RIPK1 activates distinct gasdermins in macrophages and neutrophils upon pathogen blockade of innate immune signaling

Authors: Chen, Kaiwen W., Demarco, Benjamin, Ramos, Saray, Heilig, Rosalie, Goris, Michiel, Grayczyk, James P., Assenmacher, Charles-Antoine, Radaelli, Enrico, Joannas, Leonel D., Henao-Mejia, Jorge, Tacchini-Cottier, Fabienne, Brodsky, Igor E., Broz, Petr

Source: Proceedings of the National Academy of Sciences of the United States of America, 2021 Jul . 118(28), 1-9.

Access URL: https://www.jstor.org/stable/27052461

Mitochondrial dynamics regulate genome stability via control of caspase-dependent DNA damage

Authors: Cao, Kai, Riley, Joel S., Heilig, Rosalie, Montes-Gómez, Alfredo E., Vringer, Esmee, Berthenet, Kevin, Cloix, Catherine, Elmasry, Yassmin, Spiller, David G., Ichim, Gabriel, Campbell, Kirsteen J., Gilmore, Andrew P., Tait, Stephen W.G.

Source: In Developmental Cell 23 May 2022 57(10):1211-1225

ESCRT-dependent membrane repair negatively regulates pyroptosis downstream of GSDMD activation

Authors: Rühl, Sebastian, Shkarina, Kateryna, Demarco, Benjamin, Heilig, Rosalie, Santos, José Carlos, Broz, Petr

Source: Science, 2018 Nov . 362(6417), 956-960.

Access URL: https://www.jstor.org/stable/26569287

The Inflammasome Drives GSDMD-Independent Secondary Pyroptosis and IL-1 Release in the Absence of Caspase-1 Protease Activity

Authors: Schneider, Katharina S., Groß, Christina J., Dreier, Roland F., Saller, Benedikt S., Mishra, Ritu, Gorka, Oliver, Heilig, Rosalie, Meunier, Etienne, Dick, Mathias S., Ćiković, Tamara, Sodenkamp, Jan, Médard, Guillaume, Naumann, Ronald, Ruland, Jürgen, Kuster, Bernhard, Broz, Petr, Groß, Olaf

Source: In Cell Reports 26 December 2017 21(13):3846-3859

Mitochondrial outer membrane integrity regulates a ubiquitin-dependent and NF-κB-mediated inflammatory response.

Authors: Vringer, Esmee^1,2 (AUTHOR), Heilig, Rosalie^1,2 (AUTHOR), Riley, Joel S^1,2,3 (AUTHOR), Black, Annabel^1,2 (AUTHOR), Cloix, Catherine^1,2 (AUTHOR), Skalka, George^1,2 (AUTHOR), Montes-Gómez, Alfredo E^1,2 (AUTHOR), Aguado, Aurore^1,2 (AUTHOR), Lilla, Sergio² (AUTHOR), Walczak, Henning^4,5,6 (AUTHOR), Gyrd-Hansen, Mads⁷ (AUTHOR), Murphy, Daniel J^1,2 (AUTHOR), Huang, Danny T^1,2 (AUTHOR), Zanivan, Sara^1,2 (AUTHOR), Tait, Stephen WG^1,2 (AUTHOR) stephen.tait@glasgow.ac.uk

Source: EMBO Journal. Mar2024, Vol. 43 Issue 6, p904-930. 27p.

Subject Terms: *MITOCHONDRIAL membranes, *MITOCHONDRIAL proteins, *INFLAMMATION, *MEMBRANE proteins, *CELL death, *ADAPTOR proteins, *CYTOCHROME c

Human GBP1 binds LPS to initiate assembly of a caspase-4 activating platform on cytosolic bacteria

Authors: Santos, José Carlos, Boucher, Dave, Schneider, Larisa Kapinos, Demarco, Benjamin, Dilucca, Marisa, Shkarina, Kateryna, Heilig, Rosalie, Chen, Kaiwen W., Lim, Roderick Y. H., Broz, Petr

Source: Nature communications. 11(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100174586586.0x000001&indx=1&recIds=ETOCvdc_100174586586.0x000001

Extrinsic and intrinsic apoptosis activate pannexin‐1 to drive NLRP3 inflammasome assembly

Authors: Chen, Kaiwen W, Demarco, Benjamin, Heilig, Rosalie, Shkarina, Kateryna, Boettcher, Andreas, Farady, Christopher J, Pelczar, Pawel, Broz, Petr

Source: EMBO journal. 38(10)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100085866731.0x000001&indx=1&recIds=ETOCvdc_100085866731.0x000001

Mitochondrial DNA in cell death and inflammation.

Authors: Heilig, Rosalie^1,2 rosalie.heilig@glasgow.ac.uk, Lee, Jordan^1,2, Tait, Stephen W. G.^1,2 stephen.tait@glasgow.ac.uk

Source: Biochemical Society Transactions. Feb2023, Vol. 51 Issue 1, p457-472. 16p.

Human GBP1 binds LPS to initiate assembly of a caspase-4 activating platform on cytosolic bacteria

Authors: Carlos Santos, José, Boucher, Dave, Schneider, Larisa Kapinos, Demarco, Benjamin, Dilucca, Marisa, Shkarina, Kateryna, Heilig, Rosalie, Chen, Kaiwen W., Lim, Roderick Y. H., Broz, Petr

Source: Nature Communications; 6/24/2020, Vol. 11 Issue 1, p1-15, 15p

This result is not displayed to guests.
Login for full access.

This result is not displayed to guests.
Login for full access.

This result is not displayed to guests.
Login for full access.

This result is not displayed to guests.
Login for full access.

This result is not displayed to guests.
Login for full access.