Role of aldo-keto reductases and other doxorubicin pharmacokinetic genes in doxorubicin resistance, DNA binding, and subcellular localization

Authors: Heibein Allan D, Guo Baoqing, Sprowl Jason A, MacLean David A, Parissenti Amadeo M

Source: BMC Cancer, Vol 12, Iss 1, p 381 (2012)

Subject Terms: Doxorubicin, Resistance, Gene profiling, PharmGKB, Pharmacokinetics, Aldo-keto reductases, Cytotoxicity, Lysosome, DNA-binding, Drug localization, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://www.biomedcentral.com/1471-2407/12/381; https://doaj.org/toc/1471-2407

Access URL: https://doaj.org/article/94424e47552e4944adca62a42360b985

Induction of 1C aldoketoreductases and other drug dose-dependent genes upon acquisition of anthracycline resistance

Authors: Veitch, Zachary W., Guo, Baoqing, Hembruff, Stacey L., Bewick, Adam J., Heibein, Allan D., Eng, Jamei, Cull, Stephanie, Maclean, David A., Parissenti, Amadeo M.

Source: Pharmacogenetics and Genomics; June 2009, Vol. 19 Issue: 6 p477-488, 12p