Metabolic regulation of type I interferon production.

Authors: O'Carroll, Shane M.¹ (AUTHOR) shocarro@tcd.ie, Henkel, Fiona D. R.^1,2 (AUTHOR), O'Neill, Luke A. J.¹ (AUTHOR)

Source: Immunological Reviews. May2024, Vol. 323 Issue 1, p276-287. 12p.

Subject Terms: *TYPE I interferons, *LIPID metabolism, *CELL physiology, *INTERFERONS, *TRICARBOXYLIC acids

A helminth enzyme subverts macrophage-mediated immunity by epigenetic targeting of prostaglandin synthesis.

Authors: Bohnacker, Sina, Henkel, Fiona D. R., Hartung, Franziska, Geerlof, Arie, Riemer, Sandra, Prodjinotho, Ulrich F., Salah, Eya Ben, Mourão, André Santos Dias, Bohn, Stefan, Teder, Tarvi, Thomas, Dominique, Gurke, Robert, Boeckel, Christiane, Ud-Dean, Minhaz, König, Ann-Christine, Quaranta, Alessandro, Alessandrini, Francesca, Lechner, Antonie, Spitzlberger, Benedikt, Kabat, Agnieszka M.

Source: Science Immunology; 2024, Vol. 9 Issue 102, p1-24, 24p

Subject Terms: GLUTAMATE dehydrogenase, T helper cells, INDOLEAMINE 2,3-dioxygenase, INTESTINAL parasites, HISTONE acetylation

Extracellular vesicle miRNAs drive aberrant macrophage responses in NSAID‐exacerbated respiratory disease.

Authors: Hartung, Franziska, Haimerl, Pascal, Schindela, Sonja, Mussack, Veronika, Kirchner, Benedikt, Henkel, Fiona D. R., Bernhardt, Ulrike, Zissler, Ulrich M., Santarella‐Mellwig, Rachel, Pfaffl, Michael, Schmidt‐Weber, Carsten B., Chaker, Adam M., Esser‐von Bieren, Julia

Source: Allergy; Jul2024, Vol. 79 Issue 7, p1893-1907, 15p

Subject Terms: EXTRACELLULAR vesicles, RESPIRATORY diseases, MICRORNA, MACROPHAGE activation, NASAL tumors, MACROPHAGES

House dust mite drives proinflammatory eicosanoid reprogramming and macrophage effector functions

Authors: Henkel, Fiona D. R., Friedl, Antonie, Haid, Mark, Thomas, Dominique, Bouchery, Tiffany, Haimerl, Pascal, Reyes Jiménez, Marta, Alessandrini, Francesca, Schmidt‐Weber, Carsten B., Harris, Nicola L., Adamski, Jerzy, Esser‐von Bieren, Julia

Source: Allergy. 74(6):1090-1101

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100083925498.0x000001&indx=1&recIds=ETOCvdc_100083925498.0x000001

Not just "leuko" after all: Epithelial leukotriene production in type 2 immunity.

Authors: Henkel, Fiona D. R., Bieren, Julia Esser-von

Source: Science Immunology; 2022, Vol. 7 Issue 67, p1-3, 3p

Subject Terms: NEMATODE infections, IMMUNITY, LEUKOTRIENES, TRP channels, OXYGENASES, LIQUID chromatography-mass spectrometry