078; https://doaj.org/toc/1592-8721

Access URL: https://doaj.org/article/27c1ede544f04fbe9c4a550e1ed27435

Logic programming reveals alteration of key transcription factors in multiple myeloma

Authors: Bertrand Miannay, Stéphane Minvielle, Olivier Roux, Pierre Drouin, Hervé Avet-Loiseau, Catherine Guérin-Charbonnel, Wilfried Gouraud, Michel Attal, Thierry Facon, Nikhil C Munshi, Philippe Moreau, Loïc Campion, Florence Magrangeas, Carito Guziolowski

Source: Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/a8448570cfee4cc69771d5a8924d77e8

Functional Comparison between Healthy and Multiple Myeloma Adipose Stromal Cells

Authors: Nicolas Espagnolle, Benjamin Hebraud, Jean-Gérard Descamps, Mélanie Gadelorge, Marie-Véronique Joubert, Laura Do Souto Ferreira, Murielle Roussel, Anne Huynh, Luc Sensébé, Louis Casteilla, Michel Attal, Hervé Avet-Loiseau, Frederic Deschaseaux, Philippe Bourin, Jill Corre

Source: Stem Cells International, Vol 2020 (2020)

Subject Terms: Internal medicine, RC31-1245

File Description: electronic resource

Relation: https://doaj.org/toc/1687-966X; https://doaj.org/toc/1687-9678

Access URL: https://doaj.org/article/b236d90616004262ad97400f3a2e8850

Daratumumab plus bortezomib and dexamethasone versus bortezomib and dexamethasone in relapsed or refractory multiple myeloma: updated analysis of CASTOR

Authors: Andrew Spencer, Suzanne Lentzsch, Katja Weisel, Hervé Avet-Loiseau, Tomer M. Mark, Ivan Spicka, Tamas Masszi, Birgitta Lauri, Mark-David Levin, Alberto Bosi, Vania Hungria, Michele Cavo, Je-Jung Lee, Ajay K. Nooka, Hang Quach, Cindy Lee, Wolney Barreto, Paolo Corradini, Chang-Ki Min, Emma C. Scott, Asher A. Chanan-Khan, Noemi Horvath, Marcelo Capra, Meral Beksac, Roberto Ovilla, Jae-Cheol Jo, Ho-Jin Shin, Pieter Sonneveld, David Soong, Tineke Casneuf, Christopher Chiu, Himal Amin, Ming Qi, Piruntha Thiyagarajah, A. Kate Sasser, Jordan M. Schecter, Maria-Victoria Mateos

Source: Haematologica, Vol 103, Iss 12 (2018)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: https://haematologica.org/article/view/8704; https://doaj.org/toc/0390-6078; https://doaj.org/toc/1592-8721

Access URL: https://doaj.org/article/a34eb4051074415eaed565a3bdec8188

Daratumumab plus lenalidomide and dexamethasone versus lenalidomide and dexamethasone in relapsed or refractory multiple myeloma: updated analysis of POLLUX

Authors: Meletios A. Dimopoulos, Jesus San-Miguel, Andrew Belch, Darrell White, Lotfi Benboubker, Gordon Cook, Merav Leiba, James Morton, P. Joy Ho, Kihyun Kim, Naoki Takezako, Philippe Moreau, Jonathan L. Kaufman, Heather J. Sutherland, Marc Lalancette, Hila Magen, Shinsuke Iida, Jin Seok Kim, H. Miles Prince, Tara Cochrane, Albert Oriol, Nizar J. Bahlis, Ajai Chari, Lisa O’Rourke, Kaida Wu, Jordan M. Schecter, Tineke Casneuf, Christopher Chiu, David Soong, A. Kate Sasser, Nushmia Z. Khokhar, Hervé Avet-Loiseau, Saad Z. Usmani

Source: Haematologica, Vol 103, Iss 12 (2018)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: https://haematologica.org/article/view/8705; https://doaj.org/toc/0390-6078; https://doaj.org/toc/1592-8721

Access URL: https://doaj.org/article/34bc86c721f547c0b175882c23aa9838

Phase II study of bendamustine, bortezomib and dexamethasone as second-line treatment for elderly patients with multiple myeloma: the Intergroupe Francophone du Myelome 2009-01 trial

Authors: Philippe Rodon, Cyrille Hulin, Brigitte Pegourie, Mourad Tiab, Bruno Anglaret, Lotfi Benboubker, Henry Jardel, Olivier Decaux, Brigitte Kolb, Murielle Roussel, Laurent Garderet, Xavier Leleu, Olivier Fitoussi, Carine Chaleteix, Philippe Casassus, Pascal Lenain, Bruno Royer, Anne Banos, Riad Benramdane, Pascale Cony-Makhoul, Mamoun Dib, Jean Fontan, Anne-Marie Stoppa, Catherine Traullé, Jean-Pierre Vilque, Marie-Odile Pétillon, Claire Mathiot, Thomas Dejoie, Hervé Avet-Loiseau, Philippe Moreau

Source: Haematologica, Vol 100, Iss 2 (2015)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: https://haematologica.org/article/view/7293; https://doaj.org/toc/0390-6078; https://doaj.org/toc/1592-8721

Access URL: https://doaj.org/article/3d93e92c9c8d4e3e8d7660d9cc31d254