Myeloperoxidase-ANCA IgG induces different forms of small vessel vasculitis based on type of synergistic immune stimuli

Authors: Hu, Peiqi, Xiao, Hong, Alba, Marco A., Atkins, Hannah M., Gou, Shenju, Hu, Yanglin, Gomez, John C., Jania, Corey M., Martin, Jessica R., Morrison, Thomas E., Tilley, Stephen L., Heise, Mark T., Doerschuk, Claire M., Falk, Ronald J., Jennette, J. Charles

Source: In Kidney International November 2024 106(5):870-886

Genetic loci regulate Sarbecovirus pathogenesis: A comparison across mice and humans

Authors: Schäfer, Alexandra, Gralinski, Lisa E., Leist, Sarah R., Hampton, Brea K., Mooney, Michael A., Jensen, Kara L., Graham, Rachel L., Agnihothram, Sudhakar, Jeng, Sophia, Chamberlin, Steven, Bell, Timothy A., Scobey, D. Trevor, Linnertz, Colton L., VanBlargan, Laura A., Thackray, Larissa B., Hock, Pablo, Miller, Darla R., Shaw, Ginger D., Diamond, Michael S., de Villena, Fernando Pardo Manuel, McWeeney, Shannon K., Heise, Mark T., Menachery, Vineet D., Ferris, Martin T., Baric, Ralph S.

Source: In Virus Research June 2024 344

The RNA helicase DDX39A binds a conserved structure in chikungunya virus RNA to control infection

Authors: Tapescu, Iulia, Taschuk, Frances, Pokharel, Swechha M., Zginnyk, Oleksandr, Ferretti, Max, Bailer, Peter F., Whig, Kanupryia, Madden, Emily A., Heise, Mark T., Schultz, David C., Cherry, Sara

Source: In Molecular Cell 16 November 2023 83(22):4174-4189

Fc-mediated pan-sarbecovirus protection after alphavirus vector vaccination

Authors: Adams, Lily E., Leist, Sarah R., Dinnon, Kenneth H., III, West, Ande, Gully, Kendra L., Anderson, Elizabeth J., Loome, Jennifer F., Madden, Emily A., Powers, John M., Schäfer, Alexandra, Sarkar, Sanjay, Castillo, Izabella N., Maron, Jenny S., McNamara, Ryan P., Bertera, Harry L., Zweigart, Mark R., Higgins, Jaclyn S., Hampton, Brea K., Premkumar, Lakshmanane, Alter, Galit, Montgomery, Stephanie A., Baxter, Victoria K., Heise, Mark T., Baric, Ralph S.

Source: In Cell Reports 25 April 2023 42(4)

An epithelial-immune circuit amplifies inflammasome and IL-6 responses to SARS-CoV-2

Authors: Barnett, Katherine C., Xie, Yuying, Asakura, Takanori, Song, Dingka, Liang, Kaixin, Taft-Benz, Sharon A., Guo, Haitao, Yang, Shuangshuang, Okuda, Kenichi, Gilmore, Rodney C., Loome, Jennifer F., Oguin III, Thomas H., Sempowski, Gregory D., Randell, Scott H., Heise, Mark T., Lei, Yu Leo, Boucher, Richard C., Ting, Jenny P.-Y.

Source: In Cell Host & Microbe 8 February 2023 31(2):243-259

Development of a virulent O'nyong'nyong challenge model to determine heterologous protection mediated by a hydrogen peroxide-inactivated chikungunya virus vaccine.

Authors: Weber, Whitney C., Streblow, Zachary J., Andoh, Takeshi F., Denton, Michael, Raué, Hans-Peter, Amanna, Ian J., Slifka, Dawn K., Kreklywich, Craig N., Arduino, Irene, Sulgey, Gauthami, Streblow, Magdalene M., Heise, Mark T., Slifka, Mark K., Streblow, Daniel N.

Source: PLoS Neglected Tropical Diseases; 3/17/2025, Vol. 19 Issue 3, p1-22, 22p

Vaccine formulations in clinical development for the prevention of severe acute respiratory syndrome coronavirus 2 infection

Authors: Batty, Cole J., Heise, Mark T., Bachelder, Eric M., Ainslie, Kristy M.

Source: In Advanced Drug Delivery Reviews February 2021 169:168-189

4‑Substituted-2-Thiazole Amides as Viral Replication Inhibitors of Alphaviruses.

Authors: Garzan, Atefeh, Ahmed, S. Kaleem, Haese, Nicole N., Sulgey, Gauthami, Medica, Samuel, Smith, Jessica L., Zhang, Sixue, Ahmad, Fahim, Karyakarte, Shuklendu, Rasmussen, Lynn, DeFilippis, Victor, Tekwani, Babu, Bostwick, Robert, Suto, Mark J., Hirsch, Alec J., Morrison, Thomas E., Heise, Mark T., Augelli-Szafran, Corinne E., Streblow, Daniel N., Pathak, Ashish K.

Source: Journal of Medicinal Chemistry; 12/12/2024, Vol. 67 Issue 23, p20858-20878, 21p

Complex Genetic Architecture Underlies Regulation of Influenza-A-Virus-Specific Antibody Responses in the Collaborative Cross

Authors: Noll, Kelsey E., Whitmore, Alan C., West, Ande, McCarthy, Mary K., Morrison, Clayton R., Plante, Kenneth S., Hampton, Brea K., Kollmus, Heike, Pilzner, Carolin, Leist, Sarah R., Gralinski, Lisa E., Menachery, Vineet D., Schäfer, Alexandra, Miller, Darla, Shaw, Ginger, Mooney, Michael, McWeeney, Shannon, Pardo-Manuel de Villena, Fernando, Schughart, Klaus, Morrison, Thomas E., Baric, Ralph S., Ferris, Martin T., Heise, Mark T.

Source: In Cell Reports 28 April 2020 31(4)

The Collaborative Cross: A Systems Genetics Resource for Studying Host-Pathogen Interactions

Authors: Noll, Kelsey E., Ferris, Martin T., Heise, Mark T.

Source: In Cell Host & Microbe 10 April 2019 25(4):484-498

Structure Activity of β‑Amidomethyl Vinyl Sulfones as Covalent Inhibitors of Chikungunya nsP2 Cysteine Protease with Antialphavirus Activity.

Authors: Ghoshal, Anirban, Asressu, Kesatebrhan Haile, Hossain, Mohammad Anwar, Brown, Peter J., Nandakumar, Meganathan, Vala, Anand, Merten, Eric M., Sears, John D., Law, Isabella, Burdick, Jane E., Morales, Noah L., Perveen, Sumera, Pearce, Kenneth H., Popov, Konstantin I., Moorman, Nathaniel J., Heise, Mark T., Willson, Timothy M.

Source: Journal of Medicinal Chemistry; 9/26/2024, Vol. 67 Issue 18, p16505-16532, 28p

Chikungunya Virus RNA Secondary Structures Impact Defective Viral Genome Production.

Authors: Levi, Laura I., Madden, Emily A., Boussier, Jeremy, Erazo, Diana, Sanders, Wes, Vallet, Thomas, Bernhauerova, Veronika, Moorman, Nathaniel J., Heise, Mark T., Vignuzzi, Marco

Source: Microorganisms; Sep2024, Vol. 12 Issue 9, p1794, 15p

Subject Terms: CHIKUNGUNYA virus, VIRAL genomes, CHEMICAL labeling, RNA polymerases, RNA viruses

Ross River virus envelope glycans contribute to disease through activation of the host complement system

Authors: Gunn, Bronwyn M., Jones, Jennifer E., Shabman, Reed S., Whitmore, Alan C., Sarkar, Sanjay, Blevins, Lance K., Morrison, Thomas E., Heise, Mark T.

Source: In Virology February 2018 515:250-260

Mouse Models as Resources for Studying Infectious Diseases

Authors: Sarkar, Sanjay, Heise, Mark T.

Source: Clinical therapeutics. 41(10):1912-1922

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100113308919.0x000001&indx=1&recIds=ETOCvdc_100113308919.0x000001

Nanoformulated Remdesivir with Extremely Low Content of Poly(2‐oxazoline)‐Based Stabilizer for Aerosol Treatment of COVID‐19

Authors: Ramsey, Jacob D., Stewart, Ian E., Madden, Emily A., Lim, Chaemin, Hwang, Duhyeong, Heise, Mark T., Hickey, Anthony J., Kabanov, Alexander V.

Source: Macromolecular bioscience. 22(8)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100158339628.0x000001&indx=1&recIds=ETOCvdc_100158339628.0x000001

Structure Activity of β-Amidomethyl Vinyl Sulfones as Covalent Inhibitors of ChikungunyansP2 Cysteine Protease with Antialphavirus Activity

Authors: Ghoshal, Anirban, Asressu, Kesatebrhan Haile, Hossain, Mohammad Anwar, Brown, Peter J., Nandakumar, Meganathan, Vala, Anand, Merten, Eric M., Sears, John D., Law, Isabella, Burdick, Jane E., Morales, Noah L., Perveen, Sumera, Pearce, Kenneth H., Popov, Konstantin I., Moorman, Nathaniel J., Heise, Mark T., Willson, Timothy M.

Source: Journal of Medicinal Chemistry; September 2024, Vol. 67 Issue: 18 p16505-16532, 28p

A 44-Nucleotide Region in the Chikungunya Virus 3′ UTR Dictates Viral Fitness in Disparate Host Cells.

Authors: Ander, Stephanie E., Carpentier, Kathryn S., Sanders, Wes, Lucas, Cormac J., Jolly, Austin J., Johnson, Cydney N., Hawman, David W., Heise, Mark T., Moorman, Nathaniel J., Morrison, Thomas E.

Source: Viruses (1999-4915); Jun2024, Vol. 16 Issue 6, p861, 10p

Subject Terms: CHIKUNGUNYA virus, TYPE I interferons, VIRAL mutation

U-CAN-seq: A Universal Competition Assay by Nanopore Sequencing.

Authors: Diaz, Jennifer, Sears, John, Chang, Che-Kang, Burdick, Jane, Law, Isabella, Sanders, Wes, Linnertz, Colton, Sylvester, Paul, Moorman, Nathaniel, Ferris, Martin T., Heise, Mark T.

Source: Viruses (1999-4915); Apr2024, Vol. 16 Issue 4, p636, 11p

Subject Terms: BINDING site assay, BIOLOGICAL fitness, CHIKUNGUNYA virus, RNA viruses, VIRAL mutation

Genetic control of alphavirus pathogenesis

Authors: Baxter, Victoria K., Heise, Mark T.

Source: Mammalian genome. 29(7-8):408-424

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100164377797.0x000001&indx=1&recIds=ETOCvdc_100164377797.0x000001

Animal Models of Chikungunya Virus Infection and Disease

Authors: Haese, Nicole N., Broeckel, Rebecca M., Hawman, David W., Heise, Mark T., Morrison, Thomas E., Streblow, Daniel N.

Source: The Journal of Infectious Diseases, 2016 Dec . 214, S482-S487.

Access URL: https://www.jstor.org/stable/26166669