Apple Intelligence Foundation Language Models

Authors: Gunter, Tom, Wang, Zirui, Wang, Chong, Pang, Ruoming, Narayanan, Andy, Zhang, Aonan, Zhang, Bowen, Chen, Chen, Chiu, Chung-Cheng, Qiu, David, Gopinath, Deepak, Yap, Dian Ang, Yin, Dong, Nan, Feng, Weers, Floris, Yin, Guoli, Huang, Haoshuo, Wang, Jianyu, Lu, Jiarui, Peebles, John, Ye, Ke, Lee, Mark, Du, Nan, Chen, Qibin, Keunebroek, Quentin, Wiseman, Sam, Evans, Syd, Lei, Tao, Rathod, Vivek, Kong, Xiang, Du, Xianzhi, Li, Yanghao, Wang, Yongqiang, Gao, Yuan, Ahmed, Zaid, Xu, Zhaoyang, Lu, Zhiyun, Rashid, Al, Jose, Albin Madappally, Doane, Alec, Bencomo, Alfredo, Vanderby, Allison, Hansen, Andrew, Jain, Ankur, Anupama, Anupama Mann, Kamal, Areeba, Wu, Bugu, Brum, Carolina, Maalouf, Charlie, Erdenebileg, Chinguun, Dulhanty, Chris, Moritz, Dominik, Kang, Doug, Jimenez, Eduardo, Ladd, Evan, Shi, Fangping, Bai, Felix, Chu, Frank, Hohman, Fred, Kotek, Hadas, Coleman, Hannah Gillis, Li, Jane, Bigham, Jeffrey, Cao, Jeffery, Lai, Jeff, Cheung, Jessica, Shan, Jiulong, Zhou, Joe, Li, John, Qin, Jun, Singh, Karanjeet, Vega, Karla, Zou, Kelvin, Heckman, Laura, Gardiner, Lauren, Bowler, Margit, Cordell, Maria, Cao, Meng, Hay, Nicole, Shahdadpuri, Nilesh, Godwin, Otto, Dighe, Pranay, Rachapudi, Pushyami, Tantawi, Ramsey, Frigg, Roman, Davarnia, Sam, Shah, Sanskruti, Guha, Saptarshi, Sirovica, Sasha, Ma, Shen, Ma, Shuang, Wang, Simon, Kim, Sulgi, Jayaram, Suma, Shankar, Vaishaal, Paidi, Varsha, Kumar, Vivek, Wang, Xin, Zheng, Xin, Cheng, Walker, Shrager, Yael, Ye, Yang, Tanaka, Yasu, Guo, Yihao, Meng, Yunsong, Luo, Zhao Tang, Ouyang, Zhi, Aygar, Alp, Wan, Alvin, Walkingshaw, Andrew, Lin, Antonie, Farooq, Arsalan, Ramerth, Brent, Reed, Colorado, Bartels, Chris, Chaney, Chris, Riazati, David, Yang, Eric Liang, Feldman, Erin, Hochstrasser, Gabriel, Seguin, Guillaume, Belousova, Irina, Pelemans, Joris, Yang, Karen, Vahid, Keivan Alizadeh, Cao, Liangliang, Najibi, Mahyar, Zuliani, Marco, Horton, Max, Cho, Minsik, Bhendawade, Nikhil, Dong, Patrick, Maj, Piotr, Agrawal, Pulkit, Shan, Qi, Fu, Qichen, Poston, Regan, Xu, Sam, Liu, Shuangning, Rao, Sushma, Heeramun, Tashweena, Merth, Thomas, Rayala, Uday, Cui, Victor, Sridhar, Vivek Rangarajan, Zhang, Wencong, Zhang, Wenqi, Wu, Wentao, Zhou, Xingyu, Liu, Xinwen, Zhao, Yang, Xia, Yin, Ren, Zhile, Ren, Zhongzheng

Subject Terms: Computer Science - Artificial Intelligence, Computer Science - Computation and Language, Computer Science - Machine Learning

Access URL: http://arxiv.org/abs/2407.21075

Genome-wide distribution of linker histone H1.0 is independent of MeCP2

Authors: Ito-Ishida, Aya, Yamalanchili, Hari, Shao, Yingyao, Baker, Steven, Heckman, Laura, Lavery, Laura, Kim, Ji-yoen, Lombardi, Laura, Sun, Yaling, Liu, Zhandong, Zoghbi, Huda

Source: Nature neuroscience. 21(6):794-798

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100153420794.0x000001&indx=1&recIds=ETOCvdc_100153420794.0x000001

Progranulin AAV gene therapy for frontotemporal dementia: translational studies and phase 1/2 trial interim results

Authors: Sevigny, Jeffrey, Uspenskaya, Olga, Heckman, Laura Dean, Wong, Li Chin, Hatch, Daniel A., Tewari, Ambika, Vandenberghe, Rik, Irwin, David J., Saracino, Dario, Le Ber, Isabelle, Ahmed, Rebekah, Rohrer, Jonathan D., Boxer, Adam L., Boland, Sebastian, Sheehan, Patricia, Brandes, Alissa, Burstein, Suzanne R., Shykind, Benjamin M., Kamalakaran, Sitharthan, Daniels, Carter W., David Litwack, E., Mahoney, Erin, Velaga, Jenny, McNamara, Ilan, Sondergaard, Patricia, Sajjad, Syed A., Kobayashi, Yvonne M., Abeliovich, Asa, Hefti, Franz

Source: Nature Medicine; 20240101, Issue: Preprints p1-10, 10p

PR001 gene therapy increased GCase activity and improved neuronopathic Gaucher disease phenotypes

Authors: Sheehan, Patty, Heckman, Laura D., Fenn, Tim, Wong, Li Chin, Nelson, Stuart, Garimalla, Swetha, Haller, Jorge, Daily, Jennifer, Politi, Jason, Dai, Yong, Hefti, Franz, Abeliovich, Asa

Source: Molecular genetics and metabolism. 132(2):S99-S100

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100135062911.0x000001&indx=1&recIds=ETOCvdc_100135062911.0x000001

PR001 gene therapy increased GCase activity and improved Gaucher disease type 1 phenotypes in mouse models

Authors: Sheehan, Patty, Heckman, Laura D., Wong, Li Chin, Kamalakaran, Sid, Yang, Zhaohui, Lin, Hsuan-Ni, Garimalla, Swetha, Biezonski, Dominik, Hendricks, Jeremiah, Raghunathan, Rekha, Zhao, Zoe, Raut, Priyam, Politi, Jason, Dai, Yong, Abeliovich, Asa, Hefti, Franz

Source: Molecular genetics and metabolism. 135(2):S112-S112

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100154951828.0x000001&indx=1&recIds=ETOCvdc_100154951828.0x000001

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Gene therapy PR001 increased GCase activity and improved neuronopathic Gaucher disease phenotypes in mouse models

Authors: Heckman, Laura D., Sheehan, Patty, Fenn, Tim, Wong, Li Chin, Nelson, Stuart, Garimalla, Swetha, Haller, Jorge, Daily, Jennifer, Politi, Jason, Dai, Yong, Hefti, Franz, Abeliovich, Asa

Source: Molecular genetics and metabolism. 129(2):S70-S71

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100099341834.0x000001&indx=1&recIds=ETOCvdc_100099341834.0x000001

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PR001 gene therapy increased GCase activity and improved Gaucher disease type 1 phenotypes in mouse models

Authors: Sheehan, Patty, Heckman, Laura D., Wong, Li Chin, Yang, Zhaohui, Lin, Hsuan-Ni, Kamalakaran, Sid, Garimalla, Swetha, Politi, Jason, Dai, Yong, Hefti, Franz, Abeliovich, Asa

Source: Molecular genetics and metabolism. 132(2):S100-S100

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100135062858.0x000001&indx=1&recIds=ETOCvdc_100135062858.0x000001

Gene therapy PR006 increased progranulin levels and improved lysosomal related phenotypes in model systems

Authors: Brandes, Alissa, Heckman, Laura D., Wong, Li Chin, Yang, Zhaohui, Fenn, Tim, Nelson, Stuart, Aziz, Zarah, Kamalakaran, Sid, Garimalla, Swetha, Burstein, Suzanne, Haller, Jorge, Politi, Jason, Dai, Yong, Hefti, Franz, Abeliovich, Asa

Source: Molecular genetics and metabolism. 129(2):S34-S34

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100099342977.0x000001&indx=1&recIds=ETOCvdc_100099342977.0x000001

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Preclinical development of PR006, a gene therapy for the treatment of frontotemporal dementia with progranulin mutations: Molecular and cell biology/endosomal‐lysosomal dysfunction.

Authors: Heckman, Laura D., Burstein, Suzanne R., Brandes, Alissa, Wong, Li Chin, Yang, Zhaohui, Lin, Hsuan‐Ni, Fenn, Tim, Nelson, Stuart, Aziz, Zarah, Kamalakaran, Sid, Garimalla, Swetha, Haller, Jorge, Daily, Jenn, Politi, Jason, Dai, Yong, Hefti, Franz, Abeliovich, Asa

Source: Alzheimer's & Dementia: The Journal of the Alzheimer's Association; Dec2020 Supplement S11, Vol. 16 Issue 11, p1-2, 2p

PR001 gene therapy improved phenotypes in models of Parkinson's disease with GBA1 mutation: Molecular and cell biology/endosomal‐lysosomal dysfunction.

Authors: Sheehan, Patty, Heckman, Laura D., Fenn, Tim, Wong, Li Chin, Nelson, Stuart, Garimalla, Swetha, Haller, Jorge, Daily, Jenn, Politi, Jason, Dai, Yong, Hefti, Franz, Abeliovich, Asa

Source: Alzheimer's & Dementia: The Journal of the Alzheimer's Association; Dec2020 Supplement S11, Vol. 16 Issue 11, p1-1, 1p

Chat to us!

Authors: Williams, Elizabeth, Drury, Mari, Gresty, Sammy, Heckman, Laura, Norrie, Selby, Bradshaw, Adam, Lee, Rhianna, Holland, Tuesday, Bateman, Ruth, Cartwright, Helen

Source: Chat; 8/16/2018, Issue 33, p4-5, 2p, 10 Color Photographs

Your Wild week….

Authors: Heckman, Laura, Davidson, Tracy, Campbell, Joanne, Hunt, Debb, Barrett, Shelley, Steer, Nina, Davenport, J., Angus, Sue, Jackson, Diane, Sweetman, Annie, Burns, Yasmin

Source: Pick Me Up; 3/8/2018, Issue 10, p4-5, 2p, 11 Color Photographs

Your Pick Me Ups.

Authors: Price, Jane, Taylor, Michelle, Webber, Eleri, Lever, Emma, Setterfield, Karyn, Johnson, Marunda, Burke, Pauline, Hamori, Christine, Roome, Rebecca, Heckman, Laura, Wigley, Caroline, Mack, Carley, Johnson, Tracey, Gardner, Emma

Source: Pick Me Up; 10/12/2017, Issue 41, p4-5, 2p, 12 Color Photographs

Your Pick Me Ups.

Authors: Wilson, Alan, Angus, Sue, Colworth, Dee, Slinn, Michelle, Cooper, Joni, Clackson, Emma, Milne, Louise, Primrose, Charlotte, Heckman, Laura, Simpson, Julie, Hayes, Steph, Bacon, Mel, Thomas, Margaret

Source: Pick Me Up; 7/20/2017, Issue 29, p4-5, 2p, 11 Color Photographs

Your Pick Me Ups.

Authors: Littlewood, Margaret, Jones, Sam, Truby, Daisy, Finnie, Shaun, Fordham, Vicki, King, Michelle, Heckman, Laura, Ogunjimi, Fiona, Lock, Jane, Brown, Clare, Williams, Lesly, Green, Cass, McCully, Hayley

Source: Pick Me Up; 11/19/2015, Issue 47, p4-5, 2p, 1 Color Photograph

Cute Kids.

Authors: Christie, Kelly, Rigg, Joanne, Heckman, Laura

Source: Chat; 2/22/2018, Issue 8, p42-42, 2/7p, 3 Color Photographs