Dynamic changes of extracellular vesicles during zebrafish organogenesis

Authors: Linda-Marie Mulzer, Tim Felger, Luis E. Muñoz, Gesa Engl, Heiko Reutter, Mario Schiffer, Leila Pourtalebi Jahromi, Fanni Annamária Boros, Friederike Zunke, Philipp Arnold, Alina C. Hilger

Source: Cell Communication and Signaling, Vol 23, Iss 1, Pp 1-10 (2025)

Subject Terms: Medicine, Cytology, QH573-671

File Description: electronic resource

Relation: https://doaj.org/toc/1478-811X

Access URL: https://doaj.org/article/ef02f347753c42809c653bad9d219933

EZH2 specifically regulates ISL1 during embryonic urinary tract formation

Authors: Enrico Mingardo, Jeshurun C. Kalanithy, Gabriel Dworschak, Nina Ishorst, Öznur Yilmaz, Tobias Lindenberg, Ronja Hollstein, Tim Felger, Pierre-Olivier Angrand, Heiko Reutter, Benjamin Odermatt

Source: Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)

Subject Terms: Classic bladder exstrophy, HEK293, Zebrafish, Promoter, ISL1, EZH2, Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/08a17c2b22034bc68e4a496f25207eee

Ultrasound Super‐Resolution Imaging of Neonatal Cerebral Vascular Reorganization

Authors: Simone Schwarz, Louise Denis, Emmanuel Nedoschill, Adrian Buehler, Vera Danko, Alina C. Hilger, Francisco Brevis Nuñez, Nikola R. Dürr, Martin Schlunz‐Hendann, Friedhelm Brassel, Ursula Felderhoff‐Müser, Heiko Reutter, Joachim Woelfle, Jörg Jüngert, Christian Dohna‐Schwake, Nora Bruns, Adrian P. Regensburger, Olivier Couture, Henriette Mandelbaum, Ferdinand Knieling

Source: Advanced Science, Vol 12, Iss 12, Pp n/a-n/a (2025)

Subject Terms: CEUS, microbubbles, super‐resolution imaging, ultrasound localization microscopy, ultrasound, Vein of Galen malformation, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2198-3844

Access URL: https://doaj.org/article/ec2ec5dd090e464ca5726cf15984e315

First postnatal lactate blood levels on day 1 and outcome of preterm infants with gestational age

Authors: Stephanie Zipf, Ingmar Fortmann, Christoph Härtel, Oliver Andres, Eric Frieauff, Pia Paul, Anna Häfke, Heiko Reutter, Patrick Morhart, Ursula Weller, Amrei Welp, Henry Kipke, Egbert Herting, Alexander Humberg, Wolfgang Göpel, Kathrin Hanke

Source: Frontiers in Pediatrics, Vol 12 (2024)

Subject Terms: lactate levels, small for gestational age, extremely preterm infants, intraventricular haemorrhage, bronchopulmonary dysplasia, all-cause mortality, Pediatrics, RJ1-570

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fped.2024.1443066/full; https://doaj.org/toc/2296-2360

Access URL: https://doaj.org/article/c6f3ef521a784b298fbe0d07dd2edad5

Bi-allelic variants in CELSR3 are implicated in central nervous system and urinary tract anomalies

Authors: Jil D. Stegmann, Jeshurun C. Kalanithy, Gabriel C. Dworschak, Nina Ishorst, Enrico Mingardo, Filipa M. Lopes, Yee Mang Ho, Phillip Grote, Tobias T. Lindenberg, Öznur Yilmaz, Khadija Channab, Steve Seltzsam, Shirlee Shril, Friedhelm Hildebrandt, Felix Boschann, André Heinen, Angad Jolly, Katherine Myers, Kim McBride, Mir Reza Bekheirnia, Nasim Bekheirnia, Marcello Scala, Manuela Morleo, Vincenzo Nigro, Annalaura Torella, TUDP consortium, Michele Pinelli, Valeria Capra, Andrea Accogli, Silvia Maitz, Alice Spano, Rory J. Olson, Eric W. Klee, Brendan C. Lanpher, Se Song Jang, Jong-Hee Chae, Philipp Steinbauer, Dietmar Rieder, Andreas R. Janecke, Julia Vodopiutz, Ida Vogel, Jenny Blechingberg, Jennifer L. Cohen, Kacie Riley, Victoria Klee, Laurence E. Walsh, Matthias Begemann, Miriam Elbracht, Thomas Eggermann, Arzu Stoppe, Kyra Stuurman, Marjon van Slegtenhorst, Tahsin Stefan Barakat, Maureen S. Mulhern, Tristan T. Sands, Cheryl Cytrynbaum, Rosanna Weksberg, Federica Isidori, Tommaso Pippucci, Giulia Severi, Francesca Montanari, Michael C. Kruer, Somayeh Bakhtiari, Hossein Darvish, Heiko Reutter, Gregor Hagelueken, Matthias Geyer, Adrian S. Woolf, Jennifer E. Posey, James R. Lupski, Benjamin Odermatt, Alina C. Hilger

Source: npj Genomic Medicine, Vol 9, Iss 1, Pp 1-12 (2024)

Subject Terms: Medicine, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/2056-7944

Access URL: https://doaj.org/article/70ae196c8ca74a8b9e9771ee7476f1a8

Diving into the Digital Landscape: Assessing the Quality of Online Information on Neonatal Jaundice for Parents

Authors: Michael Karl Baumgartner, Anna-Lena Behr, Anne Christina Garbe, Christoph Quatember, Heiko Reutter, Joachim Woelfle, Fabian Benedikt Fahlbusch, Gregor Hanslik

Source: Children, Vol 11, Iss 7, p 877 (2024)

Subject Terms: jaundice, online information, neonatal care, Pediatrics, RJ1-570

File Description: electronic resource

Relation: https://www.mdpi.com/2227-9067/11/7/877; https://doaj.org/toc/2227-9067

Access URL: https://doaj.org/article/b8701792421644ef81240e1d0a4dd4f6

Familial congenital lower urinary tract obstruction (LUTO) suggested by screening for lower urinary tract dysfunction in parents of patients: A descriptive study

Authors: Fabian Ebach, Pauline Wagner, Raimund Stein, Ramona Dolscheid‐Pommerich, Heiko Reutter, Alina C. Hilger

Source: Health Science Reports, Vol 7, Iss 3, Pp n/a-n/a (2024)

Subject Terms: familial LUTO, IPSS, LUTO, obstructive uropathy, postvoid residual volume, PUV, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/2398-8835

Access URL: https://doaj.org/article/ae07052b02d747bb98aa6a18bb64ac54

Modelling human lower urinary tract malformations in zebrafish

Authors: Caroline M. Kolvenbach, Gabriel C. Dworschak, Johanna M. Rieke, Adrian S. Woolf, Heiko Reutter, Benjamin Odermatt, Alina C. Hilger

Source: Molecular and Cellular Pediatrics, Vol 10, Iss 1, Pp 1-7 (2023)

Subject Terms: Pediatrics, RJ1-570

File Description: electronic resource

Relation: https://doaj.org/toc/2194-7791

Access URL: https://doaj.org/article/dc620dcacdf24d3b958ada1a32327869

A genome-wide association study with tissue transcriptomics identifies genetic drivers for classic bladder exstrophy

Authors: Enrico Mingardo, Glenda Beaman, Philip Grote, Agneta Nordenskjöld, William Newman, Adrian S. Woolf, Markus Eckstein, Alina C. Hilger, Gabriel C. Dworschak, Wolfgang Rösch, Anne-Karolin Ebert, Raimund Stein, Alfredo Brusco, Massimo Di Grazia, Ali Tamer, Federico M. Torres, Jose L. Hernandez, Philipp Erben, Carlo Maj, Jose M. Olmos, Jose A. Riancho, Carmen Valero, Isabel C. Hostettler, Henry Houlden, David J. Werring, Johannes Schumacher, Jan Gehlen, Ann-Sophie Giel, Benedikt C. Buerfent, Samara Arkani, Elisabeth Åkesson, Emilia Rotstein, Michael Ludwig, Gundela Holmdahl, Elisa Giorgio, Alfredo Berettini, David Keene, Raimondo M. Cervellione, Nina Younsi, Melissa Ortlieb, Josef Oswald, Bernhard Haid, Martin Promm, Claudia Neissner, Karin Hirsch, Maximilian Stehr, Frank-Mattias Schäfer, Eberhard Schmiedeke, Thomas M. Boemers, Iris A. L. M. van Rooij, Wouter F. J. Feitz, Carlo L. M. Marcelis, Martin Lacher, Jana Nelson, Benno Ure, Caroline Fortmann, Daniel P. Gale, Melanie M. Y. Chan, Kerstin U. Ludwig, Markus M. Nöthen, Stefanie Heilmann, Nadine Zwink, Ekkehart Jenetzky, Benjamin Odermatt, Michael Knapp, Heiko Reutter

Source: Communications Biology, Vol 5, Iss 1, Pp 1-11 (2022)

Subject Terms: Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/2399-3642

Access URL: https://doaj.org/article/3185cad232344b7081367260f4859843

Identification of de novo variants in nonsyndromic cleft lip with/without cleft palate patients with low polygenic risk scores

Authors: Nina Ishorst, Leonie Henschel, Frederic Thieme, Dmitriy Drichel, Sugirthan Sivalingam, Sarah L. Mehrem, Ariane C. Fechtner, Julia Fazaal, Julia Welzenbach, André Heimbach, Carlo Maj, Oleg Borisov, Jonas Hausen, Ruth Raff, Alexander Hoischen, Michael Dixon, Alvaro Rada‐Iglesias, Michaela Bartusel, Augusto Rojas‐Martinez, Khalid Aldhorae, Bert Braumann, Teresa Kruse, Christian Kirschneck, Gerrit Spanier, Heiko Reutter, Stefanie Nowak, Lina Gölz, Michael Knapp, Andreas Buness, Peter Krawitz, Markus M. Nöthen, Michael Nothnagel, Tim Becker, Kerstin U. Ludwig, Elisabeth Mangold

Source: Molecular Genetics & Genomic Medicine, Vol 11, Iss 3, Pp n/a-n/a (2023)

Subject Terms: candidate genes, de novo variants, exome sequencing, nonsyndromic cleft lip with/without cleft palate, polygenic risk, single‐molecule molecular inversion probes, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/2324-9269

Access URL: https://doaj.org/article/205be1f83d914d678ac7257527a61a58

Premature birth associated with a favorable course in gestational alloimmune liver disease (GALD): A case report

Authors: Linda-Marie Mulzer, Heiko Reutter, Jörg Jüngert, A. S. Knisely, Margit Schmid, André Hoerning, Patrick Morhart

Source: Frontiers in Pediatrics, Vol 11 (2023)

Subject Terms: gestational alloimmune liver disease, liver disease, neonatal acute liver failure, prematurity, neonatal hemochromatosis, prematurit, Pediatrics, RJ1-570

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fped.2023.1104530/full; https://doaj.org/toc/2296-2360

Access URL: https://doaj.org/article/5c560a1f817d4573bc3d56aa28a907c6

Diagnostic Utility of Interleukin-6 in Early-Onset Sepsis among Term Newborns: Impact of Maternal Risk Factors and CRP Evaluation

Authors: Maria Schleier, Julia Lubig, Sven Kehl, Steven Hébert, Joachim Woelfle, Adriana van der Donk, Alisa Bär, Heiko Reutter, Tobias Hepp, Patrick Morhart

Source: Children, Vol 11, Iss 1, p 53 (2023)

Subject Terms: sepsis, neonatal, early-onset sepsis, EOS, Interleukin-6, C-reactive protein, Pediatrics, RJ1-570

File Description: electronic resource

Relation: https://www.mdpi.com/2227-9067/11/1/53; https://doaj.org/toc/2227-9067

Access URL: https://doaj.org/article/5cb8a98a562b41ce81134702ba74bb7b

'Multisystem Inflammatory Syndrome in Children'-Like Disease after COVID-19 Vaccination (MIS-V) with Potential Significance of Functional Active Autoantibodies Targeting G-Protein-Coupled Receptors (GPCR-fAAb) for Pathophysiology and Therapy

Authors: Marius Schmidt, Steven Hébert, Gerd Wallukat, Rolf Ponader, Tobias Krickau, Matthias Galiano, Heiko Reutter, Joachim Woelfle, Abbas Agaimy, Christian Mardin, André Hoerning, Bettina Hohberger

Source: Children, Vol 10, Iss 12, p 1836 (2023)

Subject Terms: COVID-19, SARS-CoV-2, MIS-V, GPCR-fAAb, MIS-C, PIMS, Pediatrics, RJ1-570

File Description: electronic resource

Relation: https://www.mdpi.com/2227-9067/10/12/1836; https://doaj.org/toc/2227-9067

Access URL: https://doaj.org/article/7fc131e2481744609c8740d610214e9d

Application of Next-Generation Sequencing to Enterobacter Hormaechei Subspecies Analysis during a Neonatal Intensive Care Unit Outbreak

Authors: Patrick Morhart, Roman G. Gerlach, Caroline Kunz, Jürgen Held, Giuseppe Valenza, Joachim Wölfle, Heiko Reutter, Gregor J. Hanslik, Fabian B. Fahlbusch

Source: Children, Vol 10, Iss 10, p 1696 (2023)

Subject Terms: Enterobacter, MRGN, ECC, NICU, NGS, WGS, Pediatrics, RJ1-570

File Description: electronic resource

Relation: https://www.mdpi.com/2227-9067/10/10/1696; https://doaj.org/toc/2227-9067

Access URL: https://doaj.org/article/4bfb245a5adf4a33b371cd5e4321743d

'Multisystem Inflammatory Syndrome in Children' (MIS-C) after COVID-19 Infection in the Metropolitan Area of Nuremberg-Erlangen, Germany—Expectations and Results of a Two-Year Period

Authors: Steven Hébert, Marius Schmidt, Georg Topf, Daniel Rieger, Jens Klinge, Jan Vermehren, Christoph Fusch, Christian Grillhösl, Michael Schroth, Irmgard Toni, Heiko Reutter, Patrick Morhart, Gregor Hanslik, Linda Mulzer, Joachim Woelfle, Bettina Hohberger, André Hoerning

Source: Children, Vol 10, Iss 8, p 1363 (2023)

Subject Terms: IVIG, intravenous immunoglobulins, MIS-C, Multisystem Inflammatory Syndrome in children, mAbs, monoclonal antibodies, Pediatrics, RJ1-570

File Description: electronic resource

Relation: https://www.mdpi.com/2227-9067/10/8/1363; https://doaj.org/toc/2227-9067

Access URL: https://doaj.org/article/a906d8a5f2c74ee98746e35cc42525dd

Exome Survey and Candidate Gene Re-Sequencing Identifies Novel Exstrophy Candidate Genes and Implicates LZTR1 in Disease Formation

Authors: Ricarda Köllges, Jil Stegmann, Sophia Schneider, Lea Waffenschmidt, Julia Fazaal, Katinka Breuer, Alina C. Hilger, Gabriel C. Dworschak, Enrico Mingardo, Wolfgang Rösch, Aybike Hofmann, Claudia Neissner, Anne-Karolin Ebert, Raimund Stein, Nina Younsi, Karin Hirsch-Koch, Eberhard Schmiedeke, Nadine Zwink, Ekkehart Jenetzky, Holger Thiele, Kerstin U. Ludwig, Heiko Reutter

Source: Biomolecules, Vol 13, Iss 7, p 1117 (2023)

Subject Terms: exome analysis, molecular inversion probe, exstrophy, cloacal exstrophy, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.mdpi.com/2218-273X/13/7/1117; https://doaj.org/toc/2218-273X

Access URL: https://doaj.org/article/74b382b7c34646239735014ee1312e5a

Parental risk factors for congenital diaphragmatic hernia – a large German case-control study

Authors: Felicitas Schulz, Ekkehart Jenetzky, Nadine Zwink, Charlotte Bendixen, Florian Kipfmueller, Neysan Rafat, Andreas Heydweiller, Lucas Wessel, Heiko Reutter, Andreas Mueller, Thomas Schaible

Source: BMC Pediatrics, Vol 21, Iss 1, Pp 1-8 (2021)

Subject Terms: Birth defect, CDH, Congenital diaphragmatic hernia, Environmental risk factor, Pediatrics, RJ1-570

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2431

Access URL: https://doaj.org/article/8f5f3fdfac5c4967aecc5710413a8ed6

Genome-wide association study in patients with posterior urethral valves

Authors: Loes F. M. van der Zanden, Carlo Maj, Oleg Borisov, Iris A. L. M. van Rooij, Josine S. L. T. Quaedackers, Martijn Steffens, Luca Schierbaum, Sophia Schneider, Lea Waffenschmidt, Lambertus A. L. M. Kiemeney, Liesbeth L. L. de Wall, Stefanie Heilmann, Aybike Hofmann, Jan Gehlen, Johannes Schumacher, Maria Szczepanska, Katarzyna Taranta-Janusz, Pawel Kroll, Grazyna Krzemien, Agnieszka Szmigielska, Michiel F. Schreuder, Stefanie Weber, Marcin Zaniew, Nel Roeleveld, Heiko Reutter, Wout F. J. Feitz, Alina C. Hilger

Source: Frontiers in Pediatrics, Vol 10 (2022)

Subject Terms: genome wide association study, lower urinary tract obstruction, obstructive uropathy, posterior urethral valves, PCDH9, SALL1, Pediatrics, RJ1-570

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fped.2022.988374/full; https://doaj.org/toc/2296-2360

Access URL: https://doaj.org/article/2b86e5686ed44e1c9b5c76e66ebae75d

First genome-wide association study of esophageal atresia identifies three genetic risk loci at CTNNA3, FOXF1/FOXC2/FOXL1, and HNF1B

Authors: Jan Gehlen, Ann-Sophie Giel, Ricarda Köllges, Stephan L. Haas, Rong Zhang, Jiri Trcka, Ayse Ö. Sungur, Florian Renziehausen, Dorothea Bornholdt, Daphne Jung, Paul D. Hoyer, Agneta Nordenskjöld, Dick Tibboel, John Vlot, Manon C.W. Spaander, Robert Smigiel, Dariusz Patkowski, Nel Roeleveld, Iris ALM. van Rooij, Ivo de Blaauw, Alice Hölscher, Marcus Pauly, Andreas Leutner, Joerg Fuchs, Joel Niethammer, Maria-Theodora Melissari, Ekkehart Jenetzky, Nadine Zwink, Holger Thiele, Alina Christine Hilger, Timo Hess, Jessica Trautmann, Matthias Marks, Martin Baumgarten, Gaby Bläss, Mikael Landén, Bengt Fundin, Cynthia M. Bulik, Tracie Pennimpede, Michael Ludwig, Kerstin U. Ludwig, Elisabeth Mangold, Stefanie Heilmann-Heimbach, Susanne Moebus, Bernhard G. Herrmann, Kristina Alsabeah, Carmen M. Burgos, Helene E. Lilja, Sahar Azodi, Pernilla Stenström, Einar Arnbjörnsson, Barbora Frybova, Dariusz M. Lebensztejn, Wojciech Debek, Elwira Kolodziejczyk, Katarzyna Kozera, Jaroslaw Kierkus, Piotr Kaliciński, Marek Stefanowicz, Anna Socha-Banasiak, Michal Kolejwa, Anna Piaseczna-Piotrowska, Elzbieta Czkwianianc, Markus M. Nöthen, Phillip Grote, Michal Rygl, Konrad Reinshagen, Nicole Spychalski, Barbara Ludwikowski, Jochen Hubertus, Andreas Heydweiller, Benno Ure, Oliver J. Muensterer, Ophelia Aubert, Jan-Hendrik Gosemann, Martin Lacher, Petra Degenhardt, Thomas M. Boemers, Anna Mokrowiecka, Ewa Małecka-Panas, Markus Wöhr, Michael Knapp, Guido Seitz, Annelies de Klein, Grzegorz Oracz, Erwin Brosens, Heiko Reutter, Johannes Schumacher

Source: HGG Advances, Vol 3, Iss 2, Pp 100093- (2022)

Subject Terms: genome-wide association study (GWAS), esophageal atresia (EA), multifactorial diseases, CTNNA3, FOXF1/FOXC2/FOXL1, HNF1B, Genetics, QH426-470

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2666247722000094; https://doaj.org/toc/2666-2477

Access URL: https://doaj.org/article/e9a5e2a8eb8e4559958fd4286f773ad1

Nonurgent Visits to the Pediatric Emergency Department before and during the First Peak of the COVID-19 Pandemic

Authors: Laura Guckert, Heiko Reutter, Nadia Saleh, Rainer Ganschow, Andreas Müller, Fabian Ebach

Source: International Journal of Pediatrics, Vol 2022 (2022)

Subject Terms: Pediatrics, RJ1-570

File Description: electronic resource

Relation: https://doaj.org/toc/1687-9759

Access URL: https://doaj.org/article/1bfff52101d6413b834617fae3984a85