JBP1 and JBP3 have conserved structures but different affinity to base-J

Authors: de Vries, Ida ¹, Adamopoulos, Athanassios ¹, Kazokaitė-Adomaitienė, Justina, Heidebrecht, Tatjana, Fish, Alex, Celie, Patrick H.N., Joosten, Robbie P., Perrakis, Anastassis ^⁎

Source: In Journal of Structural Biology March 2025 217(1)

Target highlights in CASP14: Analysis of models by structure providers

Authors: Alexander, Leila T., Lepore, Rosalba, Kryshtafovych, Andriy, Adamopoulos, Athanassios, Alahuhta, Markus, Arvin, Ann M., Bomble, Yannick J., Böttcher, Bettina, Breyton, Cécile, Chiarini, Valerio, Chinnam, Naga babu, Chiu, Wah, Fidelis, Krzysztof, Grinter, Rhys, Gupta, Gagan D., Hartmann, Marcus D., Hayes, Christopher S., Heidebrecht, Tatjana, Ilari, Andrea, Joachimiak, Andrzej, Kim, Youngchang, Linares, Romain, Lovering, Andrew L., Lunin, Vladimir V., Lupas, Andrei N., Makbul, Cihan, Michalska, Karolina, Moult, John, Mukherjee, Prasun K., Nutt, William (Sam), Oliver, Stefan L., Perrakis, Anastassis, Stols, Lucy, Tainer, John A., Topf, Maya, Tsutakawa, Susan E., Valdivia‐Delgado, Mauricio, Schwede, Torsten

Source: Proteins. 89(12):1647-1672

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100134836094.0x000001&indx=1&recIds=ETOCvdc_100134836094.0x000001

The domain architecture of the protozoan protein J-DNA–binding protein 1 suggests synergy between base J DNA binding and thymidine hydroxylase activity

Authors: Adamopoulos, Athanassios, Heidebrecht, Tatjana, Roosendaal, Jeroen, Touw, Wouter G., Phan, Isabelle Q., Beijnen, Jos, Perrakis, Anastassis

Source: In Journal of Biological Chemistry 23 August 2019 294(34):12815-12825

Lysophosphatidic acid produced by autotaxin acts as an allosteric modulator of its catalytic efficiency

Authors: Salgado-Polo, Fernando, Fish, Alex, Matsoukas, Minos-Timotheos, Heidebrecht, Tatjana, Keune, Willem-Jan, Perrakis, Anastassis

Source: In Journal of Biological Chemistry September 2018 293(37):14312-14327

Quantitative LC-MS/MS analysis of 5-hydroxymethyl-2′-deoxyuridine to monitor the biological activity of J-binding protein

Authors: Roosendaal, Jeroen, Heidebrecht, Tatjana, Rosing, Hilde, Perrakis, Anastassis, Beijnen, Jos H.

Source: Analytical biochemistry. 610

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100110964205.0x000001&indx=1&recIds=ETOCvdc_100110964205.0x000001

Distant sequence regions of JBP1 contribute to J-DNA binding.

Authors: de Vries, Ida, Ammerlaan, Danique, Heidebrecht, Tatjana, Celie, Patrick H. N., Geerke, Daan P., Joosten, Robbie P., Perrakis, Anastassis

Source: Life Science Alliance; Sep2023, Vol. 6 Issue 9, p1-13, 13p

Glucosylated Hydroxymethyluracil, DNA Base J, Prevents Transcriptional Readthrough in Leishmania

Authors: van Luenen, Henri G.A.M., Farris, Carol, Jan, Sabrina, Genest, Paul-Andre, Tripathi, Pankaj, Velds, Arno, Kerkhoven, Ron M., Nieuwland, Marja, Haydock, Andrew, Ramasamy, Gowthaman, Vainio, Saara, Heidebrecht, Tatjana, Perrakis, Anastassis, Pagie, Ludo, van Steensel, Bas, Myler, Peter J., Borst, Piet

Source: In Cell 31 August 2012 150(5):909-921

Expression of protein complexes using multiple Escherichia coli protein co-expression systems: A benchmarking study

Authors: Busso, Didier, Peleg, Yoav, Heidebrecht, Tatjana, Romier, Christophe, Jacobovitch, Yossi, Dantes, Ada, Salim, Loubna, Troesch, Edouard, Schuetz, Anja, Heinemann, Udo, Folkers, Gert E., Geerlof, Arie, Wilmanns, Matthias, Polewacz, Andrea, Quedenau, Claudia, Büssow, Konrad, Adamson, Rachel, Blagova, Elena, Walton, Julia, Cartwright, Jared L., Bird, Louise E., Owens, Raymond J., Berrow, Nick S., Wilson, Keith S., Sussman, Joel L., Perrakis, Anastassis, Celie, Patrick H.N.

Source: In Journal of Structural Biology August 2011 175(2):159-170

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Characterization and structure determination of a llama‐derived nanobody targeting the J‐base binding protein 1.

Authors: van Beusekom, Bart¹, Heidebrecht, Tatjana¹, Adamopoulos, Athanassios¹, Fish, Alexander¹, Pardon, Els^2,3, Steyaert, Jan^2,3, Joosten, Robbie P.¹, Perrakis, Anastassis¹ a.perrakis@nki.nl

Source: Acta Crystallographica: Section F, Structural Biology Communications. Nov2018, Vol. 74 Issue 11, p690-695. 6p.

Subject Terms: *CARRIER proteins, *BIOSYNTHESIS, *SURFACE plasmon resonance

Crystal structure of the tubulin tyrosine carboxypeptidase complex VASH1–SVBP

Authors: Adamopoulos, Athanassios, Landskron, Lisa, Heidebrecht, Tatjana, Tsakou, Foteini, Bleijerveld, Onno, Altelaar, Maarten, Nieuwenhuis, Joppe, Celie, Patrick, Brummelkamp, Thijn, Perrakis, Anastassis

Source: Nature Structural and Molecular Biology; July 2019, Vol. 26 Issue: 7 p567-570, 4p

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Posttranslational modification of microtubules by the MATCAP detyrosinase.

Authors: Landskron, Lisa, Bak, Jitske, Adamopoulos, Athanassios, Kaplani, Konstantina, Moraiti, Maria, van den Hengel, Lisa G., Ji-Ying Song, Bleijerveld, Onno B., Nieuwenhuis, Joppe, Heidebrecht, Tatjana, Henneman, Linda, Moutin, Marie-Jo, Barisic, Marin, Taraviras, Stavros, Perrakis, Anastassis, a.perrakis@nki.nl, Brummelkamp, Thijn R., t.brummelkamp@nki.nl

Source: Science; 5/20/2022, Vol. 376 Issue 6595, p815-815, 1p, 1 Color Photograph