The oncogene AAMDC links PI3K-AKT-mTOR signaling with metabolic reprograming in estrogen receptor-positive breast cancer

Authors: Emily Golden, Rabab Rashwan, Eleanor A. Woodward, Agustin Sgro, Edina Wang, Anabel Sorolla, Charlene Waryah, Wan Jun Tie, Elisabet Cuyàs, Magdalena Ratajska, Iwona Kardaś, Piotr Kozlowski, Elizabeth K. M. Johnstone, Heng B. See, Ciara Duffy, Jeremy Parry, Kim A. Lagerborg, Piotr Czapiewski, Javier A. Menendez, Adam Gorczyński, Bartosz Wasag, Kevin D. G. Pfleger, Christina Curtis, Bum-Kyu Lee, Jonghwan Kim, Joseph Cursons, Nathan J. Pavlos, Wojciech Biernat, Mohit Jain, Andrew J. Woo, Andrew Redfern, Pilar Blancafort

Source: Nature Communications, Vol 12, Iss 1, Pp 1-22 (2021)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/7a78efc95f94434186efe33c5a90c19a

Novel Pharmacology Following Heteromerization of the Angiotensin II Type 2 Receptor and the Bradykinin Type 2 Receptor

Authors: Elizabeth K. M. Johnstone, Mohammed Akli Ayoub, Rebecca J. Hertzman, Heng B. See, Rekhati S. Abhayawardana, Ruth M. Seeber, Kevin D. G. Pfleger

Source: Frontiers in Endocrinology, Vol 13 (2022)

Subject Terms: angiotensin receptor, bradykinin receptor, GPCR, BRET, receptor-HIT, heteromer, Diseases of the endocrine glands. Clinical endocrinology, RC648-665

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fendo.2022.848816/full; https://doaj.org/toc/1664-2392

Access URL: https://doaj.org/article/05b7a90cfa2845508b41819310d3747e

Using nanoBRET and CRISPR/Cas9 to monitor proximity to a genome-edited protein in real-time

Authors: Carl W. White, Hannah K. Vanyai, Heng B. See, Elizabeth K. M. Johnstone, Kevin D. G. Pfleger

Source: Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/7b3fcf6037e049f69f6a0bb8d24be1b0

Application of G Protein-Coupled Receptor-Heteromer Identification Technology to Monitor β-Arrestin Recruitment to G Protein-Coupled Receptor Heteromers.

Authors: Heng B. See, Ruth M. Seeber, Martina Kocan, Karin A. Eidne, Kevin D.G. Pfleger

Source: Assay & Drug Development Technologies; Feb2011, Vol. 9 Issue 1, p21-30, 10p

Subject Terms: G proteins, PATHOLOGICAL physiology, PHARMACOLOGY, MONOMERS, BIOLUMINESCENCE, RESONANCE, CHEMOKINES

Functional interaction between angiotensin II receptor type 1 and chemokine (C-C motif) receptor 2 with implications for chronic kidney disease.

Authors: Mohammed Akli Ayoub, Yuan Zhang, Robyn S Kelly, Heng B See, Elizabeth K M Johnstone, Elizabeth A McCall, James H Williams, Darren J Kelly, Kevin D G Pfleger

Source: PLoS ONE, Vol 10, Iss 3, p e0119803 (2015)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC4373786?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/825dcccc2ee44c6ca84f5db253560016

Profiling epidermal growth factor receptor and heregulin receptor 3 heteromerization using receptor tyrosine kinase heteromer investigation technology.

Authors: Mohammed Akli Ayoub, Heng B See, Ruth M Seeber, Stephen P Armstrong, Kevin D G Pfleger

Source: PLoS ONE, Vol 8, Iss 5, p e64672 (2013)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3659105?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/d870170f9b334f9a81b05246836f9afe