Let’s get in sync: current standing and future of AI-based detection of patient-ventilator asynchrony

Authors: Thijs P. Rietveld, Björn J. P. van der Ster, Abraham Schoe, Henrik Endeman, Anton Balakirev, Daria Kozlova, Diederik A. M. P. J. Gommers, Annemijn H. Jonkman

Source: Intensive Care Medicine Experimental, Vol 13, Iss 1, Pp 1-14 (2025)

Subject Terms: Patient-ventilator asynchrony, Mechanical ventilation, ICU, Artificial intelligence, Rule-based algorithms, Machine learning, Medical emergencies. Critical care. Intensive care. First aid, RC86-88.9

File Description: electronic resource

Relation: https://doaj.org/toc/2197-425X

Access URL: https://doaj.org/article/19b4b0ffa91a4245944a841a14f1f8de

The prognostic role of cardiac and inflammatory biomarkers in extubation failure in patients with COVID-19 acute respiratory distress syndrome

Authors: Carline N. L. Groenland, Adinde H. Siemers, Eric A. Dubois, Diederik Gommers, Leo Heunks, Evert-Jan Wils, Vivan J. M. Baggen, Henrik Endeman

Source: Annals of Intensive Care, Vol 15, Iss 1, Pp 1-10 (2025)

Subject Terms: Extubation failure, Mechanical ventilation, High-sensitivity Troponin T, N-Terminal pro-B-Type natriuretic peptide, Interleukin-6, Procalcitonin, Medical emergencies. Critical care. Intensive care. First aid, RC86-88.9

File Description: electronic resource

Relation: https://doaj.org/toc/2110-5820

Access URL: https://doaj.org/article/859a495c57184a7fa8b69d471fd9239b

Exploring lymphocyte subsets in COVID-19 patients: insights from a tertiary academic medical center with a high proportion of patients on immunosuppression

Authors: Katrijn Daenen, Samantha van Hooijdonk, Kirby Tong-Minh, Willem A. Dik, Petrus M. van Hagen, Jilske A. Huijben, Diederik Gommers, Eric C. M. van Gorp, Henrik Endeman, Virgil A. S. H. Dalm

Source: Frontiers in Immunology, Vol 15 (2024)

Subject Terms: COVID-19, lymphocyte subsets, infectious diseases, severity, prediction, immunosuppression, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2024.1436637/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/adac566317c14b7fb89fe4f9047828f3

Electrical Impedance Tomography as a monitoring tool during weaning from mechanical ventilation: an observational study during the spontaneous breathing trial

Authors: Jantine J. Wisse, Tom G. Goos, Annemijn H. Jonkman, Peter Somhorst, Irwin K. M. Reiss, Henrik Endeman, Diederik Gommers

Source: Respiratory Research, Vol 25, Iss 1, Pp 1-10 (2024)

Subject Terms: Electrical Impedance Tomography, EIT, Spontaneous breathing trial, Weaning, Diseases of the respiratory system, RC705-779

File Description: electronic resource

Relation: https://doaj.org/toc/1465-993X

Access URL: https://doaj.org/article/efffc403efd34042afc7f4c54256c4d7

Prognostic significance of muscle fasciculations in critically Ill COVID-19 patients under mechanical ventilation

Authors: Jeroen Molinger, John Whittle, Susie Cha, David MacLeod, Marat Fudim, Luis Ulloa, Christina Barkauskas, Zachary Healy, Krista L. Haines, Rajan T. Gupta, Henrik Endeman, Mathieu van der Jagt, Diederik Gommers, Jan Bakker, Paul E. Wischmeyer

Source: Frontiers in Anesthesiology, Vol 3 (2024)

Subject Terms: ICU-AW, SARS-coV, muscle fasciculations, muscle wasting, muscle ultrasound, Anesthesiology, RD78.3-87.3

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fanes.2024.1440038/full; https://doaj.org/toc/2813-480X

Access URL: https://doaj.org/article/c1678bfd796f45509c3428e33d0f7e17

A novel ultrasound approach in assessing IMAT in critically ill patients

Authors: Jeroen Molinger, John Whittle, Henrik Endeman, David MacLeod, Rajan Gupta, Marat Fudim, Krista L. Haines, Christina Barkauskas, Zachary Healy, Paul Wischmeyer, Jan Bakker

Source: Frontiers in Anesthesiology, Vol 3 (2024)

Subject Terms: IMAT intermuscular adipose tissue, muscle ultrasound, ICU acquired muscle weakness, muscle wasting, muscle weakneess, critical illness, Anesthesiology, RD78.3-87.3

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fanes.2024.1458633/full; https://doaj.org/toc/2813-480X

Access URL: https://doaj.org/article/07396a54023c4250bf13e957a840efce

Flow-controlled ventilation decreases mechanical power in postoperative ICU patients

Authors: Julien P. Van Oosten, Juliette E. Francovich, Peter Somhorst, Philip van der Zee, Henrik Endeman, Diederik A. M. P. J. Gommers, Annemijn H. Jonkman

Source: Intensive Care Medicine Experimental, Vol 12, Iss 1, Pp 1-11 (2024)

Subject Terms: Flow-controlled ventilation, FCV, ICU, Electrical impedance tomography, Mechanical power, Medical emergencies. Critical care. Intensive care. First aid, RC86-88.9

File Description: electronic resource

Relation: https://doaj.org/toc/2197-425X

Access URL: https://doaj.org/article/d74c9172f7f84ef0af2903774de8e6a0

Diaphragm excursions as proxy for tidal volume during spontaneous breathing in invasively ventilated ICU patients

Authors: Matthijs L. Janssen, Annemijn H. Jonkman, Myrte Wennen, Evert-Jan Wils, Henrik Endeman, Leo Heunks

Source: Intensive Care Medicine Experimental, Vol 11, Iss 1, Pp 1-7 (2023)

Subject Terms: Respiratory failure, Diaphragm excursion, Tidal volume, P-SILI, Non-invasive respiratory support, High-flow nasal oxygen, Medical emergencies. Critical care. Intensive care. First aid, RC86-88.9

File Description: electronic resource

Relation: https://doaj.org/toc/2197-425X

Access URL: https://doaj.org/article/7f8029721da64991a59de07402a02fbe

The diagnostic accuracy of lung ultrasound to determine PiCCO-derived extravascular lung water in invasively ventilated patients with COVID-19 ARDS

Authors: Leila N. Atmowihardjo, Job R. Schippers, Mark E. Haaksma, Marry R. Smit, Harm J. Bogaard, Leo Heunks, Nicole P. Juffermans, Marcus J. Schultz, Henrik Endeman, Patricia van Velzen, Pieter R. Tuinman, Jurjan Aman, Lieuwe D. J. Bos

Source: The Ultrasound Journal, Vol 15, Iss 1, Pp 1-11 (2023)

Subject Terms: Ultrasonography, Thermodilution, Extravascular lung water, Pulmonary edema, COVID-19, Respiratory distress syndrome, Medical physics. Medical radiology. Nuclear medicine, R895-920

File Description: electronic resource

Relation: https://doaj.org/toc/2524-8987

Access URL: https://doaj.org/article/d474e83ef80d45cc9a8302595f1e262f

Efficacy and safety of intravenous imatinib in COVID-19 ARDS: a randomized, double-blind, placebo-controlled clinical trial

Authors: Leila N. Atmowihardjo, Job R. Schippers, Erik Duijvelaar, Imke H. Bartelink, Pierre M. Bet, Noortje E. L. Swart, Nienke van Rein, Keith Purdy, David Cavalla, Andrew McElroy, Sarah Fritchley, Anton Vonk Noordegraaf, Henrik Endeman, Patricia van Velzen, Matty Koopmans, Harm Jan Bogaard, Leo Heunks, Nicole Juffermans, Marcus J. Schultz, Pieter R. Tuinman, Lieuwe D. J. Bos, Jurjan Aman

Source: Critical Care, Vol 27, Iss 1, Pp 1-13 (2023)

Subject Terms: COVID-19, ARDS, Imatinib, Vascular permeability, Endothelial barrier dysfunction, Pulmonary edema, Medical emergencies. Critical care. Intensive care. First aid, RC86-88.9

File Description: electronic resource

Relation: https://doaj.org/toc/1364-8535

Access URL: https://doaj.org/article/9b66fd0c759d40f6b53c6782c1837294

Effect of lung ultrasound-guided fluid deresuscitation on duration of ventilation in intensive care unit patients (CONFIDENCE): protocol for a multicentre randomised controlled trial

Authors: Siebe G. Blok, Amne Mousa, Michelle G. Brouwer, Harm-Jan de Grooth, Ary Serpa Neto, Michiel J. Blans, Sylvia den Boer, Tom Dormans, Henrik Endeman, Timo Roeleveld, Harm Scholten, Eline R. van Slobbe-Bijlsma, Erik Scholten, Hugo Touw, Fleur Stefanie L. I. M. van der Ven, Evert-Jan Wils, David J. van Westerloo, Leo M. A. Heunks, Marcus J. Schultz, Frederique Paulus, Pieter R. Tuinman

Source: Trials, Vol 24, Iss 1, Pp 1-11 (2023)

Subject Terms: Pulmonary oedema, Deresuscitation, Invasive ventilation, Critical care, Lung ultrasound, Randomised controlled trial, Medicine (General), R5-920

File Description: electronic resource

Relation: https://doaj.org/toc/1745-6215

Access URL: https://doaj.org/article/0c4fa15535a041d7b236f435619001f8

Prognostic models for outcome prediction following in-hospital cardiac arrest using pre-arrest factors: a systematic review, meta-analysis and critical appraisal

Authors: Casey Grandbois van Ravenhorst, Marc Schluep, Henrik Endeman, Robert-Jan Stolker, Sanne Elisabeth Hoeks

Source: Critical Care, Vol 27, Iss 1, Pp 1-20 (2023)

Subject Terms: In-hospital cardiac arrest, Cardiopulmonary resuscitation, Clinical outcome, Prognostic model, Medical emergencies. Critical care. Intensive care. First aid, RC86-88.9

File Description: electronic resource

Relation: https://doaj.org/toc/1364-8535

Access URL: https://doaj.org/article/cde41825f06e44f191f54b745068663d

Microcirculatory alterations in critically ill COVID-19 patients analyzed using artificial intelligence

Authors: Matthias Peter Hilty, Emanuele Favaron, Pedro David Wendel Garcia, Yavuz Ahiska, Zuhre Uz, Sakir Akin, Moritz Flick, Sesmu Arbous, Daniel A. Hofmaenner, Bernd Saugel, Henrik Endeman, Reto Andreas Schuepbach, Can Ince

Source: Critical Care, Vol 26, Iss 1, Pp 1-11 (2022)

Subject Terms: Microcirculation, COVID-19, Deep learning, Neuronal network, Artificial intelligence, Medical emergencies. Critical care. Intensive care. First aid, RC86-88.9

File Description: electronic resource

Relation: https://doaj.org/toc/1364-8535

Access URL: https://doaj.org/article/ad35dfa3719247249a2e1924bde36922

Antibodies against angiotensin II receptor type 1 and endothelin A receptor are increased in COVID-19 patients

Authors: Jelle R. Miedema, Matthijs L. Janssen, Jan von der Thüsen, Henrik Endeman, Anton W. Langerak, Merel E. Hellemons, Els van Nood, Bas W. A. Peeters, Sara J. Baart, Marco W. J. Schreurs

Source: Frontiers in Immunology, Vol 14 (2023)

Subject Terms: COVID-19, endothelin receptor type A antibody, angiotensin II receptor type 1 antibody, antinuclear antibody (ANA), autoimmunity, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2023.1204433/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/5501f589f5ac42268f103cfaa3443a8c

PEEP-FiO2 table versus EIT to titrate PEEP in mechanically ventilated patients with COVID-19-related ARDS

Authors: Peter Somhorst, Philip van der Zee, Henrik Endeman, Diederik Gommers

Source: Critical Care, Vol 26, Iss 1, Pp 1-10 (2022)

Subject Terms: COVID-19, Acute respiratory distress syndrome, Mechanical ventilation, Positive end-expiratory pressure, Electrical impedance tomography, Medical emergencies. Critical care. Intensive care. First aid, RC86-88.9

File Description: electronic resource

Relation: https://doaj.org/toc/1364-8535

Access URL: https://doaj.org/article/0ce5000c05ba4581b02e7ea72c90b704

Development and validation of an early warning model for hospitalized COVID-19 patients: a multi-center retrospective cohort study

Authors: Jim M. Smit, Jesse H. Krijthe, Andrei N. Tintu, Henrik Endeman, Jeroen Ludikhuize, Michel E. van Genderen, Shermarke Hassan, Rachida El Moussaoui, Peter E. Westerweel, Robbert J. Goekoop, Geeke Waverijn, Tim Verheijen, Jan G. den Hollander, Mark G. J. de Boer, Diederik A. M. P. J. Gommers, Robin van der Vlies, Mark Schellings, Regina A. Carels, Cees van Nieuwkoop, Sesmu M. Arbous, Jasper van Bommel, Rachel Knevel, Yolanda B. de Rijke, Marcel J. T. Reinders

Source: Intensive Care Medicine Experimental, Vol 10, Iss 1, Pp 1-18 (2022)

Subject Terms: COVID-19, Early warning score, Intensive care, Machine learning, Artificial intelligence, Medical prediction model, Medical emergencies. Critical care. Intensive care. First aid, RC86-88.9

File Description: electronic resource

Relation: https://doaj.org/toc/2197-425X

Access URL: https://doaj.org/article/adac0ffa1c414d52b8915466386d496a

Barriers and facilitators for therapeutic drug monitoring of beta-lactams and ciprofloxacin in the ICU: a nationwide cross-sectional study

Authors: Tim M. J. Ewoldt, Alan Abdulla, Puck van den Broek, Nicole Hunfeld, Soma Bahmany, Anouk E. Muller, Diederik Gommers, Suzanne Polinder, Henrik Endeman, Inge Spronk, Birgit C. P. Koch

Source: BMC Infectious Diseases, Vol 22, Iss 1, Pp 1-9 (2022)

Subject Terms: Survey, Beta-lactam antibiotics, Ciprofloxacin, Therapeutic drug monitoring, Intensive care, Barriers, Infectious and parasitic diseases, RC109-216

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2334

Access URL: https://doaj.org/article/ddd085123370440f945e9846c156ba88

Exploring the Impact of Model-Informed Precision Dosing on Procalcitonin Concentrations in Critically Ill Patients: A Secondary Analysis of the DOLPHIN Trial

Authors: Sarah Dräger, Tim M. J. Ewoldt, Alan Abdulla, Wim J. R. Rietdijk, Nelianne Verkaik, Christian Ramakers, Evelien de Jong, Michael Osthoff, Birgit C. P. Koch, Henrik Endeman

Source: Pharmaceutics, Vol 16, Iss 2, p 270 (2024)

Subject Terms: model-informed precision dosing, procalcitonin, inflammation, biomarker, antibiotics, critically ill, Pharmacy and materia medica, RS1-441

File Description: electronic resource

Relation: https://www.mdpi.com/1999-4923/16/2/270; https://doaj.org/toc/1999-4923

Access URL: https://doaj.org/article/20dfc43e81b74cc2904b0c650262e4d7

Optimal Dosing and Timing of High-Dose Corticosteroid Therapy in Hospitalized Patients With COVID-19: Study Protocol for a Retrospective Observational Multicenter Study (SELECT)

Authors: Katrijn Daenen, Jilske A Huijben, Anders Boyd, Lieuwe D J Bos, Sara C M Stoof, Hugo van Willigen, Diederik A M P J Gommers, Hazra S Moeniralam, Corstiaan A den Uil, Nicole P Juffermans, Merijn Kant, Abraham J Valkenburg, Janesh Pillay, David M P van Meenen, Frederique Paulus, Marcus J Schultz, Virgil A S H Dalm, Eric C M van Gorp, Janke Schinkel, Henrik Endeman

Source: JMIR Research Protocols, Vol 12, p e48183 (2023)

Subject Terms: Medicine, Computer applications to medicine. Medical informatics, R858-859.7

File Description: electronic resource

Relation: https://www.researchprotocols.org/2023/1/e48183; https://doaj.org/toc/1929-0748

Access URL: https://doaj.org/article/1f915a3b9dca45afacf50674f5cca22b

High procalcitonin levels associated with increased intensive care unit admission and mortality in patients with a COVID-19 infection in the emergency department

Authors: Kirby Tong-Minh, Yuri van der Does, Susanna Engelen, Evelien de Jong, Christian Ramakers, Diederik Gommers, Eric van Gorp, Henrik Endeman

Source: BMC Infectious Diseases, Vol 22, Iss 1, Pp 1-9 (2022)

Subject Terms: COVID-19, Biomarkers, Emergency department, Procalcitonin, Infectious and parasitic diseases, RC109-216

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2334

Access URL: https://doaj.org/article/a4733811491549508cce28b64ed6e73a